D. Schaafsma

发表

Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches.

M. Czubryt, I. Dixon, M. Akbari, 2018, Comprehensive Physiology.

Therapeutic potential of targeting regulatory mechanisms of hepatic stellate cell activation in liver fibrosis.

S. Ghavami, D. Schaafsma, K. Baghaei, 2021, Drug discovery today.

Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem.

R. Panettieri, O. Tliba, Y. Amrani, 2020, Pharmacology & therapeutics.

Insulin-induced laminin expression promotes a hypercontractile airway smooth muscle phenotype.

T. Tran, H. Meurs, J. Zaagsma, 2009, American journal of respiratory cell and molecular biology.

Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype.

R. Gosens, H. Meurs, J. Zaagsma, 2004, European journal of pharmacology.

Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison

A. Halayko, R. Gosens, H. Meurs, 2007, European Respiratory Journal.

Rho kinase inhibitors: a novel therapeutical intervention in asthma?

A. Halayko, R. Gosens, H. Meurs, 2008, European journal of pharmacology.

Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle.

S. Ghavami, A. Halayko, B. Yeganeh, 2012, American journal of physiology. Lung cellular and molecular physiology.

Regulation of GPCR-mediated smooth muscle contraction: implications for asthma and pulmonary hypertension.

J. Ward, D. Schaafsma, O. Ojo, 2013, Pulmonary pharmacology & therapeutics.

The mevalonate cascade as a target to suppress extracellular matrix synthesis by human airway smooth muscle.

G. Hatch, S. Ghavami, A. Halayko, 2011, American journal of respiratory cell and molecular biology.

Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53

S. Ghavami, M. Los, A. Halayko, 2011, PloS one.

Insulin increases the expression of contractile phenotypic markers in airway smooth muscle.

A. Halayko, H. Baarsma, G. Stelmack, 2007, American journal of physiology. Cell physiology.

Insulin induces airway smooth muscle contraction

R. Gosens, H. Meurs, J. Zaagsma, 2007, British journal of pharmacology.

RESEARCH PAPER Insulin induces airway smooth muscle contraction

R. Gosens, H. Meurs, J. Zaagsma, 2007 .

Inhibition of Rho-kinase normalizes nonspecific hyperresponsiveness in passively sensitized airway smooth muscle preparations.

H. Meurs, J. Zaagsma, D. Schaafsma, 2006, European journal of pharmacology.

Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction

H. Meurs, J. Zaagsma, D. Schaafsma, 2006, Respiratory research.

Rationale for Effective Prophylaxis Against COVID‐19 Through Simultaneous Blockade of Both Endosomal and Non‐Endosomal SARS‐CoV‐2 Entry into Host Cell

M. Banach, I. Berindan‐Neagoe, S. Ghavami, 2021, Clinical and Translational Science.

Lessons from SARS and MERS remind us of the possible therapeutic effects of implementing a siRNA strategy to target COVID‐19: Shoot the messenger!

M. Banach, I. Berindan‐Neagoe, S. Ghavami, 2020, Journal of cellular and molecular medicine.

Pharmacology of airway smooth muscle proliferation.

S. Roscioni, R. Gosens, Martina Schmidt, 2008, European journal of pharmacology.

Airway smooth muscle in asthma: phenotype plasticity and function.

T. Tran, D. Schaafsma, J. Hirota, 2009, Pulmonary pharmacology & therapeutics.

Extracellular matrix proteins differentially regulate airway smooth muscle phenotype and function.

H. Meurs, J. Zaagsma, D. Schaafsma, 2007, American journal of physiology. Lung cellular and molecular physiology.

The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation.

H. Meurs, J. Zaagsma, D. Schaafsma, 2008, American journal of physiology. Lung cellular and molecular physiology.

Central role of Rho-kinase in the pathophysiology of allergic asthma

D. Schaafsma, 2007 .

Allergic sensitization enhances the contribution of Rho‐kinase to airway smooth muscle contraction

R. Gosens, H. Meurs, J. Zaagsma, 2004, British journal of pharmacology.

Muscarinic M3 receptor‐dependent regulation of airway smooth muscle contractile phenotype

R. Gosens, H. Meurs, J. Zaagsma, 2004, British journal of pharmacology.

Growth factor-induced contraction of human bronchial smooth muscle is Rho-kinase-dependent.

R. Gosens, H. Meurs, J. Zaagsma, 2004, European journal of pharmacology.

Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction

R. Gosens, H. Meurs, J. Zaagsma, 2005, Respiratory research.

Differential Rho‐kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction

H. Meurs, J. Zaagsma, D. Schaafsma, 2006, British journal of pharmacology.

The role of osteoprotegerin (OPG) in fibrosis: Its potential as a biomarker and/or biological target for the treatment of fibrotic diseases.

B. Melgert, A. Adhyatmika, D. Schaafsma, 2021, Pharmacology & therapeutics.

Pleiotropic effects of statins: a focus on cancer.

Marek J. Łos, S. Ghavami, T. Madrakian, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Non-genomic Effects of Glucocorticoids: An Updated View.

Reynold A Panettieri, R. Ostrom, R. Panettieri, 2019, Trends in pharmacological sciences.

Motility, survival, and proliferation.

S. Ghavami, A. Halayko, W. Gerthoffer, 2012, Comprehensive Physiology.

Control of the Mesenchymal-Derived Cell Phenotype by Ski and Meox2: A Putative Mechanism for Postdevelopmental Phenoconversion

I. Dixon, A. Halayko, J. Wigle, 2011 .

Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts

S. Ghavami, A. Halayko, M. Laviolette, 2011, Respiratory research.

Magnetic Nanomaterials in Microfluidic Sensors for Virus Detection: A Review

S. Ghavami, P. Mokarram, M. Los, 2021 .

Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c.

G. Hatch, S. Ghavami, M. Los, 2010, Biochimica et biophysica acta.

' s personal copy Statin-triggered cell death in primary human lung mesenchymal cells involves p 53-PUMA and release of Smac and Omi but not cytochrome c

G. Hatch, S. Ghavami, M. Los, 2010 .

Monomeric G-proteins as signal transducers in airway physiology and pathophysiology.

S. Roscioni, Martina Schmidt, H. Meurs, 2008, Cellular signalling.

Rho-kinase as a drug target for the treatment of airway hyperrespon-siveness in asthma.

A. Halayko, R. Gosens, D. Schaafsma, 2006, Mini reviews in medicinal chemistry.

Rho-kinase as a drug target for the treatment of airway hyperresponsiveness in allergic asthma

A. Halayko, R. Gosens, D. Schaafsma, 2007 .

Caveolin-1 is required for contractile phenotype expression by airway smooth muscle cells

A. Halayko, W. Gerthoffer, G. Stelmack, 2011, Journal of cellular and molecular medicine.

Contribution of Rho-kinase (ROCK) to airway smooth muscle (ASM) contraction after allergic sensitization

R. Gosens, H. Meurs, J. Zaagsma, 2005 .

Heterologous amplification of homologous beta-adrenoceptor desensitization in airway smooth muscle

H. Meurs, J. Zaagsma, D. Schaafsma, 2006 .

Regulation of GPCR-mediated smooth muscle contraction: implications for asthma and pulmonary hypertension.

D. Schaafsma, O. Ojo, N. Irechukwu, 2013, Pulmonary pharmacology & therapeutics.

Growth factor-induced contraction of human bronchial smooth muscle is Rho-kinase-dependent.

R. Gosens, H. Meurs, J. Zaagsma, 2004, European journal of pharmacology.

Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction

H. Meurs, J. Zaagsma, D. Schaafsma, 2006, Respiratory research.