A. Fabbri

发表

Cell-to-Cell Propagation of the Bacterial Toxin CNF1 via Extracellular Vesicles: Potential Impact on the Therapeutic Use of the Toxin

C. Fiorentini, M. Sargiacomo, S. Loizzo, 2015, Toxins.

Eye Drop Instillation of the Rac1 Modulator CNF1 Attenuates Retinal Gliosis and Ameliorates Visual Performance in a Rat Model of Hypertensive Retinopathy

C. Fiorentini, L. Ricceri, S. Travaglione, 2019, Neuroscience.

Enterotoxicity and Cytotoxicity of Vibrio parahaemolyticus Thermostable Direct Hemolysin in In Vitro Systems

C. Fiorentini, G. Donelli, A. Fasano, 2000, Infection and Immunity.

Cell Propagation of Cholera Toxin CTA ADP-Ribosylating Factor by Exosome Mediated Transfer

M. Falchi, K. Fecchi, M. Sargiacomo, 2018, International journal of molecular sciences.

Multinucleation and pro-inflammatory cytokine release promoted by fibrous fluoro-edenite in lung epithelial A549 cells.

C. Fiorentini, S. Travaglione, L. Paoletti, 2006, Toxicology in vitro : an international journal published in association with BIBRA.

Escherichia coli cytotoxic necrotizing factor 1: evidence for induction of actin assembly by constitutive activation of the p21 Rho GTPase

C. Fiorentini, P. Matarrese, G. Donelli, 1995, Infection and immunity.

Immunomodulatory properties of CNF1 toxin from E. coli: implications for colorectal carcinogenesis.

L. Bracci, A. Fabbri, 2022, American journal of cancer research.

Activation of Rho GTPases Triggers Structural Remodeling and Functional Plasticity in the Adult Rat Visual Cortex

L. Maffei, C. Fiorentini, M. Caleo, 2011, The Journal of Neuroscience.

New therapeutics from Nature: The odd case of the bacterial cytotoxic necrotizing factor 1.

C. Fiorentini, S. Travaglione, S. Loizzo, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Modulation of Rho GTPases rescues brain mitochondrial dysfunction, cognitive deficits and aberrant synaptic plasticity in female mice modeling Rett syndrome

C. Fiorentini, L. Ricceri, D. Valenti, 2015, European Neuropsychopharmacology.

Occurrence, Diversity, and Pathogenicity of HalophilicVibrio spp. and Non-O1 Vibrio cholerae from Estuarine Waters along the Italian Adriatic Coast

C. Fiorentini, P. Matarrese, G. Donelli, 1999, Applied and Environmental Microbiology.

Cytotoxic Necrotizing Factor 1 Prevents Apoptosis via the Akt/I (cid:1) B Kinase Pathway: Role of Nuclear Factor- (cid:1) B and Bcl-2 □ V

C. Fiorentini, P. Matarrese, S. Travaglione, 2007 .

Gut Microbiota and Colon Cancer: A Role for Bacterial Protein Toxins?

C. Fiorentini, S. Travaglione, A. Fabbri, 2020, International journal of molecular sciences.

The potential role of garlic (Allium sativum) against the multi-drug resistant tuberculosis pandemic: a review.

A. Fabbri, A. Geraci, Catia Dini, 2011, Annali dell'Istituto superiore di sanita.

A multinucleating Escherichia coli cytotoxin perturbs cell cycle in cultured epithelial cells.

C. Fiorentini, S. Travaglione, P. Filippini, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

Cytotoxic Necrotizing Factor 1 Enhances Reactive Oxygen Species-Dependent Transcription and Secretion of Proinflammatory Cytokines in Human Uroepithelial Cells

C. Fiorentini, G. Donelli, S. Travaglione, 2003, Infection and Immunity.

N‐Acetylcysteine protects epithelial cells against the oxidative imbalance due to Clostridium difficile toxins

C. Fiorentini, W. Malorni, A. Fabbri, 1999, FEBS letters.

Bacteroides fragilis enterotoxin induces cytoskeletal changes and surface blebbing in HT-29 cells

C. Fiorentini, G. Donelli, A. Fabbri, 1996, Infection and immunity.

The Bacterial Toxin CNF1 Induces Activation and Maturation of Human Monocyte-Derived Dendritic Cells

C. Fiorentini, M. Givskov, T. Krejsgaard, 2018, International journal of molecular sciences.

Hinderance of apoptosis and phagocytic behaviour induced by Escherichia coli cytotoxic necrotizing factor 1: two related activities in epithelial cells.

C. Fiorentini, P. Matarrese, P. Boquet, 1997, Biochemical and biophysical research communications.

Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2.

C. Fiorentini, P. Matarrese, S. Travaglione, 2007, Molecular biology of the cell.

The Bacterial Protein CNF1 as a Potential Therapeutic Strategy against Mitochondrial Diseases: A Pilot Study

C. Fiorentini, S. Servidei, S. Travaglione, 2018, International journal of molecular sciences.

Rho-activating Escherichia coli cytotoxic necrotizing factor 1: macropinocytosis of apoptotic bodies in human epithelial cells.

C. Fiorentini, A. Stringaro, W. Malorni, 2002, International journal of medical microbiology : IJMM.

The Escherichia coli protein toxin cytotoxic necrotizing factor 1 induces epithelial mesenchymal transition

C. Fiorentini, T. Krejsgaard, S. Travaglione, 2019, Cellular microbiology.

Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes.

C. Fiorentini, E. Lemichez, N. Gauthier, 2004, Molecular biology of the cell.

Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1.

C. Fiorentini, L. Ricceri, Domenico de Rasmo, 2015, Free radical biology & medicine.

Bacterial protein toxins: current and potential clinical use.

C. Fiorentini, S. Travaglione, A. Fabbri, 2008, Current medicinal chemistry.

Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1), a Toxin That Activates the Rho GTPase*

C. Fiorentini, P. Matarrese, G. Donelli, 1997, The Journal of Biological Chemistry.

Treatment with the Bacterial Toxin CNF1 Selectively Rescues Cognitive and Brain Mitochondrial Deficits in a Female Mouse Model of Rett Syndrome Carrying a MeCP2-Null Mutation

C. Fiorentini, L. Ricceri, D. Valenti, 2021, International journal of molecular sciences.

Clostridium difficile Toxin B Induces Apoptosis in Intestinal Cultured Cells

C. Fiorentini, P. Matarrese, A. Fattorossi, 1998, Infection and Immunity.

Hijacking Rho GTPases by protein toxins and apoptosis: molecular strategies of pathogenic bacteria

C. Fiorentini, S. Travaglione, A. Fabbri, 2003, Cell Death and Differentiation.

Human intestinal microbiota: cross-talk with the host and its potential role in colorectal cancer

P. Brigidi, M. Candela, C. Franceschi, 2011, Critical reviews in microbiology.

Dietary Polyphenols: Promising Adjuvants for Colorectal Cancer Therapies

L. Bracci, M. Del Cornò, A. Fabbri, 2021, Cancers.

Cytotoxic Necrotizing Factor 1 Prevents Apoptosis via the AKT/IKK pathway: Role of NF-κB and Bcl-2

C. Fiorentini, P. Matarrese, S. Travaglione, 2007 .

Escherichia coli Cytotoxic Necrotizing Factor 1 Blocks Cell Cycle G2/M Transition in Uroepithelial Cells

C. Fiorentini, S. Travaglione, P. Filippini, 2006, Infection and Immunity.

Cytotoxic necrotizing factor 1 hinders skeletal muscle differentiation in vitro by perturbing the activation/deactivation balance of Rho GTPases

C. Fiorentini, S. Rufini, S. Travaglione, 2005, Cell Death and Differentiation.

The Rac-Activating Toxin Cytotoxic Necrotizing Factor 1 Oversees NK Cell-Mediated Activity by Regulating the Actin/Microtubule Interplay

C. Fiorentini, W. Malorni, E. Straface, 2003, The Journal of Immunology.

Actin / Microtubule Interplay Cell-Mediated Activity by Regulating the Necrotizing Factor 1 Oversees NK The Rac-Activating Toxin Cytotoxic

C. Fiorentini, W. Malorni, E. Straface, 2003 .

Extracts from Cell Suspension Cultures of Strawberry (Fragaria x ananassa Duch): Cytotoxic Effects on Human Cancer Cells

C. Forni, S. Lucioli, F. Pastorino, 2019, Molecules.

Toxin-induced activation of Rho GTP-binding protein increases Bcl-2 expression and influences mitochondrial homeostasis.

C. Fiorentini, P. Matarrese, G. Donelli, 1998, Experimental cell research.

Clostridium difficile Toxin B Causes Apoptosis in Epithelial Cells by Thrilling Mitochondria

Blandine Geny, Michel R. Popoff, C. Fiorentini, 2007, Journal of Biological Chemistry.

The Rho-activating CNF1 toxin from pathogenic E. coli: A risk factor for human cancer development?

C. Fiorentini, S. Travaglione, A. Fabbri, 2008, Infectious Agents and Cancer.

Rac GTPase Instructs Nuclear Factor-κB Activation by Conveying the SCF Complex and IkBα to the Ruffling Membranes

C. Fiorentini, E. Lemichez, N. Gauthier, 2003 .

Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function.

L. McDonnell, C. Fiorentini, M. Caleo, 2016, Neuro-Oncology.

The bacterial protein toxin, cytotoxic necrotizing factor 1 (CNF1) provides long-term survival in a murine glioma model

C. Fiorentini, M. Caleo, Mario Costa, 2014, BMC Cancer.

The Cytotoxic Necrotizing Factor 1 from E. Coli: A Janus Toxin Playing with Cancer Regulators

C. Fiorentini, S. Travaglione, S. Loizzo, 2013, Toxins.

Modulation of RhoGTPases Improves the Behavioral Phenotype and Reverses Astrocytic Deficits in a Mouse Model of Rett Syndrome

C. Fiorentini, L. Ricceri, R. Canese, 2012, Neuropsychopharmacology.

Human melanoma cells express FGFR/Src/Rho signaling that entails an adhesion‐independent caveolin‐1 membrane association

A. Carè, F. Felicetti, C. Fiorentini, 2012, International journal of cancer.

Epithelial cells and expression of the phagocytic marker CD68: scavenging of apoptotic bodies following Rho activation.

C. Fiorentini, A. Stringaro, S. Fais, 2002, Toxicology in vitro : an international journal published in association with BIBRA.

Functional Analyses of the Crohn’s Disease Risk Gene LACC1

L. Vesterlund, Sabrina Ruhrmann, M. D’Amato, 2016, PloS one.

Mode of action of fibrous amphiboles: the case of Biancavilla (Sicily, Italy).

C. Fiorentini, S. Travaglione, S. Loizzo, 2014, Annali dell'Istituto superiore di sanita.

Enteric Toxins from Bacteria Colonizing Human Gut

C. Fiorentini, G. Donelli, P. Mastrantonio, 2000 .

Bacterial protein toxins in human cancers.

C. Fiorentini, A. Fabbri, Francesca Rosadi, 2016, Pathogens and disease.

Association of Polygenic Risk Score and Bacterial Toxins at Screening Colonoscopy with Colorectal Cancer Progression: A Multicenter Case-Control Study

C. Fiorentini, M. D’Amato, L. Nisticò, 2021, Toxins.

Helicobacter pylori Counteracts the Apoptotic Action of Its VacA Toxin by Injecting the CagA Protein into Gastric Epithelial Cells

A. Sciullo, A. Oldani, M. Cormont, 2009, PLoS pathogens.

Vibrio parahaemolyticus Thermostable Direct Hemolysin Modulates Cytoskeletal Organization and Calcium Homeostasis in Intestinal Cultured Cells

C. Fiorentini, P. Matarrese, G. Donelli, 1999, Infection and Immunity.

Effects of the Escherichia coli Bacterial Toxin Cytotoxic Necrotizing Factor 1 on Different Human and Animal Cells: A Systematic Review

C. Fiorentini, S. Travaglione, A. Fabbri, 2021, International journal of molecular sciences.

Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1): Toxin Biology, in Vivo Applications and Therapeutic Potential

C. Fiorentini, S. Travaglione, A. Fabbri, 2010, Toxins.

The E. coli CNF1 as a Pioneering Therapy for the Central Nervous System Diseases

C. Fiorentini, S. Travaglione, S. Loizzo, 2014, Toxins.

CNF1 Increases Brain Energy Level, Counteracts Neuroinflammatory Markers and Rescues Cognitive Deficits in a Murine Model of Alzheimer's Disease

C. Fiorentini, R. Rimondini, S. Travaglione, 2013, PloS one.

Enhancement of mitochondrial ATP production by the Escherichia coli cytotoxic necrotizing factor 1

R. Carrozzo, C. Fiorentini, A. Torraco, 2014, The FEBS journal.

Integrated Cancer Treatment in the Course of Metastatic Pancreatic Cancer: Complete Resolution in 2 Cases

C. Fiorentini, M. Bonucci, A. Fabbri, 2018, Integrative cancer therapies.

Effects of the Rho GTPase‐activating toxin CNF1 on fibroblasts derived from Rett syndrome patients: A pilot study

C. Fiorentini, L. Ricceri, C. Fallerini, 2023, Journal of cellular and molecular medicine.

Cnf1 Variants Endowed with the Ability to Cross the Blood–Brain Barrier: A New Potential Therapeutic Strategy for Glioblastoma

C. Fiorentini, L. Ricceri, M. Tutino, 2020, Toxins.

Pharmacological Stimulation of the Brain Serotonin Receptor 7 as a Novel Therapeutic Approach for Rett Syndrome

E. Lacivita, M. Leopoldo, L. Ricceri, 2014, Neuropsychopharmacology.

CNF1 Improves Astrocytic Ability to Support Neuronal Growth and Differentiation In vitro

C. Fiorentini, S. Travaglione, A. Fabbri, 2012, PloS one.

Activation of rho GTPases by cytotoxic necrotizing factor 1 induces macropinocytosis and scavenging activity in epithelial cells.

C. Fiorentini, A. Stringaro, W. Malorni, 2001, Molecular biology of the cell.

Enhancement of learning and memory after activation of cerebral Rho GTPases

C. Fiorentini, S. Travaglione, C. Zona, 2007, Proceedings of the National Academy of Sciences.

The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating μ-opioid receptors

C. Fiorentini, W. Malorni, E. Straface, 2009, PAIN®.

High yield purification and first structural characterization of the full‐length bacterial toxin CNF1

A. Vergara, C. Fiorentini, M. Tutino, 2018, Biotechnology progress.

Comparison of microbiological profile of enterotoxigenic Bacteroides fragilis (ETBF) isolates from subjects with colorectal cancer (CRC) or intestinal pre-cancerous lesions versus healthy individuals and evaluation of environmental factors involved in intestinal dysbiosis.

L. Sanchez-Mete, V. Stigliano, R. De Angelis, 2023, Anaerobe.

Epithelial cells challenged with a Rac-activating E. coli cytotoxin acquire features of professional phagocytes.

C. Fiorentini, A. Fabbri, R. Rivabene, 2002, Toxicology in vitro : an international journal published in association with BIBRA.

Correction: CNF1 Increases Brain Energy Level, Counteracts Neuroinflammatory Markers and Rescues Cognitive Deficits in a Murine Model of Alzheimer's Disease

C. Fiorentini, R. Rimondini, S. Travaglione, 2013, PLoS ONE.