P C Isakson

Characterization of a monoclonal antibody that neutralizes the activity of prostaglandin E2.

P. Isakson, A. W. Veenhuizen, J. Monahan, 1995, Journal of immunology.

Novel terphenyls as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.

C. Koboldt, K. Seibert, P. Isakson, 1996, Journal of medicinal chemistry.

Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.

P. Isakson, S. Gregory, G. Anderson, 1996, The Journal of clinical investigation.

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

K. Seibert, P. Isakson, J. Masferrer, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

K. Seibert, P. Isakson, J. Masferrer, 1996, The Journal of experimental medicine.

1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2.

C. Koboldt, K. Seibert, P. Isakson, 1997, Journal of medicinal chemistry.

Diarylspiro[2.4]heptenes as orally active, highly selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationships.

C. Koboldt, K. Seibert, P. Isakson, 1996, Journal of medicinal chemistry.

1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.

C. Koboldt, P. Isakson, S. Gregory, 1995, Journal of medicinal chemistry.