A. Noble

发表

Effect of Transforming Growth Factor-β Receptor I Kinase Inhibitor 2,4-Disubstituted Pteridine (SD-208) in Chronic Allergic Airway Inflammation and Remodeling

K. Chung, A. Niimi, T. Oates, 2006, Journal of Pharmacology and Experimental Therapeutics.

FGF10 is an essential regulator of tracheal submucosal gland morphogenesis.

T. Teshima, A. Tucker, A. Noble, 2019, Developmental biology.

Importance of p38 mitogen-activated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness.

K. Chung, Sum-Yee Leung, S. Medicherla, 2006, European journal of pharmacology.

CD8(+) T cell subsets and chronic obstructive pulmonary disease.

B. O'connor, D. Kemeny, L. Loh, 1999, American journal of respiratory and critical care medicine.

Combined Triggering of Dendritic Cell Receptors Results in Synergistic Activation and Potent Cytotoxic Immunity1

F. Farzaneh, C. Cowled, J. Wells, 2008, The Journal of Immunology.

FGF and EDA pathways control initiation and branching of distinct subsets of developing nasal glands

D. Rice, D. Headon, A. Tucker, 2016, Developmental biology.

Early Th1 / Th2 cell polarization in the absence of IL‐4 and IL‐12: T cell receptor signaling regulates the response to cytokines in CD4 and CD8 T cells

D. Kemeny, A. Noble, M. Thomas, 2001, European journal of immunology.

Altered immunity to microbiota, B cell activation and depleted γδ/resident memory T cells in colorectal cancer

L. Durant, S. James, S. Carding, 2021, Cancer Immunology, Immunotherapy.

Molecular signals and genetic reprogramming in peripheral T‐cell differentiation

A. Noble, Alistair Noble, 2000 .

Blockade of chronic graft‐versus‐host disease by alloantigen‐induced CD4+CD25+Foxp3+ regulatory T cells in nonlymphopenic hosts

A. Noble, A. Giorgini, 2007, Journal of leukocyte biology.

Suppression of airway inflammation by a natural acute infection of the intestinal epithelium

A. Hayday, A. Smith, D. Gibbons, 2009, Mucosal Immunology.

Alloantigen‐specific regulatory T cells prevent experimental chronic graft‐versus‐host disease by simultaneous control of allo‐ and autoreactivity

R. Lechler, P. Sagoo, G. Lombardi, 2012, European journal of immunology.

Cytokine-induced IL-10-secreting CD8 T cells represent a phenotypically distinct suppressor T-cell lineage.

A. Noble, A. Giorgini, Jamie A. Leggat, 2006, Blood.

Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

A. Hart, L. Durant, J. Brooks, 2019, Microbiome.

Role of Nitric Oxide in Chronic Allergen-Induced Airway Cell Proliferation and Inflammation

K. Chung, D. Groneberg, M. Salmon, 2003, Journal of Pharmacology and Experimental Therapeutics.

The role of CD8+ T cells in immunoglobulin E regulation

D. Kemeny, D. Díaz-Sánchez, A. Noble, 1995, Allergy.

Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling

C. Lloyd, A. Noble, J. Zhao, 2012, Mucosal Immunology.

Complete inhibition of allergic airway inflammation and remodelling in quadruple IL‐4/5/9/13−/− mice

K. Chung, A. McKenzie, A. Noble, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization.

A. Hayday, D. Gibbons, Adrian L. Smith, 2008, The Journal of allergy and clinical immunology.

Effect of an inhibitor of Jun N‐terminal protein kinase, SP600125, in single allergen challenge in sensitized rats

I. Adcock, K. Chung, D. Groneberg, 2004, Immunology.

Tc2 cells respond to soluble antigen in the respiratory tract and induce lung eosinophilia and bronchial hyperresponsiveness

D. Kemeny, C. Walker, A. Noble, 2004, European journal of immunology.

IFN-gamma and IL-4 regulate the growth and differentiation of CD8+ T cells into subpopulations with distinct cytokine profiles.

P. MacAry, D. Kemeny, A. Noble, 1995, Journal of immunology.

Elimination of IgE regulatory rat CD8+ T cells in vivo increases the co-ordinate expression of Th2 cytokines IL-4, IL-5 and IL-10.

T. Lee, D. Kemeny, D. Díaz-Sánchez, 1993, Immunology.

Generation of rat Th2-like cells in vitro is interleukin-4-dependent and inhibited by interferon-gamma.

D. Kemeny, A. Noble, D. Staynov, 1993, Immunology.

Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine

J. Wells, C. Lloyd, A. Noble, 2009, Mucosal Immunology.

Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration.

D. Kemeny, C. Cowled, J. Wells, 2007, The Journal of allergy and clinical immunology.

Activation‐induced cell death of human T‐cell subsets is mediated by Fas and granzyme B but is independent of TNF‐α

D. Kemeny, A. Noble, P. Gorak‐Stolinska, 2001, Journal of leukocyte biology.

The Balance of Protein Kinase C and Calcium Signaling Directs T Cell Subset Development1

A. Noble, B. Vyas, M. Vukmanovic‐Stejic, 2000, The Journal of Immunology.

DevelopmentCalcium Signaling Directs T Cell Subset The Balance of Protein Kinase C and

D. Kemeny, A. Noble, B. Vyas, 2000 .

Specificity, restriction and effector mechanisms of immunoregulatory CD8 T cells

D. Kemeny, A. Noble, M. Vukmanovic‐Stejic, 2001, Immunology.

Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses.

H. Cantor, A. Noble, Z. S. Zhao, 1998, Journal of immunology.

Cytokine production by highly purified human CD8+ T cells.

D. Kemeny, D. Richards, A. Noble, 1995, International archives of allergy and immunology.

Immune regulation: a new role for the CD8+ T cell.

D. Kemeny, D. Díaz-Sánchez, A. Noble, 1994, Immunology today.

Antigen‐specific CD8+ T cells inhibit IgE responses and interleukin‐4 production by CD4+ T cells

P. MacAry, D. Kemeny, A. Noble, 1997, European journal of immunology.

An Essential Role for IL-18 in CD8 T Cell-Mediated Suppression of IgE Responses1

D. Kemeny, M. Salagianni, A. Noble, 2007, The Journal of Immunology.

CD8 T Cells Inhibit IgE Via Dendritic Cell IL-12 Induction That Promotes Th1 T Cell Counter-Regulation1

P. Askenase, D. Kemeny, A. Noble, 2002, The Journal of Immunology.

Interleukin-4 enhances interferon-gamma synthesis but inhibits development of interferon-gamma-producing cells.

D. Kemeny, A. Noble, 1995, Immunology.

Altered immunity to microbiota, B cell activation and depleted (cid:74)(cid:71) / resident memory T cells in colorectal cancer

L. Durant, S. Carding, L. Hoyles, 2021 .

Suppression of T Helper 2 Responses Cell II. Qa-1 on Activated B Cells Stimulates CD8 Suppression of Immune Responses by CD8 Cells.

H. Cantor, A. Noble, Zi-Shan Zhao, 2017 .

Qa-1 on Activated B Cells Stimulates CD 8 Suppression of Immune Responses by CD 8 Cells

H. Cantor, A. Noble, Zi-Shan Zhao, 1998 .

An essential role for IL-18 in CD8 T cell-mediated suppression of IgE responses

D. Kemeny, M. Salagianni, A. Noble, 2007, The Journal of Immunology.

CD8+ immunoregulatory cells in the graft‐versus‐host reaction: CD8 T cells activate dendritic cells to secrete interleukin‐12/interleukin‐18 and induce T helper 1 autoantibody

A. Noble, E. Inderberg, Jamie A. Leggat, 2003, Immunology.

Activation-induced cell death in human T cells is a suicidal process regulated by cell density but superantigen induces T cell fratricide.

D. Kemeny, A. Noble, P. Gorak‐Stolinska, 2002, Cellular immunology.

Elimination of IgE regulatory rat CD8+ T cells in vivo differentially modulates interleukin-4 and interferon-gamma but not interleukin-2 production by splenic T cells.

T. Lee, D. Kemeny, D. Díaz-Sánchez, 1993, Immunology.

The combined molecular adjuvant CASAC enhances the CD8+ T cell response to a tumor-associated self-antigen in aged, immunosenescent mice

F. Farzaneh, G. Tye, R. Quartey‐Papafio, 2015, Immunity & Ageing.

TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers

P. Morton, M. Parsons, G. Jenkins, 2016, Scientific Reports.

T Cytotoxic 1 and T Cytotoxic 2 CD8 T Cells Both Inhibit IgE Responses

P. MacAry, P. Askenase, D. Kemeny, 2001, International Archives of Allergy and Immunology.

Short-term culture of CD8 cells and intracellular cytokine staining.

A. Noble, B. Vyas, 2008, Methods in molecular medicine.

Do functional subsets of leukocytes arise by divergent or linear differentiation?

D. Kemeny, A. Noble, 2002, Immunology.

Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells.

H. Cantor, A. Noble, G. Pestano, 1998, Journal of immunology.

Antigen-Activated CD4 Cells Unidirectional Fas-Mediated Apoptosis of I. Superantigen-Activated CD8 Cells Induce Suppression of Immune Responses by CD8 Cells

H. Cantor, A. Noble, G. Pestano, 1998 .

Review article: molecular signals and genetic reprogramming in peripheral T-cell differentiation.

A. Noble, 2000, Immunology.

Dysbiosis in pre-cancerous mucosa may drive immune dysfunction: a study of immune system: microbiota interaction in familial adenomatous polyposis

L. Durant, S. Carding, L. Hoyles, 2021, medRxiv.

From Molecular Science to the Treatment of Allergy

M. Manns, Jane Wilkinson, P. Hufnagl, 1999, International Archives of Allergy and Immunology.

Gut Microbiome in BALB/c and C57BL/6J Mice Undergoing Experimental Thyroid Autoimmunity Associate with Differences in Immunological Responses and Thyroid Function

J. Marchesi, F. Biscarini, G. Masetti, 2018, Hormone and Metabolic Research.

Comparative Assessment of Female Mouse Model of Graves' Orbitopathy Under Different Environments, Accompanied by Proinflammatory Cytokine and T-Cell Responses to Thyrotropin Hormone Receptor Antigen.

B. Edelmann, W. Hansen, S. Moshkelgosha, 2016, Endocrinology.

Deficient Resident Memory T Cell and CD8 T Cell Response to Commensals in Inflammatory Bowel Disease

A. Hart, L. Durant, J. Segal, 2019, Journal of Crohn's & colitis.

COMMENSALS IN INFLAMMATORY BOWEL DISEASE

A. Hart, L. Durant, J. Segal, 2019 .

Human Tc1 and Tc2/Tc0 CD8 T-cell clones display distinct cell surface and functional phenotypes.

B Vyas, D. Kemeny, A. Noble, 2000, Blood.

Follicular helper T cells are responsible for IgE responses to Der p 1 following house dust mite sensitization in mice

A. Noble, J. Zhao, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Semi-allogeneic dendritic cells can induce antigen-specific T-cell activation, which is not enhanced by concurrent alloreactivity

F. Farzaneh, C. Cowled, J. Wells, 2007, Cancer Immunology, Immunotherapy.

Counter-Regulation IL-12 Induction That Promotes Th1 T Cell CD8 T Cells Inhibit IgE Via Dendritic Cell

Matthew J. Thomas, D. Kemeny, A. Noble, 2001 .

IL-12 Induction That Promotes Th 1 T Cell CD 8 T Cells Inhibit IgE Via Dendritic Cell

P. Askenase, D. Kemeny, A. Noble, 2001 .

The Origin of Plasma-Derived Bacterial Extracellular Vesicles in Healthy Individuals and Patients with Inflammatory Bowel Disease: A Pilot Study

G. Savva, S. Carding, R. Stentz, 2021, Genes.

Dishing the dirt on asthma: What we can learn from poor hygiene

C. D. de Lara, A. Noble, 2007, Biologics : targets & therapy.

IL‐12 and IL‐4 activate a CD39‐dependent intrinsic peripheral tolerance mechanism in CD8+ T cells

L. Fairbanks, A. Noble, A. Lovell, 2016, European journal of immunology.

Do we have memory of danger as well as antigen?

Alistair Noble, A. Noble, 2009, Trends in immunology.

IL–4 Inhibits Human CD8 T Cell Expression of the Common IL–2 Receptor Gamma Chain

D. Kemeny, A. Noble, B. Vyas, 1999, International Archives of Allergy and Immunology.

Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation.

A. Kelly, Wuding Zhou, S. Sacks, 2008, Blood.

The combined molecular adjuvant CASAC enhances the CD8+ T cell response to a tumor-associated self-antigen in aged, immunosenescent mice

F. Farzaneh, G. Tye, R. Quartey‐Papafio, 2015, Immunity & Ageing.

In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei

L. Durant, D. Bernardo, E. Williamson, 2021, Vaccines.

Role for both myeloid and plasmacytoid DC in driving primary T helper cell response to Burkholderia pseudomallei in healthy individuals

L. Durant, D. Bernardo, E. Williamson, 2020, bioRxiv.

Resolution of allergic airways inflammation but persistence of airway smooth muscle proliferation after repeated allergen exposures

A. Noble, P. Nath, P. Eynott, 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Absence of Galectin‐1 accelerates CD8+ T cell‐mediated graft rejection

R. Lechler, E. Simpson, G. Lombardi, 2012, European journal of immunology.

Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization.

A. Hayday, D. Gibbons, Adrian L. Smith, 2008, Journal of Allergy and Clinical Immunology.

Absence of Galectin‐1 accelerates CD8+ T cell‐mediated graft rejection

R. Lechler, E. Simpson, G. Lombardi, 2012, European journal of immunology.