D. Otero

发表

Retro-inverso prosaptide peptides retain bioactivity, are stable In vivo, and are blood-brain barrier permeable.

W. Banks, J. O'brien, E. M. Taylor, 2000, The Journal of pharmacology and experimental therapeutics.

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

E. Masliah, Y. Ihara, M. Yoshimoto, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Axonal responses to cellularly delivered NT-4/5 after spinal cord injury

A. Blesch, N. Weidner, Hong Yang, 2004, Molecular and Cellular Neuroscience.

Amino Acid Sequence Rerms Represents the Active Domain of Amyloid /a4 Protein Precursor That Promotes Fibroblast Growth

H. Ninomiya, D. Otero, T. Saitoh, 1993 .

Proteins that bind to the RERMS region of β amyloid precursor protein

W. Fischer, Minkyu Park, E. Levy, 2007 .

Defective neurite extension is caused by a mutation in amyloid β/A4 (Aβ) protein precursor found in Familial Alzheimer's Disease

Ronald G. Thomas, S. Sisodia, D. Otero, 1997 .

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.

M. Yoshimoto, D. Otero, Y. Xia, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The Biological Function of Amyloid β/A4 Protein Precursor

E. Masliah, H. Ninomiya, D. Otero, 1994 .

NACP, the precursor protein of the non-amyloid 18/A4 protein (A18) component of Alzheimer disease amyloid, binds Af8 and stimulates Af3 aggregation

M. Yoshimoto, D. Otero, Akihiko IWAIt, 2005 .

From differentiation to proliferation: the secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells.

C. Y. Chen, V. Herzog, C. Pietrzik, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Bacterial expression, purification, and functional mapping of the amyloid beta/A4 protein precursor.

N. Robakis, L. Refolo, D. Otero, 1992, The Journal of biological chemistry.

Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor.

E. Masliah, J M Roch, E Masliah, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Designing stable blood-brain barrier-permeable prosaptide peptides for treatment of central nervous system neurodegeneration.

W. Banks, J. O'brien, D. Otero, 2000, The Journal of pharmacology and experimental therapeutics.

Reversal of thermal hyperalgesia in a rat partial sciatic nerve ligation model by Prosaptide™ TX14(A)

J. O'brien, D. Otero, B. Conrad, 1999, Neuroscience Letters.

A retro-inverso Prosaptide D5 promotes a myelination process in developing rats.

C. Y. Wang, J. O'brien, D. Otero, 2001, Brain research. Developmental brain research.

Prosaptide™ D5 reverses hyperalgesia: inhibition of calcium channels through a pertussis toxin-sensitive G-protein mechanism in the rat

J. O'brien, D. Otero, M. Hiraiwa, 2000, Neuroscience Letters.

Reduction of Neurological Damage by a Peptide Segment of the Amyloid β/A4 Protein Precursor in a Rabbit Spinal Cord Ischemia Model

E. Masliah, J. Zivin, D. Otero, 1994, Experimental Neurology.

Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease.

R. Thomas, S. Sisodia, D. Otero, 1997, Journal of neurobiology.

Proteins that bind to the RERMS region of beta amyloid precursor protein.

W. Fischer, Minkyu Park, E. Levy, 2007, Biochemical and Biophysical Research Communications - BBRC.

Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

E. Masliah, D. Otero, D. Schubert, 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth

H. Ninomiya, D. Otero, T. Saitoh, 1993, The Journal of cell biology.