Jaekwon Lee

发表

The H2O2 Stimulon in Saccharomyces cerevisiae *

J. Buhler, M. Perrot, H. Boucherie, 1998, The Journal of Biological Chemistry.

X‐linked spinal muscular atrophy in mice caused by autonomous loss of ATP7A in the motor neuron

J. Gitlin, G. Weisman, Jaekwon Lee, 2015, The Journal of pathology.

Autonomous requirements of the Menkes disease protein in the nervous system.

J. Gitlin, Shan Zhu, G. Weisman, 2015, American journal of physiology. Cell physiology.

Altered microglial copper homeostasis in a mouse model of Alzheimer’s disease

A. Bush, Grace Y Sun, G. Weisman, 2010, Journal of neurochemistry.

Biochemical Characterization of the Human Copper Transporter Ctr1*

D. Thiele, M. M. Peña, Jaekwon Lee, 2002, The Journal of Biological Chemistry.

Copper transport into the secretory pathway is regulated by oxygen in macrophages

A. Bush, Y. Fulcher, T. Quinn, 2009, Journal of Cell Science.

Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis

Christopher J. Chang, F. Gonzalez, Jung-Hwan Kim, 2021, Nature communications.

Copper-stimulated Endocytosis and Degradation of the Human Copper Transporter, hCtr1*

D. Thiele, Jaekwon Lee, M. Petris, 2003, The Journal of Biological Chemistry.

Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane*

Jaekwon Lee, Heejeong Kim, Nathan Smith, 2016, The Journal of Biological Chemistry.

Proteasome Recruitment to the Endoplasmic Reticulum 1 Endoplasmic Reticulum-associated Degradation of Pca 1 p , a Polytopic Protein , via Interaction with the Proteasome at the Membrane

Jaekwon Lee, M. Zhao, Heejeong Kim, 2016 .

Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress

B. Jeon, Soonkyu Chung, M. Kundu, 2020, International journal of molecular sciences.

Metal accumulation and transport in the ovary of the lizard Podarcis sicula

D. Thiele, Jaekwon Lee, E. Parisi, 2004 .

Copper–zinc superoxide dismutase-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis induced with myelin oligodendrocyte glycoprotein 35–55

C. Massilamany, A. Gangaplara, J. Reddy, 2013, Journal of Neuroimmunology.

Dietary Iron Deficiency Modulates Adipocyte Iron Homeostasis, Adaptive Thermogenesis, and Obesity in C57BL/6 Mice.

Soonkyu Chung, Zhenhua Liu, Jaekwon Lee, 2021, The Journal of nutrition.

Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development

D. Thiele, J. Prohaska, Jaekwon Lee, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Organ-specific regulation of ATP7A abundance is coordinated with systemic copper homeostasis

Byung-Eun Kim, Jaekwon Lee, Heejeong Kim, 2017, Scientific Reports.

SLC31 (CTR) family of copper transporters in health and disease.

Jaekwon Lee, Heejeong Kim, Xiaobin Wu, 2013, Molecular aspects of medicine.

Urinary Copper Elevation in a Mouse Model of Wilson's Disease Is a Regulated Process to Specifically Decrease the Hepatic Copper Load

O. Muzik, J. Kaplan, Jaekwon Lee, 2012, PloS one.

Iron Insufficiency Compromises Motor Neurons and Their Mitochondrial Function in Irp2-Null Mice

James B. Mitchell, R. Sougrat, C. Beaumont, 2011, PloS one.

A Role for The ATP7A Copper Transporter in Tumorigenesis and Cisplatin Resistance

Shan Zhu, Jaekwon Lee, M. Petris, 2017, Journal of Cancer.

Characterization of Mouse Embryonic Cells Deficient in the Ctr1 High Affinity Copper Transporter

D. Thiele, Jaekwon Lee, M. Petris, 2002, The Journal of Biological Chemistry.

Deletion of hepatic Ctr1 reveals its function in copper acquisition and compensatory mechanisms for copper homeostasis.

H. Son, Jaekwon Lee, Heejeong Kim, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase

T. Rouault, C. Philpott, Pamela M. Smith, 2014, Proceedings of the National Academy of Sciences.

Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2

D. Thiele, Jaekwon Lee, Brandon L. Logeman, 2017, The Journal of Biological Chemistry.

Regulation and Function of the Copper Ion Transport Machinery

D. Thiele, Jaekwon Lee, 2002 .

Cadmium Transport in Eukaryotes

Jaekwon Lee, Nathan Smith, Wenzhong Wei, 2013 .

NCOA4 Regulates Iron Recycling and Responds to Hepcidin Activity and Lipopolysaccharide in Macrophages

Jaekwon Lee, Xiaoli Chen, M. Ryu, 2022, Antioxidants.

Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

I. Herskowitz, D. Thiele, Jaekwon Lee, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Oocyte CTR1 is not essential for cisplatin-induced oocyte death of primordial follicle

Yi Luan, Jaekwon Lee, Amirhossein Abazarikia, 2022, microPublication biology.

A Role for the ATP7A Copper-transporting ATPase in Macrophage Bactericidal Activity*

K. Fritsche, Jaekwon Lee, T. Kambe, 2009, The Journal of Biological Chemistry.

Distinct Mechanisms for Ctr1-mediated Copper and Cisplatin Transport*

Devis Sinani, Jaekwon Lee, Heejeong Kim, 2007, Journal of Biological Chemistry.

Biochemical and Genetic Analyses of Yeast and Human High Affinity Copper Transporters Suggest a Conserved Mechanism for Copper Uptake*

D. Thiele, S. Puig, Jaekwon Lee, 2002, The Journal of Biological Chemistry.

Identification of Methionine-rich Clusters That Regulate Copper-stimulated Endocytosis of the Human Ctr1 Copper Transporter*

D. Thiele, Jaekwon Lee, M. Petris, 2004, Journal of Biological Chemistry.

Cadmium-mediated rescue from ER-associated degradation induces expression of its exporter

Jaekwon Lee, Nathan Smith, D. Adle, 2009, Proceedings of the National Academy of Sciences.

Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways

J. Rochet, L. Stanciu, E. M. Reyes-Reyes, 2015, Neurobiology of Disease.

Mobilization of Intracellular Copper Stores by the Ctr2 Vacuolar Copper Transporter*

D. Thiele, E. Rees, Jaekwon Lee, 2004, Journal of Biological Chemistry.

Yap1 and Skn7 Control Two Specialized Oxidative Stress Response Regulons in Yeast*

J. Garin, C. Godon, Gilles Lagniel, 1999, The Journal of Biological Chemistry.

A New Antioxidant with Alkyl Hydroperoxide Defense Properties in Yeast*

C. Godon, Jaekwon Lee, J. Labarre, 1999, The Journal of Biological Chemistry.

Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.

R. Tuder, Anamika Singh, G. Kovtunovych, 2013, Cell metabolism.

High affinity copper transport protein in the lizard Podarcis sicula: molecular cloning, functional characterization and expression in somatic tissues, follicular oocytes and eggs.

D. Thiele, Jaekwon Lee, E. Parisi, 2002, Biochimica et biophysica acta.

Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation

P. Arosio, S. David, R. P. Santos, 2015, Neurobiology of Disease.

Essential role of systemic iron mobilization and redistribution for adaptive thermogenesis through HIF2-α/hepcidin axis

T. Helikar, S. Vaulont, Soonkyu Chung, 2021, Proceedings of the National Academy of Sciences.

Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunits.

M. Simpson, E. Biterova, Jaekwon Lee, 2011, Biochemistry.

Cadmium and Secondary Structure-dependent Function of a Degron in the Pca1p Cadmium Exporter*

J. Seravalli, Jaekwon Lee, Heejeong Kim, 2016, The Journal of Biological Chemistry.

Oma1 Links Mitochondrial Protein Quality Control and TOR Signaling To Modulate Physiological Plasticity and Cellular Stress Responses

I. Bohovych, O. Khalimonchuk, A. Barrientos, 2016, Molecular and Cellular Biology.

Cellular Zinc Deficiency Impairs Heme Biosynthesis in Developing Erythroid Progenitors

Jaekwon Lee, M. Ryu, Juyoung Kim, 2023, Nutrients.

Roles for intracellular cation transporters in respiratory growth of yeast.

Xue-qing Chen, Jiang Bian, Jaekwon Lee, 2019, Metallomics : integrated biometal science.

Potassium and the K + / H + Exchanger Kha 1 p Promote Binding of Copper to ApoFet 3 p Multi-copper

D. Kosman, P. Hart, E. Cera, 2017 .

Potassium and the K+/H+ Exchanger Kha1p Promote Binding of Copper to ApoFet3p Multi-copper Ferroxidase*

D. Kosman, E. Di Cera, P. Hart, 2016, The Journal of Biological Chemistry.

YCF1-mediated cadmium resistance in yeast is dependent on copper metabolism and antioxidant enzymes.

O. Khalimonchuk, J. Seravalli, Jaekwon Lee, 2014, Antioxidants & redox signaling.

Expressional Control of a Cadmium-transporting P1B-type ATPase by a Metal Sensing Degradation Signal*

Jaekwon Lee, D. Adle, 2008, Journal of Biological Chemistry.

A Cadmium-transporting P1B-type ATPase in Yeast Saccharomyces cerevisiae*

Devis Sinani, Jaekwon Lee, Heejeong Kim, 2007, Journal of Biological Chemistry.

Molecular mechanisms of copper homeostasis in yeast

Jaekwon Lee, Heejeong Kim, D. Adle, 2005 .

The thermogenic characteristics of adipocytes are dependent on the regulation of iron homeostasis

Soonkyu Chung, Zhenhua Liu, Yongeun Kim, 2021, The Journal of biological chemistry.

A novel functional role of nickel in sperm motility and eukaryotic cell growth.

Xiǎohóng Shí, M. Tao, Jiang Bian, 2019, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

The Intestinal Copper Exporter CUA-1 Is Required for Systemic Copper Homeostasis in Caenorhabditis elegans*♦

A. Sharma, Byung-Eun Kim, Shang Jia, 2016, The Journal of Biological Chemistry.

Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis

Han Yang, C. Fenollar-Ferrer, K. Krausz, 2021, Nature Communications.

Copper Transport Activity of Yeast Ctr1 Is Down-regulated via Its C Terminus in Response to Excess Copper*

Devis Sinani, Jaekwon Lee, Heejeong Kim, 2009, Journal of Biological Chemistry.

CHCA-1 is a copper-regulated CTR1 homolog required for normal development, copper accumulation, and copper-sensing behavior in Caenorhabditis elegans

A. Sharma, Byung-Eun Kim, Jaekwon Lee, 2018, The Journal of Biological Chemistry.

A delicate balance: homeostatic control of copper uptake and distribution.

D. Thiele, J. Lee, D J Thiele, 1999, The Journal of nutrition.

Cadmium and Secondary Structure-dependent Function of a Degron in the Pca1p Cadmium Exporter*

J. Seravalli, Jaekwon Lee, Heejeong Kim, 2016, Journal of Biological Chemistry.

Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways

J. Rochet, L. Stanciu, R. Franco, 2015, Neurobiology of Disease.

Iron Insufficiency Compromises Motor Neurons and Their Mitochondrial Function in Irp2-Null Mice

James B. Mitchell, R. Sougrat, C. Beaumont, 2011, PloS one.

Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant.

D. Thiele, J. Lee, T. Glover, 2000, Gene.