B. Williams

发表

siRNA‐induced immunostimulation through TLR7 promotes antitumoral activity against HPV‐driven tumors in vivo

M. Behlke, S. Wu, N. McMillan, 2012, Immunology and cell biology.

RNase L and Double-Stranded RNA-Dependent Protein Kinase Exert Complementary Roles in Islet Cell Defense during Coxsackievirus Infection1

Monica Hultcrantz, Robert Silverman, R. Silverman, 2005, The Journal of Immunology.

DRBP76, a Double-stranded RNA-binding Nuclear Protein, Is Phosphorylated by the Interferon-induced Protein Kinase, PKR*

W. Guo, G. Sen, Rekha C. Patel, 1999, The Journal of Biological Chemistry.

NF-kB Activation by Double-Stranded-RNA-Activated Protein Kinase (PKR) Is Mediated through NF-kB-Inducing Kinase and IkB Kinase

T. Mogensen, M. Zamanian-Daryoush, J. DiDonato, 2000 .

This information is current as during Coxsackievirus Infection Complementary Roles in Islet Cell Defense RNA-Dependent Protein Kinase Exert RNase L and Double-Stranded Williams

R. Silverman, N. Sarvetnick, M. Hultcrantz, 2005 .

Protein kinase PKR is required for platelet‐derived growth factor signaling of c‐fos gene expression via Erks and Stat3

S. Kadereit, Zan Xu, M. Zamanian-Daryoush, 2001, The EMBO journal.

Central Role of Double-Stranded RNA-Activated Protein Kinase in Microbial Induction of Nitric Oxide Synthase1

C. A. de la Motte, S. Erzurum, S. Der, 2000, The Journal of Immunology.

OAS/PKR Pathways and α/β TCR+ T Cells are Required for Ad: IFN- γ Inhibition of HSV-1 in Cornea1

B. A. Austin, W. Halford, D. Carr, 2008 .

Identification of Critical Residues Required for Suppressor of Cytokine Signaling-specific Regulation of Interleukin-4 Signaling*

S. Haque, B. Williams, Phyllis C. Harbor, 2000, The Journal of Biological Chemistry.

Negative Regulation of CD8+ T Cell Function by the IFN-Induced and Double-Stranded RNA-Activated Kinase PKR1

R. Fairchild, S. Kadereit, Hui Xu, 2000, The Journal of Immunology.

Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase.

A. Aguzzi, Aseem Kumar, L. Reis, 1995, The EMBO journal.

A dynamically tuned double‐stranded RNA binding mechanism for the activation of antiviral kinase PKR

S. Nanduri, B. Williams, J. Qin, 2000, The EMBO journal.

Characterization of the Solution Complex between the Interferon-induced, Double-stranded RNA-activated Protein Kinase and HIV-I Trans-activating Region RNA*

B. Carpick, V. Graziano, X. Lee, 1997, The Journal of Biological Chemistry.

RNA-Dependent Protein Kinase PKR Is Required for Activation of NF-κB by IFN-γ in a STAT1-Independent Pathway1

R. Silverman, S. Haque, T. Mogensen, 2001, The Journal of Immunology.

Structure of the double‐stranded RNA‐binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA‐mediated activation

B. Williams, S. Nanduri, B. Carpick, 1998, The EMBO journal.

Regulation of WT1 by phosphorylation: inhibition of DNA binding, alteration of transcriptional activity and cellular translocation.

A. Gurney, C. Campbell, B. Raychaudhuri, 1996, The EMBO journal.

Subcellular localization of the von Hippel‐Lindau disease gene product is cell cycle‐dependent

B. Zbar, T. Stackhouse, I. Kuzmin, 1998, International journal of cancer.

The lack of RNA‐dependent protein kinase enhances susceptibility of mice to genital herpes simplex virus type 2 infection

B. Williams, R. Silverman, D. Carr, 2006, Immunology.

The protein kinase R modifies gut physiology to limit colitis

R. Silverman, C. A. de la Motte, A. Chakrabarti, 2023, Frontiers in Immunology.

Double‐stranded RNA‐dependent protein kinase (PKR) is downregulated by phorbol ester

Yan Zhou, M. Whitmore, Aimin Zhou, 2005, The FEBS journal.

Activation of p38 Mitogen-Activated Protein Kinase and c-Jun NH2-Terminal Kinase by Double-Stranded RNA and Encephalomyocarditis Virus: Involvement of RNase L, Protein Kinase R, and Alternative Pathways

Robert H. Silverman, R. Silverman, M. Iordanov, 2000, Molecular and Cellular Biology.

Mutations in the Double-stranded RNA-activated Protein Kinase Insert Region That Uncouple Catalysis from eIF2α Binding*

B. Williams, Ruorong Cai, 1998, The Journal of Biological Chemistry.

The interferon-induced double-stranded RNA-activated human p68 protein kinase potently inhibits protein synthesis in cultured cells.

M. Esteban, A. Hovanessian, B. Williams, 1993, Virology.

Induction of E-Selectin Expression by Double-Stranded RNA and TNF-α Is Attenuated in Murine Aortic Endothelial Cells Derived from Double-Stranded RNA-Activated Kinase (PKR)-Null Mice1

C. A. de la Motte, S. Bandyopadhyay, B. Williams, 2000, The Journal of Immunology.

The DNA-binding subunit p140 of replication factor C is upregulated in cycling cells and associates with G1 phase cell cycle regulatory proteins

B. Williams, S. Haque, C. Huber, 1999, Journal of Molecular Medicine.

Interferon‐alpha‐induced phosphorylation and activation of cytosolic phospholipase A2 is required for the formation of interferon‐stimulated gene factor three.

S. Haque, V. Flati, B. Williams, 1996, The EMBO journal.

1H, 13C, 15N Resonance Assignment of the 20 kDa Double Stranded RNA Binding Domain of PKR

S. Nanduri, B. Carpick, B. Williams, 1998, Journal of biomolecular NMR.

Loss of heterozygosity at chromosome 11p15 in Wilms tumors: identification of two independent regions

B. Williams, Ping Chen, H. Yeger, 1998, Oncogene.

How cells respond to interferons.

G. Stark, I. Kerr, B. Williams, 1998, Annual review of biochemistry.

TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophages

M. J. Cody, B. Williams, J. Major, 2002, Nature Immunology.

JNK2 and IKKbeta are required for activating the innate response to viral infection.

M. Karin, Lufen Chang, Zhi-wei Li, 1999, Immunity.

Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth

M. Katze, B. Williams, G. Barber, 1992, Journal of Virology.

RNA interference and double-stranded-RNA-activated pathways.

B. Williams, Carol A. Sledz, C. A. Sledz, 2004, Biochemical Society transactions.

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis.

S. Der, B. Williams, C. Weissmann, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Apoptosis and interferons: Role of interferon-stimulated genes as mediators of apoptosis

B. Williams, R. Silverman, E. Borden, 2003, Apoptosis.

HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes.

B. Williams, R. Silverman, G. Sen, 1994, Virology.

Impaired innate host defense causes susceptibility to respiratory virus infections in cystic fibrosis.

B. Williams, S. Erzurum, S. Comhair, 2003, Immunity.

Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1.

G. Stark, I. Kerr, S. Haque, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Expression of intracellular interferon constitutively activates ISGF3 and confers resistance to EMC viral infection.

B. Coulombe, B. Williams, Aseem Kumar, 1996, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Transcriptional regulation of interferon-stimulated genes.

B. Williams, B. Williams, 1991, European journal of biochemistry.

Mutational Analysis of the Double-stranded RNA (dsRNA) Binding Domain of the dsRNA-activated Protein Kinase, PKR (*)

W. Toone, B. Carpick, N. McMillan, 1995, The Journal of Biological Chemistry.

Structure and function of the protein kinase R.

B. Williams, B. Williams, A. Sadler, 2007, Current topics in microbiology and immunology.

Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation.

B. Williams, B R Williams, B. Williams, 1997, Biochemical Society transactions.

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

Aseem Kumar, A. Kumar, J. Hiscott, 1994, Proceedings of the National Academy of Sciences of the United States of America.

HIV-I TAT inhibits PKR activity by both RNA-dependent and RNA-independent mechanisms.

B. Williams, B. Carpick, K. Jeang, 2000, Archives of biochemistry and biophysics.

Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

B. Williams, R. Silverman, S. Der, 1999, Virology.

Effect of deficiency of the double-stranded RNA-dependent protein kinase, PKR, on antiviral resistance in the presence or absence of ribonuclease L: HSV-1 replication is particularly sensitive to deficiency of the major IFN-mediated enzymes.

B. Williams, R. Silverman, M. Al-Ahdal, 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

P53, bcl-2, and Bax expression in renal cell carcinoma.

B. Williams, A. Novick, B. Williams, 1998, Urology.

Interferon g and Interleukin 4 Stimulate Prolonged Expression of Inducible Nitric Oxide Synthase in Human Airway Epithelium through Synthesis of Soluble Mediators

B. Williams, R. Dweik, S. Erzurum, 1997 .

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

M. Katze, B. Williams, G. Barber, 1991, Molecular and cellular biology.

Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase.

G. Feng, Aseem Kumar, A. Kumar, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators.

R. Dweik, S. Erzurum, W. Calhoun, 1997, The Journal of clinical investigation.