Hideo Iwaï

发表

A monomeric TIM-barrel structure from Pyrococcus furiosus is optimized for extreme temperatures.

P. Heikinheimo, H. Repo, J. S. Oeemig, 2012, Acta crystallographica. Section D, Biological crystallography.

Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR

I. Shimada, Takumi Ueda, Hideo Iwaï, 2017, Scientific Reports.

I-TASSER: a unified platform for automated protein structure and function prediction

R. Sharan, A. Tanay, Chaim Linhart, 2010, Nature Protocols.

Structural basis for protein trans‐splicing by a bacterial intein‐like domain – protein ligation without nucleophilic side chains

J. S. Oeemig, Hideo Iwaï, A. Aranko, 2013, The FEBS journal.

Hidden photoinduced reactivity of the blue fluorescent protein mKalama1.

S. Pletnev, A. Bommarius, Russell B. Vegh, 2015, Physical chemistry chemical physics : PCCP.

Segmental isotopic labeling by asparaginyl endopeptidase-mediated protein ligation

A. Plückthun, Hideo Iwaï, K. Mikula, 2018, Journal of Biomolecular NMR.

Convergent evolution of the Hedgehog/Intein fold in protein splicing

Salla I. Virtanen, Hannes M. Beyer, A. Wlodawer, 2020, bioRxiv.

The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms

Salla I. Virtanen, Hannes M. Beyer, A. Wlodawer, 2020, International journal of molecular sciences.

The Inducible Intein-Mediated Self-Cleaving Tag (IIST) System: A Novel Purification and Amidation System for Peptides and Proteins

Hideo Iwaï, A. S. Aranko, 2021, Molecules.

Segmental isotopic labeling of a 140 kDa dimeric multi-domain protein CheA from Escherichia coli by expressed protein ligation and protein trans-splicing

I. Shimada, Takumi Ueda, Hideo Iwaï, 2012, Journal of biomolecular NMR.

Use of protein trans‐splicing to produce active and segmentally 2H, 15N labeled mannuronan C5‐epimerase AlgE4

F. Aachmann, S. Valla, G. Skjåk-Bræk, 2010, Protein science : a publication of the Protein Society.

NMR resonance assignment of DnaE intein from Nostoc punctiforme

J. S. Oeemig, Janica Djupsjöbacka, Hideo Iwaï, 2009, Biomolecular NMR assignments.

Segmental isotopic labeling of a single‐domain globular protein without any refolding step by an asparaginyl endopeptidase

I. Tascón, Hideo Iwaï, K. Mikula, 2017, FEBS letters.

Is coproporphyrin III a copper-acquisition compound in Paracoccus denitrificans?

Jani V Anttila, T. Haltia, M. Baumann, 2011, Biochimica et biophysica acta.

Tandem SUMO fusion vectors for improving soluble protein expression and purification.

Fernando Guerrero, A. Ciragan, Hideo Iwaï, 2015, Protein expression and purification.

Heterogeneous dynamics in partially disordered proteins.

Salla I. Virtanen, Samuli Ollila, O. H. S. Ollila, 2020, Physical chemistry chemical physics : PCCP.

Biosynthesis of the bis-prenylated alkaloids muscoride A and B.

J. Yli-Kauhaluoma, K. Sivonen, J. Jokela, 2019, ACS chemical biology.

Improved molecular replacement by density- and energy-guided protein structure optimization

Randy J. Read, David Baker, Deborah Fass, 2011, Nature.

Segmental isotopic labeling of a central domain in a multidomain protein by protein trans-splicing using only one robust DnaE intein.

V. Dötsch, F. Bernhard, Hideo Iwaï, 2009, Angewandte Chemie.

Nature's recipe for splitting inteins.

A. Wlodawer, Hideo Iwaï, A. S. Aranko, 2014, Protein engineering, design & selection : PEDS.

PTCHD1 Binds Cholesterol but Not Sonic Hedgehog, Suggesting a Distinct Cellular Function

A. Goldman, D. S. Gkotsi, Hideo Iwaï, 2023, International journal of molecular sciences.

Mini-Intein Structures from Extremophiles Suggest a Strategy for Finding Novel Robust Inteins

Hannes M. Beyer, Hideo Iwaï, Mimmu K. Hiltunen, 2021, Microorganisms.

Substrate specificities of inteins investigated by QuickDrop‐cassette mutagenesis

Hannes M. Beyer, J. S. Oeemig, Hideo Iwaï, 2020, FEBS letters.

The crystal structure of the naturally split gp41‐1 intein guides the engineering of orthogonal split inteins from cis‐splicing inteins

Hannes M. Beyer, A. Wlodawer, Mi Li, 2020, The FEBS journal.

The crystal structure of the naturally split gp41-1 intein guides the engineering of orthogonal split inteins from a cis-splicing intein

Hannes M. Beyer, A. Wlodawer, Mi Li, 2019, bioRxiv.

NMR and crystal structures of the Pyrococcus horikoshii RadA intein guide a strategy for engineering a highly efficient and promiscuous intein.

Alexander Wlodawer, Tommi Kajander, A. Wlodawer, 2012, Journal of molecular biology.

Protein trans-splicing and its use in structural biology: opportunities and limitations.

Hideo Iwaï, Gerrit Volkmann, Hideo Iwaï, 2010, Molecular bioSystems.

Solution structure of DnaE intein from Nostoc punctiforme: Structural basis for the design of a new split intein suitable for site‐specific chemical modification

J. S. Oeemig, Janica Djupsjöbacka, Hideo Iwaï, 2009, FEBS letters.

In Vivo and In Vitro Protein Ligation by Naturally Occurring and Engineered Split DnaE Inteins

E. Buchinger, S. Züger, Hideo Iwaï, 2009, PloS one.

Structural Basis for Complement Evasion by Lyme Disease Pathogen Borrelia burgdorferi □S

A. Goldman, T. Meri, T. Kajander, 2022 .

Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA

M. Frilander, Hideo Iwaï, H. Heikkinen, 2018, RNA.

Crystal structures of CDC21-1 inteins from hyperthermophilic archaea reveal the selection mechanism for the highly conserved homing endonuclease insertion site

Hannes M. Beyer, Hideo Iwaï, T. Kudling, 2019, Extremophiles.

Structural Basis for the Persistence of Homing Endonucleases in Transcription Factor IIB Inteins.

Alexander Wlodawer, Mi Li, A. Wlodawer, 2017, Journal of molecular biology.

Structure-based engineering and comparison of novel split inteins for protein ligation.

A. Wlodawer, T. Kajander, J. S. Oeemig, 2014, Molecular bioSystems.

Mutations in the U 11 / U 1265 K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U 12 snRNA

M. Frilander, Hideo Iwaï, H. Heikkinen, 2018 .

Rotational Dynamics of Proteins from Spin Relaxation Times and Molecular Dynamics Simulations

O. H. S. Ollila, Hideo Iwaï, H. Heikkinen, 2018, The journal of physical chemistry. B.

Conformational dynamics are a key factor in signaling mediated by the receiver domain of a sensor histidine kinase from Arabidopsis thaliana

L. Žídek, Milan Zachrdla, Z. Jaseňáková, 2017, The Journal of Biological Chemistry.

Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR

I. Shimada, T. Mizukoshi, Takumi Ueda, 2018, Nature Communications.

Structural Basis for the Propagation of Homing Endonuclease-Associated Inteins

Hannes M. Beyer, Hideo Iwaï, 2022, Frontiers in Molecular Biosciences.

Tying up the Loose Ends: A Mathematically Knotted Protein

A. Goldman, S. Hsu, I. Tascón, 2021, Frontiers in Chemistry.

Salt-inducible Protein Splicing in cis and trans by Inteins from Extremely Halophilic Archaea as a Novel Protein-Engineering Tool.

I. Tascón, Hideo Iwaï, A. Ciragan, 2016, Journal of molecular biology.

Segmental isotopic labeling of a 140 kDa dimeric multi-domain protein CheA from Escherichia coli by expressed protein ligation and protein trans-splicing

I. Shimada, Takumi Ueda, Hideo Iwaï, 2012, Journal of biomolecular NMR.

Cloning, expression, purification, crystallization and preliminary X-ray diffraction data of the Pyrococcus horikoshii RadA intein.

David Baker, Frank DiMaio, Alexander Wlodawer, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Evaluation and comparison of protein splicing by exogenous inteins with foreign exteins in Escherichia coli

Simo Ellilä, Hideo Iwaï, Jaana M. Jurvansuu, 2011, FEBS letters.

Editorial: Chemical Biology Tools for Peptide and Protein Research

Y. Tsai, Hideo Iwaï, K. Pors, 2022, Frontiers in Chemistry.

Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR

I. Shimada, Takumi Ueda, Hideo Iwaï, 2017, Scientific Reports.

Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR

I. Shimada, T. Mizukoshi, Takumi Ueda, 2018, Nature Communications.

Intermolecular domain swapping induces intein-mediated protein alternative splicing.

T. Kajander, H. Iwai, J. S. Oeemig, 2013, Nature chemical biology.

NMR Structure Determinations of Small Proteins Using only One Fractionally 20% 13C- and Uniformly 100% 15N-Labeled Sample

Hideo Iwaï, H. Heikkinen, S. M. Backlund, 2021, Molecules.

Segmental isotopic labeling by asparaginyl endopeptidase-mediated protein ligation

A. Plückthun, Hideo Iwaï, K. Mikula, 2018, Journal of biomolecular NMR.

Segmental isotopic labeling of multi-domain and fusion proteins by protein trans-splicing in vivo and in vitro

Hideo Iwaï, M. Muona, Vytas Raulinaitis, 2010, Nature Protocols.

Structural Basis for Complement Evasion by Lyme Disease Pathogen Borrelia burgdorferi

A. Goldman, T. Meri, T. Kajander, 2013, The Journal of Biological Chemistry.

An Off-the-Shelf Approach for the Production of Fc Fusion Proteins by Protein Trans-Splicing towards Generating a Lectibody In Vitro

Hideo Iwaï, Gerrit Volkmann, Anniina Jaakkonen, 2020, International journal of molecular sciences.

Simulation of Energy Distribution for Scanning X‐ray Probe

M. Kudo, Hideo Iwaï, P. E. Larson, 1997 .

NMR Structure and Dynamics of TonB Investigated by Scar-Less Segmental Isotopic Labeling Using a Salt-Inducible Split Intein

Hannes M. Beyer, A. Ciragan, Hideo Iwaï, 2020, Frontiers in Chemistry.

Off‐Pathway‐Sensitive Protein‐Splicing Screening Based on a Toxin/Antitoxin System

Hannes M. Beyer, Hideo Iwaï, 2019, Chembiochem : a European journal of chemical biology.

Solution structure of DnaE intein from Nostoc punctiforme: Structural basis for the design of a new split intein suitable for site‐specific chemical modification

J. S. Oeemig, Janica Djupsjöbacka, Hideo Iwaï, 2009, FEBS letters.