C. Bird

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A Common Fold Mediates Vertebrate Defense and Bacterial Attack

Ashley M Buckle, Corrine J Porter, James C Whisstock, 2007, Science.

Expression and purification of recombinant human granzyme B from Pichia pastoris.

J. Whisstock, P. Bird, Jiuru Sun, 1999, Biochemical and biophysical research communications.

A Novel Serpin Regulatory Mechanism

P. Bird, P. Thompson, D. Kaiserman, 2015, The Journal of Biological Chemistry.

Proteinase Inhibitor 6 Cannot Be Secreted, Which Suggests It Is a New Type of Cellular Serpin (*)

P. Bird, J. Hayman, P. Coughlin, 1996, The Journal of Biological Chemistry.

Selective Regulation of Apoptosis: the Cytotoxic Lymphocyte Serpin Proteinase Inhibitor 9 Protects against Granzyme B-Mediated Apoptosis without Perturbing the Fas Cell Death Pathway

J. Trapani, Sharad Kumar, P. Bird, 1998, Molecular and Cellular Biology.

The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses.

P. Bird, P. Hosking, C. Hirst, 2001, Cellular immunology.

Characterization of the mouse thrombomodulin gene and functional analysis of the 5' flanking region in F9 teratocarcinoma cells.

C. Bird, P. Bird, P. Niforas, 1993, Biochimica et biophysica acta.

Cationic Sites on Granzyme B Contribute to Cytotoxicity by Promoting Its Uptake into Target Cells

J. Whisstock, J. Trapani, P. Bird, 2005, Molecular and Cellular Biology.

Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain

P. Bird, C. Bird, M. Teasdale, 1994, Immunology and cell biology.

Extracellular Matrix Remodeling by Human Granzyme B via Cleavage of Vitronectin, Fibronectin, and Laminin*

J. Trapani, E. Nice, P. Bird, 2005, Journal of Biological Chemistry.

Use of granzyme B-based fluorescent protein reporters to monitor granzyme distribution and granule integrity in live cells

P. Bird, M. Prescott, C. Bird, 2010, Biological chemistry.

Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation

Si Ming Man, J. Whisstock, M. Pellegrini, 2022, Immunology and cell biology.

facilitate rapid access of granzymes during killer cell attack Perforin forms transient pores on the target cell plasma membrane to

J. Whisstock, H. Saibil, J. Trapani, 2013 .

Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement

P. Bird, M. Prakash, C. Bird, 2009, Immunology and cell biology.

Immunodetection of granzyme B tissue distribution and cellular localisation.

P. Bird, M. Prescott, C. Bird, 2012, Methods in molecular biology.

Granzyme B Encoded by the Commonly Occurring Human RAH Allele Retains Pro-apoptotic Activity*

J. Trapani, P. Bird, Jiuru Sun, 2004, Journal of Biological Chemistry.

Overexpression Enhances CTL Potency Effector Cell Degranulation, and Its During Accessory Cell Maturation and Proteinase Inhibitor 9, Is Up-Regulated The Intracellular Granzyme B Inhibitor,

P. Bird, P. Ashton‐Rickardt, C. Hirst, 2002 .

Serpinb9 (Spi6)‐deficient mice are impaired in dendritic cell‐mediated antigen cross‐presentation

P. Bird, J. Mintern, J. Villadangos, 2012, Immunology and cell biology.

Immunobiology of the serine protease allergens from house dust mites.

P. Thompson, G. Stewart, C. Bird, 1994, American journal of industrial medicine.

Do the group II dust mite allergens correspond to lysozyme?

P. Thompson, G. Stewart, C. Bird, 1992, The Journal of allergy and clinical immunology.

Granzyme K‐deficient mice show no evidence of impaired antiviral immunity

M. Pellegrini, P. Bird, C. Allison, 2017, Immunology and cell biology.

Turnover of Thrombomodulin at the Cell Surface Occurs at a Similar Rate to Receptors that Are Not Actively Internalized

P. Bird, C. Bird, M. Teasdale, 1998, Thrombosis and Haemostasis.

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack.

Helen R Saibil, Olivia Susanto, James C Whisstock, 2013, Blood.

A New Family of 10 Murine Ovalbumin Serpins Includes Two Homologs of Proteinase Inhibitor 8 and Two Homologs of the Granzyme B Inhibitor (Proteinase Inhibitor 9)*

J. Trapani, P. Bird, Jiuru Sun, 1997, The Journal of Biological Chemistry.

The major human and mouse granzymes are structurally and functionally divergent

James C. Whisstock, Philip E. Thompson, Dion Kaiserman, 2006, The Journal of cell biology.

Maspin is not required for embryonic development or tumour suppression

J. Whisstock, R. Law, P. Bird, 2014, Nature Communications.

A Cytosolic Granzyme B Inhibitor Related to the Viral Apoptotic Regulator Cytokine Response Modifier A Is Present in Cytotoxic Lymphocytes*

L. McDonald, J. Trapani, P. Bird, 1996, The Journal of Biological Chemistry.

The granzyme B-Serpinb9 axis controls the fate of lymphocytes after lysosomal stress

P. Bird, M. Smyth, N. Waterhouse, 2014, Cell Death and Differentiation.

Association of annexin V with mitochondria

P. Bird, Jiuru Sun, C. Bird, 1993, FEBS letters.

Nucleocytoplasmic Distribution of the Ovalbumin Serpin PI-9 Requires a Nonconventional Nuclear Import Pathway and the Export Factor Crm1

P. Bird, D. Jans, Jiuru Sun, 2001, Molecular and Cellular Biology.

The Intracellular Granzyme B Inhibitor, Proteinase Inhibitor 9, Is Up-Regulated During Accessory Cell Maturation and Effector Cell Degranulation, and Its Overexpression Enhances CTL Potency1

P. Bird, P. Ashton‐Rickardt, C. Hirst, 2003, The Journal of Immunology.

A pro‐survival role for the intracellular granzyme B inhibitor Serpinb9 in natural killer cells during poxvirus infection

P. Bird, M. Prakash, K. L. Scarff, 2017, Immunology and cell biology.

The intracellular serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G.

S. Bottomley, P. Bird, C. Hirst, 1999, Blood.

Serpinb9 (Spi6)‐deficient mice are impaired in dendritic cell‐mediated antigen cross‐presentation

P. Bird, J. Mintern, J. Villadangos, 2012 .

Targeted Disruption of SPI3/Serpinb6 Does Not Result in Developmental or Growth Defects, Leukocyte Dysfunction, or Susceptibility to Stroke

P. Bird, P. Crack, H. Nandurkar, 2004, Molecular and Cellular Biology.

Analysis of Perforin Assembly by Quartz Crystal Microbalance Reveals a Role for Cholesterol and Calcium-independent Membrane Binding*

S. E. Stewart, J. Whisstock, J. Trapani, 2015, The Journal of Biological Chemistry.

The major human and mouse granzymes are structurally and functionally divergent

J. Whisstock, J. Trapani, P. Bird, 2006, The Journal of cell biology.