P. Helissey

发表

A new model of pre-B acute lymphoblastic leukemia chemically induced in rats.

M. Arock, C. Jacquemont, N. Bernard, 2005, Experimental hematology.

Design, Synthesis, and Biological Evaluation of the First Podophyllotoxin Analogues as Potential Vascular‐Disrupting Agents

M. Vidal, C. Lenoir, C. Garbay, 2010, ChemMedChem.

KHSO4-Assisted Michael Addition–Elimination Reactions of Indole with 3-Dimethylamino-1-phenylprop-2-en-1-ones in Water: An Environmentally Friendly Synthesis of Novel 3-Indolylchalcones

P. Helissey, R. Nongkhlaw, A. Devi, 2013 .

Porphyrin-netropsin: A potential ligand of DNA

N. Gresh, M. Perrée-fauvet, P. Helissey, 1993 .

Binding of Net-Fla, a netropsin-flavin hybrid molecule, to DNA: molecular mechanics and dynamics studies in vacuo and in water solution.

M. Bouziane, M. Le Bret, C. Auclair, 1996, Journal of biomolecular structure & dynamics.

A FACILE ROUTE FOR THE PREPARATION OF N-PHENYL TETRAHYDROQUINOLINES AND TETRAHYDROISOQUINOLINES

C. Tratrat, P. Helissey, S. Giorgi-Renault, 2001 .

Polycyclic nitrogen heterocycles as potential thymidine phosphorylase inhibitors: synthesis, biological evaluation, and molecular docking study

M. Sari, P. Chavatte, A. Farce, 2021, Journal of enzyme inhibition and medicinal chemistry.

Efficient synthesis of diversely substituted pyrazolo[1,5-a]pyrimidine derivatives promoted by ultrasound irradiation in water and their antibacterial activities

P. Helissey, Abhik Sen, J. N. Vishwakarma, 2020 .

Poly(pyrrolecarboxamides) linked to photoactivable chromophore isoalloxazine. Synthesis, selective binding, and DNA cleaving properties.

C. Auclair, P. Helissey, S. Giorgi-Renault, 1994, Bioconjugate chemistry.

Inhibition of eukaryotic DNA topoisomerase I and II activities by indoloquinolinedione derivatives.

J. Riou, P. Helissey, S. Giorgi-Renault, 1991, Molecular pharmacology.

A facile, regioselective synthesis of novel 3-(N-phenylcarboxamide)pyrazolo[1,5-a]pyrimidine analogs in the presence of KHSO$$_{4}$$4 in aqueous media assisted by ultrasound and their antibacterial activities

L. I. Singha, P. Helissey, J. N. Vishwakarma, 2016, Molecular Diversity.

NEW SYNTHESIS OF 5,10-DIOXYPHENAZINE-2-CARBOXYLIC ACID

P. Helissey, S. Giorgi-Renault, M. Haroun, 2001 .

A new synthetic approach to functionalize pyrimido[4,5-b]quinoline-2,4(1H,3H)-diones via a three-component one-pot reaction

P. Helissey, Stéphanie Desbène-Finck, S. Giorgi-Renault, 2010, Molecular Diversity.

Design and effective synthesis of the first 4-aza-2,3-didehydropodophyllotoxin rigid aminologue: a N-methyl-4-[(3,4,5-trimethoxyphenyl)amino)]-1,2-dihydroquinoline-lactone.

P. Helissey, Raphaël Labruère, Stéphanie Desbène-Finck, 2008, The Journal of organic chemistry.

Efficient synthesis, structure elucidation, and anti-parasitic activities of novel quinolinyl β–enaminones

Shikha Mishra, P. Helissey, M. Srivastava, 2021, Monatshefte für Chemie - Chemical Monthly.

Silver-Catalyzed Domino Hydroarylation/Cycloisomerization Reactions of 2-Alkynylquinoline-3-carbaldehydes: Access to (Hetero)arylpyranoquinolines

V. Michelet, P. Helissey, Stéphanie Desbène-Finck, 2016 .

Synthesis, antitumor evaluation and SAR of new 1H-pyrrolo [3,2-c] quinoline-6,9-diones and 11H-indolo [3,2-c] quinoline-1,4-diones.

P. Helissey, S. Giorgi-Renault, S. Cros, 1994, Anti-cancer drug design.

A FACILE ULTRASOUND-ASSISTED REGIOSELECTIVE SYNTHETIC STRATEGY FOR PYRAZOLO(1,5-a)PYRIMIDINES MEDIATED BY KHSO4 IN AQUEOUS MEDIA

P. Helissey, U. Kalita, S. Kaping, 2014 .

Synthesis of Novel Bis-enaminones by KHSO4-assisted Facile Michael Addition-elimination Reaction of 3-(dimethylamino)-1-phenylprop-2-en-1-ones with Diamines in Water

P. Helissey, A. Devi, J. N. Vishwakarma, 2011 .

Heterocyclic quinones. XIV. Pharmacomodulation in a series of 11H-indolo[3,2-c]quinolinediones: synthesis and cytotoxicity of 8-substituted 11H-indolo[3,2-c]quinoline-7,10-diones.

P. Helissey, S. Giorgi-Renault, S. Cros, 1989, Chemical & pharmaceutical bulletin.

Structure-mutagenicity relationships in a series of indolo[3,2-c]quinoline-1,4-diones that have shown cytotoxic properties on leukemia cells.

B. Festy, P. Helissey, S. Giorgi-Renault, 1992, Mutation research.

New Synthesis of 5,10‐Dioxyphenazine‐2‐carboxylic Acid.

P. Helissey, S. Giorgi-Renault, M. Haroun, 2001 .

Sequence-recognition and cleavage of DNA by a netropsin-phenazine-di-N-oxide conjugate.

C. Bailly, P. Colson, C. Houssier, 2000, Bioconjugate chemistry.

Synthesis of New Furo[3,4‐b]quinolin‐1(3H)‐one Scaffolds Derived from γ‐Lactone‐Fused Quinolin‐4(1H)‐ones

P. Helissey, Raphaël Labruère, Stéphanie Desbène-Finck, 2013 .

Easy Access to 1H-Pyrrolo[3′,4′:5,6]pyrido[2,3-d]pyrimidine-2,4,6,8(3H,7H)-tetraone and Selectively N7-Substituted Analogues through Key Synthons

Éric Merlet, P. Helissey, Stéphanie Desbène-Finck, 2015 .

Easy Access to 1H-Pyrrolo[3′,4′:5,6]pyrido[2,3-d]pyrimidine-2,4,6,8(3H,7H)-tetraone and Selectively N7-Substituted Analogues Through Key Synthons.

Éric Merlet, P. Helissey, Stéphanie Desbène-Finck, 2016 .

Assessing the potential leukemogenic effects of 50 Hz magnetic fields and their harmonics using an animal leukemia model.

M. Tanguy, C. Hubert, N. Bernard, 2008, Journal of radiation research.

Structure-mutagenicity relationships in series of 11H-indolo[3,2-c]quinoline-1,4-diones, tetrahydro-11H-indolo[3,2-c]quinoline-1,4-diones and 11H-pyrido[3',4':4,5]pyrrolo[3,2-c]quinoline-1,4-diones with leukemia cytotoxic properties. Relations with topoisomerase I inhibiting properties.

B. Festy, P. Helissey, S. Giorgi-Renault, 1994, Mutation research.

Alkylation of 5‐ and 6‐Methylindolo[2,3‐b]quinoxalines: Revised Structures of the N,N′‐Dimethylated Salts

P. Helissey, Stéphanie Desbène-Finck, S. Giorgi-Renault, 2005 .

2,3-bis(2-pyridyl)-5,8-quinoxalinediones with metal chelating properties: synthesis and biological evaluation.

J. Hénichart, P. Helissey, J. Bernier, 1989, Journal of pharmaceutical sciences.

Novel ferrocene-pyrazolo[1,5-a]pyrimidine hybrids: A facile environment-friendly regioselective synthesis, structure elucidation, and their antioxidant, antibacterial, and anti-biofilm activities

P. Helissey, J. N. Vishwakarma, J. D. Roy, 2022, Journal of Chemical Sciences.

Heterocyclic quinones. XVI. Pharmacomodulation in the series of 11H-indolo[3,2-c]quinolinediones: synthesis, cytotoxicity and antitumor activity of 3-substituted 11H-pyrido[3',4':4,5]pyrrolo[3,2-c]quinoline-1,4-diones.

P. Helissey, S. Giorgi-Renault, S. Cros, 1989, Chemical & pharmaceutical bulletin.

A convenient synthesis of 1H-pyrrolo[3,2-c]quinoline-6,9-diones and 11H-indolo[3,2-c]quinoline-1,4-diones derivatives.

H. Parrot-Lopez, P. Helissey, S. Cros, 1987, Chemical & pharmaceutical bulletin.

Synthesis and cytotoxic activity of 7-methoxy-1H-pyrrolo[3,2-c]-quinoline-6,9-dione and 3-methoxy-11H-indolo[3,2-c]quinoline-1,4-diones

H. Parrot-Lopez, P. Helissey, S. Cros, 1987 .

Heterocyclic quinones VIII. Synthesis and anti-neoplastic evaluation of 7-substituted-1H-pyrrolo[3,2-c]quinoline-6,9-diones and 3-substituted-11H-indolo[3,2-c]quinoline-1,4-diones

C. Paoletti, H. Parrot-Lopez, P. Helissey, 1987 .

Design of a Composite Ethidium–Netropsin–Anilinoacridine Molecule for DNA Recognition

Christian Bailly, Michelyne Haroun, C. Bailly, 2003, Chembiochem : a European journal of chemical biology.

L. I. Singha, P. Helissey, S. Kaping, 2016, Molecular Diversity.