I. Sabroe

J. Wild, A. Swift, D. Kiely, 2017, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Δ12-Prostaglandin J2, a Plasma Metabolite of Prostaglandin D2, Causes Eosinophil Mobilization from the Bone Marrow and Primes Eosinophils for Chemotaxis1

A. Hartnell, I. Sabroe, A. Heinemann, 2003, The Journal of Immunology.

Role of Interleukin-1 and MyD88-Dependent Signaling in Rhinovirus Infection

S. Johnston, M. Edwards, L. Parker, 2011, Journal of Virology.

The expression and roles of Toll‐like receptors in the biology of the human neutrophil

S. Dower, M. Whyte, L. Parker, 2005, Journal of leukocyte biology.

Management of acute pulmonary embolism.

D. Kiely, R. Condliffe, C. Elliot, 2015, British journal of hospital medicine.

Interleukin-1β Regulates CXCL8 Release and Influences Disease Outcome in Response to Streptococcus pneumoniae, Defining Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages

T. Mitchell, G. Pozzi, M. Nicklin, 2011, Infection and Immunity.

Inhibition of Neutrophil Apoptosis by ATP Is Mediated by the P2Y11 Receptor1

A. Surprenant, C. Bingle, M. Kassack, 2007, The Journal of Immunology.

Long‐term outcomes of domiciliary intravenous iloprost in idiopathic and connective tissue disease‐associated pulmonary arterial hypertension

D. Kiely, R. Condliffe, C. Elliot, 2017, Respirology.

Toll-Like Receptor (TLR)2 and TLR4 in Human Peripheral Blood Granulocytes: A Critical Role for Monocytes in Leukocyte Lipopolysaccharide Responses1

S. Dower, E. Jones, M. Whyte, 2002, The Journal of Immunology.

Incapacitating the immune system in cystic fibrosis

M. Whyte, I. Sabroe, 2007, Nature Medicine.

Regulation of human neutrophil chemokine receptor expression and function by activation of Toll‐like receptors 2 and 4

S. Dower, E. Jones, S. Dower, 2005, Immunology.

Basophil Responses to Chemokines Are Regulated by Both Sequential and Cooperative Receptor Signaling1

P. Askenase, K. Murakami, T. Williams, 2000, The Journal of Immunology.

Enhanced neutrophil extracellular trap formation in COVID-19 is inhibited by the protein kinase C inhibitor ruboxistaurin

E. Kiss-Toth, J. Cole, A. Condliffe, 2022, ERJ Open Research.

Enhanced neutrophil extracellular trap formation in COVID-19 is inhibited by the PKC inhibitor ruboxistaurin.

R. Hull, E. Kiss-Toth, K. Bradley, 2021, medRxiv.

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.

P. Carmeliet, P. Ratcliffe, C. Taylor, 2011, The Journal of clinical investigation.

Adults’ experiences of living with pulmonary hypertension: a thematic synthesis of qualitative studies

D. Kiely, A. Thompson, R. Condliffe, 2020, BMJ Open.

Effect of Hypoglycemia on Inflammatory Responses and the Response to Low-Dose Endotoxemia in Humans

I. Macdonald, S. Heller, R. Storey, 2018, The Journal of clinical endocrinology and metabolism.

Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes

R. Hume, J. Harwood, C. Marshall, 2016, Mucosal Immunology.

Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension

J. Wild, A. Swift, D. Capener, 2020, European Radiology.

Pulmonary arterial hypertension associated with congenital heart disease: Comparison of clinical and anatomic-pathophysiologic classification.

D. Kiely, R. Condliffe, C. Elliot, 2016, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Sarcoidosis presenting with chylothorax.

P. Jarman, I. Sabroe, M. K. Whyte, 1995, Thorax.

CT features of pulmonary arterial hypertension and its major subtypes: a systematic CT evaluation of 292 patients from the ASPIRE Registry

A. Swift, D. Kiely, S. Rajaram, 2014, Thorax.

Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.

F. Formenti, F. V. van Eeden, P. Robbins, 2014, Blood.

PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS Hypoxia-inducible factor 2 a regulates key neutrophil functions in humans , mice , and zebra fi sh

F. Formenti, P. Robbins, R. Johnson, 2014 .

Toll‐like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension

N. Arnold, L. Farkas, E. Goncharova, 2019, American journal of respiratory and critical care medicine.

The generation of highly purified primary human neutrophils and assessment of apoptosis in response to Toll-like receptor ligands.

D. Buttle, L. Parker, L. Prince, 2009, Methods in molecular biology.

Granulocyte apoptosis in the pathogenesis and resolution of lung disease.

S. Renshaw, M. Whyte, D. Dockrell, 2006, Clinical science.

Eotaxin Is Specifically Cleaved by Hookworm Metalloproteases Preventing Its Action In Vitro and In Vivo1

D. Pritchard, T. Williams, Alan P Brown, 2000, The Journal of Immunology.

Diesel exhaust particles override natural injury-limiting pathways in the lung.

K. Donaldson, R. Duffin, L. Parker, 2010, American journal of physiology. Lung cellular and molecular physiology.

CCR4 blockade does not inhibit allergic airways inflammation

T. Williams, C. Lloyd, J. Pease, 2003, Journal of leukocyte biology.

The rise and rise of Staphylococcus aureus: laughing in the face of granulocytes

S. Foster, L. Prince, I. Sabroe, 2009, Clinical and experimental immunology.

Roles of neutrophils in the regulation of the extent of human inflammation through delivery of IL‐1 and clearance of chemokines

S. Vogel, S. Walmsley, L. Bingle, 2013, Journal of leukocyte biology.

Chemokines: An Overview

T. Williams, I. Sabroe, T. Williams, 2001 .

Chemokines, innate and adaptive immunity, and respiratory disease

S. Dower, S. Dower, J. Pease, 2002, European Respiratory Journal.

Roles of chemokines in the regulation of leucocyte recruitment.

T. Williams, J. Pease, I. Sabroe, 2001, Clinical science.

Vitro and In Vivo Metalloproteases Preventing Its Action In Eotaxin Is Specifically Cleaved by Hookworm

D. Pritchard, T. Williams, Alan P Brown, 2000 .

Monoclonal Antibody In Vivo Chemokine Receptor-3: Blockade Using a Pig Eosinophil Eotaxin Receptor, C-C Cloning and Characterization of the Guinea

T. Williams, P. Jose, C. Gerard, 1998 .

Cloning and characterization of the guinea pig eosinophil eotaxin receptor, C-C chemokine receptor-3: blockade using a monoclonal antibody in vivo.

I. Sabroe, P. Ponath, Y. Li, 1998, Journal of immunology.

ASPIRE registry: Assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre

J. Wild, D. Capener, D. Kiely, 2011, European Respiratory Journal.

Variations in Eosinophil Chemokine Responses: An Investigation of CCR1 and CCR3 Function, Expression in Atopy, and Identification of a Functional CCR1 Promoter1

T. Williams, J. Pease, I. Sabroe, 2003, The Journal of Immunology.

A central role for monocytes in Toll‐like receptor‐mediated activation of the vasculature

Graham M Lord, D. Crossman, S. Francis, 2009, Immunology.

Eotaxin (CCL11) and Eotaxin-2 (CCL24) Induce Recruitment of Eosinophils, Basophils, Neutrophils, and Macrophages As Well As Features of Early- and Late-Phase Allergic Reactions Following Cutaneous Injection in Human Atopic and Nonatopic Volunteers1

A. Kay, T. Williams, A. Menzies-Gow, 2002, The Journal of Immunology.

Macrophage Phenotype Is Associated with Disease Severity in Preterm Infants with Chronic Lung Disease

S. Kotecha, E. McGreal, M. Whyte, 2014, PloS one.

Human Rhinovirus Inhibits Macrophage Phagocytosis of Bacteria in Chronic Obstructive Pulmonary Disease. More Than a Common Cold

A. Ho, D. Dockrell, I. Sabroe, 2019, American journal of respiratory and critical care medicine.

Central venous catheter-related blood stream infections in patients receiving intravenous iloprost for pulmonary hypertension

D. Kiely, R. Condliffe, R. Condliffe, 2013, European Journal of Clinical Microbiology & Infectious Diseases.

CXCR1+CD4+ T Cells in Human Allergic Disease1

S. Durham, M. Jacobson, S. Till, 2004, The Journal of Immunology.

Critical care outcomes in patients with pre-existing pulmonary hypertension: insights from the ASPIRE registry

G. Mills, D. Kiely, R. Condliffe, 2021, ERJ Open Research.

MyD 88-dependent signaling in rhinoviral infection 1 2

S. Johnston, M. Edwards, L. Parker, 2011 .

The role of TLRs in neutrophil activation.

M. Whyte, L. Parker, L. Prince, 2011, Current opinion in pharmacology.

Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis

R. Storey, Mark R Thomas, V. Ridger, 2015, Vascular pharmacology.

The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension

J. Wild, A. Swift, D. Kiely, 2018, European Respiratory Journal.

Xenon ventilation MRI in difficult asthma: initial experience in a clinical setting

A. Biancardi, H. Marshall, J. Wild, 2021, ERJ Open Research.

Lung MRI with hyperpolarised gases: current & future clinical perspectives

A. Biancardi, H. Marshall, J. Wild, 2021, The British journal of radiology.

Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK)

I. Pavord, A. Woodcock, Dirk E. Smith, 2015, Thorax.

DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator

M. Rothenberg, R. Schicho, G. Marsche, 2018, Journal of leukocyte biology.

Airway Epithelial Cells Generate Pro-inflammatory Tenascin-C and Small Extracellular Vesicles in Response to TLR3 Stimuli and Rhinovirus Infection

M. Edwards, K. Midwood, L. Parker, 2019, Front. Immunol..

T lymphocytes expressing CCR3 are increased in allergic rhinitis compared with non‐allergic controls and following allergen immunotherapy

S. Durham, S. Till, C. Lloyd, 2007, Allergy.

Role of Interleukin-1 and MyD88-Dependent Signaling in Rhinovirus Infection (cid:1)

S. Johnston, M. Edwards, L. Parker, 2011 .

Toll-Like Receptor (TLR)2 and TLR4 in Human Peripheral Blood Granulocytes: A Critical Role for Monocytes in Leukocyte Lipopolysaccharide Responses

S. Dower, I. Sabroe, Lynne R. Usher, 2002 .

Critical Role for Monocytes in Leukocyte Human Peripheral Blood Granulocytes : A Toll-Like Receptor ( TLR ) 2 and TLR 4 in Whyte and

S. Dower, E. Jones, I. Sabroe, 2002 .

9α,11β‐PGF2 and its stereoisomer PGF2α are novel agonists of the chemoattractant receptor, CRTH2

Ashley A. Barnes, J. Pease, I. Sabroe, 2006 .

The yin and the yang of immunosuppression with inhaled corticosteroids

D. Postma, I. Heijink, D. Dockrell, 2013, Thorax.

Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation

C. Bingle, S. Renshaw, M. Whyte, 2011, PloS one.

Pathophysiology and Diagnosis of Pulmonary Hypertension Due to Left Heart Disease

Robert A. Lewis, D. Kiely, R. Condliffe, 2018, Front. Med..

Diagnosis of Pulmonary Hypertension with Cardiac MRI: Derivation and Validation of Regression Models

J. Wild, A. Swift, D. Kiely, 2018, Radiology.

CCR4 in human allergen‐induced late responses in the skin and lung

S. Durham, E. Varga, M. Jacobson, 2002, European journal of immunology.

Pellino-1 Selectively Regulates Epithelial Cell Responses to Rhinovirus

I. Heijink, M. van den Berge, M. Whyte, 2012, Journal of Virology.

Pellino-1 Regulates the Responses of the Airway to Viral Infection

J. Stewart, Shao-Cong Sun, W. Timens, 2018, Frontiers in Cellular and Infection Microbiology.

UK consensus statement on the diagnosis of inducible laryngeal obstruction in light of the COVID‐19 pandemic

S. Fowler, J. Hull, J. Haines, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Editorial: RSV: a new box of delights for an old enemy

F. Culley, D. Dockrell, I. Sabroe, 2014, Journal of leukocyte biology.

Promoter Identification of a Functional CCR 1 CCR 3 Function , Expression in Atopy , and Responses : An Investigation of CCR 1 and Variations in Eosinophil Chemokine

T. Williams, J. Pease, I. Sabroe, 2003 .

The carboxyl terminus of the chemokine receptor CCR3 contains distinct domains which regulate chemotactic signaling and receptor down‐regulation in a ligand‐dependent manner

T. Williams, P. Murphy, J. Pease, 2005, European journal of immunology.

Characterisation of the biological activity of recombinant equine eotaxin in vitro.

M. Collins, A. Hamblin, I. Sabroe, 2002, Cytokine.

The CC Chemokine Eotaxin (CCL11) Is a Partial Agonist of CC Chemokine Receptor 2b*

T. Williams, G. Larosa, J. Pease, 2001, The Journal of Biological Chemistry.

T Cell Phenotypes of the Normal Nasal Mucosa: Induction of Th2 Cytokines and CCR3 Expression by IL-41

S. Durham, S. Till, T. Williams, 2001, The Journal of Immunology.

Idiopathic and Systemic Sclerosis‐Associated Pulmonary Arterial Hypertension: A Comparison of Demographic, Hemodynamic, and MRI Characteristics and Outcomes

A. Swift, D. Kiely, R. Condliffe, 2017, Chest.

Deﬁciency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and ﬁbrosis

R. Chambers, N. Arnold, S. Walmsley, 2022 .

Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa.

G. Taylor, P. Henson, H. Marriott, 2008, American journal of respiratory and critical care medicine.

Temporal Interleukin-1β Secretion from Primary Human Peripheral Blood Monocytes by P2X7-independent and P2X7-dependent Mechanisms*

D. Crossman, S. Francis, J. Ward, 2010, The Journal of Biological Chemistry.

DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus through Interleukin-1β Signaling

L. Parker, I. Sabroe, C. A. Stokes, 2018, Journal of Virology.

Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor

S. Dower, R. Storey, L. Bingle, 2005, Thrombosis and Haemostasis.

Causes Eosinophil Mobilization from the Bone Marrow and Primes Eosinophils for Chemotaxis

A. Hartnell, I. Sabroe, A. Heinemann, 2003 .

EmPHasis-10 health-related quality of life score predicts outcomes in patients with idiopathic and connective tissue disease-associated pulmonary arterial hypertension: results from a UK multicentre study

K. Dimopoulos, A. Peacock, J. Yorke, 2020, European Respiratory Journal.

Elevated CCR6+ CD4+ T lymphocytes in tissue compared with blood and induction of CCL20 during the asthmatic late response

S. Till, I. Sabroe, S. Durham, 2008, Clinical and experimental immunology.

Identifying and addressing health inequalities in asthma care

I. Sabroe, Dermot Ryan, D. Ryan, 2021, European Respiratory Journal.

Agonists of toll-like receptors 2 and 4 activate airway smooth muscle via mononuclear leukocytes.

S. Dower, G. E. Morris, P. Jose, 2005, American journal of respiratory and critical care medicine.

Interleukin-1 (cid:1) Regulates CXCL8 Release and Inﬂuences Disease Outcome in Response to Streptococcus pneumoniae , Deﬁning Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages

T. Mitchell, G. Pozzi, M. Nicklin, 2022 .

What can we learn from highly purified neutrophils?

S. Dower, S. Walmsley, L. Prince, 2004, Biochemical Society transactions.

Examining the impact of pulmonary hypertension on nonprofessional caregivers: A mixed‐methods systematic review

D. Kiely, A. Thompson, R. Condliffe, 2022, Pulmonary circulation.

Elective lower limb orthopedic arthroplasty surgery in patients with pulmonary hypertension

Robert A. Lewis, D. Kiely, R. Condliffe, 2021, Pulmonary circulation.

TOLL-LIKE RECEPTORS

S. Dower, M. Whyte, I. Sabroe, 2006 .

Phosphoinositide-3 Kinase Inhibition Modulates Responses to Rhinovirus by Mechanisms that Are Predominantly Independent of Autophagy

J. Juss, L. Parker, I. Sabroe, 2014, PloS one.

Pathways regulating lipopolysaccharide‐induced neutrophil survival revealed by lentiviral transduction of primary human neutrophils

S. Renshaw, M. Whyte, L. Prince, 2009, Immunology.

Ambrisentan therapy in pulmonary hypertension: clinical use and tolerability in a referral centre

D. Kiely, R. Condliffe, C. Elliot, 2014, Therapeutic advances in respiratory disease.

The care of dying people in 16th- and 17th-century England

I. Sabroe, L. Germain, 2020, Death studies.

Human Atopic and Nonatopic Volunteers Reactions Following Cutaneous Injection in Features of Early-and Late-Phase Allergic Neutrophils , and Macrophages As Well As Basophils , Induce Recruitment of Eosinophils , Eotaxin ( CCL 11 ) and Eotaxin-2 ( CCL 24 )

A. Kay, T. Williams, A. Menzies-Gow, 2002 .

Subversion of a Lysosomal Pathway Regulating Neutrophil Apoptosis by a Major Bacterial Toxin, Pyocyanin1

G. Taylor, S. Walmsley, D. Buttle, 2008, The Journal of Immunology.

Bacterial Toxin , Pyocyanin Regulating Neutrophil Apoptosis by a Major Subversion of a Lysosomal Pathway Dockrell and

G. Taylor, S. Walmsley, D. Buttle, 2008 .

Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways.

S. Bel, J. Pease, A. Hartnell, 1999, Journal of immunology.

Staphylococcus aureus Induces Eosinophil Cell Death Mediated by α-hemolysin

S. Foster, M. Whyte, L. Prince, 2012, PloS one.

Edinburgh Research Explorer Staphylococcus aureus Induces Eosinophil Cell Death Mediated by alpha-hemolysin

S. Foster, M. Whyte, L. Prince, 2012 .

Chemoattractant cross-desensitization of the human neutrophil IL-8 receptor involves receptor internalization and differential receptor subtype regulation.

T. Williams, C. Hébert, I. Sabroe, 1997, Journal of immunology.

An audit of the use of self‐administered adrenaline syringes in patients with angio‐oedema

R. Sabroe, I. Sabroe, F. Lawlor, 2002, The British journal of dermatology.

Potentiation of TLR4 signalling by plasmin activity.

S. Dower, J. Ward, D. Buttle, 2006, Biochemical and biophysical research communications.

NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival.

P. Taylor, F. Falciani, S. Renshaw, 2017, Blood.

9alpha,11beta-PGF2 and its stereoisomer PGF2alpha are novel agonists of the chemoattractant receptor, CRTH2.

Ashley A. Barnes, J. Pease, I. Sabroe, 2006, FEBS letters.

The role of IL-1 and MyD88-dependent signaling in rhinoviral infection 1 ऀð 2 ऀð

S. Johnston, M. Edwards, L. Parker, 2011 .

Toll-like receptor (TLR) 4 polymorphisms and COPD.

R. Hubbard, S. Dower, I. Sabroe, 2004, Thorax.

Mediated by the P 2 Y Inhibition of Neutrophil Apoptosis by ATP Is

A. Surprenant, M. Kassack, L. Stokes, 2007 .

Partial anomalous pulmonary venous drainage in patients presenting with suspected pulmonary hypertension: A series of 90 patients from the ASPIRE registry

Robert A. Lewis, K. English, A. Swift, 2020, Respirology.

Characteristics And Outcomes In Pulmonary Hypertension Associated With COPD/ Emphysema: Results From The ASPIRE Registry

J. Wild, A. Swift, D. Kiely, 2012, ATS 2012.

Treatment of adenoviral pneumonitis with intravenous ribavirin and immunoglobulin.

W. Lynn, S. Shaunak, D. Tait, 1995, Thorax.

A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models

S. Renshaw, I. Sabroe, Noémie Hamilton, 2018, F1000Research.

Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood

M. Dunning, M. Humbert, P. Corris, 2021, Nature Communications.

Pulmonary hypertension: diagnosis and management

D. Kiely, R. Condliffe, C. Elliot, 2013, BMJ : British Medical Journal.

Contrary prostaglandins: the opposing roles of PGD2 and its metabolites in leukocyte function

J. Pease, I. Sabroe, H. Sandig, 2007, Journal of leukocyte biology.

Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists.

P. Barnes, R. Wilhelm, T. Williams, 2002, American journal of respiratory and critical care medicine.

Translational Mini‐Review Series on Toll‐like Receptors: Networks regulated by Toll‐like receptors mediate innate and adaptive immunity

L. Parker, L. Prince, I. Sabroe, 2007, Clinical and experimental immunology.

S132 Investigating the role of Pellino1, an E3 ubiquitin ligase, in modulating signalling pathways controlling the inflammatory response

M. Whyte, L. Parker, L. Prince, 2011, Thorax.

A Bittersweet Response to Infection in Diabetes; Targeting Neutrophils to Modify Inflammation and Improve Host Immunity

S. Heller, L. Prince, I. Sabroe, 2021, Frontiers in Immunology.

The Identification, Characterization, and Distribution of Guinea Pig CCR4 and Epitope Mapping of a Blocking Antibody*

T. Williams, T. Mitchell, J. Pease, 2002, The Journal of Biological Chemistry.

The Role of Interleukin-8 and its Receptors in Inflammatory Lung Disease

J. Pease, I. Sabroe, 2002, American journal of respiratory medicine : drugs, devices, and other interventions.

The Utilization of Cultural Movements to Overcome Stigma in Narrative of Postnatal Depression

C. Millard, I. Sabroe, Grace Elliott, 2020, Frontiers in Psychiatry.

The role of TLR activation in inflammation

S. Dower, S. Dower, L. Parker, 2008, The Journal of pathology.

Endotoxin tolerance induces selective alterations in neutrophil function

S. Dower, M. Whyte, L. Parker, 2005, Journal of leukocyte biology.

Toll-like receptors and chronic lung disease.

S. Dower, M. Whyte, I. Sabroe, 2005, Clinical science.

Rhinoviral infection and asthma: the detection and management of rhinoviruses by airway epithelial cells

L. Parker, I. Sabroe, C. A. Stokes, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Pulmonary hypertension in COPD: results from the ASPIRE registry

J. Wild, A. Swift, D. Kiely, 2012, European Respiratory Journal.

Reducing the toll of inflammatory lung disease.

M. Whyte, I. Sabroe, N. Chaudhuri, 2007, Chest.

Basic science of the innate immune system and the lung.

I. Sabroe, N. Chaudhuri, 2008, Paediatric respiratory reviews.

Toll-Like Receptors in Health and Disease: Complex Questions Remain1

S. Dower, S. Vogel, R. Read, 2003, The Journal of Immunology.

Toll-Like Receptors in Health and Disease : Complex Questions Remain 1

S. Dower, S. Vogel, R. Read, 2003 .

Cooperative molecular and cellular networks regulate Toll‐like receptor‐dependent inflammatory responses

Christopher E Brightling, Peter Bradding, Gavin E Morris, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Toll‐like receptors: their role in allergy and non‐allergic inflammatory disease

S. Dower, L. Parker, I. Sabroe, 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

"Dirty little secrets"--endotoxin contamination of recombinant proteins.

S. Howie, C. Gregory, S. Wakelin, 2006, Immunology letters.

S. Francis, S. Renshaw, A. Lawrie, 2011, Journal of leukocyte biology.

Toll-Like Receptor (TLR)2 and TLR4 Agonists Regulate CCR Expression in Human Monocytic Cells1

S. Dower, S. Vogel, M. Whyte, 2004, The Journal of Immunology.

Monocytic Cells HumanAgonists Regulate CCR Expression in Toll-Like Receptor ( TLR ) 2 and TLR 4

S. Dower, S. Vogel, M. Whyte, 2004 .

Characterization of the survival effect of tumour necrosis factor-alpha in human neutrophils.

A. Cowburn, S. Walmsley, N. Farahi, 2004, Biochemical Society transactions.

Platelet P2Y12 Inhibitors Reduce Systemic Inflammation and Its Prothrombotic Effects in an Experimental Human Model

R. Storey, R. Ajjan, Mark R Thomas, 2015, Arteriosclerosis, thrombosis, and vascular biology.

A Bayesian approach to copy-number-polymorphism analysis in nuclear pedigrees.

M. Teare, Jonathan Goke, J. Göke, 2007, American journal of human genetics.

Indomethacin Causes Prostaglandin D2-like and Eotaxin-like Selective Responses in Eosinophils and Basophils*

T. Williams, A. Hartnell, I. Sabroe, 2002, The Journal of Biological Chemistry.

Combining creative writing and narrative analysis to deliver new insights into the impact of pulmonary hypertension

D. Kiely, R. Condliffe, C. Elliot, 2017, BMJ Open Respiratory Research.

Maximal Exercise Testing Using the Incremental Shuttle Walking Test Can Be Used to Risk-Stratify Patients with Pulmonary Arterial Hypertension

J. Wild, A. Swift, D. Kiely, 2020, Annals of the American Thoracic Society.

Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension

Robert A. Lewis, A. Swift, D. Kiely, 2020, European Respiratory Journal.

Identification of Cardiac Magnetic Resonance Imaging Thresholds for Risk Stratification in Pulmonary Arterial Hypertension

Robert A. Lewis, J. Wild, A. Swift, 2020, American journal of respiratory and critical care medicine.

Diesel Exhaust Particle Exposure In Vitro Alters Monocyte Differentiation and Function

Dave Singh, K. Donaldson, R. Duffin, 2012, PloS one.

A social‐technological epistemology of clinical decision‐making as mediated by imaging

A. Carusi, Sophie van Baalen, D. Kiely, 2016, Journal of evaluation in clinical practice.

Central venous catheter-related blood stream infections in patients receiving intravenous iloprost for pulmonary hypertension

D. Kiely, R. Condliffe, J. Hurdman, 2013, European Journal of Clinical Microbiology & Infectious Diseases.

Medical artificial intelligence is as much social as it is technological

F. Ciravegna, A. Carusi, D. Kiely, 2023, Nature Machine Intelligence.

A Proteomics-Based Assessment of Inflammation Signatures in Endotoxemia

M. Mayr, M. Shankar-Hari, U. Mayr, 2020, Molecular & cellular proteomics : MCP.

Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y12 Inhibition

M. Mayr, M. Shankar-Hari, A. Braza-Boïls, 2020, International journal of molecular sciences.

A matter of time: study of circadian clocks and their role in inflammation

A. Loudon, D. Ray, H. Durrington, 2016, Journal of leukocyte biology.

Toll-like receptor (TLR)-based networks regulate neutrophilic inflammation in respiratory disease.

I. Sabroe, M. Whyte, 2007, Biochemical Society transactions.

Practical phenotyping of dif fi cult asthma

L. Heaney, R. Green, R. Niven, 2014 .

Practical phenotyping of difficult asthma

L. Heaney, R. Green, R. Niven, 2013, Thorax.

Practical and conceptual models of chronic obstructive pulmonary disease.

S. Dower, M. Whyte, L. Parker, 2007, Proceedings of the American Thoracic Society.

Pathological networking: a new approach to understanding COPD

P. Calverley, S. Dower, M. Whyte, 2007, Thorax.

Pathological networking: a new approach to understanding COPD.

P. Calverley, S. Dower, M. Whyte, 2007, Thorax.

Differential and cell‐type specific regulation of responses to Toll‐like receptor agonists by ISO‐1

Lisa C Parker, Ian Sabroe, L. Parker, 2008, Immunology.

Error, injustice, and physician wellbeing

M. Fricker, C. Millard, I. Sabroe, 2021, The Lancet.

Physician narratives of illness

C. Millard, I. Sabroe, Amy Wilson, 2019, The Lancet.

Monocyte and macrophage dysfunction as a cause of HIV-1 induced dysfunction of innate immunity.

R. Miller, M. Noursadeghi, D. Dockrell, 2010, Current molecular medicine.

Bosutinib therapy resulting in severe deterioration of pre-existing pulmonary arterial hypertension

D. Kiely, R. Condliffe, C. Elliot, 2016, European Respiratory Journal.

A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models

S. Renshaw, I. Sabroe, Noémie Hamilton, 2018, F1000Research.

Non-CCR3 Pathways Chemokine Signaling Via CCR3 and Differential Regulation of Eosinophil

T. Williams, J. Pease, A. Hartnell, 1999 .

Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease

Shao-Cong Sun, A. Condliffe, H. Marriott, 2019, Front. Immunol..

Measurement of granulocyte pharmacodynamics in whole blood by flow cytometry.

P. Barnes, T. Hansel, I. Sabroe, 2001, Methods in molecular medicine.

Low Dose

S. Heller, R. Storey, R. McCrimmon, 2019 .

Effect of hypoglycemia on inflammatory responses and the response to low dose endotoxemia in humans

S. Heller, R. Storey, S. Francis, 2018 .

Platelet P2Y12 Inhibitors Reduce Systemic Inflammation and Its Prothrombotic Effects in an Experimental Human Model

R. Storey, R. Ajjan, Mark R Thomas, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Macrophage Phenotype Is Associated with Disease Severity in Preterm Infants with Chronic Lung Disease

S. Kotecha, E. McGreal, M. Whyte, 2014, PloS one.

Editorial: RSV: a new box of delights for an old enemy

F. Culley, D. Dockrell, I. Sabroe, 2014, Journal of leukocyte biology.

Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation

C. Bingle, S. Renshaw, M. Whyte, 2011, PloS one.

Thromboembolic occlusion of a pulmonary arteriovenous malformation. A very unusual pulmonary embolism.

I. Sabroe, 1995, BMJ.