Madhavi N L Nalam

Extreme entropy-enthalpy compensation in a drug-resistant variant of HIV-1 protease.

Celia A Schiffer, C. Schiffer, Ayşegül Özen, 2012, ACS chemical biology.

Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease.

Celia A Schiffer, Yufeng Cai, C. Schiffer, 2012, Journal of the American Chemical Society.

Design of Mutation‐resistant HIV Protease Inhibitors with the Substrate Envelope Hypothesis

Hong Cao, Bruce Tidor, Michael K Gilson, 2007, Chemical biology & drug design.

Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance.

Hong Cao, Bruce Tidor, Nese Kurt Yilmaz, 2013, Chemistry & biology.

Design and synthesis of HIV-1 protease inhibitors incorporating oxazolidinones as P2/P2' ligands in pseudosymmetric dipeptide isosteres.

Akbar Ali, Celia A Schiffer, Tariq M Rana, 2007, Journal of medicinal chemistry.

Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands.

Akbar Ali, Celia A Schiffer, Tariq M Rana, 2006, Journal of medicinal chemistry.

HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants.

Hong Cao, Bruce Tidor, Michael K Gilson, 2008, Journal of the American Chemical Society.

Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones.

Akbar Ali, Celia A Schiffer, Tariq M Rana, 2010, Journal of medicinal chemistry.