O. Marcos-Contreras

发表

Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE)

Rachel S. Riley, D. Weissman, V. Muzykantov, 2021, Journal of Controlled Release.

Bivalent engagement of endothelial surface antigens is critical to prolonged surface targeting and protein delivery in vivo

C. Villa, V. Muzykantov, C. Greineder, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1)

C. Villa, V. Muzykantov, C. Greineder, 2018, Scientific Reports.

Dual Affinity to RBCs and Target Cells (DART) Enhances Both Organ- and Cell Type-Targeting of Intravascular Nanocarriers.

S. Mitragotri, E. Morrisey, C. Villa, 2022, ACS nano.

Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation.

V. Muzykantov, J. Atkinson, M. Poncz, 2010, Blood.

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude

Samir Mitragotri, Vladimir Muzykantov, Hamideh Parhiz, 2018, Nature Communications.

Combining vascular targeting and the local first pass provides 100‐fold higher uptake of ICAM‐1‐targeted vs untargeted nanocarriers in the inflamed brain

C. Villa, V. Muzykantov, C. Greineder, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Hyperfibrinolysis increases blood-brain barrier permeability by a plasmin- and bradykinin-dependent mechanism.

J. Montaner, D. Vivien, Antoine Anfray, 2016, Blood.

Gene-based FVIIa prophylaxis modulates the spontaneous bleeding phenotype of hemophilia A rats.

P. Gimotty, P. Margaritis, M. Kjelgaard‐Hansen, 2019, Blood advances.

Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles

V. Muzykantov, M. Grady, C. Greineder, 2018, Advanced materials.

Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps

V. Torchilin, K. Rostamizadeh, J. Myerson, 2020, mAbs.

Targeted In Vivo Loading of Red Blood Cells Markedly Prolongs Nanocarrier Circulation.

C. Villa, V. Muzykantov, C. Greineder, 2022, Bioconjugate chemistry.

Ultra-Sensitive Molecular MRI of Vascular Cell Adhesion Molecule-1 Reveals a Dynamic Inflammatory Penumbra After Strokes

D. Vivien, E. Maubert, M. Gauberti, 2013, Stroke.

Molecularly Engineered Nanobodies for Tunable Pharmacokinetics and Drug Delivery.

C. Villa, V. Muzykantov, C. Greineder, 2020, Bioconjugate chemistry.

The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo.

P. Margaritis, L. Ivanciu, O. Marcos-Contreras, 2014, Blood.

Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII.

P. Margaritis, D. Bellinger, T. Nichols, 2016, Blood.

GENE THERAPY Sustained correction of FVII de ﬁ ciency in dogs using AAV-mediated expression of zymogen FVII

P. Margaritis, D. Bellinger, T. Nichols, 2016 .

Cross-linker-Modulated Nanogel Flexibility Correlates with Tunable Targeting to a Sterically Impeded Endothelial Marker.

V. Muzykantov, D. Eckmann, R. Composto, 2019, ACS nano.

Supramolecular Arrangement of Protein in Nanoparticle Structures Predicts Nanoparticle Tropism for Neutrophils in Acute Lung Inflammation

V. Rotello, J. Lahann, S. Mitragotri, 2021, Nature Nanotechnology.

Combating Complement's Deleterious Effects on Nanomedicine by Conjugating Complement Regulatory Proteins to Nanoparticles

V. Muzykantov, Jia Nong, J. Myerson, 2021, Advanced materials.

Supramolecular Organization Predicts Protein Nanoparticle Delivery to Neutrophils for Acute Lung Inflammation Diagnosis and Treatment

V. Rotello, J. Lahann, S. Mitragotri, 2020, bioRxiv.

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude

J. Lahann, S. Mitragotri, C. Villa, 2018, Nature Communications.

Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier

C. Villa, V. Muzykantov, C. Greineder, 2020, Proceedings of the National Academy of Sciences.

Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1)

C. Villa, V. Muzykantov, C. Greineder, 2018, Scientific Reports.

Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage.

S. Kasner, V. Muzykantov, L. Sansing, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Targeted nanocarriers coopting pulmonary leukocytes for drug delivery to the injured brain

D. Weissman, S. Kasner, C. Villa, 2022, bioRxiv.

Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9

C. Villa, V. Muzykantov, C. Greineder, 2018, Scientific Reports.

Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain.

D. Weissman, S. Kasner, C. Villa, 2023, ACS nano.

Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions

Jia Nong, J. Myerson, Zhicheng Wang, 2023, bioRxiv.

Effective Prevention of Arterial Thrombosis with Albumin-Thrombin Inhibitor Conjugates.

V. Muzykantov, Jia Nong, J. Myerson, 2023, Molecular Pharmaceutics.

Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9

C. Villa, V. Muzykantov, C. Greineder, 2018, Scientific Reports.

Clot penetration and retention by plasminogen activators promote fibrinolysis.

R. Shlansky-Goldberg, V. Muzykantov, D. Cines, 2013, Biochemical pharmacology.

Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke

D. Weissman, S. Kasner, V. Muzykantov, 2023, bioRxiv.

Combination of Physicochemical Tropism and Affinity Moiety Targeting of Lipid Nanoparticles Enhances Organ Targeting.

J. Myerson, J. Brenner, Marco E. Zamora, 2024, Nano letters.

Arteriosclerosis, Thrombosis, and Vascular Biology

T. Grosser, E. Ricciotti, R. Lordan, 2022 .