V. Venglovecz

发表

Bile accelerates carcinogenic processes in pancreatic ductal adenocarcinoma cells through the overexpression of MUC4

P. Hegyi, L. Czakó, L. Kemény, 2020, Scientific Reports.

OEsophageal Ion Transport Mechanisms and Significance Under Pathological Conditions

P. Hegyi, B. Erőss, E. Becskeházi, 2020, Frontiers in Physiology.

Role of ion transporters in the bile acid-induced esophageal injury.

P. Hegyi, Z. Rakonczay, T. Wittmann, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis.

M. Zaccolo, G. Lukács, J. Mayerle, 2015, Gastroenterology.

Characterization of Na+-K+-2Cl− Cotransporter Activity in Rabbit Lacrimal Gland Duct Cells

P. Hegyi, Z. Rakonczay, C. Ding, 2016, Investigative ophthalmology & visual science.

Experimental evidence of fluid secretion of rabbit lacrimal gland duct epithelium.

Lukács J. Németh, P. Hegyi, Z. Rakonczay, 2014, Investigative ophthalmology & visual science.

Potassium channels in pancreatic duct epithelial cells: their role, function and pathophysiological relevance

P. Hegyi, Z. Rakonczay, V. Venglovecz, 2014, Pflügers Archiv - European Journal of Physiology.

Evidence for diagnosis of early chronic pancreatitis after three episodes of acute pancreatitis: a cross-sectional multicentre international study with experimental animal model

P. Hegyi, V. Sallinen, M. Papp, 2021, Scientific Reports.

Calcium imaging in intact mouse acinar cells in acute pancreas tissue slices

M. Gosak, S. Potrč, A. Stožer, 2022, PloS one.

Critical thresholds: key to unlocking the door to the prevention and specific treatments for acute pancreatitis

D. Yadav, P. Hegyi, R. Sutton, 2020, Gut.

Na+/Ca2+ exchangers regulate the migration and proliferation of human gastric myofibroblasts.

P. Hegyi, Z. Rakonczay, T. Wittmann, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Hyperlipidemia induced by a cholesterol-rich diet aggravates necrotizing pancreatitis in rats.

I. Boros, P. Hegyi, Z. Rakonczay, 2007, European journal of pharmacology.

A Novel in situ Approach to Studying Pancreatic Ducts in Mice

A. Stožer, J. Dolenšek, E. Gál, 2019, Front. Physiol..

Bile acids inhibit Na+/H+ exchanger and Cl−/HCO3− exchanger activities via cellular energy breakdown and Ca2+ overload in human colonic crypts

P. Hegyi, Z. Rakonczay, K. Farkas, 2014, Pflügers Archiv - European Journal of Physiology.

The Role of Pancreatic Ductal Secretion in Protection Against Acute Pancreatitis in Mice*

P. Hegyi, Z. Rakonczay, T. Wittmann, 2014, Critical care medicine.

Molecular and Cellular Mechanisms of Disease

P. Hegyi, Z. Rakonczay, J. Maléth, 2022 .

Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells

P. Hegyi, Z. Rakonczay, J. Maléth, 2010, Gut.

CFTR Expression But Not Cl− Transport Is Involved in the Stimulatory Effect of Bile Acids on Apical Cl−/HCO3− Exchange Activity in Human Pancreatic Duct Cells

P. Hegyi, Z. Rakonczay, M. Hasegawa, 2009, Pancreas.

Inhibition of Arginase Activity Ameliorates L-Arginine-Induced Acute Pancreatitis in Rats

P. Hegyi, Z. Rakonczay, T. Wittmann, 2009, Pancreas.

Cardiac electrophysiological remodeling associated with enhanced arrhythmia susceptibility in a canine model of elite exercise

P. Hegyi, N. Nagy, G. Ágoston, 2022, bioRxiv.

Novel mitochondrial transition pore inhibitor N-methyl-4-isoleucine cyclosporin is a new therapeutic option in acute pancreatitis

P. Hegyi, L. Tretter, J. Maléth, 2020 .

Novel mitochondrial transition pore inhibitor N‐methyl‐4‐isoleucine cyclosporin is a new therapeutic option in acute pancreatitis

P. Hegyi, Z. Rakonczay, L. Tretter, 2019, The Journal of physiology.

IMPORTANT THERAPEUTIC TARGETS IN ACUTE PANCREATITIS

L. Puskás, J. Mayerle, M. Lerch, 2019 .

Fentanyl but Not Morphine or Buprenorphine Improves the Severity of Necrotizing Acute Pancreatitis in Rats

P. Hegyi, Z. Rakonczay, B. Tóth, 2022, International journal of molecular sciences.

Mislocalization of CFTR expression in acute pancreatitis and the beneficial effect of VX‐661 + VX‐770 treatment on disease severity

P. Hegyi, Z. Rakonczay, J. Maléth, 2021, The Journal of physiology.

Recent advances in the investigation of pancreatic inflammation induced by large doses of basic amino acids in rodents

P. Hegyi, Z. Rakonczay, B. Iványi, 2014, Laboratory Investigation.

Characterization of Polyamine Homeostasis in l-Ornithine-Induced Acute Pancreatitis in Rats

L. Alhonen, P. Hegyi, Z. Rakonczay, 2010, Pancreas.

Pathophysiological relevance of apical large-conductance Ca2+-activated potassium channels in pancreatic duct epithelial cells

P. Hegyi, Z. Rakonczay, M. Grunnet, 2010, Gut.

Online Laboratory Investigations

P. Hegyi, Z. Rakonczay, T. Wittmann, 2014 .

Bile acid‐ and ethanol‐mediated activation of Orai1 damages pancreatic ductal secretion in acute pancreatitis

T. Crul, P. Hegyi, Á. Varga, 2022, The Journal of physiology.

Dynamic regulation of CFTR bicarbonate permeability by [Cl-]i and its role in pancreatic bicarbonate secretion.

Min Goo Lee, J. Y. Kim, H. Park, 2010, Gastroenterology.

New therapeutic targets in ulcerative colitis: The importance of ion transporters in the human colon

P. Hegyi, Z. Rakonczay, K. Farkas, 2011, Inflammatory bowel diseases.

Gastrin stimulates MMP-1 expression in gastric epithelial cells: putative role in gastric epithelial cell migration.

Z. Rakonczay, J. Kumar, G. Dockray, 2015, American journal of physiology. Gastrointestinal and liver physiology.

Ion Channels in Pancreatic Duct Epithelial Cells in Health and Disease

P. Hegyi, V. Venglovecz, M. Gray, 2021 .

New Insights into the Methodology of L-Arginine-Induced Acute Pancreatitis

P. Hegyi, Z. Rakonczay, B. Iványi, 2015, PloS one.

Identification of ezrin as a target of gastrin in immature mouse gastric parietal cells

P. Hegyi, T. Wang, G. Dockray, 2008, Experimental physiology.

Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells

I. Boros, Z. Kónya, V. Venglovecz, 2019, Journal of Nanobiotechnology.

Pancreatic Ductal Bicarbonate Secretion: Challenge of the Acinar Acid Load

P. Hegyi, Z. Rakonczay, J. Maléth, 2011, Front. Physio..

New experimental method to study acid/base transporters and their regulation in lacrimal gland ductal epithelia.

J. Papp, P. Hegyi, Z. Rakonczay, 2007, Investigative ophthalmology & visual science.

Characterization of Na+-K+-2Cl− Cotransporter Activity in Rabbit Lacrimal Gland Duct Cells

P. Hegyi, Z. Rakonczay, C. Ding, 2016, Investigative ophthalmology & visual science.

Central role of mitochondrial injury in the pathogenesis of acute pancreatitis

P. Hegyi, Z. Rakonczay, J. Maléth, 2013, Acta physiologica.

The acinar-ductal tango in the pathogenesis of acute pancreatitis

P. Hegyi, Z. Rakonczay, S. Pandol, 2010, Gut.

Galanin, a potent inhibitor of pancreatic bicarbonate secretion, is involved in the induction and progression of cerulein-induced experimental acute pancreatitis.

P. Hegyi, Z. Rakonczay, J. Maléth, 2011, Pancreas.

The crucial role of early mitochondrial injury in L-lysine-induced acute pancreatitis.

L. Alhonen, P. Hegyi, Z. Rakonczay, 2011, Antioxidants & redox signaling.

Aliphatic, but not imidazole, basic amino acids cause severe acute necrotizing pancreatitis in rats.

P. Hegyi, Z. Rakonczay, T. Wittmann, 2011, Pancreas.

The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl- Channel

L. Puskás, J. Mayerle, M. Lerch, 2018, Front. Physiol..

Pancreatitis severity in mice with impaired CFTR function but pancreatic sufficiency is mediated via ductal and inflammatory cells‐Not acinar cells

J. Mayerle, M. Lerch, J. Kühn, 2021, Journal of cellular and molecular medicine.

Trypsin reduces pancreatic ductal bicarbonate secretion by inhibiting CFTR Cl⁻ channels and luminal anion exchangers.

J. Mayerle, M. Lerch, P. Hegyi, 2011, Gastroenterology.

Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig

P. Hegyi, Z. Rakonczay, B. Ózsvári, 2008, Gut.

Kynurenic Acid and Its Analogue SZR-72 Ameliorate the Severity of Experimental Acute Necrotizing Pancreatitis

L. Vécsei, P. Hegyi, Z. Rakonczay, 2021, Frontiers in Immunology.

Substance P inhibits pancreatic ductal bicarbonate secretion via neurokinin receptors 2 and 3 in the guinea pig exocrine pancreas.

P. Hegyi, Z. Rakonczay, L. Kemény, 2011, Pancreas.

Controversies in the role of SLC26 anion exchangers in pancreatic ductal bicarbonate secretion.

P. Hegyi, Z. Rakonczay, K. Farkas, 2008, Pancreas.

Mechanisms of Post-Pancreatitis Diabetes Mellitus and Cystic Fibrosis-Related Diabetes: A Review of Preclinical Studies

L. Czakó, A. Stožer, J. Dolenšek, 2021, Frontiers in Endocrinology.

The effects of bile acids on pancreatic ductal cells

P. Hegyi, Z. Rakonczay, V. Venglovecz, 2016 .

Cigarette smoke extract inhibits fluid and HCO–3 secretion and CFTR activity in guinea pig pancreatic ductal cells

P. Hegyi, Z. Rakonczay, J. Maléth, 2014 .

Ethanol and its non-oxidative metabolites profoundly inhibit CFTR function in pancreatic epithelial cells which is prevented by ATP supplementation

P. Hegyi, V. Venglovecz, Z. Rakonczay, 2014, Pflügers Archiv - European Journal of Physiology.

NHE1 activity contributes to migration and is necessary for proliferation of human gastric myofibroblasts

P. Hegyi, Z. Rakonczay, T. Wittmann, 2012, Pflügers Archiv - European Journal of Physiology.

Efficacy and safety of stenting and additional oncological treatment versus stenting alone in unresectable esophageal cancer: a meta-analysis and systematic review.

P. Hegyi, A. Erős, A. Soós, 2020, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Inhibition of NHE-1 Increases Smoke-Induced Proliferative Activity of Barrett’s Esophageal Cell Line

P. Hegyi, Zoltán Márton Köhler, Z. Helyes, 2021, International journal of molecular sciences.

Breakdown of bioenergetics evoked by mitochondrial damage in acute pancreatitis: Mechanisms and consequences.

P. Hegyi, Z. Rakonczay, J. Maléth, 2015, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Effects of alcohol on pancreatic ductal function

P. Hegyi, Z. Rakonczay, J. Maléth, 2016 .

Effects of ethanol and ethanol metabolites on the pancreatic ductal bicarbonate secretion

P. Hegyi, Z. Rakonczay, J. Maléth, 2016 .

A novel, protective role of ursodeoxycholate in bile-induced pancreatic ductal injury.

P. Hegyi, J. Maléth, M. Katona, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Short-term CFTR inhibition reduces islet area in C57BL/6 mice

N. Irwin, M. Flodström-Tullberg, C. Kelly, 2019, Scientific Reports.

Pancreatic epithelial fluid and bicarbonate secretion is significantly elevated in the absence of peripheral serotonin

P. Hegyi, J. Maléth, A. Balázs, 2015, Gut.

Potassium channels in pancreatic duct epithelial cells: their role, function and pathophysiological relevance

P. Hegyi, Z. Rakonczay, V. Venglovecz, 2015, Pflügers Archiv - European Journal of Physiology.

Bile acids inhibit Na+/H+ exchanger and Cl−/HCO3− exchanger activities via cellular energy breakdown and Ca2+ overload in human colonic crypts

P. Hegyi, F. Nagy, T. Wittmann, 2015, Pflügers Archiv - European Journal of Physiology.

Su1249 Non-Oxidative Ethanol Metabolites Induce Intracellular ATP Depletion and Inhibit Pancreatic Ductal Bicarbonate Secretion in Human Pancreatic Ductal Epithelial Cell Line

P. Hegyi, T. Wittmann, J. Maléth, 2012 .

Breakdown of bioenergetics evoked by mitochondrial damage in acute pancreatitis: Mechanisms and consequences.

P. Hegyi, Z. Rakonczay, J. Maléth, 2015, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Dynamic regulation of CFTR bicarbonate permeability by [Cl-]i and its role in pancreatic bicarbonate secretion.

Min Goo Lee, J. Y. Kim, H. Park, 2010, Gastroenterology.

The acinar-ductal tango in the pathogenesis of acute pancreatitis

P. Hegyi, Z. Rakonczay, S. Pandol, 2010, Gut.

Role of CFTR in diabetes‐induced pancreatic ductal fluid and HCO3− secretion

E. Gál, V. Venglovecz, E. Tóth, 2024, The Journal of physiology.

GPR30 is a potential player between islet cells and ductal HCO3- secretion.

V. Venglovecz, P. Hegyi, 2024, Cell calcium.

Heavy metals in cigarette smoke strongly inhibit pancreatic ductal function and promote development of chronic pancreatitis

Z. Rakonczay, Á. Varga, J. Maléth, 2024, Clinical and translational medicine.

Investigating the influence of taurochenodeoxycholic acid (TCDCA) on pancreatic cancer cell behavior: An RNA Sequencing Approach.

E. Gál, V. Venglovecz, Shahram Parvaneh, 2024, Journal of biotechnology.