D. Tomlinson

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Identification of Changes in Gene Expression in Dorsal Root Ganglia in Diabetic Neuropathy: Correlation With Functional Deficits

A. Hayes, L. Zeef, Leanne Wardleworth, 2006, Journal of neuropathology and experimental neurology.

Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.

N. Calcutt, A. Verkhratsky, P. Fernyhough, 2003, Diabetes.

Aldose reductase inhibitors and their potential for the treatment of diabetic complications.

L. Diemel, D. Tomlinson, E. Stevens, 1994, Trends in pharmacological sciences.

Expression of neuropeptides in experimental diabetes; effects of treatment with nerve growth factor or brain-derived neurotrophic factor.

P. Fernyhough, L. Diemel, D. Tomlinson, 1994, Brain research. Molecular brain research.

Deficits in sciatic nerve neuropeptide content coincide with a reduction in target tissue nerve growth factor messenger RNA in streptozotocin-diabetic rats: Effects of insulin treatment

P. Fernyhough, L. Diemel, D. Tomlinson, 1994, Neuroscience.

Human Recombinant Nerve Growth Factor Replaces Deficient Neurotrophic Support in the Diabetic Rat

J. Hardy, P. Fernyhough, L. Diemel, 1995, The European journal of neuroscience.

Altered Neurotrophin mRNA Levels in Peripheral Nerve and Skeletal Muscle of Experimentally Diabetic Rats

P. Fernyhough, L. Diemel, D. Tomlinson, 1995, Journal of neurochemistry.

Role of Neurotrophins in Diabetic Neuropathy and Treatment with Nerve Growth Factors

P. Fernyhough, L. Diemel, D. Tomlinson, 1997, Diabetes.

Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy.

J. Priestley, P. Fernyhough, A. Gallagher, 1999, Diabetes.

Advanced Glycation End Products in Extracellular Matrix Proteins Contribute to the Failure of Sensory Nerve Regeneration in Diabetes

Paul J Thornalley, C. Streuli, N. Rabbani, 2009, Diabetes.

Angiotensin-converting enzyme inhibitors: are there credible mechanisms for beneficial effects in diabetic neuropathy?

R. Malik, D. Tomlinson, 2002, International review of neurobiology.

Diabetic neuropathies: components of etiology

N. Gardiner, D. Tomlinson, 2008, Journal of the peripheral nervous system : JPNS.

Preconditioning injury-induced neurite outgrowth of adult rat sensory neurons on fibronectin is mediated by mobilisation of axonal α5 integrin

M. Humphries, C. Streuli, P. Fernyhough, 2007, Molecular and Cellular Neuroscience.

Focally administered nerve growth factor suppresses molecular regenerative responses of axotomized peripheral afferents in rats

P. Fernyhough, D. Tomlinson, L. Mohiuddin, 1999, Neuroscience.

Fast orthograde axonal transport in sciatic motoneurones and nerve temperature in streptozotocin-diabetic rats

D. Tomlinson, J. Townsend, S. J. Whiteley, 1985, Diabetologia.

Neurotrophins and peripheral neuropathy.

P. Fernyhough, L. Diemel, D. Tomlinson, 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy

D. Horrobin, H. Tritschler, D. Tomlinson, 1998, Diabetologia.

A role for mitogen‐activated protein kinases in the etiology of diabetic neuropathy

A. Boulton, E. Jude, P. Fernyhough, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The influence of hypoxia on transvascular leakage in the isolated rat heart: quantitative and ultrastructural studies.

D. Tomlinson, B. Ward, H. A. Al-Haboubi, 1995, The Journal of physiology.

A method for the measurement of growth of noradrenergic axons in tissue culture and the effects of colchicine thereon

D. Tomlinson, A. Yusof, D. R. Tomlinson, 1980, The Histochemical Journal.

ON THE MECHANISM OF PANCURONIUM‐INDUCED SUPER‐SENSITIVITYTO NORADRENALINE IN RAT SMOOTH MUSCLE

D. Tomlinson, 1979, British journal of pharmacology.

THE MODE OF ACTION OF TETRABENAZINE ON PERIPHERAL NORADRENERGIC NERVES

D. Tomlinson, 1977, British journal of pharmacology.

Nerve growth factor treatment of adult rats selectively enhances innervation of urinogenital tract rather than vascular smooth muscle

G. Burnstock, P. Fernyhough, L. Diemel, 1995, International Journal of Developmental Neuroscience.

Neurotrophic factors in peripheral neuropathies: Pharmacological strategies

D. Tomlinson, S. Riaz, 1996, Progress in Neurobiology.

Neurogenic cutaneous vasodilatation and plasma extravasation in diabetic rats: effect of insulin and nerve growth factor

G. Bennett, S. Brain, L. Diemel, 1998, British journal of pharmacology.

Reversal of deficits in axonal transport and nerve conduction velocity by treatment of streptozotocin-diabetic rats with myo-inositol

D. Tomlinson, J. Mayer, 1985, Experimental Neurology.

Slow Component-a of Axonal Transport, Nerve myo-Inositol, and Aldose Reductase Inhibition in Streptozocin-Diabetic Rats

P. Sidenius, D. Tomlinson, Jørn Rolighed Larsen, 1986, Diabetes.

Expression of constitutive cyclo-oxygenase (COX-1) in rats with streptozotocin-induced diabetes; effects of treatment with evening primrose oil or an aldose reductase inhibitor on COX-1 mRNA levels.

C. Fang, D. Tomlinson, Z. Jiang, 1997, Prostaglandins, leukotrienes, and essential fatty acids.

Impaired nerve regeneration in streptozotocin-diabetic rats. Effects of treatment with an aldose reductase inhibitor

D. Tomlinson, P. Ekström, 1989, Journal of the Neurological Sciences.

Stimulation of nerve growth factor and substance P expression in the iris–trigeminal axis of diabetic rats—involvement of oxidative stress and effects of aldose reductase inhibition

P. Fernyhough, L. Diemel, D. Tomlinson, 1998, Brain Research.

Effect of nerve growth factor treatment on p75NTR gene expression in lumbar dorsal root ganglia of streptozocin-induced diabetic rats.

G. Michael, J. Priestley, P. Fernyhough, 1998, Diabetes.

Target tissue production and axonal transport of neurotrophin-3 are reduced in streptozotocin-diabetic rats

P. Fernyhough, L. Diemel, D. Tomlinson, 1998, Diabetologia.

Impaired Molecular Regenerative Responses in Sensory Neurones of Diabetic Rats: Gene Expression Changes in Dorsal Root Ganglia After Sciatic Nerve Crush

D. Tomlinson, L. Mohiuddin, 1997, Diabetes.

Regenerating sensory neurones of diabetic rats express reduced levels of mRNA for GAP-43, gamma-preprotachykinin and the nerve growth factor receptors, trkA and p75NGFR.

P. Fernyhough, D. Tomlinson, K. Maeda, 1996, Brain research. Molecular brain research.

Reduced Levels of mRNA Encoding Endoskeletal and Growth-Associated Proteins in Sensory Ganglia in Experimental Diabetes

P. Fernyhough, D. Tomlinson, L. Mohiuddin, 1995, Diabetes.

Effect of streptozotocin-induced diabetes on NGF, P75NTR and TrkA content of prevertebral and paravertebral rat sympathetic ganglia

R. Schmidt, C. Parvin, K. Roth, 2000, Brain Research.

Hypoxic neuropathy: relevance to human diabetic neuropathy

A. Boulton, E. Masson, R. Malik, 1990, Diabetologia.

The effect of tetrabenazine on the accumulation of noradrenaline in constricted postganglionic sympathetic nerves in vitro

D. Tomlinson, R. Till, D. Mayor, 1975, Cell and Tissue Research.

Effect of streptozotocin-diabetes on knee joint inflammation-induced changes in substance P and nerve growth factor in the rat.

S. Cruwys, B. Kidd, D. Tomlinson, 1996, Brain research. Molecular brain research.

Changes in preprotachykinin mRNA expression and substance P levels in dorsal root ganglia of monoarthritic rats: comparison with changes in synovial substance P levels

S. Cruwys, B. Kidd, D. Tomlinson, 1995, Brain Research.

Changes in sensory neuropeptides in dorsal root ganglion and spinal cord of spontaneously diabetic BB rats

J. Polak, G. Terenghi, A. Carrington, 1994, Acta Diabetologica.

Axonal transport of noradrenaline and noradrenergic transmission in rats with streptozotocin-induced diabetes

D. Tomlinson, K. Gillon, M. G. Smith, 1982, Diabetologia.

Axonal transport and tissue contents of substance P in rats with long-term streptozotocin-diabetes. Effects of the aldose reductase inhibitor ‘statil’

G. Willars, D. Tomlinson, P. Keen, 1987, Brain Research.

The effects of dietary treatment with essential fatty acids on sciatic nerve conduction and activity of the Na+/K+ pump in streptozotocin‐diabetic rats

D. Tomlinson, M. J. Lockett, 1992, British journal of pharmacology.

Resistance to hypoxic conduction block in sciatic nerves of rats with streptozotocin-induced diabetes mellitus

N. Calcutt, L. Diemel, A. Carrington, 1991, Journal of the Neurological Sciences.

Does Galactose Feeding Provide a Valid Model of Consequences of Exaggerated Polyol-Pathway Flux in Peripheral Nerve in Experimental Diabetes?

G. Willars, D. Tomlinson, J. Lambourne, 1987, Diabetes.

Deficient nitric oxide responsible for reduced nerve blood flow in diabetic rats: effects of L‐NAME, L‐arginine, sodium nitroprusside and evening primrose oil

P. Vo, N. Omawari, D. Tomlinson, 1996, British journal of pharmacology.

Coexistence of Nerve Conduction Deficit With Increased Na+-K+-ATPase Activity in Galactose-Fed Mice: Implications for Polyol Pathway and Diabetic Neuropathy

N. Calcutt, S. Biswas, D. Tomlinson, 1990, Diabetes.

Nerve growth factor and neurotrophin-3 enhance neurite outgrowth and up-regulate the levels of messenger RNA for growth-associated protein GAP-43 and Tα1 α-tubulin in cultured adult rat sensory neurones

P. Fernyhough, D. Tomlinson, L. Mohiuddin, 1995, Neuroscience Letters.

Neurotrophin-3 prevents the proximal accumulation of neurofilament proteins in sensory neurons of streptozocin-induced diabetic rats.

N. Calcutt, A. Mizisin, P. Fernyhough, 2003, Diabetes.

Elevated expression of neurotrophin-3 mRNA in sensory nerve of streptozotocin-diabetic rats

P. Fernyhough, D. Tomlinson, F. Cai, 1999, Neuroscience Letters.

Effect of sciatic nerve crush on local and target tissue production of neurotrophin-3 transcripts in rats

P. Fernyhough, D. Tomlinson, F. Cai, 1998, Neuroscience Letters.

Prostacyclin release in experimental diabetes: effects of evening primrose oil.

A. Carrington, D. Tomlinson, E. Stevens, 1993, Prostaglandins, leukotrienes, and essential fatty acids.

Aminoguanidine‐effects on endoneurial vasoactive nitric oxide and on motor nerve conduction velocity in control and streptozotocin‐diabetic rats

N. Omawari, D. Tomlinson, M. Dewhurst, 1997, British journal of pharmacology.

Essential fatty acid treatment — effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats

D. Tomlinson, P. Keen, A. M. Compton, 1989, Diabetologia.

Alternative Splicing of the Neurotrophin‐3 Gene Gives Rise to Different Transcripts in a Number of Human and Rat Tissues

P. Henttu, M. Yeo, D. Tomlinson, 2000, Journal of neurochemistry.

An appraisal of patient training for childbirth.

D. Tomlinson, W. Van Auken, 1953, American journal of obstetrics and gynecology.

Aldose Reductase Inhibitors and the Complications of Diabetes Mellitus

D. Tomlinson, 1993, Diabetic medicine : a journal of the British Diabetic Association.

Effects of aminoguanidine and N(G)-nitro-L-arginine methyl ester on vascular responses of aortae and lungs from streptozotocin-diabetic rats.

D. Tomlinson, M. Dewhurst, E. Stevens, 1997, Prostaglandins, leukotrienes, and essential fatty acids.

Neuritin Mediates Nerve Growth Factor–Induced Axonal Regeneration and Is Deficient in Experimental Diabetic Neuropathy

N. Gardiner, D. Tomlinson, Eugenia Karamoysoyli, 2008, Diabetes.

NGF-induced axonal regeneration and is deficient in experimental diabetic neuropathy

N. Gardiner, D. Tomlinson, Eugenia Karamoysoyli, 2007 .

The p75 neurotrophin receptor appears in plasma in diabetic rats—characterisation of a potential early test for neuropathy

L. Chilton, N. Gardiner, D. Tomlinson, 2004, Diabetologia.

Diabetic neuropathy, nerve growth factor and other neurotrophic factors

P. Fernyhough, L. Diemel, D. Tomlinson, 1994, Trends in Neurosciences.

Changes in nerve growth factor and preprotachykinin messenger RNA levels in the iris and trigeminal ganglion in diabetic rats; effects of treatment with insulin or nerve growth factor.

P. Fernyhough, L. Diemel, D. Tomlinson, 1995, Brain research. Molecular brain research.

VEGF-A and experimental diabetic neuropathy Engineered zinc finger protein mediated VEGF-A activation restores deficient VEGF-A in sensory neurons in experimental diabetes Running title: VEGF-A and experimental diabetic neuropathy

S. Spratt, R. Surosky, N. Gardiner, 2009 .

Effects of endothelin receptor antagonism with bosentan on peripheral nerve function in experimental diabetes

D. Tomlinson, E. Stevens, 1995, British journal of pharmacology.

A vitamin D3 derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats

M. Miller, M. Malcangio, D. Tomlinson, 1999, Diabetologia.

Myo-inositol and sorbitol metabolism in relation to peripheral nerve function in experimental diabetes in the rat: The effect of aldose reductase inhibition

J. Hawthorne, D. Tomlinson, K. Gillon, 1983, Diabetologia.

Polyols and myo-inositol in diabetic neuropathy--of mice and men.

D. Tomlinson, 1989, Mayo Clinic proceedings.

Enteric neuropeptides in streptozotocin-diabetic rats; effects of insulin and aldose reductase inhibition.

G. Burnstock, N. Calcutt, L. Diemel, 1996, Journal of the autonomic nervous system.

Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids

D. Tomlinson, Ç. Karasu, M. Dewhurst, 1995, Diabetologia.

Pharmacological modulation of nerve growth factor synthesis: a mechanistic comparison of vitamin D receptor and beta(2)-adrenoceptor agonists.

D. Tomlinson, S. Riaz, S. Samina Riaz, 2000, Brain research. Molecular brain research.

Central hypoxaemia in rats provokes neurological defects similar to those seen in experimental diabetes mellitus: Evidence for a partial role of endoneurial hypoxia in diabetic neuropathy

R. Leach, L. Diemel, D. Tomlinson, 1991, Neuroscience.

Expression of axotomy-inducible and apoptosis-related genes in sensory nerves of rats with experimental diabetes.

M. McElhaney, S. A. Price, D. Tomlinson, 2004, Brain research. Molecular brain research.

A vitamin D(3) derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats.

M. Miller, M. Malcangio, D. Tomlinson, 1999, Diabetologia.

Ketamine and Sympathetic Mechanisms in Cardiac and Smooth Muscle

A. J. Byrne, D. Tomlinson, T. Healy, 1982, Acta anaesthesiologica Scandinavica.

The Regeneration of Peripheral Noradrenergic Nerves after Chemical Sympathectomy in Diabetic Rats: Effects of Nerve Growth Factor

P. Vo, D. Tomlinson, 1999, Experimental Neurology.

An ultrastructural examination of the action of vinblastine on microtubules, neurofilaments and muscle filaments in vitro

D. Tomlinson, T. Bennett, 1976, Cell and Tissue Research.

Microtubules and the intra-axonal transport of noradrenaline storage (densecored) vesicles.

D. Tomlinson, P. Mráz, P. Banks, 1972, Journal of anatomy.

Further evidence for the involvement of microtubules in the intra‐axonal movement of noradrenaline storage granules

D. Tomlinson, P. Banks, D. Mayor, 1971, The Journal of physiology.

Studies on the translocation of noradrenaline‐containing vesicles in post‐ganglionic sympathetic neurones in vitro. Inhibition of movement by colchicine and vinblastine and evidence for the involvement of axonal microtubules

D. Tomlinson, M. Mitchell, P. Banks, 1971, The Journal of physiology.

Pulmonary responses of salbutamol tolerant guinea-pigs to aminophylline and ipratropium bromide.

D. Tomlinson, M. Ward, 1984, European journal of pharmacology.

The effects of guanethidine, bretylium and debrisoquine on the accumulation of noradrenaline in constricted postganglionic sympathetic nerves in vitro.

D. Tomlinson, D. Mayor, 1973, European journal of pharmacology.

Reduced anterograde and retrograde accumulation of axonally transported phosphofructokinase in streptozotocin-diabetic rats: effects of insulin and the aldose reductase inhibitor ‘Statil’

N. Calcutt, G. Willars, D. Tomlinson, 1987, Diabetologia.

Clenbuterol stimulates neurotrophic support in streptozotocin‐diabetic rats

D. Tomlinson, S. Riaz, D. Tomlinson, 1999, Diabetes, obesity & metabolism.

The pharmacology of diabetic neuropathy.

D. Tomlinson, David R. Tomlinson, 1992, Diabetes/metabolism reviews.

Impaired nerve regeneration in streptozotocin-diabetic rats is improved by treatment with gangliosides

D. Tomlinson, P. Ekström, 1990, Experimental Neurology.

α7 integrin mediates neurite outgrowth of distinct populations of adult sensory neurons

C. Streuli, P. Fernyhough, H. Mark, 2005, Molecular and Cellular Neuroscience.

Nerve Growth Factor- and Neurotrophin-3-Induced Changes in Nociceptive Threshold and the Release of Substance P from the Rat Isolated Spinal Cord

S. Cruwys, M. Malcangio, D. Tomlinson, 1997, The Journal of Neuroscience.

Effects of experimental diabetes on axonal and Schwann cell changes in sciatic nerve isografts.

L. Eckersley, D. Tomlinson, A. Ansselin, 2001, Brain research. Molecular brain research.

Aldose reductase inhibition with imirestat — effects on impulse conduction and insulin-stimulation of Na+/K+-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats

N. Calcutt, A. Carrington, D. Tomlinson, 1991, Diabetologia.

Effects of treatment with myo-inositol or its 1,2,6-trisphosphate (PP56) on nerve conduction in streptozotocin-diabetes.

N. Calcutt, A. Carrington, D. Tomlinson, 1993, European journal of pharmacology.

Increased resistance to hypoxic conduction block in sciatic nerves of diabetic rats: effects of extracellular glucose concentration and of aldose reductase inhibition.

A. Carrington, D. Tomlinson, C. Ettlinger, 1994, Journal of diabetes and its complications.

Depletion of substance P and calcitonin gene-related peptide in sciatic nerve of rats with experimental diabetes; effects of insulin and aldose reductase inhibition

G. Willars, L. Diemel, D. Tomlinson, 1992, Neuroscience Letters.

Prevention and Reversal of Defective Axonal Transport and Motor Nerve Conduction Velocity In Rats with Experimental Diabetes by Treatment with the Aldose Reductase Inhibitor Sorbinil

R. J. Moriarty, D. Tomlinson, J. Mayer, 1984, Diabetes.

Does neuropathy develop in animal models?

D. Tomlinson, L. Hounsom, 1997, Clinical neuroscience.

Statil-sensitive polyol formation in nerve of galactose-fed mice.

N. Calcutt, G. Willars, D. Tomlinson, 1988, Metabolism: clinical and experimental.

Two populations or granular vesicles in constricted post‐ganglionic sympathetic nerves.

D. Tomlinson, 1975, The Journal of physiology.

Acidic fibroblast growth factor enhances neurite outgrowth and stimulates expression of GAP-43 and Tα1 α-tubulin in cultured neurones from adult rat dorsal root ganglia

P. Fernyhough, D. Tomlinson, L. Mohiuddin, 1996, Neuroscience Letters.

A novel modification of the isolated perfused heart preparation [proceedings].

A. H. Short, D. Tomlinson, G. F. Sharpe, 1978, British journal of pharmacology.

Do endogenous prostaglandins modulate noradrenergic transmission in the rat isolated perfused vas deferens?

D. Tomlinson, 1980, Medical biology.

A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats

M. Malcangio, D. Tomlinson, 1998, Pain.

Glucose neurotoxicity

N. Gardiner, D. Tomlinson, 2008, Nature Reviews Neuroscience.

α-Lipoic acid corrects neuropeptide deficits in diabetic rats via induction of trophic support

M. Malcangio, D. Tomlinson, M. Dewhurst, 1997, Neuroscience Letters.

Substance P levels in peripheral nerve, skin, atrial myocardium and gastrointestinal tract of rats with long-term diabetes mellitus Effects of aldose reductase inhibition

N. Calcutt, G. Willars, D. Tomlinson, 1989, Journal of the Neurological Sciences.

Aldose reductase inhibitors and diabetic complications.

G. Willars, A. Carrington, D. Tomlinson, 1992, Pharmacology & therapeutics.

Neutrophil Sorbitol Production Impairs Oxidative Killing in Diabetes

D. Tomlinson, W. G. Reeves, R. Wilson, 1987, Diabetic medicine : a journal of the British Diabetic Association.

Response and cosmetic outcome of two fractionation regimens for AIDS-related Kaposi's sarcoma.

K. Harrington, D. Tomlinson, M. Harrison, 1998, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Streptozotocin-induced diabetes decreases substance P levels in experimental arthritis in the rat knee

S. Cruwys, B. Kidd, D. Tomlinson, 1995, Neuroscience Letters.

Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones

P. Fernyhough, R. Lindsay, G. Willars, 1993, Brain Research.

NMDA receptor activation modulates evoked release of substance P from rat spinal cord

M. Malcangio, D. Tomlinson, K. Fernandes, 1998, British journal of pharmacology.

Spinal effects of chronic intrathecal administration of the thyrotrophin-releasing hormone analogue (CG 3509) in rats

C. Marsden, K. Fone, D. Tomlinson, 1988, Brain Research.

Selective noradrenergic denervation of the heart following intravenous injections of vinblastine or vincristine

S. Gardiner, T. Bennett, D. Tomlinson, 1976, Naunyn-Schmiedeberg's Archives of Pharmacology.

Mitogen-activated protein kinases as glucose transducers for diabetic complications

D. Tomlinson, 1999, Diabetologia.

Effects of sorbinil treatment in rats with chronic streptozotocin-diabetes; changes in lens and in substance P and catecholamines in the iris.

N. Calcutt, I. Macdonald, G. Willars, 1989, Current eye research.

Studies on peripheral nerve and lens in long-term experimental diabetes: effects of the aldose reductase inhibitor statil.

G. Willars, D. Tomlinson, A. M. Compton, 1988, Metabolism: clinical and experimental.

Deficient Axonal Transport of Substance P in Streptozocin-Induced Diabetic Rats: Effects of Sorbinil and Insulin

G. Willars, D. Tomlinson, P. Keen, 1988, Diabetes.

Gene Transfer of an Engineered Transcription Factor Promoting Expression of VEGF-A Protects Against Experimental Diabetic Neuropathy

Lei Zhang, E. Rebar, P. Gregory, 2006, Diabetes.

SOME MISCELLANEOUS EXPERIMENTS WITH COCONUT EMBRYO CULTURE

D. Tomlinson, W. K. Thompson, R. Ashburner, 1996 .

A Guide to the Zygotic Embryo Culture of Coconut Palms (Cocos nucifera L.)

G. R. Ashburner, D. Tomlinson, W. K. Thompson, 1995 .

The structural effect of systemic NGF treatment on permanently axotomised dorsal root ganglion cells in adult rats

J. Jakobsen, L. Diemel, S. Vestergaard, 1999, Journal of anatomy.

Targeted Delivery of Nerve Growth Factor via Fibronectin Conduits Assists Nerve Regeneration in Control and Diabetic Rats

Robert A. Brown, G. Terenghi, C. Green, 1995, The European journal of neuroscience.

Motor nerve conduction velocity and nerve polyols in mice with short-term genetic or streptozotocin-induced diabetes

D. Tomlinson, S. J. Whiteley, 1985, Experimental Neurology.

Effects of adrenergic stimulation on sciatic nerve blood flow in diabetic and control rats.

P. Vo, D. Tomlinson, 1997, European journal of pharmacology.

Essential fatty acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus

A. Carrington, D. Tomlinson, E. Stevens, 1993, Diabetologia.

Nerve ischaemia in diabetic rats: time-course of development, effect of insulin treatment plus comparison of streptozotocin and BB models

A. Carrington, D. Tomlinson, E. Stevens, 2004, Diabetologia.

Aminoguanidine-e ects on endoneurial vasoactive nitric oxide and on motor nerve conduction velocity in control and streptozotocin-diabetic rats

N. Omawari, D. Tomlinson, M. Dewhurst, 1997 .

Insulin partially reverses deficits in peripheral nerve blood flow and conduction in experimental diabetes

G. Biessels, W. Gispen, D. Tomlinson, 1996, Journal of the Neurological Sciences.

The effects of ketamine on noradrenergic transmission and the response to noradrenaline in rat smooth muscle [proceedings].

A. J. Byrne, D. Tomlinson, T. Healy, 1979, British journal of pharmacology.

Selective effects of NGF treatment of adult rats 395

G. Burnstock, P. Fernyhough, L. Diemel, 2019 .

Brain-Derived Neurotrophic Factor mRNA Levels Are Up-Regulated in Hindlimb Skeletal Muscle of Diabetic Rats: Effect of Denervation

P. Fernyhough, D. Tomlinson, K. Maeda, 1996, Experimental Neurology.

Neurotrophin-3 reverses nerve conduction velocity deficits in streptozotocin-diabetic rats.

N. Calcutt, A. Mizisin, P. Fernyhough, 1999, Journal of the peripheral nervous system : JPNS.

The effect of mixed bovine brain gangliosides on hypoxic conduction block in control and streptozotocin-diabetic rats

N. Calcutt, A. Carrington, D. Tomlinson, 1992, Journal of the Neurological Sciences.

Diabetes and axotomy-induced deficits in retrograde axonal transport of nerve growth factor correlate with decreased levels of p75LNTR protein in lumbar dorsal root ganglia.

P. Fernyhough, D. Tomlinson, J. Delcroix, 1997, Brain research. Molecular brain research.

The involvement of noradrenergic nerves in the cardiovascular reflex responses to lower body negative pressure in the anaesthetised rabbit

P. Fentem, T. Bennett, D. Tomlinson, 1976, Pflügers Archiv.

Future prevention and treatment of diabetic neuropathy.

D. Tomlinson, 1998, Diabetes & metabolism.

Are mitogen-activated protein kinases glucose transducers for diabetic neuropathies?

D. Tomlinson, T. Purves, 2002, International review of neurobiology.

Skeletal muscle myosin heavy chain isoforms and energy metabolism after clenbuterol treatment in the rat.

P. Greenhaff, D. Tomlinson, J. Fox, 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

Effectors—Sonic Hedgehog and p38 Mitogen-Activated Protein Kinase

S. A. Price, D. Tomlinson, R. Burnand, 2007 .

Enhanced activation of axonally transported stress-activated protein kinases in peripheral nerve in diabetic neuropathy is prevented by neurotrophin-3.

P. Fernyhough, N. Sayers, D. Tomlinson, 2003, Brain : a journal of neurology.

Thioredoxin interacting protein is increased in sensory neurons in experimental diabetes

L. Zeef, I. Obrosova, N. Gardiner, 2006, Brain Research.

Prevention of Defective Axonal Transport in Streptozocin-diabetic Rats by Treatment with “Statil” (ICI 128436), an Aldose Reductase Inhibitor

D. Tomlinson, J. Townsend, Pamela Fretten, 1985, Diabetes.

Prevention of Defects of Axonal Transport in Experimental Diabetes by Aldose Reductase Inhibitors

G. Willars, D. Tomlinson, J. P. Robinson, 2012, Drugs.

Nerve conduction velocity and axonal transport of 6-phosphofructokinase activity in galactose-fed rats

N. Calcutt, G. Willars, D. Tomlinson, 1991, Journal of the Neurological Sciences.

Axonal transport of cholinergic transmitter enzymes in vagus and sciatic nerves of rats with acute experimental diabetes mellitus; correlation with motor nerve conduction velocity and effects of insulin

D. Tomlinson, J. Mayer, 1983, Neuroscience.

Reversal, by treatment with an aldose reductase inhibitor, of impaired axonal transport and motor nerve conduction velocity in experimental diabetes mellitus

D. Tomlinson, J. Mayer, Peter R. Holmes, 1982, Neuroscience Letters.

Defects of axonal transport in diabetes mellitus--a possible contribution to the aetiology of diabetic neuropathy.

D. Tomlinson, J. Mayer, D. Tomlinson, 1984, Journal of autonomic pharmacology.

Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: interactions with aldose reductase.

S. A. Price, D. Tomlinson, S. Agthong, 2004, Diabetes.

Axonal transport of noradrenaline, protein and glycoprotein in cat hypogastric nerves in vitro under conditions of high extracellular glucose

D. Tomlinson, 1983, Diabetologia.

Anterograde and retrograde axonal transport of 6-phosphofructokinase activity in the rat sciatic nerve

G. Willars, D. Tomlinson, E. F. Calthrop-Owen, 1987, Neurochemistry International.

Vasoreactivity and prostacyclin release in streptozotocin‐diabetic rats: effects of insulin or aldose reductase inhibition

F. House, G. Willars, D. Tomlinson, 1993, British journal of pharmacology.

Prevention of defects of axonal transport and nerve conduction velocity by oral administration of myo-inositol or an aldose reductase inhibitor in streptozotocin-diabetic rats

D. Tomlinson, J. Mayer, 1983, Diabetologia.

Ganglioside Treatment of Streptozotocin‐Diabetic Rats Prevents Defective Axonal Transport of 6‐Phosphofructokinase Activity

N. Calcutt, G. Willars, D. Tomlinson, 1988, Journal of neurochemistry.

Inhibition of p38 MAP Kinase Corrects Biochemical and Neurological Deficits in Experimental Diabetic Neuropathy

D. Tomlinson, S. Agthong, 2002, Annals of the New York Academy of Sciences.

Activation of JNK in Sensory Neurons Protects against Sensory Neuron Cell Death in Diabetes and on Exposure to Glucose/Oxidative Stress in Vitro

T. Purves-Tyson, P. Fernyhough, S. A. Price, 2003, Annals of the New York Academy of Sciences.

Nerve conduction impairment in experimental diabetes—proximodistal gradient of severity

D. Tomlinson, Jyoti Patel, 1999, Muscle & nerve.

Homocysteine, B vitamins, and cardiovascular disease.

D. Tomlinson, D. Lang, M. Lewis, 2006, The New England journal of medicine.

Nerve Growth Factor Modulates the Activation Status and Fast Axonal Transport of ERK 1/2 in Adult Nociceptive Neurones

G. Michael, J. Priestley, P. Fernyhough, 2001, Molecular and Cellular Neuroscience.

Transforming growth factor-beta1 and glial growth factor 2 reduce neurotrophin-3 mRNA expression in cultured Schwann cells via a cAMP-dependent pathway.

P. Fernyhough, D. Tomlinson, F. Cai, 1999, Brain research. Molecular brain research.

Reduced sciatic nerve substance P and calcitonin gene-related peptide in rats with short-term diabetes or central hypoxaemia co-exist with normal messenger RNA levels in the lumbar dorsal root ganglia

R. Leach, L. Diemel, D. Tomlinson, 1994, Neuroscience.

Opposite effects of diabetes and galactosaemia on adenosine triphosphatase activity in rat nervous tissue

G. Willars, D. Tomlinson, J. Lambourne, 1987, Diabetologia.

Autonomic neuropathy in the alloxan-diabetic rat.

D. Tomlinson, A. Yusof, 1983, Journal of autonomic pharmacology.

An examination of autonomic nervous function in genetically diabetic mice.

D. Tomlinson, S. Clarke, J. Mayer, 1982, Journal of autonomic pharmacology.

The regrowth of right atrial noradrenergic nerves after 6-hydroxydopamine in genetically diabetic mice; effects of insulin treatment.

D. Tomlinson, S. Clarke, J. Mayer, 1982, Journal of autonomic pharmacology.

Increased nerve growth factor mRNA in lateral calf skin biopsies from diabetic patients

P. Anand, P. Kopelman, P. Fernyhough, 1999, Diabetic medicine : a journal of the British Diabetic Association.

Axonal transport of substance P-like immunoreactivity in ganglioside-treated diabetic rats

N. Calcutt, G. Willars, D. Tomlinson, 1990, Journal of the Neurological Sciences.

An examination of the action of tetrabenazine on peripheral noradrenergic neurones [proceedings].

D. Tomlinson, 1977, British journal of pharmacology.

Axonal Transport of Activating Transcription Factor-2 Is Modulated by Nerve Growth Factor in Nociceptive Neurons

J. Priestley, P. Fernyhough, D. Tomlinson, 1999, The Journal of Neuroscience.

Effect of capsaicin on substance P and nerve growth factor in adjuvant arthritic rats

S. Cruwys, B. Kidd, D. Tomlinson, 1997, Neuroscience Letters.

Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy

K. Allendoerfer, T. Engber, L. Rubin, 2003 .

Engineered Zinc Finger Protein–Mediated VEGF-A Activation Restores Deficient VEGF-A in Sensory Neurons in Experimental Diabetes

S. Spratt, R. Surosky, N. Gardiner, 2009, Diabetes.

Slow Orthograde Axonal Transport of Radiolabelled Protein in Sciatic Motoneurones of Rats with Short‐Term Experimental Diabetes: Effects of Treatment with an Aldose Reductase Inhibitor or myo‐Inositol

D. Tomlinson, J. Mayer, W. Mclean, 1984, Journal of neurochemistry.

Ganglioside treatment of diabetic rats; effects on nerve adenosine triphosphatase activity and motor nerve conduction velocity.

N. Calcutt, G. Willars, D. Tomlinson, 1988, Life sciences.

Impaired orthograde axonal transport in acute hypoglycaemia, an effect mediated via hypothermia.

D. Tomlinson, P. James, 1984, Medical biology.

Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy.

K. Allendoerfer, T. Engber, L. Rubin, 2003, The Journal of clinical investigation.

Adenosine triphosphatase in nerves and ganglia of rats with streptozotocin-induced diabetes or galactosaemia; effects of aldose reductase inhibition

N. Calcutt, G. Willars, D. Tomlinson, 1988, Diabetologia.

Pulsed Field Ablation for Persistent Atrial Fibrillation (PersAFOne): Hope or Hype?

J. Mandrola, D. Tomlinson, 2020, Journal of the American College of Cardiology.

Phosphorylation of c-Jun N-terminal kinase (JNK) in sensory neurones of diabetic rats, with possible effects on nerve conduction and neuropathic pain: prevention with an aldose reductase inhibitor

D. Tomlinson, S. Agthong, A. Middlemas, 2006, Diabetologia.

Deficient Neurotrophic Support in the Aetiology of Diabetic Neuropathy

P. Fernyhough, L. Diemel, D. Tomlinson, 1996, Diabetic medicine : a journal of the British Diabetic Association.

Effects of treatment of diabetic rats with human recombinant nerve growth factor on sciatic nerve conduction, Doppler flux and substance P levels

P. Fernyhough, D. Tomlinson, K. Maeda, 1997 .

Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy

D. Tomlinson, R. Corder, L. Hounsom, 2001, Diabetologia.

Peripheral axon crush elevates transport of p75NTR in the central projection of sensory neurones of rats

J. Priestley, P. Fernyhough, D. Tomlinson, 2003, Neuroscience Letters.

Studies of sorbinil on axonal transport in streptozotocin-diabetic rats.

G. Willars, D. Tomlinson, J. Robinson, 1986, Metabolism: clinical and experimental.

Axonal transport of choline acetyltransferase and 6‐phosphofructokinase activities in genetically diabetic mice

N. Calcutt, G. Willars, D. Tomlinson, 1988, Muscle & nerve.

AXONAL TRANSPORT OF CHOLINE ACETYLTRANSFERASE AND IN GENETICALLY DIABETIC MICE 6mPHOSPHOFRUCTOKINASE ACTlVlTlES

N. Calcutt, G. Willars, D. Tomlinson, 2004 .

A role for mitogen‐activated protein kinases in the etiology of diabetic neuropathy

A. Boulton, E. Jude, P. Fernyhough, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Diminished Transcription Factor Survival Signals in Dorsal Root Ganglia in Rats with Streptozotocin‐Induced Diabetes

D. Tomlinson, T. Purves, 2002, Annals of the New York Academy of Sciences.

Nerve Growth Factor Treatment Increases Stimulus‐evoked Release of Sensory Neuropeptides in the Rat Spinal Cord

M. Malcangio, D. Tomlinson, N. Garrett, 1997, The European journal of neuroscience.

Defects of axonal transport in experimental diabetes that are unrelated to the sorbitol pathway

G. Willars, D. Tomlinson, E. F. Calthrop-Owen, 1987, Experimental Neurology.

The effects of the optical isomers of propranolol on functional refractory period in rat isolated myocardium

D. Tomlinson, S. Haworth, A. M. Ross, 1980, The Journal of pharmacy and pharmacology.