Hannah-Lena Obermann

RNA-Cholesterol Nanoparticles Function as Potent Immune Activators via TLR7 and TLR8

U. Bakowsky, A. Kaufmann, L. Sander, 2022, Frontiers in Immunology.

RNA-DNA hybrids and ssDNA differ in intracellular half-life and toll-like receptor 9 activation.

A. Kaufmann, S. Bauer, Hannah-Lena Obermann, 2019, Immunobiology.

Toll-like receptor 9, what o'clock is it?

S. Bauer, Hannah-Lena Obermann, 2012, Immunity.

Identification of an Optimal TLR8 Ligand by Alternating the Position of 2′-O-Ribose Methylation

Stephanie Jung, E. Bartok, Hannah-Lena Obermann, 2022, International journal of molecular sciences.

A ribosomal RNA fragment with 2′,3′-cyclic phosphate and GTP-binding activity acts as RIG-I ligand

Leon N. Schulte, F. Weber, A. Kaufmann, 2020, Nucleic acids research.

IRF9 Prevents CD8+ T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection

M. Huber, T. Strecker, H. Raifer, 2017, Journal of Virology.

ADAR1 Is Required for Dendritic Cell Subset Homeostasis and Alveolar Macrophage Function

A. Goesmann, A. Gruber, O. Rupp, 2019, The Journal of Immunology.

TLR8 is activated by 5'-methylthioinosine, a Plasmodium falciparum-derived intermediate of the purine salvage pathway.

H. Heine, Thomas Müller, A. Kaufmann, 2022, Cell reports.