Anne H. Shen

Therapeutic base editing of human hematopoietic stem cells

Chunyan Ren, Luca Pinello, J. Keith Joung, 2020, Nature Medicine.

Therapeutic base editing of human hematopoietic stem cells

Jason M. Gehrke, J. Joung, J. Manis, 2019, Nature Medicine.

BCL11A enhancer edited hematopoietic stem cells persist in rhesus monkeys without toxicity.

Shondra M. Pruett-Miller, S. Tsai, S. Wolfe, 2020, The Journal of clinical investigation.

Highly efficient therapeutic gene editing of human hematopoietic stem cells

Chunyan Ren, Luca Pinello, Luca Biasco, 2019, Nature Medicine.

Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia.

Luca Pinello, Kevin Luk, Scot A Wolfe, 2019, Blood.

Dissecting ELANE neutropenia pathogenicity by human HSC gene editing.

P. Newburger, S. Wolfe, D. E. Bauer, 2021, Cell stem cell.

Highly efficient therapeutic gene editing of human hematopoietic stem cells

David A. Williams, Mitchel A. Cole, Benjamin P. Roscoe, 2019, Nature Medicine.