T. Beissert

发表

Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses

U. Şahin, D. Busse, J. Tregoning, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells.

S. Boehrer, O. Ottmann, D. Hoelzer, 2005, Cancer research.

sensitivity to STI571 interferes with the transformation potential of BCR/ABL and increases Targeting of the N-terminal coiled coil oligomerization interface of BCR

S. Boehrer, A. Bianchini, C. Nervi, 2013 .

Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571.

S. Boehrer, A. Bianchini, C. Nervi, 2003, Blood.

progenitor cells translocation products by increasing the self-renewal of very primitive -Catenin contributes to leukemogenesis induced by AML-associated γ

R. Henschler, S. Boehrer, O. Ottmann, 2013 .

Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells.

R. Henschler, S. Boehrer, O. Ottmann, 2004, Blood.

Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis

O. Ottmann, D. Hoelzer, S. Güller, 2003, Oncogene.

A Trans-amplifying RNA Vaccine Strategy for Induction of Potent Protective Immunity.

Ö. Türeci, U. Şahin, Stephanie Erbar, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Improvement of In Vivo Expression of Genes Delivered by Self-Amplifying RNA Using Vaccinia Virus Immune Evasion Proteins

Ö. Türeci, U. Şahin, M. Diken, 2017, Human gene therapy.

T-cell receptor transfer into human T cells with ecotropic retroviral vectors

Ö. Türeci, U. Şahin, T. Beissert, 2014, Gene Therapy.

The gatekeeper mutation T315I confers resistance against small molecules by increasing or restoring the ABL-kinase activity accompanied by aberrant transphosphorylation of endogenous BCR, even in loss-of-function mutants of BCR/ABL

O. Ottmann, M. Ruthardt, T. Beissert, 2009, Leukemia.

Targeting of the N‐terminal coiled coil oligomerization interface by a helix‐2 peptide inhibits unmutated and imatinib‐resistant BCR/ABL

C. Nervi, M. Ruthardt, T. Beissert, 2008, International journal of cancer.

Targeting the Oligomerization of BCR/ABL by Membrane Permeable Competitive Peptides Inhibits the Proliferation of Philadelphia ChromosomePositive Leukemic Cells

A. Goldblum, O. Ottmann, J. Mahajna, 2011 .

The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.

S. Boehrer, C. Nervi, O. Ottmann, 2005, Cancer research.

Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells.

R. Henschler, D. Hoelzer, M. Ruthardt, 2007, Haematologica.

A Bivalent Trans-Amplifying RNA Vaccine Candidate Induces Potent Chikungunya and Ross River Virus Specific Immune Responses

U. Şahin, B. Schnierle, Mario Perković, 2022, Vaccines.

AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.

P. Pelicci, F. Chiaradonna, S. Boehrer, 2002, Cancer research.

Negative regulation of IL-1beta production at the level of transcription in macrophages stimulated with LPS.

M. Fenton, T. Beissert, K. Nixdorff, 2001, Cytokine.

Efficient Reprogramming of Human Fibroblasts and Blood-Derived Endothelial Progenitor Cells Using Nonmodified RNA for Reprogramming and Immune Evasion.

Johanna E. Goldmann, Ö. Türeci, U. Şahin, 2015, Human gene therapy.

Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3' UTRs Identified by Cellular Library Screening.

Ö. Türeci, U. Şahin, M. Diken, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Monitoring Translation Activity of mRNA-Loaded Nanoparticles in Mice.

D. Schuppan, U. Şahin, M. Diken, 2018, Molecular pharmaceutics.

Antigen-specific oncolytic MV-based tumor vaccines through presentation of selected tumor-associated antigens on infected cells or virus-like particles

U. Şahin, K. Boller, Stephanie Erbar, 2017, Scientific Reports.

BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility

S. Güller, M. Ruthardt, T. Beissert, 2006, BMC Cancer.

Antigen-specific oncolytic MV-based tumor vaccines through presentation of selected tumor-associated antigens on infected cells or virus-like particles

U. Şahin, K. Boller, Stephanie Erbar, 2017, Scientific Reports.

A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform

H. Eldin, U. Şahin, K. Cichutek, 2015, Journal of Virology.

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation

Ö. Türeci, U. Şahin, C. Paret, 2020, Oncotarget.

An mRNA-encoded, long-lasting Interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

Ö. Türeci, U. Şahin, M. Diken, 2023, bioRxiv.

A taRNA vaccine candidate induces a specific immune response that protects mice against Chikungunya virus infections

U. Şahin, B. Schnierle, Mario Perković, 2022, Molecular therapy. Nucleic acids.

A trans-amplifying RNA simplified to essential elements is highly replicative and robustly immunogenic in mice.

U. Şahin, S. Brill, Mario Perković, 2023, Molecular Therapy.

Trans-amplifying RNA expressing functional miRNA mediates target gene suppression and simultaneous transgene expression

Martin Suchan, T. Beissert, Aline Beicht, 2024, Molecular therapy. Nucleic acids.

Trans-Amplifying RNA: A Journey from Alphavirus Research to Future Vaccines

T. Beissert, Ayşegül Yıldız, Cristian Răileanu, 2024, Viruses.

Targeting of the N‐terminal coiled coil oligomerization interface by a helix‐2 peptide inhibits unmutated and imatinib‐resistant BCR/ABL

C. Nervi, M. Ruthardt, T. Beissert, 2008, International journal of cancer.

Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571.

S. Boehrer, A. Bianchini, C. Nervi, 2003, Blood.

Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers.

Ö. Türeci, U. Şahin, M. Diken, 2024, Cancer cell.