S. Gillis

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In vitro effects of recombinant interleukin 7 on growth and differentiation of bone marrow pro-B- and pro-T-lymphocyte clones and fetal thymocyte clones.

S. Takeda, S. Gillis, R. Palacios, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Interleukin 7 is a T-cell growth factor.

E. Shevach, G. M. Pereira, S. Gillis, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Effects of recombinant human IL-7 on blast cell proliferation in acute lymphoblastic leukemia.

A. Ganser, O. Ottmann, D. Hoelzer, 1990, Leukemia.

Synergistic myelopoietic actions in vivo after administration to mice of combinations of purified natural murine colony-stimulating factor 1, recombinant murine interleukin 3, and recombinant murine granulocyte/macrophage colony-stimulating factor.

D. Williams, H. Broxmeyer, G. Hangoc, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Human granulocyte-macrophage progenitors and their sensitivity to cytotoxins: analysis by limiting dilution.

J. Watson, P. Crosier, S. Gillis, 1987, Blood.

Characterization of the cell surface receptor for human granulocyte/macrophage colony-stimulating factor

D. Friend, L. Park, S. Gillis, 1986, The Journal of experimental medicine.

The influence of S17 stromal cells and interleukin 7 on B cell development

A. Cumano, K. Dorshkind, C. Paige, 1990, European journal of immunology.

Granulocyte-macrophage colony-stimulating factor: an effective adjuvant for protein and peptide-based vaccines

J. Gralow, M. Cheever, M. Disis, 1996 .

Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene.

D. Cerretti, D. Cosman, B. Gallis, 1988, Molecular immunology.

Recombinant granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid cancer.

J. Armitage, P. Bierman, J. Vose, 1991, The New England journal of medicine.

Glucocorticoid-induced inhibition of T cell growth factor production. I. The effect on mitogen-induced lymphocyte proliferation.

G. Crabtree, K. Smith, S. Gillis, 1979, Journal of immunology.

Interleukin-7 induces N-myc and c-myc expression in normal precursor B lymphocytes.

F. Alt, G. Yancopoulos, S. Gillis, 1992, Genes & development.

T-Cell lymphoma model for the analysis of interleukin 1-mediated T-cell activation.

S. Mizel, S. Gillis, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.

C. Janeway, E. Shevach, T. Malek, 1984, Journal of immunology.

Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line

J. Watson, Z. Gillis, S. Gillis, 1980, The Journal of experimental medicine.

The spleen focus-forming virus (SFFV)-specific neoantigen shares cross-reactive determinants with mink cell focus-inducing (MCF) virus gp70.

E. Scolnick, S. Ruscetti, K. Smith, 1979, Virology.

The detection of a spleen focus-forming virus neoantigen by lymphocyte- mediated cytolysis

S. Gillis, A. Gillis, KA Smith, 1978, The Journal of experimental medicine.

Binding, internalization, and intracellular localization of interleukin-1 beta in human diploid fibroblasts.

R. Page, S. Dower, E. Qwarnstrom, 1988, The Journal of biological chemistry.

The interleukin-1 receptor and post-receptor events

S. Dower, J. Sims, S. Gillis, 1989 .

Characterization of the cell surface receptor for granulocyte-macrophage colony-stimulating factor.

D. Friend, L. Park, S. Gillis, 1986, The Journal of biological chemistry.

Functional and molecular characteristics of T-cell growth factor.

K. Smith, F. Ruscetti, S. Gillis, 1980, Molecular immunology.

Cloning, sequence, and expression of bovine interferon-gamma.

D. Cerretti, D. Cosman, A. Larsen, 1986, Journal of immunology.

Cloning, sequence, and expression of bovine interleukin 2.

D. Cerretti, D. Cosman, A. Larsen, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Induction of macrophage tumoricidal activity by granulocyte-macrophage colony-stimulating factor.

V. Price, K. Grabstein, P. Conlon, 1986, Science.

Ecological and physiological aspects of tissue‐cultured plants

P. Debergh, J. Huylenbroeck, S. Gillis, 1992 .

The cell surface receptors for interleukin-1 alpha and interleukin-1 beta are identical.

T. Hopp, S. Dower, C. Henney, 1986, Nature.

IL-1 and IFN-gamma increase vascular permeability.

H. Kolb, S. Martin, S. Gillis, 1988, Immunology.

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

N. Copeland, N. Jenkins, G. Sutherland, 1993, Cell.

Soluble CD23 is released by B lymphocytes cycling in response to interleukin 4 and anti‐Bp50 (CDw40)

G. Guy, J. Ledbetter, J. Cairns, 1988, European journal of immunology.

Effects of interleukin-1 on hormone release from normal rat pituitary cells in primary culture.

A. Arimura, S. Gillis, A. Uehara, 1987, Neuroendocrinology.

Affinity Crosslinking and SDS-PAGE

T. Hopp, P. Conlon, S. Gillis, 2003 .

Detection and characterization of high affinity plasma membrane receptors for human interleukin 1

C. March, T. Hopp, S. Dower, 1985, The Journal of experimental medicine.

Understanding the dendritic cell lineage through a study of cytokine receptors

G. Schuler, N. Romani, E. Kämpgen, 1994, The Journal of experimental medicine.

IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-gamma.

H. Remold, S. Gillis, W. Weiser, 1989, Journal of immunology.

S. Dower, S. Gillis, D. Urdal, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Cytokine-dependent thymocyte responses: characterization of IL 1 and IL 2 target subpopulations and mechanism of action.

C. Henney, P. Conlon, S. Gillis, 1982, Journal of immunology.

Differential expression of secretory granule proteases in mouse mast cells exposed to interleukin 3 and c-kit ligand

K. Austen, N. Ghildyal, R. Stevens, 1992, The Journal of experimental medicine.

531 The effect of cytokines on human basophils

L. Lichtenstein, R. Schleimer, M. Plaut, 1988 .

Interleukin-1 is released at sites of human cutaneous allergic reactions.

L. Lichtenstein, C. Dinarello, R. Schleimer, 1990, The Journal of allergy and clinical immunology.

Beta transforming growth factors are potential regulators of B lymphopoiesis

R. Wall, P. Kincade, S. Gillis, 1987, The Journal of experimental medicine.

Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor.

D. Cerretti, V. Price, D. Cosman, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of IL-2-dependent cytotoxic T-cell clones. II. Cell-surface phenotypes, histochemical and ultrastructural properties.

M. Palladino, H. Oettgen, A. Carroll, 1983, Cellular immunology.

Ia-dependent interleukin 2 production in syngeneic cellular interactions.

O. Stutman, E. Lattime, S. Gillis, 1982, Journal of immunology.

Expression, purification and characterization of recombinant murine granulocyte-macrophage colony-stimulating factor and bovine interleukin-2 from yeast.

C. March, V. Price, D. Cosman, 1987, Gene.

Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines

C. March, T. Hopp, K. Grabstein, 1986, The Journal of experimental medicine.

Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines

C. March, T. Hopp, K. Grabstein, 1986, The Journal of experimental medicine.

Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor.

S. Dower, P. Morrissey, W. Fanslow, 1990, Science.

Normal B cell precursors responsive to recombinant murine IL-7 and inhibition of IL-7 activity by transforming growth factor-beta.

P. Kincade, S. Gillis, A. Namen, 1989, Journal of immunology.

The effect of T cell growth factor on the generation of cytolytic T cells.

Kendall A. Smith, K. Smith, S. Gillis, 1978, Journal of immunology.

Interleukin 2 administered in vivo induces the growth of cultured T cells in vivo.

J. Thompson, P. Greenberg, M. Cheever, 1984, Journal of immunology.

Molecular Characterization of Interleukin 2

J. Watson, M. B. Frank, C. Henney, 1982, Federation proceedings.

A comparative study of releasing and nonreleasing human basophils: nonreleasing basophils lack an early component of the signal transduction pathway that follows IgE cross-linking.

D. MacGlashan, S. Gillis, K. L. Nguyen, 1990, The Journal of allergy and clinical immunology.

Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds.

C. Dinarello, D. Proud, J. Hendley, 1994, The Journal of infectious diseases.

Preclinical studies and future directions in the development of new hematologic growth factors

S. Gillis, 1991, Breast Cancer Research and Treatment.

Influence of a recombinant human soluble tumor necrosis factor receptor FC fusion protein on type II collagen-induced arthritis in mice.

P. Wooley, S. Gillis, J. Dutcher, 1993, Journal of immunology.

Synergistic effects of purified recombinant human and murine B cell growth factor-1/IL-4 on colony formation in vitro by hematopoietic progenitor cells. Multiple actions.

D. Williams, H. Broxmeyer, L. Lu, 1988, Journal of immunology.

The effects of interleukin-2 (IL-2) on primary in vivo immune responses

P. Conlon, S. Hefeneider, S. Gillis, 1982 .

Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE).

S. Gendler, S. Gillis, D. Horwitz, 1983, Journal of immunology.

Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand.

K. Zsebo, A. Dvorak, L. Schwartz, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Expression of interleukin 2, interferon-gamma, and the IL 2 receptor by human peripheral blood lymphocytes.

K. Grabstein, S. Dower, A. Larsen, 1986, Journal of immunology.

Biochemical and biologic characterization of lymphocyte regulatory molecules. III. The isolation and phenotypic characterization of Interleukin-2 producing T cell lymphomas.

J. Watson, S. Gillis, M. Scheid, 1980, Journal of immunology.

The opposing actions in vivo on murine myelopoiesis of purified preparations of lactoferrin and the colony stimulating factors.

D. Williams, P. Ralph, H. Broxmeyer, 1987, Blood cells.

Lactoferrin: affinity purification from human milk and polymorphonuclear neutrophils using monoclonal antibody (II 2C) to human lactoferrin, development of an immunoradiometric assay using II 2C, and myelopoietic regulation and receptor-binding characteristics.

H. Broxmeyer, H. Broxmeyer, D. Bicknell, 1986, Blood cells.

Cytokine therapy: lessons learned and future challenges.

D. Williams, S. Gillis, D. Williams, 1998, Current opinion in immunology.

Localization of human mononuclear cell interleukin 1.

T. Hopp, K. Prickett, K. Grabstein, 1987, Journal of immunology.

Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens.

W. Paul, L. Glimcher, J. Bonventre, 1988, The Journal of molecular and cellular immunology : JMCI.

Recombinant human IL-1 alpha and -1 beta potentiate IgE-mediated histamine release from human basophils.

J. Warner, A. Kagey‐Sobotka, L. Lichtenstein, 1989, Journal of immunology.

Regulation of human basophil mediator release by cytokines. I. Interaction with antiinflammatory steroids.

L. Lichtenstein, D. MacGlashan, R. Schleimer, 1989, Journal of immunology.

Determination of the minimum polypeptide lengths of the functionally active sites of human interleukins 1 alpha and 1 beta.

D. Cosman, S. Dower, B. Mosley, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Enhancement by interleukin 4 of interleukin 2- or antibody-induced proliferation of lymphocytes from interleukin 2-treated cancer patients.

J. Thompson, P. Greenberg, J. Treisman, 1990, Cancer research.

Interleukin-1 stimulates proliferation of acute myeloblastic leukemia cells by induction of granulocyte-macrophage colony-stimulating factor release.

K. Kaushansky, B. Löwenberg, R. Delwel, 1989, Blood.

In vitro culture of common acute lymphoblastic leukemia blasts: effects of interleukin-3, interleukin-7, and accessory cells.

A. Ganser, D. Hoelzer, C. Bartram, 1992, Blood.

Human interleukin-7 induces proliferation of neoplastic cells from chronic lymphocytic leukemia and acute leukemias.

W. Digel, M. Schmid, G. Heil, 1991, Blood.

Monoclonal cytolytic T-cell lines

K. Smith, S. Gillis, P. Baker, 1979, The Journal of experimental medicine.

Molecular Modification of Lymphokines by in Vitro Mutagenesis

D. Cosman, S. Dower, A. Larsen, 1987, Annals of the New York Academy of Sciences.

High level stable expression of human interleukin-2 receptors in mouse cells generates only low affinity interleukin-2 binding sites.

D. Cerretti, D. Cosman, L. Park, 1986, Molecular immunology.

Human interleukin 3: effects on normal and leukemic cells.

J. Watson, K. Purdie, P. Crosier, 1989, Growth factors.

Induction of lymphokine-activated killer activity by interleukin 4 in human lymphocytes preactivated by interleukin 2 in vivo or in vitro.

J. Thompson, S. Gillis, A. Fefer, 1989, Cancer research.

In situ identification of cells in human leprosy granulomas with monoclonal antibodies to interleukin 2 and its receptor.

C. Taylor, F. Hofman, R. Modlin, 1984, Journal of immunology.

Granulocyte-macrophage colony-stimulating factor augments the primary antibody response by enhancing the function of antigen-presenting cells.

P. Morrissey, L. Park, L. Bressler, 1987, Journal of immunology.

Murine NK cell cultures: effects of interleukin-2 and interferon on cell growth and cytotoxic reactivity.

C. Henney, K. Kuribayashi, S. Gillis, 1981, Journal of immunology.

adjuvant for protein and peptide-based vaccines Granulocyte-macrophage colony-stimulating factor: an effective

J. Gralow, M. Cheever, S. Gillis, 2011 .

Granulocyte-macrophage colony-stimulating factor: an effective adjuvant for protein and peptide-based vaccines.

J. Gralow, M. Cheever, M. Disis, 1996, Blood.

Production of IL-1α and IL-1β by clones of EBV transformed, human B cells

A. Larsen, P. Conlon, S. Gillis, 1987 .

Myocarditis in tick-borne relapsing fever.

D. Wengrower, H. Knobler, S. Gillis, 1984, The Journal of infectious diseases.

Forced Diuresis and High Dosage Folinic Acid for the Treatment of Severe Methotrexate Toxicity

Y. Haviv, S. Gillis, 2000 .

Mechanisms of glucocorticoid-induced immunosuppression: inhibitory effects on expression of Fc receptors and production of T-cell growth factor.

G. Crabtree, K. Smith, A. Munck, 1980, Journal of steroid biochemistry.

Induction of IL 2 responsiveness in a murine IL 3-dependent cell line.

J. Watson, S. Gillis, G. le Gros, 1985, Journal of immunology.

Regulation of Human T‐Cell Proliferation and CTL Development by Human Recombinant Interleukin‐4

K. Grabstein, S. Gillis, M. Widmer, 1988, Annals of the New York Academy of Sciences.

Interleukin 4 (BSF‐1) induces growth in resting murine CD8 T cells triggered via cross‐linking of T3 cell surface structures

K. Heeg, H. Wagner, T. Miethke, 1988, European journal of immunology.

Long-term culture of human antigen-specific cytotoxic T-cell lines

K. Smith, F. Ruscetti, S. Gillis, 1978, The Journal of experimental medicine.

Stimulation of myelopoiesis in patients with aplastic anemia by recombinant human granulocyte-macrophage colony-stimulating factor.

J. Gutterman, W. Hittelman, H. Broxmeyer, 1988, The New England journal of medicine.

IN VIVO INTERLEUKIN-2 INDUCED AUGMENTATION OF NATURAL KILLER CELL ACTIVITY

C. Henney, S. Hefeneider, S. Gillis, 1982 .

Induction of antibody responses to influenza virus in human lymphocyte cultures. I. Role of interleukin 2.

R. Booth, J. Watson, S. Dower, 1985, Journal of immunology.

Inhibition of interleukin 4‐promoted CD23 production in human B lymphocytes by transforming growth factor‐β, interferons or anti‐CD19 antibody is overriden on engaging CD40

J. Gordon, S. Gillis, A. Katira, 1991, European journal of immunology.

In a concerted action kit ligand and interleukin 3 control the synthesis of serotonin in murine bone marrow-derived mast cells. Up-regulation of GTP cyclohydrolase I and tryptophan 5-monooxygenase activity by the kit ligand.

B. Kempkes, R. Mailhammer, L. Hültner, 1993, The Journal of biological chemistry.

Interleukin 2 is not sufficient for the continuous growth of cloned NK-like cytotoxic cell lines.

C. Henney, S. Gillis, C. Brooks, 1983, Journal of immunology.

Interleukin 2 induces gamma-interferon production: participation of macrophages and NK-like cells.

I. Kawase, W. Newman, C. Henney, 1983, Journal of immunology.

Human interleukin 4 regulates the phenotype of lymphocytes generated during mixed lymphocyte culture and inhibits the IL-2-induced development of LAK function in normal and leukaemic cells.

M. Vadas, G. Burns, C. Juttner, 1989, Leukemia research.

A novel regulatory myosin light chain gene distinguishes pre‐B cell subsets and is IL‐7 inducible.

F. Alt, A. Rolink, F. Melchers, 1992, The EMBO journal.

Purification and chemical characterization of the receptor for interleukin 2 from activated human T lymphocytes and from a human T-cell lymphoma cell line.

C. March, S. Dower, A. Larsen, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Immunopharmacologic Approaches to Delineation of the Mechanism of Cell-Mediated Cytotoxicity Using Cytotoxic T Cell Clones

M. Palladino, M. Plaut, C. Henney, 1981 .

Effects of recombinant growth factors on radiation survival of human bone marrow progenitor cells.

C. Song, F. Uckun, S. Gillis, 1989, International journal of radiation oncology, biology, physics.

The in vivo effects of interleukin 1. I. Bone marrow cells are induced to cycle after administration of interleukin 1.

R. Neta, M. Sztein, J. Oppenheim, 1987, Journal of immunology.

effects of interleukin-3, interleukin-7, and accessory cells In vitro culture of common acute lymphoblastic leukemia blasts:

A. Ganser, D. Hoelzer, S. Gillis, 2011 .

Interleukin 4 and soluble CD23 as progression factors for human B lymphocytes: analysis of their interactions with agonists of the phosphoinositide “dual pathway” of signalling

G. Guy, J. Cairns, J. Gordon, 1988, European journal of immunology.

Glucocorticoid-induced inhibition of T cell growth factor production. II. The effect on the in vitro generation of cytolytic T cells.

G. Crabtree, K. Smith, S. Gillis, 1979, Journal of immunology.

In vivo interleukin 2 administration augments the generation of alloreactive cytolytic T lymphocytes and resident natural killer cells.

C. Henney, P. Conlon, S. Hefeneider, 1983, Journal of immunology.

cell transplantation alone and in combination, after allogeneic murine hematopoietic stem CSF), granulocyte-macrophage CSF, interleukin-1 (IL-1), and IL-4, In vivo administration of granulocyte colony-stimulating factor (G-

K. Atkinson, S. Gillis, J. Biggs, 2013 .

In vivo administration of granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage CSF, interleukin-1 (IL-1), and IL-4, alone and in combination, after allogeneic murine hematopoietic stem cell transplantation.

K. Atkinson, S. Gillis, J. Biggs, 1991, Blood.

Modulation of Neonatal Myelopoiesis in Newborn Rats after 7 Days' Administration of Either Granulocyte-Monocyte Colony Stimulating Factor or Interleukin-3

M. Cairo, S. Gillis, C. Ven, 1991, Pediatric Research.

Serological visualization of interleukin 2.

P. Conlon, S. Hefeneider, S. Gillis, 1983, Science.

The role of interleukin-2 (IL-2) in the differentiatin of cytotoxic T cells: the effect of monoclonal anti-IL-2 antibody and absorption with IL-2 dependent T cell lines.

C. Henney, S. Gillis, M. Okada, 1981, Journal of immunology.

Monoclonal antibody directed against interleukin 2. I. Inhibition of T lymphocyte mitogenesis and the in vitro differentiation of alloreactive cytolytic T cells

C. Henney, S. Gillis, A. Gillis, 1981, The Journal of experimental medicine.

The in vitro generation and sustained culture of nude mouse cytolytic T- lymphocytes

Kendall A. Smith, K. Smith, S. Gillis, 1979, The Journal of experimental medicine.

Generation of alloreactive cytotoxic T lymphocytes: evidence for a differentiation factor distinct from IL 2.

J. Finke, M. Hilfiker, J. Scott, 1983, Journal of immunology.

T‐CELL GROWTH FACTOR‐MEDIATED T‐CELL PROLIFERATION *

Kendall A. Smith, F. Ruscetti, S. Gillis, 1979, Annals of the New York Academy of Sciences.

Interleukin-2 induction of hapten-specific cytolytic T cells in nude mice.

J. Watson, S. Gillis, 1981, Journal of immunology.

In vitro transformation by Epstein‐Barr virus induces a switch in growth factor and anti‐IgM responsiveness in a human leukemic B cell clone

O. Janssen, D. Kabelitz, S. Gillis, 1990, European journal of immunology.

Cloning, sequence and expression of bovine interleukin 1α and interleukin 1β complementary DNAs

D. Cerretti, C. Maliszewski, D. Cosman, 1988 .

In vitro generation of tumor-specific cytotoxic lymphocytes. Secondary allogeneic mixed tumor lymphocyte culture of normal murine spleen cells

S. Gillis, KA Smith, 1977, The Journal of experimental medicine.

A novel mast cell growth factor (MCGF-3) produced by marrow-adherent cells that synergizes with interleukin 3 and interleukin 4.

D. Williams, G. Burgess, H. Boswell, 1990, Experimental hematology.

Lymphokine purification by reversed-phase high-performance liquid chromatography.

M. L. Remerowski, C. March, P. Conlon, 1984, Journal of chromatography.

Interleukin 2, production in the syngeneic mixed lymphocyte reaction

C. David, O. Stutman, E. Lattime, 1981, European journal of immunology.

Biochemical and biological characterization of lymphocyte regulatory molecules. I. Purification of a class of murine lymphokines

J. Watson, K. Smith, S. Gillis, 1979, The Journal of experimental medicine.

Limiting dilution analysis of interleukin 2 and colony-stimulating factor producer cells in normal and autoimmune mice.

C. Henney, S. Dower, P. Conlon, 1984, Journal of immunology.

Cellular interactions in marrow-grafted patients. I. Impairment of cell-mediated lympholysis associated with graft-vs-host disease and the effect of interleukin 2.

R. Storb, E. Thomas, T. Mori, 1983, Journal of immunology.

Regulation of resting and cycling human B lymphocytes via surface IgM and the accessory molecules interleukin-4, CD23 and CD40.

J. Gordon, S. Gillis, L. Flores-Romo, 1989, Immunology.

T cell growth factor: parameters of production and a quantitative microassay for activity.

Kendall A. Smith, K. Smith, S. Gillis, 1978, Journal of immunology.

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

C. March, T. Hopp, D. Cerretti, 1985, Nature.

Interleukin-2 augments natural killer cell activity

C. Henney, K. Kuribayashi, S. Gillis, 1981, Nature.

Long term culture of tumour-specific cytotoxic T cells

Kendall A. Smith, S. Gillis, Kendall A. Smith, 1977, Nature.

Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans.

M. Weksler, S. Gillis, R. Kozak, 1981, The Journal of clinical investigation.

The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor.

Comeau, D. Friend, C. Thut, 1992, Science.

Augmentation of the anti-tumor therapeutic efficacy of long-term cultured T lymphocytes by in vivo administration of purified interleukin 2

P. Greenberg, M. Cheever, S. Gillis, 1982, The Journal of experimental medicine.

Biochemical and biologic characterization of lymphocyte regulatory molecules. IV. Purification of Interleukin 2 from a murine T cell lymphoma.

J. Watson, S. Gillis, D. Mochizuki, 1980, Journal of immunology.

Biochemical characterization of lymphocyte regulatory molecules. II. Purification of a class of rat and human lymphokines.

J. Watson, K. Smith, S. Gillis, 1980, Journal of immunology.

The Interleukins

R. Reisfeld, H. Eisen, S. Gillis, 1985, Springer US.

Bovine GM-CSF: molecular cloning and biological activity of the recombinant protein.

D. Cerretti, C. Maliszewski, D. Cosman, 1988, Molecular immunology.

Interleukin‐2 Dependent Culture of Cytolytic T Cell Lines

S. Gillis, J. Watson, 1981, Immunological reviews.

The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor.

K. Prickett, D. Cosman, S. Dower, 1987, The Journal of biological chemistry.

The cell surface receptors for interleukin-1α and interleukin-1β are identical

T. Hopp, S. Dower, C. Henney, 1986, Nature.

Cloning, sequence and expression of human interleukin-2 receptor

C. March, S. Dower, D. Cerretti, 1984, Nature.

Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice.

D. Williams, H. Broxmeyer, A. Waheed, 1987, The Journal of clinical investigation.

Purification to homogeneity of a human hematopoietic growth factor that stimulates the growth of a murine interleukin 3-dependent cell line.

J. Watson, C. March, P. Crosier, 1986, Journal of immunology.

Stimulation of B-cell progenitors by cloned murine interleukin-7

C. March, R. Goodwin, D. Cosman, 1988, Nature.

Enhanced survival but reduced engraftment in murine recipients of recombinant granulocyte/macrophage colony-stimulating factor following transplantation of T-cell-depleted histoincompatible bone marrow.

B. Blazar, D. Vallera, S. Gillis, 1988, Blood.

Particle concentration fluorescence immunoassay for measuring interleukin-6 receptor numbers.

S. Gillis, D. Matheson, L. J. Hart, 1991, Cytokine.

Expression of functional human interleukin‐2 receptors in murine interleukin‐3‐dependent cells

S. Gillis, M. Eszes, E. Leung, 1988, Immunology and cell biology.

Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

R. Goodwin, D. Cosman, S. Lupton, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Glucocorticoids and immune responses.

G. Crabtree, K. Smith, A. Munck, 1979, Arthritis and rheumatism.

Stimulation of B-chronic lymphocytic leukemia populations by recombinant interleukin-4 and other defined growth-promoting agents.

N. Ling, S. Gillis, J. Gordon, 1988, Leukemia.

Purification to homogeneity and partial characterization of interleukin 2 from a human T-cell leukemia.

S. Gillis, D. Urdal, R. Blacher, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Effect of infection with murine recombinant retroviruses containing the v-src oncogene on interleukin 2- and interleukin 3-dependent growth states.

J. Watson, P. Conlon, S. Gillis, 1987, Journal of immunology.

The effects of purified recombinant murine interleukin-3 and/or purified natural murine CSF-1 in vivo on the proliferation of murine high- and low-proliferative potential colony-forming cells: demonstration of in vivo synergism.

D. Williams, H. Broxmeyer, A. Waheed, 1987, Blood.

Biochemical comparison of murine colony-stimulating factors secreted by a T cell lymphoma and a myelomonocytic leukemia.

J. Watson, P. Conlon, S. Gillis, 1984, Journal of immunology.

Immunoglobulin isotype production by cycling human B lymphocytes in response to recombinant cytokines and anti-IgM.

J. Gordon, S. Gillis, C. Sykes, 1990, Immunology.

Regulation of antibody production in vitro by granulocyte-macrophage colony stimulating factor.

V. Price, D. Cosman, K. Grabstein, 1986, The Journal of molecular and cellular immunology : JMCI.

murine recipients by granulocyte/macrophage colony-stimulating factor Augmentation of donor bone marrow engraftment in histoincompatible

B. Blazar, D. Vallera, S. Gillis, 2011 .

Augmentation of donor bone marrow engraftment in histoincompatible murine recipients by granulocyte/macrophage colony-stimulating factor.

B. Blazar, D. Vallera, L., 1988, Blood.

Stimulation of neutrophil production in CSF-1-responsive clones.

D. Lynch, S. Rhondeau, R. Christensen, 1988, Blood.

Cellular interactions in marrow-grafted patients. III. Normal interleukin 1 and defective interleukin 2 production in short-term patients and in those with chronic graft-versus-host disease.

R. Storb, E. Thomas, T. Mori, 1985, Transplantation.

Ineffective cellular interaction and interleukin 2 deficiency causing T cell defects in human allogeneic marrow recipients early after grafting and in those with chronic graft-versus-host disease.

R. Storb, E. Thomas, T. Mori, 1984, Transplantation proceedings.

T-cell growth factors: interleukin 2.

J. Watson, S. Gillis, D. Mochizuki, 1980, Immunology today.

Bone marrow stromal cells and interleukin-7 induce coordinate expression of the BP-1/6C3 antigen and pre-B cell growth.

M. Cooper, S. Gillis, A. Namen, 1990, International immunology.

a TRANSFORMING GROWTH FACTORS ARE POTENTIAL REGULATORS OF B LYMPHOPOIESIS BY

R. Wall, P. Kincade, S. Gillis, 2022 .

Changes in surface antigens of immature thymocytes under the influence of T-cell growth factor and thymic factors.

S. S. Chen, R. Good, J. Hadden, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Biochemical and Biological Characterization of Lymphocyte Regulatory Molecules I. Purification of a Class of Murine Lymphokines*

M. Thoman, S. Gillis, J. Marbrook, 1980 .

INTERLEUKIN-2 AND THE REGULATION OF CYTOTOXIC CELLS

C. Henney, S. Gillis, D. Kern, 1983 .

Biochemical separation of interleukin 2.

J. Watson, S. Gillis, D. Mochizuki, 1980, Journal of immunological methods.

T-CELL GROWTH FACTOR DEPENDENT RESTORATION OF NUDE MOUSE T-CELL MITOGENESIS AND ALLOANTIGEN REACTIVITY

Kendall A. Smith, S. Gillis, P. Baker, 1979 .

The human recombinant c-kit receptor ligand, rhSCF, induces mediator release from human cutaneous mast cells and enhances IgE-dependent mediator release from both skin mast cells and peripheral blood basophils.

S. Galli, K. Zsebo, L. Lichtenstein, 1992, Journal of immunology.

The treatment of induced immune deficiency with interleukin-2.

C. Henney, P. Conlon, S. Gillis, 1985, Immunology letters.

Cytokine-dependent thymocyte responses. II. Generation of cytotoxic T lymphocytes from immature thymocytes.

C. Henney, P. Conlon, S. Gillis, 1982, Journal of immunology.

Display of the neutral glycolipid ganglio-n-tetraosylceramide (asialo GM1) on cells of the natural killer and T lineages.

C. Henney, S. Gillis, B. N. Beck, 1982, Transplantation.

Interleukin 2: Biology and biochemistry

S. Gillis, 2004, Journal of Clinical Immunology.

3 – Biochemical Characterization of Interleukin-2 (T Cell Growth Factor)

J. Watson, S. Gillis, D. Mochizuki, 1982 .

Differential bioassay of interleukin 2 and interleukin 4.

S. Ho, R. Abraham, S. Gillis, 1987, Journal of immunological methods.

IL-4 bypasses the immune suppressive effect of cyclosporin A during the in vitro induction of murine cytotoxic T lymphocytes.

K. Heeg, H. Wagner, S. Gillis, 1988, Journal of immunology.

The biochemical and biological characterization of lymphocyte regulatory molecules. VI. Generation of a B cell hybridoma whose antibody product inhibits interleukin 2 activity.

C. Henney, S. Gillis, 1981, Journal of Immunology.

Characterization of the cell surface receptor for a multi-lineage colony-stimulating factor (CSF-2 alpha).

D. Friend, L. Park, S. Gillis, 1986, The Journal of biological chemistry.

Molecular Characterization of Colony‐ Stimulating Factors and Their Receptors: Human Interleukin‐3

V. Price, D. Cosman, L. Park, 1989, Annals of the New York Academy of Sciences.

The effects in vivo of purified preparations of murine macrophage colony stimulating factor-1, recombinant murine granulocyte-macrophage colony stimulating factor and natural and recombinant murine interleukin 3 without and with pretreatment of mice with purified iron-saturated human lactoferrin.

D. Williams, A. Waheed, H. Boswell, 1986, Immunobiology.

Molecular characterization of interleukin 2 produced from tumor cell lines and T cell hybridomas.

S. Gillis, D. Mochizuki, 1982, Current topics in microbiology and immunology.

Regulation of the interleukin 4 signal in human B-lymphocytes.

R. Michell, S. Gillis, M. Finney, 1991, Biochemical Society transactions.

533 Human recombinant interleukin 3 (IL3) induces histamine release from human basophils

A. Kagey‐Sobotka, L. Lichtenstein, S. Gillis, 1988 .

Isolation of murine fetal thymus cell lines after infection with recombinant retroviruses containing the v-myc and v-Ha-ras oncogenes.

J. Watson, P. Crosier, S. Gillis, 1989, Journal of immunology.

Interleukins: a rose is a rose ….

S. Gillis, 1982, Immunology today (Amsterdam. Regular ed.).

Recombinant IL-3 induces histamine release from human basophils.

A. Kagey‐Sobotka, L. Lichtenstein, R. Schleimer, 1989, Journal of immunology.

Interactions between purified murine colony-stimulating factors (natural CSF-1, recombinant GM-CSF, and recombinant IL-3) on the in vitro proliferation of purified murine granulocyte-macrophage progenitor cells.

D. Williams, H. Broxmeyer, A. Waheed, 1987, Experimental hematology.

Factors for success in biotechnology: Then and now

S. Gillis, 1998, Nature Biotechnology.

Recombinant interleukin-7 supports the growth of normal B lymphocyte precursors.

P. Kincade, S. Gillis, A. Namen, 1988, Current topics in microbiology and immunology.

IL-4 potentiates the IL-2-dependent proliferation of mouse cytotoxic T cells.

V. Paetkau, J. Hooton, S. Gillis, 1990, Journal of immunology.

Autologous mixed lymphocyte reaction in man. XIV. Deficiency of the autologous mixed lymphocyte reaction in acquired immune deficiency syndrome (AIDS) and AIDS related complex (ARC). In vitro effect of purified interleukin-1 and interleukin-2.

S. Gupta, S. Gillis, M. Thornton, 1984, Clinical and experimental immunology.

Molecular characterization of interleukin 2.

J. Watson, M. B. Frank, C. Henney, 1982, Immunological reviews.

The inhibition of in vivo tumor growth by cytotoxic t-cell lines. Abstr.

K. Smith, S. Gillis, P. Baker, 1979 .

Hematopoietic growth factors in human serum. erythroid burst-promoting activity in normal subjects and in patients with severe aplastic anemia.

J. Adamson, Y. Yen, S. Gillis, 1985, The Journal of laboratory and clinical medicine.

Cytotoxic responses: the regulatory influence of interleukin-2.

C. Henney, S. Gillis, D. Kern, 1982, Transplantation Proceedings.

Ex vivo expansion of peripheral blood progenitor cells with recombinant cytokines.

D. Williams, M. Teepe, S. Gillis, 1992, Experimental hematology.

Reversal of phorbol ester-mediated reduction of cloned T lymphocyte cytolysis by interleukin 2.

C. Orosz, J. Finke, J. Scott, 1985, Journal of Immunology.

In vivo treatment with IL-1 reduces the severity and duration of antigen-induced arthritis in rats.

G. Callis, C. Jacobs, P. Conlon, 1988, Journal of immunology.

In vitro and in vivo cytokine-induced facilitation of immunohematopoietic reconstitution in mice undergoing bone marrow transplantation.

A. Landesberg, E. Kedar, S. Slavin, 1988, Bone marrow transplantation.

Production of recombinant human colony stimulating factors in yeast.

V. Price, D. Cosman, S. Gillis, 1988, Behring Institute Mitteilungen.

Lymphokines: from conjecture to the clinic.

T. Hopp, V. Price, D. Cosman, 1986, Seminars in oncology.

Constitutive production of interleukin 2 activity by a T cell hybridoma.

S. Gillis, D. Stull, 1981, Journal of immunology.

Definition of T cell idiotypes using anti-idiotypic antisera produced by immunization with T cell clones

C. Fathman, S. Gillis, A. Infante, 1982, The Journal of experimental medicine.

Long-term follow-up of a phase III study of recombinant human granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid malignancies.

P. Bierman, J. Vose, D. Neuberg, 1993, Blood.

Glucocorticoid-Induced Inhibition of T Cell Growth Factor Production

G. Crabtree, Kendall A. Smith, S. Gillis, 1979, The Journal of Immunology.

Glucocorticoid-induced inhibition of T cell growth factor production. II. The effect on the in vitro generation of cytolytic T cells.

G. Crabtree, K. Smith, S. Gillis, 1979, Journal of immunology.

T-cell growth factor (Interleukin 2) and terminal transferase activity in human leukemias and lymphoblastic cell lines

R. Mertelsmann, P. Ralph, M. Moore, 1981, Blut.

Changes in surface antigens of immature thymocytes under the influence of interleukin II and thymic factors

S. S. Chen, R. Good, J. Hadden, 1982 .

Effects of interleukin-4 on the in vitro growth of human lymphoid and plasma cell neoplasms.

T. Grogan, C. Taylor, S. Salmon, 1990, Blood.

Effect of Recombinant Human c-kit Receptor Ligand on Mediator Release from Human Skin Mast Cells.

S. Galli, K. Zsebo, L. Lichtenstein, 1992, International Archives of Allergy and Immunology.

Characterization of the cell surface receptor for human granulocyte/macrophage colony-stimulating factor

D. Friend, L. Park, S. Gillis, 1986, The Journal of experimental medicine.

chronic lymphocytic leukemia and acute leukemias Human interleukin-7 induces proliferation of neoplastic cells from

W. Digel, M. Schmid, G. Heil, 2011 .

Effect of in vivo administration of IL-3 and IL-6, alone and in combination with G-CSF, GM-CSF or IL-1, on haematopoiesis, graft-versus-host disease and survival after murine haematopoietic stem cell transplantation.

K. Atkinson, S. Gillis, A. Guiffre, 1995, Cytokines and molecular therapy.

S. Gillis, J. Biggs, A. Guiffre, 1991, Blood.

Interleukin biochemistry and biology: summary and introduction.

S. Gillis, 1983, Federation proceedings.

Hematopoietic growth-factor receptors.

L. Park, S. Gillis, D. Urdal, 1990, Immunology series.