M. Täger

发表

Dipeptidylpeptidase IV (DPIV) and alanyl-aminopeptidases (AAPs) as a new target complex for treatment of autoimmune and inflammatory diseases-proof of concept in a mouse model of colitis.

U. Lendeckel, S. Ansorge, U. Bank, 2006, Advances in experimental medicine and biology.

Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions.

S. Ansorge, U. Bank, D. Reinhold, 2011, Immunobiology.

Novel aspects of cellular action of dipeptidyl peptidase IV/CD26

A. Heimburg, S. Ansorge, A. Thielitz, 2011, Biological chemistry.

Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions

U. Lendeckel, A. Heimburg, G. Koch, 2009, Clinical chemistry and laboratory medicine.

CD26/dipeptidyl peptidase IV in lymphocyte growth regulation.

U. Lendeckel, F. Bühling, T. Kähne, 1997, Advances in experimental medicine and biology.

Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-β1 (TGF-β1) in stimulated mouse splenocytes and thymocytes

F. Bühling, S. Ansorge, U. Bank, 1997 .

The effect of anti-CD26 antibodies on DNA synthesis and cytokine production (IL-2, IL-10 and IFN-gamma) depends on enzymatic activity of DP IV/CD26.

U. Lendeckel, F. Bühling, T. Kähne, 1997, Advances in experimental medicine and biology.

Aspirin reduces endothelial cell senescence.

H. Schröder, S. Bode-Böger, J. Martens-Lobenhoffer, 2005, Biochemical and biophysical research communications.

Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging.

U. Lendeckel, S. Bode-Böger, A. Bukowska, 2006, Biochemical and biophysical research communications.

Thiol-inducing and immunoregulatory effects of flavonoids in peripheral blood mononuclear cells from patients with end-stage diabetic nephropathy.

S. Ansorge, M. Täger, Jörn Dietzmann, 2002, Free radical biology & medicine.

Endogenous Nitric Oxide Synthesis Inhibitor Asymmetric Dimethyl l-Arginine Accelerates Endothelial Cell Senescence

T. Thum, S. Bode-Böger, Bibiana Beckmann, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Erythropoietin increases asymmetric dimethylarginine in endothelial cells: role of dimethylarginine dimethylaminohydrolase.

S. Bode-Böger, J. Kielstein, J. Martens-Lobenhoffer, 2005, Journal of the American Society of Nephrology : JASN.

Evidence of a defective thiol status of alveolar macrophages from COPD patients and smokers. Chronic obstructive pulmonary disease.

T. Welte, T. Köhnlein, S. Ansorge, 2000, Free radical biology & medicine.

Membrane-bound proteindisulfide isomerase (PDI) is involved in regulation of surface expression of thiols and drug sensitivity of B-CLL cells.

S. Ansorge, M. Täger, U. Thiel, 1997, Experimental hematology.

Restoration of the cellular thiol status of peritoneal macrophages from CAPD patients by the flavonoids silibinin and silymarin

S. Ansorge, M. Täger, Jörn Dietzmann, 2001, Free radical research.

Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhances expression of FoxP3 and TGF-beta1 and ameliorates acute colitis in mice.

P. Malfertheiner, M. Vieth, M. Naumann, 2007, International journal of molecular medicine.

Assigning the phenotype of a natural regulatory T-cell to the human T-cell line, KARPAS-299.

U. Lendeckel, A. Bukowska, S. Ansorge, 2006, International journal of molecular medicine.

PETIR-001, a dual inhibitor of dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN), ameliorates experimental autoimmune encephalomyelitis in SJL/J mice

A. Heimburg, S. Ansorge, A. Thielitz, 2011, Biological chemistry.

Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice

U. C. Kühlmann, S. Ansorge, A. Thielitz, 2009, Clinical chemistry and laboratory medicine.

CD 26 , APN / CD 13 and related enzymes as regulators of T cell immunity : implications for experimental encephalomyelitis and multiple sclerosis

U. Lendeckel, S. Ansorge, A. Thielitz, 2007 .

Antioxidant and antiprotease status in peripheral blood and BAL fluid after cardiopulmonary bypass.

T. Welte, F. Bühling, S. Ansorge, 2001, Chest.

Overproduction of IL-7, IL-10 and TGF-β1 in Multiple Myeloma

F. Bühling, D. Reinhold, M. Täger, 1997 .

Outside or inside: role of the subcellular localization of DP4-like enzymes for substrate conversion and inhibitor effects

A. Heimburg, G. Koch, S. Ansorge, 2011, Biological chemistry.

Rapid pacing of embryoid bodies impairs mitochondrial ATP synthesis by a calcium-dependent mechanism--a model of in vitro differentiated cardiomyocytes to study molecular effects of tachycardia.

A. Goette, H. Klein, G. Keilhoff, 2006, Biochimica et biophysica acta.

γ-Glutamyl transpeptidase-cellular expression in populations of normal human mononuclear cells and patients suffering from leukemias

H. Gassen, A. Frey, M. Täger, 1995, Annals of Hematology.

Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia

F. Striggow, S. Ansorge, S. Wrenger, 2012, Journal of Neuroinflammation.

Insufficient endogenous redox buffer capacity may underlie neuronal vulnerability to cerebral ischemia and reperfusion

K. Reymann, F. Striggow, U. H. Schröder, 2012, Journal of neuroscience research.

DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis.

U. Lendeckel, S. Ansorge, A. Thielitz, 2008, Frontiers in bioscience : a journal and virtual library.

Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation.

U. Lendeckel, S. Ansorge, U. Bank, 2006, Advances in experimental medicine and biology.

Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/ CD13)--a novel approach for the treatment of inflammatory bowel disease.

U. Lendeckel, A. Heimburg, S. Ansorge, 2006, International immunopharmacology.

Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation.

U. Lendeckel, S. Ansorge, U. Bank, 2006, International immunopharmacology.

Expression of Opioid Receptor Subtypes and Their Ligands in Fibrillating Human Atria

A. Goette, C. Röcken, H. Klein, 2005, Pacing and clinical electrophysiology : PACE.

Dual Inhibition of Dipeptidyl Peptidase IV and Aminopeptidase N Suppresses Inflammatory Immune Responses

U. Lendeckel, S. Ansorge, U. Bank, 2007, Annals of the New York Academy of Sciences.

Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-beta 1 (TGF-beta 1) in stimulated mouse splenocytes and thymocytes.

F. Bühling, S. Ansorge, U. Bank, 1997, Immunology letters.

Extracellular cysteines define ectopeptidase (APN, CD13) expression and function

U. Lendeckel, M. Arndt, S. Ansorge, 2002, Free Radical Biology and Medicine.

Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia

F. Striggow, S. Ansorge, S. Wrenger, 2012, Journal of Neuroinflammation.

Effect of Telmisartan on Nitric Oxide–Asymmetrical Dimethylarginine System: Role of Angiotensin II Type 1 Receptor and Peroxisome Proliferator Activated Receptor γ Signaling During Endothelial Aging

U. Lendeckel, S. Bode-Böger, A. Bukowska, 2008, Hypertension.

Angiotensin II Type 1 Receptor and Peroxisome Proliferator Activated Receptor Asymmetrical Dimethylarginine System : Role of − Effect of Telmisartan on Nitric Oxide

U. Lendeckel, A. Bukowska, J. Martens-Lobenhoffer, 2008 .

Preclinical pilot study monitoring topical drug penetration and dermal bioavailability of a peptidase inhibitor from different galenic formulations into pig dermis, using cutaneous microdialysis

H. Gollnick, A. Heimburg, U. Bank, 2017, Clinical and experimental dermatology.

A molecular mechanism for the cleavage of a disulfide bond as the primary function of agonist binding to G-protein-coupled receptors based on theoretical calculations supported by experiments.

A. Golbraikh, U. Lendeckel, W. Brandt, 1999, European journal of biochemistry.