J Ren

发表

The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin.

D I Stuart, D. Stuart, J. Ren, 1994, Structure.

2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1.

D I Stuart, R J Ott, D. Stuart, 2001, Journal of medicinal chemistry.

Energetics of DNA intercalation reactions.

J. Chaires, J. Ren, T. C. Jenkins, 2000, Biochemistry.

Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor.

D I Stuart, R M Esnouf, D. Stuart, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies.

D I Stuart, R M Esnouf, D. Stuart, 1999, Journal of medicinal chemistry.

Sequence and structural selectivity of nucleic acid binding ligands.

J. Chaires, J. Ren, J B Chaires, 1999, Biochemistry.

Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase.

D I Stuart, J Milton, D. Stuart, 2000, Structure.

Alpha-lactalbumin possesses a distinct zinc binding site.

D I Stuart, D. Stuart, J. Ren, 1995, The Journal of biological chemistry.

Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.

D I Stuart, R M Esnouf, D. Stuart, 1998, Biochemistry.

Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.

D I Stuart, D. Stuart, D. Stammers, 2001, Journal of molecular biology.

DNA binding properties of the indolocarbazole antitumor drug NB-506.

W D Wilson, C. Bailly, J. Chaires, 2001, Anti-cancer drug design.

The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design.

D. Stuart, R. Esnouf, A. Hopkins, 1995, Structure.

Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants.

D I Stuart, D. Stuart, A. Hopkins, 1999, Journal of medicinal chemistry.

Binding of the Second Generation Non-nucleoside Inhibitor S-1153 to HIV-1 Reverse Transcriptase Involves Extensive Main Chain Hydrogen Bonding*

D I Stuart, D. Stammers, L. Bird, 2000, The Journal of Biological Chemistry.

Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors.

P P Chamberlain, D. Stammers, C. Nichols, 2004, Journal of molecular biology.