Hiroya Kobayashi

发表

Focal adhesion kinase as an immunotherapeutic target

H. Iizuka, M. Honma, E. Celis, 2009, Cancer Immunology, Immunotherapy.

Severe spruelike enteropathy and collagenous colitis caused by olmesartan

K. Kishi, N. Ehira, M. Uebayashi, 2021, BMC Gastroenterology.

Promiscuous Peptides on the Nontypeable Haemophilus Influenzae P6 Outer Membrane Protein

Y. Harabuchi, Hiroya Kobayashi, Yoshiya Ishida, 2008, Journal of Clinical Immunology.

Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site

K. Ishibashi, E. Celis, T. Kumai, 2017, Cancer Immunology, Immunotherapy.

Contribution of long-chain fatty acid to induction of myeloid-derived suppressor cell (MDSC)-like cells – induction of MDSC by lipid vesicles (liposome)

M. Fujihara, H. Azuma, Tsunehisa Nagamori, 2020, Immunopharmacology and immunotoxicology.

c-Met is a novel tumor associated antigen for T-cell based immunotherapy against NK/T cell lymphoma

K. Ishibashi, E. Celis, T. Kumai, 2015, Oncoimmunology.

A clinicocytopathological study of invasive micropapillary carcinoma of the breast

Hiroya Kobayashi, M. Tateno, M. Yokoyama, 2011 .

A clinicocytopathological study of typical medullary carcinoma of the breast

Hiroya Kobayashi, M. Tateno, M. Yokoyama, 2011 .

PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma

K. Ishibashi, E. Celis, H. Takei, 2019, Journal of Translational Medicine.

The feasibility of circulating tumor DNA analysis as a marker of recurrence in triple-negative breast cancer.

S. Okazaki, K. Ishibashi, H. Takei, 2021, Oncology letters.

CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes

K. Ishibashi, Yukio Fujiwara, T. Kumai, 2021, The Journal of experimental medicine.

Novel targets for natural killer/T-cell lymphoma immunotherapy.

T. Kumai, Y. Harabuchi, Hiroya Kobayashi, 2016, Immunotherapy.

Liposomal microparticle injection can induce myeloid-derived suppressor cells (MDSC)-like cells in vivo

M. Fujihara, H. Azuma, Hiroya Kobayashi, 2017, Immunopharmacology and immunotoxicology.

Helper T-cell based immunotherapy combined with adjuvants in head and neck squamous cell carcinoma

M. Takahara, T. Kumai, Y. Harabuchi, 2014 .

Assessment of the change in cetuximab‐induced antibody‐dependent cellular cytotoxicity activity of natural killer cells by steroid

T. Kumai, Y. Harabuchi, Hiroya Kobayashi, 2016, Head & neck.

Analysis of anchor residues in a naturally processed HLA-DR53 ligand

Hiroya Kobayashi, Keisuke Sato, S. Kimura, 2007, Immunogenetics.

Identification of an antigenic epitope for helper T lymphocytes from carcinoembryonic antigen.

J. Prieto, B. Sangro, E. Huarte, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Analysis of Naturally Processed Human Histocompatibility Leukocyte Antigen Class I‐Bound Peptides from Hepatocellular Carcinoma Tissues in vivo

M. Nakashima, Hiroya Kobayashi, Keisuke Sato, 1995, Japanese journal of cancer research : Gann.

Identification and Characterization of a T-Helper Peptide from Carcinoembryonic Antigen

J. Prieto, J. Lasarte, E. Celis, 2004, Clinical Cancer Research.

Epitope Specific for an MHC Class II Promiscuous T Cells + Lymphoproliferation by CD 4 Inhibition of EBV-Induced

C. Payá, E. Celis, R. Omiya, 2002 .

Interleukin 15 promotes antigen-independent in vitro expansion and long-term survival of antitumor cytotoxic T lymphocytes.

R. Kennedy, E. Celis, R. Giuntoli, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Lymphocytes from Carcinoembryonic Antigen Identification of an Antigenic Epitope for Helper T Updated Version

J. Prieto, B. Sangro, E. Huarte, 2002 .

Direct costimulation of tumor-reactive CTL by helper T cells potentiate their proliferation, survival, and effector function.

R. Kennedy, E. Celis, R. Giuntoli, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Histocompatibility Complex Class II Alleles Promiscuous MAGE-A 3 Epitope Presented by Various Major Tumor-reactive T Helper Lymphocytes Recognize a Updated

E. Appella, D. Hoon, E. Celis, 2001 .

Epigenetic modification augments the immunogenicity of human leukocyte antigen G serving as a tumor antigen for T cell-based immunotherapy

K. Ishibashi, E. Celis, T. Kumai, 2016, Oncoimmunology.

Induction of tumor-reactive T helper responses by a posttranslational modified epitope from tumor protein p53

K. Ishibashi, E. Celis, T. Kumai, 2014, Cancer Immunology, Immunotherapy.

Fungal metabolite (+)-terrein suppresses IL-6/sIL-6R-induced CSF1 secretion by inhibiting JAK1 phosphorylation in human gingival fibroblasts

Soichiro Ibaragi, S. Takashiba, M. Nakayama, 2018, Heliyon.

Sustained Persistence of IL2 Signaling Enhances the Antitumor Effect of Peptide Vaccines through T-cell Expansion and Preventing PD-1 Inhibition

H. Sultan, E. Celis, Juan Wu, 2018, Cancer Immunology Research.

Recognition of Adult T-Cell Leukemia/Lymphoma Cells by CD4+ Helper T Lymphocytes Specific for Human T-Cell Leukemia Virus Type I Envelope Protein

M. Yanai, E. Celis, R. Omiya, 2004, Clinical Cancer Research.

CD4+ T-cells from peripheral blood of a patient with psoriasis recognize keratin 14 peptide but not 'homologous' streptococcal M-protein epitope.

A. Ishida-Yamamoto, Hidetoshi Takahashi, H. Iizuka, 2002, Journal of dermatological science.

Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb.

A. Ishida-Yamamoto, K. Ishibashi, Y. Harabuchi, 2017, Biochemical and biophysical research communications.

A tumor metastasis‐associated molecule TWIST1 is a favorable target for cancer immunotherapy due to its immunogenicity

K. Ishibashi, T. Kumai, T. Nagato, 2022, Cancer science.

Oral infection control to assist infliximab therapy in a Behçet's disease patient with severe eye inflammation in response to dental treatment: a case report

T. Matsuo, S. Takashiba, H. Makino, 2014, Clinical case reports.

The role of CCL22/macrophage-derived chemokine in allergic rhinitis.

M. Yanai, Y. Harabuchi, Hiroya Kobayashi, 2007, Clinical immunology.

Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer

E. Celis, T. Kumai, Hiroya Kobayashi, 2011, Journal of Translational Medicine.

Induction of EBV-latent membrane protein 1-specific MHC class II-restricted T-cell responses against natural killer lymphoma cells.

M. Takahara, E. Celis, Y. Harabuchi, 2008, Cancer research.

In vitro Peptide Immunization of Target Tax Protein Human T-Cell Leukemia Virus Type 1–Specific CD4+ Helper T Lymphocytes

Yuetsu Tanaka, E. Celis, Hiroya Kobayashi, 2006, Clinical Cancer Research.

Defining MHC class II T helper epitopes for WT1 tumor antigen

E. Celis, T. Nagato, Hiroya Kobayashi, 2006, Cancer Immunology, Immunotherapy.

Optimization of Peptide Vaccines to Induce Robust Antitumor CD4 T-cell Responses

H. Sultan, E. Celis, Hyun-Il Cho, 2016, Cancer Immunology Research.

Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy

M. Takahara, K. Kishibe, K. Ishibashi, 2017, Cancer Immunology, Immunotherapy.

Expression of Interleukin-9 in Nasal Natural Killer/T-Cell Lymphoma Cell Lines and Patients

M. Takahara, K. Kishibe, Y. Harabuchi, 2005, Clinical Cancer Research.

Cyclin-dependent kinase 1 and survivin as potential therapeutic targets against nasal natural killer/T-cell lymphoma

M. Takahara, K. Kishibe, D. Nadal, 2019, Laboratory Investigation.

Interferon-γ-Dependent Stimulation of Fas Antigen in SV40-Transformed Human Keratinocytes: Modulation of the Apoptotic Process by Protein Kinase C

Hidetoshi Takahashi, H. Iizuka, S. Matsuo, 1995 .

A case of primary histiocytic sarcoma arising from a neck lymph node.

T. Wada, Y. Harabuchi, Hiroya Kobayashi, 2022, Ear, nose, & throat journal.

Modulation of hepatic granulomatous responses by transgene expression of DAP12 or TREM-1-Ig molecules.

T. Matsuno, M. Yanai, Z. Xing, 2003, The American journal of pathology.

Effects of STING stimulation on macrophages: STING agonists polarize into “classically” or “alternatively” activated macrophages?

T. Nagato, Hiroya Kobayashi, T. Ohkuri, 2017, Human vaccines & immunotherapeutics.

A critical role of STING-triggered tumor-migrating neutrophils for anti-tumor effect of intratumoral cGAMP treatment

T. Kumai, Y. Harabuchi, T. Nagato, 2021, Cancer Immunology, Immunotherapy.

Visinin-Like Protein-3 Modulates the Interaction Between Cytochrome b5 and NADH-Cytochrome b5 Reductase in a Ca2+-Dependent Manner

B. Albensi, G. Odero, Solmaz Nafez, 2016, Cell Biochemistry and Biophysics.

Expression and functional role of MDL‐1 (CLEC5A) in mouse myeloid lineage cells

T. Nagato, Hiroya Kobayashi, Makoto Azumi, 2009, Journal of Leukocyte Biology.

IFN‐α/β‐mediated NK2R expression is related to the malignancy of colon cancer cells

K. Ikeo, A. Taketomi, T. Nagato, 2022, Cancer science.

Neuropeptide signaling through neurokinin-1 and neurokinin-2 receptors augments antigen presentation by human dendritic cells.

S. Iwabuchi, Y. Tanino, S. Terada, 2015, The Journal of allergy and clinical immunology.

Identification of human T-cell epitopes and highly immunogenic analog peptides on the non-typeable Haemophilus influenzae P6 outer membrane protein.

M. Yanai, Y. Harabuchi, Hiroya Kobayashi, 2006, Clinical immunology.

Decreased expression of retinoid X receptor isoforms in human thyroid carcinomas.

A. Sugawara, Hiroya Kobayashi, Keisuke Sato, 2004, The Journal of clinical endocrinology and metabolism.

An infantile case of hereditary folate malabsorption with sudden development of pulmonary hemorrhage: a case report

Hiroya Kobayashi, H. Azuma, Marino Nagata, 2022, Journal of Medical Case Reports.

CCL17 and CCL22/CCR4 signaling is a strong candidate for novel targeted therapy against nasal natural killer/T-cell lymphoma

M. Takahara, K. Kishibe, E. Celis, 2015, Cancer Immunology, Immunotherapy.

Neuronal Calcium Sensor Protein Visinin-like Protein-3 Interacts with Microsomal Cytochrome b5 in a Ca2+-dependent Manner*

M. Yanai, T. Sasajima, T. Nagato, 2004, Journal of Biological Chemistry.

The Fungal Metabolite (+)-Terrein Abrogates Ovariectomy-Induced Bone Loss and Receptor Activator of Nuclear Factor-κB Ligand–Induced Osteoclastogenesis by Suppressing Protein Kinase-C α/βII Phosphorylation

S. Takashiba, M. Nakayama, S. Suga, 2021, Frontiers in Pharmacology.

Characterization of human CD4 helper T cell responses against Aurora kinase A

H. Kakizaki, E. Celis, Y. Harabuchi, 2010, Cancer Immunology, Immunotherapy.

Naturally processed HLA-DR9/DR53 (DRB1*0901/DRB4*0101)-bound peptides

M. Taneichi, Hiroya Kobayashi, Keisuke Sato, 2004, Immunogenetics.

A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy

T. Okumura, K. Ishibashi, Takaaki Sasaki, 2021, Cancer science.

Peptide vaccines in cancer-old concept revisited.

E. Celis, T. Kumai, Y. Harabuchi, 2017, Current opinion in immunology.

Functional Analysis of Birch Pollen Allergen Bet v 1-Specific Regulatory T Cells1

M. Yanai, E. Celis, Y. Harabuchi, 2007, The Journal of Immunology.

Tumor-derived TGF-β and prostaglandin E2 attenuate anti-tumor immune responses in head and neck squamous cell carcinoma treated with EGFR inhibitor

E. Celis, T. Kumai, Y. Harabuchi, 2014, Journal of Translational Medicine.

Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma

E. Celis, T. Kumai, Y. Harabuchi, 2015, Scientific Reports.

Recognition of prostate and melanoma tumor cells by six-transmembrane epithelial antigen of prostate-specific helper T lymphocytes in a human leukocyte antigen class II-restricted manner.

H. Kakizaki, H. Iizuka, E. Celis, 2007, Cancer research.

Phosphorylated vimentin as an immunotherapeutic target against metastatic colorectal cancer

Y. Sumi, T. Kumai, Y. Harabuchi, 2020, Cancer Immunology, Immunotherapy.

DAP12 ITAM motif regulates differentiation and apoptosis in M1 leukemia cells.

Hiroya Kobayashi, Keisuke Sato, N. Aoki, 2002, Biochemical and biophysical research communications.

Bet v 1-Specific Regulatory T Cells Functional Analysis of Birch Pollen Allergen

M. Yanai, E. Celis, Y. Harabuchi, 2006 .

Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma

M. Takahara, K. Kishibe, E. Celis, 2020, Oncoimmunology.

Six-transmembrane epithelial antigen of the prostate as an immunotherapeutic target for renal cell and bladder cancer.

H. Kakizaki, Hiroya Kobayashi, Makoto Azumi, 2010, The Journal of urology.

Recognition of Prostate and Breast Tumor Cells by Helper T Lymphocytes Specific for a Prostate and Breast Tumor-Associated Antigen, TARP

E. Celis, R. Omiya, T. Nagato, 2005, Clinical Cancer Research.

Inhibition of EBV-Induced Lymphoproliferation by CD4+ T Cells Specific for an MHC Class II Promiscuous Epitope1

Hiroya Kobayashi, C. Payá, E. Celis, 2002, The Journal of Immunology.

Existence of MHC class I-restricted alloreactive CD4+ T cells reacting with peptide transporter-deficient cells

E. Celis, Hiroya Kobayashi, Keisuke Sato, 2001, Immunogenetics.

Peptide epitope identification for tumor-reactive CD4 T cells.

E. Celis, Hiroya Kobayashi, 2008, Current opinion in immunology.

A naturally processed HLA-DR-bound peptide from the IL-9 receptor alpha of HTLV-1-transformed T cells serves as a T helper epitope

E. Celis, T. Kumai, Hiroya Kobayashi, 2012, Cancer Immunology, Immunotherapy.

Identification of naturally processed helper T-cell epitopes from prostate-specific membrane antigen using peptide-based in vitro stimulation.

S. Senju, Y. Nishimura, M. Yanai, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma

K. Ishibashi, E. Celis, T. Kumai, 2018, Oncoimmunology.

Expression of soluble CD27 in extranodal natural killer/T-cell lymphoma, nasal type: potential as a biomarker for diagnosis and CD27/CD70-targeted therapy

M. Takahara, K. Kishibe, Michihisa Kono, 2023, Cancer Immunology, Immunotherapy.

Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma

M. Takahara, K. Kishibe, Michihisa Kono, 2022, Oncoimmunology.

Neuroprotective effect of water-dispersible hesperetin in retinal ischemia reperfusion injury

A. Yoshida, T. Nagaoka, H. Yokota, 2015, Japanese Journal of Ophthalmology.

Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery

M. Takahara, K. Kishibe, E. Celis, 2021, Cancer Immunology, Immunotherapy.

Intratumoral STING activations overcome negative impact of cisplatin on antitumor immunity by inflaming tumor microenvironment in squamous cell carcinoma.

T. Kumai, Y. Harabuchi, T. Nagato, 2019, Biochemical and biophysical research communications.

Tumor-derived TGF-β and prostaglandin E2 attenuate anti-tumor immune responses in head and neck squamous cell carcinoma treated with EGFR inhibitor

E. Celis, T. Kumai, Y. Harabuchi, 2014, Journal of Translational Medicine.

Celecoxib promotes the efficacy of STING‐targeted therapy by increasing antitumor CD8+ T‐cell functions via modulating glucose metabolism of CD11b+Ly6G+ cells

T. Nagato, Hiroya Kobayashi, K. Oikawa, 2022, International journal of cancer.

The fungal metabolite (+)-terrein abrogates osteoclast differentiation via suppression of the RANKL signaling pathway through NFATc1.

S. Takashiba, M. Nakayama, S. Suga, 2020, International immunopharmacology.

PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma

K. Ishibashi, E. Celis, H. Takei, 2019, Journal of translational medicine.

Mitogen‐activated protein kinase inhibition augments the T cell response against HOXB7‐expressing tumor through human leukocyte antigen upregulation

M. Takahara, Michihisa Kono, T. Kumai, 2022, Cancer Science.

A clinicocytological study of tubular carcinoma of the breast

Hiroya Kobayashi, M. Tateno, S. Hayashi, 2010 .

Brachyury-targeted immunotherapy combined with gemcitabine against head and neck cancer

M. Takahara, K. Kishibe, Michihisa Kono, 2023, Cancer Immunology, Immunotherapy.

Tyrosinase epitope recognized by an HLA-DR-restricted T-cell line from a Vogt-Koyanagi-Harada disease patient

Hiroya Kobayashi, Keisuke Sato, S. Kimura, 1998, Immunogenetics.

Identification of helper T-cell epitopes that encompass or lie proximal to cytotoxic T-cell epitopes in the gp100 melanoma tumor antigen.

E. Celis, Jun Lu, H Kobayashi, 2001, Cancer research.

Optimization of Peptide Vaccines to Induce Robust Antitumor CD4 T-cell Responses

H. Sultan, E. Celis, Hyun-Il Cho, 2016, Cancer Immunology Research.

Mitogen‐activated protein kinase inhibition augments the T cell response against HOXB7‐expressing tumor through human leukocyte antigen upregulation

M. Takahara, Michihisa Kono, T. Kumai, 2022, Cancer Science.

Defining promiscuous MHC class II helper T-cell epitopes for the HER2/neu tumor antigen.

E. Appella, E. Celis, E Appella, 2000, Cancer research.

Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb.

K. Ishibashi, Y. Harabuchi, T. Nagato, 2017, Biochemical and biophysical research communications.

Hypoxia-Targeted Immunotherapy with PD-1 Blockade in Head and Neck Cancer

K. Kishibe, T. Kumai, T. Nagato, 2024, Cancers.

Immunotherapy targeting tumor‐associated antigen in a mouse model of head and neck cancer

K. Kishibe, Michihisa Kono, T. Kumai, 2024, Head & neck.