S. Tonomura

发表

Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N2-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl++ +) sulfonyl]-l-arginyl)]-2-piperidinecarboxylic acid.

R. Kikumoto, Y. Tamao, T. Tezuka, 1984, Biochemistry.

THROMBIN INHIBITORS. 1. ESTER DERIVATIVES OF Nα-(ARYLSULFONYL)-L-ARGININE

R. Kikumoto, Y. Tamao, S. Tonomura, 1981 .

Thrombin inhibitors. 1. Ester derivatives of N alpha-(arylsulfonyl)-L-arginine.

R. Kikumoto, Y. Tamao, S. Tonomura, 1980, Journal of medicinal chemistry.

Thrombin inhibitors. 2. Amide derivatives of N alpha-substituted L-arginine.

T. Tezuka, R. Kikumoto, Y. Tamao, 1980, Journal of medicinal chemistry.

Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion.

R. Kikumoto, Y. Tamao, S. Tonomura, 1981, Biochemical and biophysical research communications.

Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N alpha-substituted L-arginine.

T. Tezuka, R. Kikumoto, Y. Tamao, 1980, Journal of medicinal chemistry.

Pharmacokinetic Studies of Argipidine (MD-805) in Rats (I): In vivo and in vitro metabolism of argipidine

S. Iida, T. Komatsu, R. Kikumoto, 1986 .

Similarity and dissimilarity in the stereogeometry of the active sites of thrombin, trypsin, plasmin and glandular kallikrein.

O. Matsumoto, R. Kikumoto, Y. Tamao, 1987, Thrombosis research.

SYNTHESIS AND ANTIDEPRESSANT ACTIVITY OF SUBSTITUTED (Ω-AMINOALKOXY)BENZENE DERIVATIVES

R. Kikumoto, S. Tonomura, A. Tobe, 1981 .

Synthesis and antidepressant activity of substituted (omega-aminoalkoxy)benzene derivatives.

R. Kikumoto, S. Tonomura, A. Tobe, 1981, Journal of medicinal chemistry.

Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCI-2016), a new psychotropic drug with antidepressant activity.

R. Kikumoto, S. Tonomura, A. Tobe, 1981, Arzneimittel-Forschung.

THROMBIN INHIBITORS. 3. CARBOXYL-CONTAINING AMIDE DERIVATIVES OF Nα-SUBSTITUTED L-ARGININE

Y. Hijikata, T. Tezuka, R. Kikumoto, 1981 .

THROMBIN INHIBITORS. 2. AMIDE DERIVATIVES OF Nα-SUBSTITUTED L-ARGININE

T. Tezuka, R. Kikumoto, Y. Tamao, 1981 .

Structure-activity relationship in a series of synthetic thrombin inhibitors: No. 205, No. 407 and No. 700

T. Tezuka, R. Kikumoto, Y. Tamao, 1980 .