L. Reznikov

发表

Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein

D. Yoon, C. Dinarello, Soohyun Kim, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Identification of Amino Acid Residues Critical for Biological Activity in Human Interleukin-18*

D. Yoon, C. Dinarello, Soohyun Kim, 2002, The Journal of Biological Chemistry.

Specific Inhibition of Histone Deacetylase 8 Reduces Gene Expression and Production of Proinflammatory Cytokines in Vitro and in Vivo*

A. Abbate, C. Dinarello, G. Fossati, 2014, The Journal of Biological Chemistry.

A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity

C. Dinarello, Sanjay Kumar, Soohyun Kim, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1β

A. Harken, C. Dinarello, L. Reznikov, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect.

C. Dinarello, J. Ferrara, Y. Maeda, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Cisplatin-Induced Acute Renal Failure Is Associated with an Increase in the Cytokines Interleukin (IL)-1β, IL-18, IL-6, and Neutrophil Infiltration in the Kidney

C. Edelstein, S. Faubel, C. Dinarello, 2007, Journal of Pharmacology and Experimental Therapeutics.

Suppression of tumor necrosis factor alpha production by cAMP in human monocytes: dissociation with mRNA level and independent of interleukin-10.

R. McIntyre, A. Harken, B. Shames, 2001, The Journal of surgical research.

Melanoma inhibits macrophage activation by suppressing toll-like receptor 4 signaling.

M. McCarter, A. Harken, M. Walsh, 2005, Journal of the American College of Surgeons.

Liposomal Delivery of Purified Inhibitory-κBα Inhibits Tumor Necrosis Factor-α–Induced Human Vascular Smooth Muscle Proliferation

A. Harken, C. Dinarello, Xianzhong Meng, 1999 .

Pharmacokinetics , Safety and Inducible Cytokine Responses during a Phase 1 Trial of the Oral Histone Deacetylase Inhibitor ITF 2357 ( Givinostat )

C. Dinarello, A. Furlan, G. Fossati, 2011 .

The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines

G. Fantuzzi, C. Dinarello, Soohyun Kim, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Differences in signaling pathways by IL-1beta and IL-18.

C. Dinarello, Soohyun Kim, E. Lewis, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Suppression of endotoxin-inducible cytokines in whole blood from human subjects following single dose of recombinant human interleukin-11

G. Fantuzzi, A. Puren, C. Dinarello, 1999 .

IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma.

G. Fantuzzi, J. Westcott, S. Kim, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Ischemia Alone is Sufficient to Induce TNF-&agr; mRNA and Peptide in the Myocardium

C. Cairns, A. Harken, Xianzhong Meng, 2002, Shock.

The Combination of Soluble IL-18Rα and IL-18Rβ Chains Inhibits IL-18-Induced IFN-γ

M. Tsang, C. Dinarello, Soohyun Kim, 2002 .

Functional Reconstitution and Regulation of IL-18 Activity by the IL-18Rβ Chain1

H. Young, C. Dinarello, C. Selzman, 2001, The Journal of Immunology.

Pentoxifylline protects against endotoxin-induced acute renal failure in mice.

R. Schrier, S. Falk, Wei Wang, 2006, American journal of physiology. Renal physiology.

Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis.

C. Edelstein, S. Faubel, C. Dinarello, 2004, Kidney international.

Interleukin-10 attenuates the response to vascular injury.

C. Selzman, M. Zimmerman, L. Reznikov, 2004, The Journal of surgical research.

Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF.

M. Netea, G. Fantuzzi, C. Dinarello, 2003, Cytokine.

Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice.

Y. Tao, Jun Kim, R. Schrier, 2005, American journal of physiology. Renal physiology.

Atherogenic effects of Chlamydia pneumoniae: refuting the innocent bystander hypothesis.

M. Netea, F. Grover, C. Dinarello, 2003, The Journal of thoracic and cardiovascular surgery.

Hemorrhage-induced acute lung injury is TLR-4 dependent.

R. McIntyre, A. Harken, E. Abraham, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8.

G. Fantuzzi, A. Puren, D. Yoon, 1998, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.

G. Fantuzzi, C. Dinarello, Soohyun Kim, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Overview of interleukin‐18: more than an interferon‐γ inducing factor

G. Fantuzzi, A. Puren, D. Yoon, 1998, Journal of leukocyte biology.

Eukaryotic translation initiation factor 5A small interference RNA-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury.

C. Dinarello, W. Scheld, C. Moore, 2008, The Journal of infectious diseases.

Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18.

M Eisenstein, M. Eisenstein, G. Fantuzzi, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.

G. Fantuzzi, S. Kim, L. Reznikov, 1999, Immunity.

Utilization of endoscopic inoculation in a mouse model of intrauterine infection-induced preterm birth: role of interleukin 1beta.

G. Fantuzzi, C. Dinarello, B. Shames, 1999, Biology of reproduction.

The Histone Deacetylase Inhibitor ITF2357 Reduces Production of Pro-Inflammatory Cytokines In Vitro and Systemic Inflammation In Vivo

G. Fantuzzi, C. Dinarello, P. Pagani, 2005, Molecular medicine.

Interleukin-1β deficiency results in reduced NF-κB levels in pregnant mice

G. Fantuzzi, C. Dinarello, Soohyun Kim, 2000 .

Interleukin-1 b deﬁciency results in reduced NF- k B levels in pregnant mice

G. Fantuzzi, C. Dinarello, Soohyun Kim, 1999 .

TNF receptor I is required for induction of macrophage heat shock protein 70.

A. Harken, J. Heimbach, C. Dinarello, 2001, American journal of physiology. Cell physiology.

Pharmacokinetics, Safety and Inducible Cytokine Responses during a Phase 1 Trial of the Oral Histone Deacetylase Inhibitor ITF2357 (Givinostat)

C. Dinarello, A. Furlan, G. Fossati, 2011, Molecular medicine.

Relative contribution of the TNF-α receptors to murine intimal hyperplasia

C. Selzman, M. Zimmerman, L. Reznikov, 2003 .

Lack of TNF-α attenuates intimal hyperplasia after mouse carotid artery injury

A. Harken, Xianzhong Meng, C. Selzman, 2002 .

Interleukin-11 attenuates human vascular smooth muscle cell proliferation.

R. McIntyre, A. Harken, C. Selzman, 2002, American journal of physiology. Heart and circulatory physiology.

Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain.

H. Young, C. Dinarello, C. Selzman, 2001, Journal of immunology.

Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells.

C. Dinarello, T. Niwa, M. Pischetsrieder, 2004, Clinical nephrology.

Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation.

A. Harken, C. Dinarello, B. Shames, 1999, Circulation Research.

Specific Inhibition of Histone Deacetylase 8 Reduces Gene Expression and Production of Proinflammatory Cytokines in Vitro and in Vivo*

A. Abbate, C. Dinarello, G. Fossati, 2014, The Journal of Biological Chemistry.

Lack of TNF-alpha attenuates intimal hyperplasia after mouse carotid artery injury.

A. Harken, Xianzhong Meng, C. Selzman, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.