T. Furihata

H. Tsutsui, S. Matsushima, S. Kinugawa, 2015, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients

F. Dela, T. Nakajima, T. Anzai, 2019, Scientific Reports.

of the skeletal muscle in type 2 diabetic mice exercise capacity and impaired mitochondrial function Angiotensin II receptor blocker improves the lowered

H. Tsutsui, S. Matsushima, Wataru Mizushima, 2013 .

Deletion of NAD(P)H Oxidase 2 Prevents Angiotensin II-Induced Skeletal Muscle Atrophy

Wataru Mizushima, S. Kinugawa, K. Okita, 2018, BioMed research international.

The disruption of invariant natural killer T cells exacerbates cardiac hypertrophy and failure caused by pressure overload in mice

H. Tsutsui, K. Iwabuchi, S. Kinugawa, 2020, Experimental physiology.

Brain-Derived Neurotrophic Factor Improves Limited Exercise Capacity in Mice With Heart Failure.

K. Nakayama, M. Matsumoto, S. Hatakeyama, 2018, Circulation.

Decreased serum brain-derived neurotrophic factor levels are correlated with exercise intolerance in patients with heart failure.

K. Oba, H. Tsutsui, S. Matsushima, 2013, International journal of cardiology.

Pioglitazone ameliorates the lowered exercise capacity and impaired mitochondrial 1 function of the skeletal muscle in type 2 diabetic mice 2 Running title : Exercise capacity and insulin resistance 3 4

H. Tsutsui, Wataru Mizushima, S. Kinugawa, 2018 .

Pioglitazone ameliorates the lowered exercise capacity and impaired mitochondrial function of the skeletal muscle in type 2 diabetic mice.

H. Tsutsui, S. Matsushima, Wataru Mizushima, 2014, European journal of pharmacology.

Inhibition of xanthine oxidase in the acute phase of myocardial infarction prevents skeletal muscle abnormalities and exercise intolerance.

T. Nakajima, H. Sabe, T. Anzai, 2020, Cardiovascular research.

Diffuse large B-cell lymphoma diagnosed by intracardiac echocardiography-guided cardiac tumor biopsy.

H. Tsutsui, S. Yamada, K. Kubota, 2012, Internal medicine.

Activation of invariant natural killer T cells by α-galactosylceramide ameliorates myocardial ischemia/reperfusion injury in mice.

M. Taniguchi, T. Nakayama, H. Tsutsui, 2013, Journal of molecular and cellular cardiology.

Mitochondrial respiration of complex II is not lower than that of complex I in mouse skeletal muscle

S. Kinugawa, S. Takada, T. Furihata, 2019, Biochemistry and biophysics reports.

Increased plasma soluble (pro)renin receptor levels are correlated with renal dysfunction in patients with heart failure.

H. Tsutsui, S. Matsushima, S. Kinugawa, 2013, International journal of cardiology.

Combination of exercise training and diet restriction normalizes limited exercise capacity and impaired skeletal muscle function in diet-induced diabetic mice.

H. Tsutsui, S. Kinugawa, K. Okita, 2014, Endocrinology.

Tyrosine kinase inhibitors induce mitochondrial dysfunction during cardiomyocyte differentiation through alteration of GATA4-mediated networks

L. Steinmetz, W. Wong, M. Snyder, 2020, bioRxiv.

The novel heart-specific RING finger protein 207 is involved in energy metabolism in cardiomyocytes.

K. Nakayama, M. Matsumoto, S. Yanagi, 2016, Journal of molecular and cellular cardiology.

(Pro)renin receptor in skeletal muscle is involved in the development of insulin resistance associated with postinfarct heart failure in mice.

H. Tsutsui, S. Kinugawa, K. Okita, 2014, American journal of physiology. Endocrinology and metabolism.

Brain-Derived Neurotrophic Factor Improves Impaired Fatty Acid Oxidation Via the Activation of Adenosine Monophosphate-activated Protein Kinase-α - Proliferator-Activated Receptor-r Coactivator-1α Signaling in Skeletal Muscle of Mice With Heart Failure.

H. Sabe, Wataru Mizushima, S. Kinugawa, 2020, Circulation. Heart failure.

Serum Brain-Derived Neurotrophic Factor Level Predicts Adverse 1 Clinical Outcomes in Patients with Heart Failure

K. Oba, H. Tsutsui, S. Kinugawa, 2017 .

Impact of High Respiratory Exchange Ratio During Submaximal Exercise on Adverse Clinical Outcome in Heart Failure.

T. Anzai, S. Kinugawa, K. Okita, 2018, Circulation journal : official journal of the Japanese Circulation Society.

Serum Brain-Derived Neurotrophic Factor Level Predicts Adverse 1 Clinical Outcomes in Patients with Heart Failure

K. Oba, H. Tsutsui, S. Kinugawa, 2017 .

Serum myostatin levels are independently associated with skeletal muscle wasting in patients with heart failure.

K. Oba, H. Tsutsui, S. Kinugawa, 2016, International journal of cardiology.

Clinical Impact and Associated Factors of Delayed Ambulation in Patients With Acute Heart Failure

T. Anzai, S. Kinugawa, S. Takada, 2019, Circulation reports.

Enhanced mitochondrial oxidative metabolism in peripheral blood mononuclear cells is associated with fatty liver in obese young adults

H. Sabe, I. Yokota, S. Hashino, 2023, Scientific Reports.

Angiotensin II can directly induce mitochondrial dysfunction, decrease oxidative fibre number and induce atrophy in mouse hindlimb skeletal muscle

H. Tsutsui, Wataru Mizushima, S. Kinugawa, 2015, Experimental physiology.

Angiotensin‐converting enzyme inhibitor prevents skeletal muscle fibrosis in diabetic mice

S. Kinugawa, S. Takada, T. Furihata, 2021, Experimental physiology.

A mitochondrial delivery system using liposome-based nanocarriers that target myoblast cells.

T. Anzai, H. Harashima, Yuma Yamada, 2019, Mitochondrion.

Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure

K. Ueda, D. Kang, H. Sabe, 2021, Proceedings of the National Academy of Sciences of the United States of America.

Linoleic acid improves assembly of the CII subunit and CIII2/CIV complex of the mitochondrial oxidative phosphorylation system in heart failure

D. Kang, H. Sabe, Daiki Setoyama, 2019, Cell Communication and Signaling.

Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure

H. Sabe, J. Nio-Kobayashi, H. Tsutsui, 2021, Communications Biology.

Angiotensin-converting-enzyme inhibitor prevents skeletal muscle fibrosis in myocardial infarction mice

S. Kinugawa, S. Takada, J. Matsumoto, 2020, Skeletal Muscle.

Serum brain-derived neurotropic factor level predicts adverse clinical outcomes in patients with heart failure.

K. Oba, H. Tsutsui, S. Kinugawa, 2014, Journal of cardiac failure.

AST-120 ameliorates lowered exercise capacity and mitochondrial biogenesis in the skeletal muscle from mice with chronic kidney disease via reducing oxidative stress.

H. Tsutsui, S. Kinugawa, S. Takada, 2015, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

The novel heart-specific RING finger protein 207 is involved in energy metabolism in cardiomyocytes.

K. Nakayama, M. Matsumoto, S. Yanagi, 2016, Journal of molecular and cellular cardiology.

Direct renin inhibitor ameliorates insulin resistance by improving insulin signaling and oxidative stress in the skeletal muscle from post-infarct heart failure in mice.

H. Tsutsui, Wataru Mizushima, S. Kinugawa, 2016, European journal of pharmacology.