Christopher N. LaRock

发表

Pro-IL-18 secreted by keratinocytes detects the group A streptococcal protease SpeB

Doris L. LaRock, Anders F. Johnson, Jenna S. Sands, 2021, bioRxiv.

Antibiotic Treatment, Mechanisms for Failure, and Adjunctive Therapies for Infections by Group A Streptococcus

Anders F. Johnson, Christopher N. LaRock, Anders Johnson, 2021, Frontiers in Microbiology.

Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion

Ronnie H. Fang, K. Pogliano, Liangfang Zhang, 2019, Cell reports.

Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes

Doris L. LaRock, Anders F. Johnson, Jenna S. Sands, 2022, Nature.

Playing With Fire: Proinflammatory Virulence Mechanisms of Group A Streptococcus

Anders F. Johnson, Christopher N. LaRock, Shyra Wilde, 2021, Frontiers in Cellular and Infection Microbiology.

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells

V. Nizet, A. Sette, S. Crotty, 2019, Science Translational Medicine.

Burning Down the House: Cellular Actions during Pyroptosis

B. Cookson, Christopher N. LaRock, 2013, PLoS pathogens.

Combination of Lidocaine Gel and Povidone-Iodine to Decrease Acquired Infections in Procedures Performed Using Topical Anesthesia.

Y. Khalifa, Christopher N. LaRock, Riley J. Lyons, 2020, Journal of cataract and refractive surgery.

Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing.

Andrea S Theus, H. Vali, M. Mahmoudi, 2021, Molecular pharmaceutics.

Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens.

V. Nizet, Christopher N. LaRock, 2015, Biochimica et biophysica acta.

3D bioprinting of nanoparticle-laden hydrogel scaffolds with enhanced antibacterial and imaging properties

Martin L. Tomov, Andrea S Theus, V. Serpooshan, 2022, iScience.

Group A Streptococcus Infection of the Nasopharynx Requires Proinflammatory Signaling through the Interleukin-1 Receptor

Doris L. LaRock, Anders F. Johnson, Raedeen Russell, 2020, Infection and Immunity.

Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing.

V. Nizet, R. Gallo, B. Lepenies, 2015, Cell host & microbe.

Group A Streptococcal M 1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing Graphical

V. Nizet, R. Gallo, B. Lepenies, 2015 .

Inflammasome inhibition blocks cardiac glycoside cell toxicity

V. Nizet, Doris L. LaRock, P. Bushway, 2019, The Journal of Biological Chemistry.

Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones

V. Nizet, J. Pogliano, P. Nonejuie, 2017, Scientific Reports.

Role of Inflammasome-independent Activation of IL-1β by the Pseudomonas aeruginosa Protease LasB

V. Nizet, Doris L. LaRock, Joshua Olson, 2020, bioRxiv.

IL-1β is an innate immune sensor of microbial proteolysis.

V. Nizet, M. Cooper, Doris L. LaRock, 2016, Science immunology.

Opportunistic Invasive Infection by Group A Streptococcus During Anti-Interleukin-6 Immunotherapy.

V. Nizet, H. Hoffman, Christopher N. LaRock, 2020, The Journal of infectious diseases.

A Metalloprotease Secreted by the Insect Pathogen Photorhabdus luminescens Induces Melanization

David A. D'Argenio, C. Berg, D. D'Argenio, 2007, Applied and Environmental Microbiology.

Group A streptococcal M protein activates the NLRP3 inflammasome

V. Nizet, P. Ghosh, H. Hoffman, 2017, Nature Microbiology.

The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication.

V. Nizet, R. Teasdale, M. Davies, 2013, Cell host & microbe.

Inflammasome/IL-1 beta responses to streptococcal pathogens

V. Nizet, Christopher N. LaRock, 2022 .

Modeling neuro-immune interactions during Zika virus infection

V. Nizet, A. Muotri, Leon Tejwani, 2018, Human molecular genetics.

Identification and isolation of lysogens with induced prophage.

J. Livny, D. Friedman, Christopher N. LaRock, 2009, Methods in molecular biology.

3D Bioprinted Bacteriostatic Hyperelastic Bone Scaffold for Damage-Specific Bone Regeneration

Ho Won Jang, Martin L. Tomov, Andrea S Theus, 2021, Polymers.

Inflammasome/IL-1β Responses to Streptococcal Pathogens

V. Nizet, Christopher N. LaRock, 2015, Front. Immunol..

Mechanisms of inflammasome activation and inhibition during Yersinia infection

Christopher N. LaRock, 2012 .

The Pseudomonas aeruginosa protease LasB directly activates IL-1β

V. Nizet, Doris L. LaRock, Joshua Olson, 2020, EBioMedicine.

IL-1β is an innate immune sensor of microbial proteolysis

V. Nizet, M. Cooper, Doris L. LaRock, 2016, Science Immunology.

The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing.

B. Cookson, Christopher N. LaRock, 2012, Cell host & microbe.

Evidence that recurrent Group A streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant Tfh cells

V. Nizet, A. Sette, S. Crotty, 2018, bioRxiv.

A streptococcal M protein activates the NLRP 3 inflammasome

V. Nizet, P. Ghosh, H. Hoffman, 2017 .

Transcriptome Analysis of Acetyl-Homoserine Lactone-Based Quorum Sensing Regulation in Yersinia pestis

M. Parsek, A. Horswill, Christopher N. LaRock, 2013, PloS one.

Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection

Doris L. LaRock, Anders F. Johnson, Jenna S. Sands, 2023, PLoS pathogens.

Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models

D. Davies, M. Lemonnier, Doris L. LaRock, 2023, ACS infectious diseases.

Integrin-like Allosteric Properties of the Catch Bond-forming FimH Adhesin of Escherichia coli*

B. Kidd, V. Vogel, E. Sokurenko, 2008, Journal of Biological Chemistry.