J. Rausch

发表

Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3' polypurine tract.

S. L. Le Grice, C. Dash, J. Rausch, 2004, Nucleic acids research.

Dynamic binding orientations direct activity of HIV reverse transcriptase

Elio A. Abbondanzieri, Xiaowei Zhuang, X. Zhuang, 2008, Nature.

RNA secondary structure prediction using high-throughput SHAPE.

Katarzyna J Purzycka, K. Purzycka, S. L. Le Grice, 2013, Journal of visualized experiments : JoVE.

Using SHAPE-MaP to probe small molecule-RNA interactions.

S. Martin, Joanna Sztuba-Solinska, J. Rausch, 2019, Methods.

Characterization of (+) strand initiation and termination sequences located at the center of the equine infectious anemia virus genome.

M. Waring, S. L. Le Grice, L. Boone, 1999, Biochemistry.

Structural characterization of maternally expressed gene 3 RNA reveals conserved motifs and potential sites of interaction with polycomb repressive complex 2

Chringma Sherpa, J. Rausch, Stuart F J Le Grice, 2018, Nucleic acids research.

APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R

Patrick D. Dummer, C. Winkler, S. Hewitt, 2018, Communications Biology.

Dissecting APOBEC3G Substrate Specificity by Nucleoside Analog Interference*

S. L. Le Grice, M. Goodman, J. Rausch, 2009, Journal of Biological Chemistry.

Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors

Michele D. Sobolewski, Wei-Shau Hu, S. Hughes, 2019, Proceedings of the National Academy of Sciences.

Probing the Structures of Viral RNA Regulatory Elements with SHAPE and Related Methodologies

S. L. Le Grice, Joanna Sztuba-Solinska, J. Rausch, 2018, Front. Microbiol..

Reverse Transcription in the Saccharomyces cerevisiae Long-Terminal Repeat Retrotransposon Ty3

S. L. Le Grice, Jennifer T. Miller, J. Rausch, 2017, Viruses.

Ribonuclease H Inhibitors: Structural and Molecular Biology

J. Rausch, 2013 .

Exploiting structurally diverse nucleoside analogs as probes of reverse transcription complexes.

S. L. Le Grice, J. Rausch, 2007, Current HIV research.

Probing Contacts between the Ribonuclease H Domain of HIV-1 Reverse Transcriptase and Nucleic Acid by Site-specific Photocross-linking*

B. Sathyanarayana, S. L. Le Grice, Marion K. Bona, 2000, The Journal of Biological Chemistry.

Interaction of p55 Reverse Transcriptase from theSaccharomyces cerevisiae Retrotransposon Ty3 with Conformationally Distinct Nucleic Acid Duplexes*

S. L. Le Grice, Jennifer T. Miller, J. Rausch, 2000, The Journal of Biological Chemistry.

HIV-1 reverse transcriptase interaction with model RNA-DNA duplexes.

S. L. Le Grice, I. Gorshkova, R. Crouch, 2001, Analytical biochemistry.

HIV-1 reverse transcriptase can simultaneously engage its DNA/RNA substrate at both DNA polymerase and RNase H active sites: implications for RNase H inhibition.

M. Wendeler, S. L. Le Grice, G. Beilhartz, 2009, Journal of molecular biology.

Evaluation of retroviral ribonuclease H activity.

S. L. Le Grice, J. Miller, J. Rausch, 2001, Methods in molecular biology.

Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA

J. Mellors, B. Luke, J. Coffin, 2016, Retrovirology.

Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection

S. L. Le Grice, E. Kool, J. Rausch, 2003, Proceedings of the National Academy of Sciences of the United States of America.

SiRNA-Induced Mutation in HIV-1 Polypurine Tract Region and Its Influence on Viral Fitness

Kendall C. Krebs, Chuanwu Zhu, Yong Gao, 2015, PloS one.

Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions.

S. Sarafianos, S. L. Le Grice, B. Marchand, 2010, Biochimica et biophysica acta.

Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands

Robert G. Brinson, Kevin B. Turner, S. L. Le Grice, 2008, Nucleic acids research.

Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis

S. L. Le Grice, J. Rausch, 2006, Nucleic acids research.

'Binding, bending and bonding': polypurine tract-primed initiation of plus-strand DNA synthesis in human immunodeficiency virus.

S. L. Le Grice, J. Rausch, 2004, The international journal of biochemistry & cell biology.

Altering the RNase H primer grip of human immunodeficiency virus reverse transcriptase modifies cleavage specificity.

S. Hughes, S. L. Le Grice, Jennifer T. Miller, 2002, Biochemistry.

Substituting a Conserved Residue of the Ribonuclease H Domain Alters Substrate Hydrolysis by Retroviral Reverse Transcriptase*

S. L. Le Grice, J. Rausch, Stuart F. J. Le Grice, 1997, The Journal of Biological Chemistry.

Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase.

C. Cameron, S. Benkovic, S. L. Le Grice, 1995, Biochemistry.

Exploiting drug-resistant enzymes as tools to identify thienopyrimidinone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.

P. Caboni, S. L. Le Grice, J. Beutler, 2013, Journal of medicinal chemistry.

Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.

E. Arnold, S. L. Le Grice, D. Himmel, 2011, Journal of medicinal chemistry.

Retrovirus Replication: New Perspectives on Enzyme and Substrate Dynamics

X. Zhuang, E. Abbondanzieri, S. F. Grice, 2010 .

Slide into Action: Dynamic Shuttling of HIV Reverse Transcriptase on Nucleic Acid Substrates

Elio A. Abbondanzieri, Xiaowei Zhuang, Shixin Liu, 2008, Science.

Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H

X. Zhuang, M. Wendeler, S. L. Le Grice, 2010, Antimicrobial Agents and Chemotherapy.

Interplay of primary sequence, position and secondary RNA structure determines alternative splicing of LMNA in a pre-mature aging syndrome.

T. Misteli, S. L. Le Grice, Asaf Shilo, 2019, Nucleic acids research.

Interplay of primary sequence and RNA secondary structure in determining 5′ splice site choice

T. Misteli, S. L. Le Grice, Asaf Shilo, 2018 .

CpG Methylation Profiles of HIV-1 Proviral DNA in Individuals on ART

J. Coffin, B. Keele, S. Deeks, 2021, Viruses.

The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication

S. L. Le Grice, D. Rekosh, M. Hammarskjold, 2015, Nucleic acids research.

An Unusual Topological Structure of the HIV-1 Rev Response Element

J. Kjems, C. Schwieters, Yun-Xing Wang, 2013, Cell.

Low genetic diversity may be an Achilles heel of SARS-CoV-2

M. Kearney, Mary F. Kearney, J. Rausch, 2020, Proceedings of the National Academy of Sciences.

Characterizing the Latent HIV-1 Reservoir in Patients with Viremia Suppressed on cART: Progress, Challenges, and Opportunities

S. L. Le Grice, J. Rausch, Stuart F.J. Le Grice, 2019, Current HIV research.

A Pre-Vaccination Baseline of SARS-CoV-2 Genetic Surveillance and Diversity in the United States

J. Coffin, M. Kearney, Mary F. Kearney, 2022, Viruses.

2020 SARS-CoV-2 diversification in the United States: Establishing a pre-vaccination baseline

J. Coffin, W. Shao, M. Kearney, 2021, medRxiv.

Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA

J. Mellors, J. Coffin, F. Maldarelli, 2016, Retrovirology.

HIV-1 Viremia Not Suppressible By Antiretroviral Therapy Can Originate from Large T-Cell Clones Producing Infectious Virus

S. Hughes, J. Mellors, J. Coffin, 2020, bioRxiv.

Deep Sequencing Analysis of Individual HIV-1 Proviruses Reveals Frequent Asymmetric Long Terminal Repeats

S. Mallal, J. Mellors, J. Coffin, 2022, Journal of virology.

Targeting HIV-1 Reverse Transcriptase : a Coat with Many Pockets

Suhman Chung, J. Rausch, 2022 .

Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA: a structural scaffold for nuclear, cytoplasmic and viral proteins

S. L. Le Grice, Jennifer T. Miller, Joanna Sztuba-Solinska, 2017, Nucleic acids research.

HIV-1 Transmission by Dendritic Cell-specific ICAM-3-grabbing Nonintegrin (DC-SIGN) Is Regulated by Determinants in the Carbohydrate Recognition Domain That Are Absent in Liver/Lymph Node-SIGN (L-SIGN)*

S. L. Le Grice, V. KewalRamani, J. Rausch, 2009, The Journal of Biological Chemistry.

Characterizing and circumventing sequence restrictions for synthesis of circular RNA in vitro.

M. Gorospe, W. Heinz, Chringma Sherpa, 2021, Nucleic acids research.

APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R

Patrick D. Dummer, C. Winkler, S. Hewitt, 2018, Communications Biology.

Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid

J. Bujnicki, D. Svergun, S. L. Le Grice, 2013, Nucleic acids research.

Mutations in the ribonuclease H active site of HIV-RT reveal a role for this site in stabilizing enzyme-primer-template binding.

J. DeStefano, S. L. Le Grice, J. Rausch, 2002, Biochemistry.

Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs: implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases.

M. Wainberg, R. Goody, E. Arts, 1996, Proceedings of the National Academy of Sciences of the United States of America.

HIV Rev Assembly on the Rev Response Element (RRE): A Structural Perspective

S. L. Le Grice, Stuart F. J. Le Grice, J. Rausch, 2015, Viruses.

HIV Genetic Diversity - Superpower of a Formidable Virus.

S. L. Le Grice, Chringma Sherpa, J. Rausch, 2020, Current HIV research.

The HIV-2 Rev-response element: determining secondary structure and defining folding intermediates

Katarzyna J Purzycka, Joanna Sztuba-Solinska, S. F. Grice, 2013, Nucleic acids research.

Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome

B. Shapiro, S. L. Le Grice, Joanna Sztuba-Solinska, 2013, Nucleic acids research.

HIV Expression in Infected T Cell Clones

Mary F. Kearney, J. Rausch, A. Capoferri, 2024, Viruses.