Emmanuelle Braud

发表

Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups

C. Atdjian, Dylan Coelho, L. Iannazzo, 2020, Molecules.

Insights into the interaction of high potency inhibitor IRC‐083864 with phosphatase CDC25

M. Sari, M. Miteva, G. Bertho, 2017, Proteins.

Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: effect of dimerisation on phosphatase inhibition.

B. Villoutreix, M. Miteva, C. Garbay, 2012, Bioorganic & medicinal chemistry letters.

Study of the docking-dependent PLK1 phosphorylation of the CDC25B phosphatase.

C. Froment, O. Burlet-Schiltz, B. Ducommun, 2011, Biochemical and biophysical research communications.

Preparation and evaluation of a set of bis(methoxycarbonylmethylthio) heteroquinones as CDC25B phosphatase inhibitors

T. Besset, C. Garbay, C. Morin, 2011 .

Development of Novel Thiazolopyrimidines as CDC25B Phosphatase Inhibitors

B. Villoutreix, B. Ducommun, O. Mondésert, 2009, ChemMedChem.

Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites

L. Droogmans, C. Tisné, F. Brachet, 2019, RNA biology.

Synthesis of tRNA analogues containing a terminal ribose locked in the South conformation to study tRNA-dependent enzymes.

M. Arthur, L. Iannazzo, M. Ethève-Quelquejeu, 2018, Organic & biomolecular chemistry.

Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of L,D-Transpeptidase LdtMt1 of Mycobacterium tuberculosis and the Stability toward Hydrolysis by β-Lactamase BlaC.

J. Mainardi, M. Arthur, F. Compain, 2016, Journal of medicinal chemistry.

Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties.

N. Gresh, B. Ducommun, O. Mondésert, 2008, Bioorganic & medicinal chemistry.

Rapid discovery of triazolobenzylidene-thiazolopyrimidines (TBTP) as CDC25 phosphatase inhibitors by parallel click chemistry and in situ screening.

C. Garbay, Emmanuelle Braud, S. Kolb, 2009, Journal of combinatorial chemistry.

Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes.

T. Brown, D. Mengin-Lecreulx, M. Arthur, 2016, Angewandte Chemie.

Synthesis of 3′‐Fluoro‐tRNA Analogues for Exploring Non‐ribosomal Peptide Synthesis in Bacteria

J. Herbeuval, M. Arthur, L. Iannazzo, 2015, Chembiochem : a European journal of chemical biology.

Synthesis of SAM-Adenosine Conjugates for the Study of m6 A-RNA Methyltransferases

C. Atdjian, L. Iannazzo, M. Ethève-Quelquejeu, 2018, European Journal of Organic Chemistry.

Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity.

M. Montès, N. Gresh, M. Miteva, 2005, Bioorganic & medicinal chemistry.

Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase

C. Tisné, C. Atdjian, L. Iannazzo, 2022, Nucleic acids research.

Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d-Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis.

D. Schnappinger, D. Mengin-Lecreulx, M. Arthur, 2018, Chemistry.

5-Substituted [1]pyrindine derivatives with antiproliferative activity.

B. Ducommun, O. Mondésert, C. Garbay, 2010, European journal of medicinal chemistry.

Receptor-Based Virtual Ligand Screening for the Identification of Novel CDC25 Phosphatase Inhibitors

Bruno O. Villoutreix, Maria A. Miteva, Matthieu Montes, 2008, J. Chem. Inf. Model..

Synthesis and combinatorial approach of the reactivity of 6- and 7-arylthieno[3,2-d][1,3]oxazine-2,4-diones

S. Rault, J. Lancelot, Emmanuelle Braud, 2003 .

Solution-phase parallel synthesis of a 1140-member ureidothiophene carboxylic acid library.

S. Rault, J. Lancelot, Emmanuelle Braud, 2005, Journal of combinatorial chemistry.

Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis

L. Mayer, J. Mainardi, M. Arthur, 2022, Antimicrobial agents and chemotherapy.

Click and Release Chemistry for Activity-based Purification of b-lactam targets.

M. Arthur, F. Taran, F. Rusconi, 2021, Chemistry.

Synthesis of Multifunctionalized 2-Iminothiazolidin-4-ones and Their 2-Arylimino Derivatives

L. Le Corre, C. Garbay, C. Gravier-Pelletier, 2016, Synthesis.

The catalytic mechanism of the RNA methyltransferase METTL3

A. Caflisch, Dylan Coelho, L. Iannazzo, 2023, bioRxiv.

Synthesis and biological evaluation of non-isomerizable analogues of Ala-tRNA(Ala).

M. Arthur, L. Iannazzo, M. Ethève-Quelquejeu, 2013, Organic & biomolecular chemistry.

The catalytic mechanism of the RNA methyltransferase METTL3

A. Caflisch, Danzhi Huang, Dylan Coelho, 2024, eLife.

The catalytic mechanism of the RNA methyltransferase METTL3

A. Caflisch, Danzhi Huang, Dylan Coelho, 2023, bioRxiv.