E. Gabano

发表

Studies on Log Po/w of Quinoxaline di-N-Oxides: A Comparison of RP-HPLC Experimental and Predictive Approaches

J. Platts, A. Monge, E. Moreno, 2011, Molecules.

195Pt NMR spectroscopy: A chemometric approach

M. Botta, D. Osella, E. Marengo, 2006 .

Functionalized nonporous silica nanoparticles as carriers for Pt(iv) anticancer prodrugs.

I. Zanellato, D. Osella, E. Gabano, 2016, Dalton transactions.

Synthesis of PtIV‐Biomolecule Conjugates through Click Chemistry

D. Osella, E. Gabano, M. Ravera, 2015 .

Synthesis and characterization of cyclohexane-1R,2R-diamine-based Pt(iv) dicarboxylato anticancer prodrugs: their selective activity against human colon cancer cell lines.

I. Zanellato, D. Osella, E. Gabano, 2019, Dalton transactions.

An unsymmetric cisplatin-based Pt(iv) derivative containing 2-(2-propynyl)octanoate: a very efficient multi-action antitumor prodrug candidate.

I. Zanellato, D. Osella, V. Gandin, 2017, Dalton transactions.

Cisplatin and valproate released from the bifunctional [Pt(IV)Cl2(NH3)2(valproato)2] antitumor prodrug or from liposome formulations: who does what?

I. Zanellato, D. Osella, A. Gallina, 2017, Dalton transactions.

Application of microwave-assisted heating to the synthesis of Pt(II) complexes

E. Gabano, M. Ravera, F. Mendes, 2015 .

Electrochemical Biosensor Assay of the Interaction between [PtCln(NH3)4–n](2–n) (n = 0–4) Complexes and ds-DNA†

D. Osella, E. Gabano, M. Ravera, 2011 .

Electrochemical evaluation of the interaction between antitumoral titanocene dichloride and biomolecules

D. Osella, E. Gabano, M. Ravera, 2009 .

Trend in cytotoxic activity of a series of cis-[APtCl2] (A = ethylenediamine methylated at different positions) complexes

E. Monti, D. Osella, M. Gariboldi, 2008 .

Conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition

E. Gabano, M. Ravera, E. Perin, 2019, Inorganica Chimica Acta.

The hexacarbonyldicobalt derivative of aspirin acts as a CO-releasing NSAID on malignant mesothelioma cells.

I. Zanellato, D. Osella, R. Gust, 2013, Metallomics : integrated biometal science.

Electrochemical studies of a series of antimetastatic mono- and di-ruthenium complexes [Na][trans-RuIIICl4(DMSO)(L)] and [Na]2[{trans-RuIIICl4(DMSO)}2(μ-L)] (L = N-donor heterocyclic bridging ligand)

D. Osella, E. Gabano, M. Ravera, 2008 .

The Relevance of Polar Surface Area (PSA) in Rationalizing Biological Properties of Several cis‐Diamminemalonatoplatinum(II) Derivatives

E. Monti, D. Osella, M. Gariboldi, 2009, ChemMedChem.

Organometallic compounds in the discovery of new agents against kinetoplastid-caused diseases.

E. Gabano, M. Ravera, S. Pérez-Silanes, 2018, European journal of medicinal chemistry.

Polyanionic Biopolymers for the Delivery of Pt(II) Cationic Antiproliferative Complexes

I. Zanellato, D. Osella, E. Gabano, 2016, Bioinorganic chemistry and applications.

Hybrid inorganic (nonporous silica)/organic (alginate) core-shell platform for targeting a cisplatin-based Pt(IV) anticancer prodrug.

I. Zanellato, D. Osella, M. Biggiogera, 2018, Journal of inorganic biochemistry.

Stepwise assembly of platinum–folic acid conjugates

D. Osella, G. Palmisano, C. Cassino, 2008 .

trans,cis,cis‐Bis(benzoato)dichlorido(cyclohexane‐1R,2R‐diamine)platinum(IV): a Prodrug Candidate for the Treatment of Oxaliplatin‐Refractory Colorectal Cancer

D. Osella, V. Gandin, C. Marzano, 2014, ChemMedChem.

Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands.

E. Monti, D. Osella, M. Gariboldi, 2011, Journal of inorganic biochemistry.

Molecular interaction fields vs. quantum-mechanical-based descriptors in the modelling of lipophilicity of platinum(IV) complexes.

J. Platts, D. Osella, G. Caron, 2013, Dalton transactions.

Antiproliferative activity of a series of cisplatin-based Pt(IV)-acetylamido/carboxylato prodrugs.

J. Platts, I. Zanellato, D. Osella, 2016, Dalton transactions.

Pros and cons of bifunctional platinum(IV) antitumor prodrugs: two are (not always) better than one.

D. Osella, E. Gabano, M. Ravera, 2014, Dalton transactions.

Microwave-Assisted Synthesis: Can Transition Metal Complexes Take Advantage of This “Green” Method?

E. Gabano, M. Ravera, 2022, Molecules.

Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure–activity relationship modeling

P. Gramatica, E. Monti, D. Osella, 2010, JBIC Journal of Biological Inorganic Chemistry.

Poly(methylmetacrylate) (PMMA) core–shell nanospheres act as efficient pharmacophores for the antiproliferative [PtCl3(NH3)]− complex by forming ionic couples

E. Monti, D. Osella, M. Gariboldi, 2009 .

Functional fluorescent nonporous silica nanoparticles as carriers for Pt(IV) anticancer prodrugs.

I. Zanellato, D. Osella, K. Sparnacci, 2015, Journal of inorganic biochemistry.

Unprecedented one-pot synthesis of an unsymmetrical cisplatin-based Pt(IV)-acetamidato complex.

D. Osella, G. Pelosi, E. Gabano, 2015, Chemical communications.

Biological activity of a series of cisplatin-based aliphatic bis(carboxylato) Pt(IV) prodrugs: how long the organic chain should be?

I. Zanellato, D. Osella, D. Colangelo, 2014, Journal of inorganic biochemistry.

Anthracene-terpyridine metal complexes as new G-quadruplex DNA binders.

R. Vilar, E. Gabano, M. Ravera, 2016, Journal of inorganic biochemistry.

Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on malignant pleural mesothelioma cells.

I. Zanellato, D. Osella, E. Gabano, 2013, Journal of inorganic biochemistry.

A new entry to asymmetric platinum(IV) complexes via oxidative chlorination.

D. Osella, G. Pelosi, E. Gabano, 2014, Inorganic chemistry.

Pt(IV) Bifunctional Prodrug Containing 2-(2-Propynyl)octanoato Axial Ligand: Induction of Immunogenic Cell Death on Colon Cancer.

I. Zanellato, D. Osella, E. Gabano, 2019, Journal of medicinal chemistry.

Evaluation of Platinum–Ethacrynic Acid Conjugates in the Treatment of Mesothelioma

I. Zanellato, D. Osella, E. Gabano, 2011, ChemMedChem.

Image-Guided Nanodelivery of Pt(IV) Prodrugs to GRP-Receptor Positive Tumors

T. Pinheiro, E. Gabano, M. Ravera, 2023, Nanotheranostics.

Can the Self-Assembling of Dicarboxylate Pt(IV) Prodrugs Influence Their Cell Uptake?

D. Osella, E. Gabano, M. Ravera, 2021, Bioinorganic chemistry and applications.

Electrostatic Interaction of Negatively Charged Core–Shell Nanoparticles with Antitumoral Cationic Platinum‐Based Complexes

D. Osella, K. Sparnacci, M. Laus, 2011 .

Unsymmetric Cisplatin-Based Pt(IV) Conjugates Containing a PARP-1 Inhibitor Pharmacophore Tested on Malignant Pleural Mesothelioma Cell Lines

D. Osella, L. Moro, G. Pinton, 2021, Molecules.

Pt(IV)/Re(I) Chitosan Conjugates as a Flexible Platform for the Transport of Therapeutic and/or Diagnostic Anticancer Agents

E. Gabano, M. Ravera, E. Perin, 2017 .

Synthesis, characterization and antiproliferative activity on mesothelioma cell lines of bis(carboxylato)platinum(IV) complexes based on picoplatin.

I. Zanellato, D. Osella, V. Moreno, 2012, Dalton transactions.

Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural characterization and biological studies.

I. Santos, E. Gabano, M. Ravera, 2011, Dalton transactions.

Biological activity of enantiomeric complexes [PtCl2L2] (L2 is aromatic bisphosphanes and aromatic diamines)

E. Monti, D. Osella, M. Gariboldi, 2010, JBIC Journal of Biological Inorganic Chemistry.

The power of a novel combined anticancer therapy: challenge and opportunity of micotherapy in the treatment of Glioblastoma Multiforme.

M. Bottone, P. Rossi, E. Roda, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs.

G. Natile, I. Zanellato, D. Osella, 2015, Journal of inorganic biochemistry.

Synthesis and characterisation of estrogenic carriers for cytotoxic Pt(II) fragments: biological activity of the resulting complexes.

D. Osella, D. Colangelo, C. Prandi, 2005, Organic & biomolecular chemistry.

Platinum(II) and technetium(I) complexes anchored to ethynylestradiol: a way to drug targeting and delivery

D. Osella, A. Vessières, G. Jaouen, 2004 .

Metallo-drugs in the treatment of malignant pleural mesothelioma

N. Margiotta, I. Zanellato, P. Betta, 2012 .

Revisiting [PtCl₂(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer.

J. Platts, N. Margiotta, G. Natile, 2012, Journal of medicinal chemistry.

The RP-HPLC measurement and QSPR analysis of logP(o/w) values of several Pt(II) complexes.

Domenico Osella, James A Platts, Maria M. Reif, 2006, Journal of inorganic biochemistry.

Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).

D. Osella, M. Aceto, C. Cassino, 2004, Journal of inorganic biochemistry.

Synthesis and Biological Studies of Pyrazolyl‐Diamine PtII Complexes Containing Polyaromatic DNA‐Binding Groups

J. Rino, I. Santos, E. Gabano, 2012, Chembiochem : a European journal of chemical biology.

How to obtain Pt(iv) complexes suitable for conjugation to nanovectors from the oxidation of [PtCl(terpyridine)].

J. Platts, A. Gallina, E. Gabano, 2017, Dalton transactions.

Freshening up Old Methods for New Students: A Colorful Laboratory Experiment to Measure the Formation Constants of Ni(II) Complexes Containing Ethane-1,2-Diamine

E. Gabano, M. Ravera, A. Nucera, 2022, Journal of Chemical Education.

Corrigendum: Can an Elusive Platinum(III) Oxidation State be Exposed in an Isolated Complex?

D. Osella, M. Crestoni, S. Fornarini, 2022, Angewandte Chemie.

Host–guest inclusion systems of Pt(IV)-bis(benzoato) anticancer drug candidates and cyclodextrins

I. Zanellato, D. Osella, G. Caron, 2015 .

A view on multi-action Pt(IV) antitumor prodrugs

D. Osella, E. Gabano, M. Ravera, 2019, Inorganica Chimica Acta.

Transition metal carbonyl clusters in biology: A futile or niche research area?

D. Osella, E. Gabano, M. Ravera, 2018 .

A Comparative Study of the Effects of Platinum (II) Complexes on β-Amyloid Aggregation: Potential Neurodrug Applications

I. Iacobucci, M. Monti, D. Marasco, 2021, International journal of molecular sciences.

Cis,cis,trans-[PtIVCl2(NH3)2(perillato)2], a dual-action prodrug with excellent cytotoxic and antimetastatic activity.

I. Zanellato, D. Osella, M. Bottone, 2021, Dalton transactions.

Antiproliferative Activity of Pt(IV) Conjugates Containing the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Ketoprofen and Naproxen †

I. Zanellato, D. Osella, E. Gabano, 2019, International journal of molecular sciences.

The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions.

I. Zanellato, E. Monti, D. Osella, 2018, Dalton transactions.

Role of Metal Ions in Dopamine Oxidation

E. Gabano, M. Ravera, 2021, Journal of Chemical Education.

The drug targeting and delivery approach applied to pt-antitumour complexes. A coordination point of view.

D. Osella, E. Gabano, M. Ravera, 2009, Current medicinal chemistry.

HPLC method for the determination of monomer conversion and composition during the poly(styrene-r-methylmethacrylate) polymerization

K. Sparnacci, M. Laus, V. Gianotti, 2020 .

Elusive Intermediates in the Breakdown Reactivity Patterns of Prodrug Platinum(IV) Complexes

N. Russo, D. Osella, M. Crestoni, 2019, Journal of The American Society for Mass Spectrometry.

Functionalized thymidine derivatives as carriers for the γ-emitter technetium tricarbonyl moiety

D. Osella, R. Alberto, C. Cassino, 2009 .

The Strange Case: The Unsymmetric Cisplatin-Based Pt(IV) Prodrug [Pt(CH3COO)Cl2(NH3)2(OH)] Exhibits Higher Cytotoxic Activity with respect to Its Symmetric Congeners due to Carrier-Mediated Cellular Uptake

I. Zanellato, D. Osella, L. Moro, 2022, Bioinorganic chemistry and applications.

Prediction of logP for Pt(II) and Pt(IV) complexes: Comparison of statistical and quantum-chemistry based approaches.

Igor V Tetko, Mauro Ravera, James A Platts, 2016, Journal of inorganic biochemistry.

Antiproliferative Activity of PtII Complexes with Carboxylated Phosphanes in Chelated or Ring‐Opened Forms

E. Monti, D. Osella, M. Gariboldi, 2012 .

Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum(IV) complexes

J. Platts, D. Osella, G. Caron, 2011, JBIC Journal of Biological Inorganic Chemistry.

Solvolysis of a series of cisplatin-like complexes - comparison between DNA-biosensor and conductivity data

J. Platts, D. Osella, E. Gabano, 2012 .

Study of the synthesis, antiproliferative properties, and interaction with DNA and polynucleotides of cisplatin-like Pt(II) complexes containing carcinogenic polyaromatic amines

E. Monti, M. Gariboldi, S. Bombard, 2013, JBIC Journal of Biological Inorganic Chemistry.

May glutamine addiction drive the delivery of antitumor cisplatin-based Pt(IV) prodrugs?

I. Zanellato, D. Osella, E. Gabano, 2017, Journal of inorganic biochemistry.

Pt(IV) antitumor prodrugs: dogmas, paradigms, and realities

D. Osella, E. Gabano, M. Ravera, 2022, Dalton Transactions.

A multi-methodological inquiry of the behavior of cisplatin-based Pt(IV) derivatives in the presence of bioreductants with a focus on the isolated encounter complexes

D. Osella, M. Crestoni, S. Fornarini, 2020, JBIC Journal of Biological Inorganic Chemistry.

Bioinorganic Chemistry: The Study of the Fate of Platinum-Based Antitumour Drugs

D. Osella, D. Colangelo, E. Gabano, 2007 .

Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach.

Elena Monti, Emilio Marengo, Domenico Osella, 2005, Journal of medicinal chemistry.

Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line.

E. Monti, D. Osella, M. Gariboldi, 2007, Cancer letters.

Pt(IV) complexes based on cyclohexanediamines and the histone deacetylase inhibitor 2-(2-propynyl)octanoic acid: synthesis, characterization, cell penetration properties and antitumor activity.

N. Margiotta, V. Gandin, G. Caron, 2021, Dalton transactions.

A step towards development of promising trypanocidal agents: Synthesis, characterization and in vitro biological evaluation of ferrocenyl Mannich base-type derivatives.

C. R. Rodrigues, E. Gabano, M. Ravera, 2019, European journal of medicinal chemistry.

Assessment of the In Vivo Antiproliferative Activity of a Novel Platinum Particulate Pharmacophore

E. Monti, D. Osella, M. Gariboldi, 2009 .

Solvolysis of a Series of Cisplatin‐Like Complexes – Comparison between DNA‐Biosensor and Conductivity Data (Eur. J. Inorg. Chem. 34/2012)

J. Platts, D. Osella, E. Gabano, 2012 .

The influence of temperature on antiproliferative effects, cellular uptake and DNA platination of the clinically employed Pt(II)-drugs.

Domenico Osella, D. Osella, D. Colangelo, 2008, Journal of inorganic biochemistry.

Formulations of highly antiproliferative hydrophobic Pt(IV) complexes into lipidic nanoemulsions as delivery vehicles

D. Osella, L. Battaglia, E. Gabano, 2022, Inorganica Chimica Acta.