Shan Yan

发表

Advanced Nanoengineering Approach for Target-Specific, Spatiotemporal, and Ratiometric Delivery of Gemcitabine-Cisplatin Combination for Improved Therapeutic Outcome in Pancreatic Cancer.

Juan L. Vivero-Escoto, P. Mukherjee, Bryce Holmes, 2021, Small.

Genomic alterations and abnormal expression of APE2 in multiple cancers

Xinghua Shi, Shan Yan, K. Jensen, 2020, Scientific Reports.

A novel ubiquitin carboxyl terminal hydrolase is involved in toad oocyte maturation

Zhaogui Sun, Shan Yan, Yan Jun Zhang, 2002, Cell Research.

SENP3 is responsible for HIF‐1 transactivation under mild oxidative stress via p300 de‐SUMOylation

E. Yeh, Chao Huang, Yan Han, 2009, The EMBO journal.

SENP 3 is responsible for HIF-1 transactivation under mild oxidative stress via p 300 de-SUMOylation

E. Yeh, Chao Huang, Yan Han, 2009 .

Redox regulation of the stability of the SUMO protease SENP3 via interactions with CHIP and Hsp90

E. Yeh, Xiangrui Wang, Shan Yan, 2010, The EMBO journal.

Methods for Studying DNA Single-Strand Break Repair and Signaling in Xenopus laevis Egg Extracts.

Shan Yan, Yunfeng Lin, Anh Ha, 2019, Methods in molecular biology.

Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling

Shan Yan, W. Michael, H. D. Lindsay, 2006, The Journal of cell biology.

Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury

Jennifer S. Yu, N. Munshi, T. LaFramboise, 2020, Cancer Research.

APE1 assembles biomolecular condensates to promote the ATR–Chk1 DNA damage response in nucleolus

A. Mcmahon, Shan Yan, Jia Li, 2022, bioRxiv.

APE1 senses DNA single-strand breaks for repair and signaling

Jia Li, P. Mukherjee, C. Richardson, 2019, Nucleic acids research.

Single-Strand Break End Resection in Genome Integrity: Mechanism and Regulation by APE2

Md Akram Hossain, Shan Yan, Yunfeng Lin, 2018, International journal of molecular sciences.

APE1 recruits ATRIP to ssDNA in an RPA-independent manner to promote the ATR DNA damage response

Shan Yan, Yunfeng Lin, Jia Li, 2022, bioRxiv.

Resolution of a complex crisis at DNA 3′ termini

Shan Yan, 2019, Nature Structural & Molecular Biology.

APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress

Shan Yan, Y. Patel, J. Willis, 2013, Proceedings of the National Academy of Sciences.

TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: Implications for a replication restart-based mechanism for ATR checkpoint activation

Shan Yan, W. Michael, 2009, Cell cycle.

Plk1 Phosphorylation of Mre11 Antagonizes the DNA Damage Response.

J. Li, N. Ahmad, Xiaoqi Liu, 2017, Cancer research.

APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress

J. Wojtaszek, R. London, G. Mueller, 2016, Proceedings of the National Academy of Sciences.

Continued primer synthesis at stalled replication forks contributes to checkpoint activation

K. Cimprich, S. Waga, Shan Yan, 2010, The Journal of cell biology.

TopBP1 and DNA polymerase-α directly recruit the 9-1-1 complex to stalled DNA replication forks

Shan Yan, W. Michael, 2009, The Journal of cell biology.

Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress

Shan Yan, Zachary Berman, Melanie S Sorrell, 2014, Cellular and Molecular Life Sciences.

APE2 Is a General Regulator of the ATR-Chk1 DNA Damage Response Pathway to Maintain Genome Integrity in Pancreatic Cancer Cells

Y. Nakabeppu, Jia Li, A. Mcmahon, 2021, Frontiers in Cell and Developmental Biology.

APE2: catalytic function and synthetic lethality draw attention as a cancer therapy target

A. Mcmahon, Shan Yan, Jianjun Zhao, 2023, NAR cancer.

Distinct roles of XRCC1 in genome integrity in Xenopus egg extracts.

Shan Yan, Yunfeng Lin, Steven Cupello, 2019, The Biochemical journal.

APE2 promotes DNA damage response pathway from a single-strand break

Md Akram Hossain, Shan Yan, Liping Bai, 2018, Nucleic acids research.

Cell-free Xenopus egg extracts for studying DNA damage response pathways.

C. Richardson, Shan Yan, Steven Cupello, 2016, The International journal of developmental biology.

Direct Binding to Replication Protein A (RPA)-coated Single-stranded DNA Allows Recruitment of the ATR Activator TopBP1 to Sites of DNA Damage*

Shan Yan, W. Michael, Julyana Acevedo, 2016, The Journal of Biological Chemistry.

Direct binding to RPA-coated ssDNA allows recruitment of the ATR activator TopBP1 to sites of DNA damage

Shan Yan, Julyana Acevedo, M. Michael, 2016, bioRxiv.

TopBP 1 BRCT interaction with RPA-coated ssDNA 1 Direct binding to RPA-coated ssDNA allows recruitment of the ATR activator TopBP 1 to sites of DNA damage

Shan Yan, W. Michael, Julyana Acevedo, 2016 .

REV1 is important for the ATR-Chk1 DNA damage response pathway in Xenopus egg extracts.

Shan Yan, D. Destephanis, Melissa M McLeod, 2015, Biochemical and biophysical research communications.

Importin β-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts.

Shan Yan, W. Michael, Liping Bai, 2014, Cellular signalling.

WD40-repeat protein WDR18 collaborates with TopBP1 to facilitate DNA damage checkpoint signaling.

Shan Yan, J. Willis, Jeremy Willis, 2013, Biochemical and biophysical research communications.

Mechanisms of Ataxia Telangiectasia Mutated (ATM) Control in the DNA Damage Response to Oxidative Stress, Epigenetic Regulation, and Persistent Innate Immune Suppression Following Sepsis

M. Clemens, Laura A. Huff, Shan Yan, 2021, Antioxidants.

Oxidative Stress, Bone Marrow Failure, and Genome Instability in Hematopoietic Stem Cells

C. Richardson, Shan Yan, C. G. Vestal, 2015, International journal of molecular sciences.

Function and molecular mechanisms of APE2 in genome and epigenome integrity.

A. Mcmahon, Shan Yan, Jianjun Zhao, 2021, Mutation research.

SEC-induced activation of ANXA7 GTPase suppresses prostate cancer metastasis.

Shuyan Liu, Baoxiang Zhao, L. Su, 2018, Cancer letters.

Study of the DNA damage checkpoint using Xenopus egg extracts.

Shan Yan, Y. Patel, D. Destephanis, 2012, Journal of visualized experiments : JoVE.

A non-canonical role for the DNA glycosylase NEIL3 in suppressing APE1 endonuclease-mediated ssDNA damage

Shan Yan, Yunfeng Lin, Anh Ha, 2020, The Journal of Biological Chemistry.

Correlation of Expression of Human Arrest-Defective-1 (hARD1) Protein With Breast Cancer

Min Yu, Hui Yang, Shan Yan, 2009, Cancer investigation.

An introduction for the special issue on environmental health and genome integrity.

C. Vaziri, Shan Yan, 2020, Environmental and molecular mutagenesis.

Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress

Shan Yan, Zachary Berman, Melanie S Sorrell, 2014, Cellular and Molecular Life Sciences.

APE1 recruits ATRIP to ssDNA in an RPA-dependent and -independent manner to promote the ATR DNA damage response

Shan Yan, Yunfeng Lin, Jia Li, 2023, eLife.

Molecular mechanisms of nucleolar DNA damage checkpoint response.

Shan Yan, Jia Li, 2023, Trends in cell biology.