O. Minowa

发表

Hydrogen bonding in the carboxyl-terminal half-fragment 78-148 of calmodulin as studied by two-dimensional nuclear magnetic resonance.

M. Ikura, K. Hikichi, O. Minowa, 1985, Biochemistry.

Negative Regulation of BMP/Smad Signaling by Tob in Osteoblasts

Sakae Tanaka, T. Noda, K. Miyazono, 2000, Cell.

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

T Takahashi, T. Noda, K. Miyazono, 2001, EMBO reports.

Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.

S. Wakana, T. Noda, Y. Gondo, 2016, Biochemical and biophysical research communications.

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

Steve D. M. Brown, N. Karp, J. Mason, 2017, Nature Communications.

G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo.

T. Noda, H. Takano, J. Kuno, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice.

H. Aburatani, H. Takano, T. Arai, 2000, Proceedings of the National Academy of Sciences of the United States of America.

High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress.

T. Noda, T. Arai, V. Kelly, 2002, Carcinogenesis.

Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA.

T. Noda, T. Arai, V. Kelly, 2003, Cancer research.

cDNA cloning and genomic organization of the mouse BMP type II receptor.

K. Miyazono, H. Beppu, M. Kawabata, 1997, Biochemical and biophysical research communications.

Late-onset hearing loss in a mouse model of DFN3 non-syndromic deafness: morphologic and immunohistochemical analyses

T. Noda, Y. Katori, T. Oshima, 2002, Hearing Research.

Successful germ-line transmission of chimeras generated by coculture aggregation with J1 ES cells and eight-cell embryos.

S. Inoue, J. Kuno, M. Muramatsu, 1999, Analytical biochemistry.

Novel mouse model for Gardner syndrome generated by a large‐scale N‐ethyl‐N‐nitrosourea mutagenesis program

H. Masuya, S. Wakana, T. Noda, 2013, Cancer science.

Osteoporotic bone formation in mice lacking tob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation

Sakae Tanaka, T. Noda, M. Noda, 2008, FEBS letters.

ABBREVIATIONS MODY : maturation onset diabetes mellitus of the young MODY 2 : maturation onset diabetes mellitus of the young

H. Masuya, S. Wakana, T. Noda, 2004 .

The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA.

T. Noda, T. Arai, V. Kelly, 2006, Toxicology.

Carcinogenicity of dimethylarsinic acid in Ogg1‐deficient mice

T. Noda, S. Fukushima, A. Kinoshita, 2007, Cancer science.

Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors

H. Masuya, S. Wakana, T. Noda, 2014, Cancer science.

Crucial roles of Brn1 in distal tubule formation and function in mouse kidney

T. Noda, S. Ito, K. Jishage, 2003, Development.

Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness

T. Noda, K. Ikeda, O. Minowa, 2014, PloS one.

Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center.

Hiroshi Masuya, Kazunori Waki, Tetsuo Noda, 2009, Experimental animals.

A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice

Tetsuo Noda, Okio Hino, Osamu Minowa, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

Tetsuo Noda, Yoshihiko Uehara, Kohei Shiota, 1995, Nature.

Implementation of the modified-SHIRPA protocol for screening of dominant phenotypes in a large-scale ENU mutagenesis program

Hiroshi Masuya, Tetsuo Noda, Toshihiko Shiroishi, 2005, Mammalian Genome.

Identification of Reliable Components in Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS): a Data-Driven Approach across Metabolic Processes

Jun Kikuchi, Tetsuo Noda, Maki Inoue, 2015, Scientific Reports.

Isozymes of isocitrate dehydrogenase from an obligately psychrophilic bacterium, Vibrio sp. strain ABE-1: purification, and modulation of activities by growth conditions.

N. Fukunaga, A. Ishii, Y. Mizuno, 1987, Journal of biochemistry.

Altered pain responses in mice lacking alpha 1E subunit of the voltage-dependent Ca2+ channel.

M. Osanai, Y. Matsuda, H. Saegusa, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Zic2 regulates the kinetics of neurulation.

K. Mikoshiba, J. Aruga, T. Nagai, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Role of CCK-A Receptor for Pancreatic Function in Mice: A Study in CCK-A Receptor Knockout Mice

T. Noda, Tomoko Kobayashi, S. Kanai, 2002, Pancreas.

Binding and transcriptional activation of the promoter for the neural cell adhesion molecule by HoxC6 (Hox-3.3).

G. Edelman, E. D. De Robertis, O. Minowa, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Altered pain responses in mice lacking a 1 E subunit of the voltage-dependent Ca 2 1 channel

M. Osanai, Y. Matsuda, H. Saegusa, 2000 .

Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness.

T. Noda, T. Noda, T. Sugimoto, 1999, Science.

Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.

S. Inoue, J. Kuno, M. Muramatsu, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Divalent cation binding to wheat germ calmodulin.

M. Yoshida, K. Yagi, O. Minowa, 1983, Journal of biochemistry.

Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice

T. Noda, T. Anzai, K. Ikeda, 2015, PloS one.

Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.

T. Noda, K. Ikeda, Masaaki Suzuki, 2015, Human molecular genetics.

Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.

T. Noda, S. Ito, T. Fujita, 2014, Immunity.

Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons.

Tetsuo Noda, Masaharu Ogawa, Hitoshi Kawano, 2002, Genes & development.

BMP type II receptor is required for gastrulation and early development of mouse embryos.

K. Miyazono, H. Beppu, M. Kawabata, 2000, Developmental biology.

Mouse models for ROS1-fusion-positive lung cancers and their application to the analysis of multikinase inhibitor efficiency.

T. Noda, S. Mori, Y. Gondo, 2016, Carcinogenesis.

Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.

T. Noda, J. Kuno, T. Kobayashi, 1999, Cancer research.

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice.

T. Noda, M. Shibuya, J. Kuno, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Molecular characterization of ENU mouse mutagenesis and archives.

H. Masuya, S. Wakana, Y. Sakaki, 2005, Biochemical and biophysical research communications.

Altered pain responses in mice lacking α1E subunit of the voltage-dependent Ca2+ channel

M. Osanai, Y. Matsuda, H. Saegusa, 2000 .

Excitation-contraction uncoupling and muscular degeneration in mice lacking functional skeletal muscle ryanodine-receptor gene

T. Noda, H. Takano, J. Kuno, 1994, Nature.

Purification and characterization of α1-thiol proteinase inhibitor and its identity with kinin and fragment 1.2 free high molecular weight kininogen

S. Higashiyama, I. Ohkubo, Y. Mizuno, 1988 .

A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program.

Hiroshi Masuya, Tomohiro Suzuki, Masato Kasuga, 2004, Human molecular genetics.

Mouse Zic1 Is Involved in Cerebellar Development

K. Mikoshiba, T. Noda, J. Kuno, 1998, The Journal of Neuroscience.

Mice Mutation in Tsc 2 Embryonic Lethality Caused by a GermLine Renal Carcinogenesis , Hepatic Hemangiomatosis , and Updated

T. Noda, J. Kuno, O. Hino, 1999 .

Assembly of the cochlear gap junction macromolecular complex requires connexin 26.

T. Noda, S. Yum, T. Sakurai, 2014, The Journal of clinical investigation.

Functional expression of microsomal and mitochondrial cytochrome P-450 (d and SCC) in COS-7 cells from cloned cDNA.

Y. Fujii‐Kuriyama, K. Sogawa, Y. Higashi, 1990, Cell structure and function.

Sequence‐specific assignments of downfield‐shifted amide proton resonances of calmodulin Use of two‐dimensional NMR analysis of its tryptic fragments

Mitsuhiko Ikura, Osamu Minowa, M. Ikura, 1987 .

Calcium binding to tryptic fragments of calmodulin.

K. Yagi, O Minowa, O. Minowa, 1984, Journal of biochemistry.

Significance of domain structure of calmodulin on the activation of Ca2+-calmodulin-regulated enzymes.

M. Ikura, K. Yagi, K. Hikichi, 1988, Advances in second messenger and phosphoprotein research.

Nuclear magnetic resonance studies on calmodulin: calcium-dependent spectral change of proteolytic fragments

M. Ikura, K. Yagi, K. Hikichi, 1984 .

In Vitro Models of GJB2-Related Hearing Loss Recapitulate Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea

T. Noda, K. Ikeda, O. Minowa, 2016, Stem cell reports.

N-terminal region (domain 1) of calmodulin is the low affinity site for Ca2+. A 13C NMR study of S-cyanocalmodulin.

M. Ikura, K. Yagi, K. Hikichi, 1984, Journal of biochemistry.

The primary structure of two molecular species of porcine organ-common type acylphosphatase.

Y. Mizuno, O. Minowa, Y. Kanesaka, 1991, Journal of Biochemistry (Tokyo).

The primary structure of chicken muscle acylphosphatase isozyme Ch2.

Y. Mizuno, O. Minowa, Y. Ohba, 1987, Journal of Biochemistry (Tokyo).

Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor

K. Mikoshiba, E. Nagata, M. Yamada, 1996, Nature.

Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice

T. Noda, T. Anzai, K. Ikeda, 2015, PloS one.

Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.

J. Kuno, O. Minowa, H. Hiroi, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.

T. Noda, K. Ikeda, Masaaki Suzuki, 2015, Human molecular genetics.