Lee M Greenberger

发表

Novel prodrugs of SN38 using multiarm poly(ethylene glycol) linkers.

Hong Zhao, L. Greenberger, I. Horak, 2008, Bioconjugate chemistry.

Synthesis and Structure−Activity Relationships of 6,7-Disubstituted 4-Anilinoquinoline-3-carbonitriles. The Design of an Orally Active, Irreversible Inhibitor of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor (EGFR) and the Human Epidermal Growth Factor Receptor-2 (HER-2)

Ramaswamy Nilakantan, Fei Ye, Allan Wissner, 2003 .

Cellular and in Vivo Activity of JNJ-28871063, A Nonquinazoline Pan-ErbB Kinase Inhibitor That Crosses the Blood-Brain Barrier and Displays Efficacy against Intracranial Tumors

Mary Adams, Niranjan Pandey, Terry V Hughes, 2008, Molecular Pharmacology.

Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases.

Mary Adams, Niranjan Pandey, Terry V Hughes, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and biological study of 4-aminopyrimidine-5-carboxaldehyde oximes as antiproliferative VEGFR-2 inhibitors.

S. Emanuel, P. Connolly, Shenlin Huang, 2006, Bioorganic & medicinal chemistry letters.

Marked therapeutic efficacy of a novel polyethylene glycol-SN38 conjugate, EZN-2208, in xenograft models of B-cell non-Hodgkin’s lymphoma

Patricia Kraft, Hong Zhao, L. Greenberger, 2009, Haematologica.

Role of the ABCG2 drug transporter in the resistance and oral bioavailability of a potent cyclin-dependent kinase/Aurora kinase inhibitor

A. Calcagno, S. Ambudkar, S. Emanuel, 2006, Molecular Cancer Therapeutics.

Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles.

Ramaswamy Nilakantan, Frank Loganzo, Fei Ye, 2004, Bioorganic & medicinal chemistry letters.

An anti-MUC1 antibody-calicheamicin conjugate for treatment of solid tumors. Choice of linker and overcoming drug resistance.

Ana T Menendez, L. Greenberger, F. Durr, 2005, Bioconjugate chemistry.

Preclinical Pharmacologic Evaluation of MST-997, an Orally Active Taxane with Superior In vitro and In vivo Efficacy in Paclitaxel- and Docetaxel-Resistant Tumor Models

Deepak Sampath, Carol Rios, D. Sampath, 2006, Clinical Cancer Research.