M. Klarić

发表

Dermal absorption study OECD TG 428 mass balance recommendations based on the EFSA database.

C. Wiemann, A. Schepky, S. Grégoire, 2019, Regulatory toxicology and pharmacology : RTP.

Solvent Solubility Testing of Cosmetics-Relevant Chemicals: Methodology and Correlation of Water Solubility to In Silico Predictions

N. Hewitt, H. Rothe, A. Schepky, 2017, Journal of Solution Chemistry.

Current status of human pluripotent stem cell based in vitro toxicity tests.

K. Meganathan, J. Hescheler, A. Sachinidis, 2013, Frontiers in bioscience.

Comparison of the metabolism of 10 chemicals in human and pig skin explants

D. Zalko, N. Hewitt, L. Debrauwer, 2018, Journal of applied toxicology : JAT.

Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol

E. Fabian, N. Hewitt, H. Rothe, 2019, Journal of applied toxicology : JAT.

The Threshold of Toxicological Concern (TTC) is a pragmatic tool for the safety assessment: Case studies of cosmetic ingredients with low consumer exposure.

M. Klarić, J. Rose, J. Head, 2021, Regulatory toxicology and pharmacology : RTP.

Expansion of the Cosmetics Europe skin sensitisation database with new substances and PPRA data.

S. Hoffmann, E. van Vliet, N. Alépée, 2022, Regulatory toxicology and pharmacology : RTP.

In vitro RHE skin sensitisation assays: Applicability to challenging substances.

D. Basketter, A. Irizar, B. Hubesch, 2019, Regulatory toxicology and pharmacology : RTP.

Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics‐relevant chemicals

N. Hewitt, H. Rothe, A. Schepky, 2020, Journal of applied toxicology : JAT.

Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.

M. Cronin, H. Clewell, E. Mombelli, 2022, Regulatory toxicology and pharmacology : RTP.

Cysteine cathepsins are not critical for TNF-alpha-induced cell death in T98G and U937 cells.

V. Turk, B. Turk, V. Stoka, 2009, Biochimica et biophysica acta.

Cosmetics Europe evaluation of 6 in silico skin penetration models

E. Fabian, N. Hewitt, J. Troutman, 2021, Computational Toxicology.

Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids.

A. Rolaki, N. Hewitt, J. Manwaring, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-To-Bedside

Ying S Hu, P. Sachdev, T. Das, 2012 .

A strategy for structuring and reporting a read-across prediction of toxicity.

T W Schultz, D J Knight, Terry W. Schultz, 2015, Regulatory toxicology and pharmacology : RTP.

Development of a next generation risk assessment framework for the evaluation of skin sensitisation of cosmetic ingredients.

Martina Klaric, Sebastian Hoffmann, Petra S Kern, 2020, Regulatory toxicology and pharmacology : RTP.

A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.

Bertrand Desprez, Martina Klaric, Gladys Ouédraogo, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

New Framework for a Non-Animal Approach Adequately Assures the Safety of Cosmetic Ingredients - A Case Study on Caffeine.

M. Cronin, H. Clewell, N. Hewitt, 2021, Regulatory toxicology and pharmacology : RTP.

Cosmetics Europe compilation of historical serious eye damage/eye irritation in vivo data analysed by drivers of classification to support the selection of chemicals for development and evaluation of alternative methods/strategies: the Draize eye test Reference Database (DRD)

João Barroso, Martina Klaric, Nathalie Alépée, 2016, Archives of Toxicology.

Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin™ using HPLC/UPLC-spectrophotometry in the MTT-reduction assay.

N. Alépée, U. Pfannenbecker, M. Klarić, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Non-animal methods to predict skin sensitization (II): an assessment of defined approaches**

Bertrand Desprez, Martina Klaric, David Allen, 2018, Critical reviews in toxicology.

Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database*

Bertrand Desprez, Martina Klaric, David Allen, 2018, Critical reviews in toxicology.

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment.

Martina Klaric, Andreas Schepky, Erwin van Vliet, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

EURL ECVAM WORKSHOP ON NEW GENERATION OF PHYSIOLOGICALLY-BASED KINETIC MODELS IN RISK ASSESSMENT

George Loizou, Judith C. Madden, Eann A. Patterson, 2017 .

N-terminally truncated forms of human cathepsin F accumulate in aggresome-like inclusions.

V. Turk, G. Guncar, I. Dolenc, 2013, Biochimica et biophysica acta.

Comparison of the metabolism of 10 cosmetics‐relevant chemicals in EpiSkin™ S9 subcellular fractions and in vitro human skin explants

N. Hewitt, H. Rothe, A. Schepky, 2019, Journal of applied toxicology : JAT.

Comparison of the Skin Penetration of 3 Metabolically Stable Chemicals Using Fresh and Frozen Human Skin

Martina Klaric, Richard Cubberley, Hélène Duplan, 2017, Skin Pharmacology and Physiology.

Comparison of protocols for measuring cosmetic ingredient distribution in human and pig skin.

H Rothe, J Eilstein, N. Hewitt, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Conceptual integration and humor: Can learners unpack the joke?

M. Klarić, 2020 .

Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop

Andrew Worth, Bertrand Desprez, Martina Klaric, 2019, Regulatory toxicology and pharmacology : RTP.

Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making

A Worth, N Suciu, J C Madden, 2019, Computational toxicology.

Comparison of protocols measuring diffusion and partition coefficients in the stratum corneum

N. Hewitt, J. Manwaring, H. Rothe, 2017, Journal of applied toxicology : JAT.

Use of a Simple in vitro Test to Assess Loss of Chemical due to Volatility during an in vitro Human Skin Absorption Study

N. Hewitt, H. Rothe, A. Schepky, 2019, Skin Pharmacology and Physiology.

State-of-the-art and new options to assess T cell activation by skin sensitizers: Cosmetics Europe Workshop.

L. Gribaldo, M. Pallardy, D. Naisbitt, 2018, ALTEX.

Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals.

A. De Smedt, B. De Wever, N. Alépée, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme.

Bertrand Desprez, Matt Dent, Detlef Keller, 2018, Toxicology in vitro : an international journal published in association with BIBRA.