N. Hashimoto

发表

Activation of the Smad Pathway in Glomeruli from a Spontaneously Diabetic Rat Model, OLETF Rats

A. Nakao, K. Sakurai, K. Yagui, 2004, Nephron Experimental Nephrology.

A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro

S. Takasawa, H. Okamoto, H. Makino, 1998, Diabetologia.

Regulation of Src homology 2-containing protein tyrosine phosphatase by advanced glycation end products: the role on atherosclerosis in diabetes.

H. Makino, M. Taira, H. Sano, 2007, Metabolism: clinical and experimental.

Increased activity and expression of MAP kinase in HCC model rats induced by 3'-methyl-4-dimethylamino-azobenzene.

O. Yokosuka, B. Goldstein, Y. Suzuki, 1999, Journal of hepatology.

Familial type C syndrome of insulin resistance and short stature with possible autosomal dominant transmission.

H. Makino, M. Taira, N. Hashimoto, 1989, Endocrinologia japonica.

Differential effects of RAS inhibitors associated with ACE gene polymorphisms in type 2 diabetic nephropathy.

Y. Suzuki, Y. Saito, K. Yagui, 2006, Diabetes research and clinical practice.

Frequency of Mutations of Insulin Receptor Gene in Japanese Patients With NIDDM

T. Murakami, Y. Ebina, F. Kanai, 1995, Diabetes.

Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study).

H. Onuma, H. Makino, H. Osawa, 2002, Diabetes care.

Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cells.

H. Makino, Y. Saito, H. Sano, 2003, Metabolism: clinical and experimental.

LRP1B is a negative modulator of increased migration activity of intimal smooth muscle cells from rabbit aortic plaques.

W. Schneider, K. Yagui, H. Bujo, 2005, Biochemical and biophysical research communications.

Insulin-sensitive phosphodiesterase and insulin receptor binding in fat cells from spontaneously obese rats

H. Makino, A. Kanatsuka, N. Hashimoto, 1985, Diabetologia.

Insulin Resistance of Fat Cells from Spontaneously Diabetic KK Mice: Analysis of Insulin-sensitive Phosphodiesterase

H. Makino, A. Kanatsuka, N. Hashimoto, 1985, Diabetes.

Insulin receptor gene mutation: a molecular genetical and functional analysis.

H. Makino, Y. Suzuki, M. Taira, 1992, Cellular signalling.

Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor.

Y. Ebina, H. Makino, Y. Suzuki, 1989, Science.

First-phase insulin response to glucose in nonobese or obese subjects with glucose intolerance: analysis by C-peptide secretion rate.

H. Makino, M. Taira, A. Kanatsuka, 1988, Metabolism: clinical and experimental.

Biphasic insulin response to high glucose and a role of protons and calcium.

H. Makino, A. Kanatsuka, T. Yamaguchi, 1987, Endocrinology.

A glycine-1008 to valine mutation in the insulin receptor in a woman with type A insulin resistance.

H. Makino, Y. Suzuki, M. Taira, 1993, The Journal of clinical endocrinology and metabolism.

An Assessment of the New NIH Diagnostic Criteria for Diabetes Mellitus According to Insulin Response in a 75 g Oral Glucose Tolerance Test and Levels of Hemoglobin AIC

H. Makino, A. Kanatsuka, N. Hashimoto, 1982, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Identification of two novel amino acid polymorphisms in beta-cell/liver (GLUT2) glucose transporter in Japanese subjects

G. Bell, H. Makino, A. Kanatsuka, 1995, Diabetologia.

Abnormal calcium handling by perifused pancreatic islets from neonatal streptozotocin diabetic model rats.

H. Makino, A. Kanatsuka, H. Horie, 1987, Metabolism: clinical and experimental.

Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family

S. Seino, G. Bell, H. Makino, 1993, Diabetologia.

Analysis of the insulin-sensitive phosphodiesterase 3B gene in type 2 diabetes.

H. Makino, Y. Suzuki, M. Taira, 2001, Diabetes research and clinical practice.

Detection of an amino acid polymorphism in hormone-sensitive lipase in Japanese subjects.

H. Makino, M. Taira, A. Kanatsuka, 1996, Metabolism: clinical and experimental.

Impaired glucose tolerance is accompanied by decreased insulin sensitivity in tissues of mice implanted with cells that overexpress resistin

K. Yagui, M. Shibasaki, H. Bujo, 2004, Diabetologia.

Defects in insulin binding and receptor kinase in cells from a woman with type A insulin resistance and from her family

H. Makino, Y. Suzuki, M. Taira, 1991, Diabetologia.

A potent activator of PPARα and γ reduces the vascular cell recruitment and inhibits the intimal thickning in hypercholesterolemic rabbits

M. Shibasaki, H. Bujo, Kazuo Takahashi, 2005 .

Mutations in the Hepatocyte Nuclear Factor-4α Gene in Japanese with Non-Insulin-Dependent Diabetes: A Nucleotide Substitution in the Polypyrimidine Tract of Intron 1b

T. Egashira, H. Makino, Y. Suzuki, 2000, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Increased urinary levels of CXCL5, CXCL8 and CXCL9 in patients with Type 2 diabetic nephropathy.

M. Muraguchi, K. Yagui, K. Joh, 2009, Journal of diabetes and its complications.

Effects of monensin on glucose-induced insulin release and 45Ca2+ outflow.

H. Makino, A. Kanatsuka, N. Hashimoto, 1986, Advances in experimental medicine and biology.

Tumor necrosis factor alpha signaling pathway and apoptosis in pancreatic beta cells.

J. Miyazaki, H. Makino, Y. Suzuki, 1999, Metabolism: clinical and experimental.

Augmented gastrin responses in diabetic patients with vagal neuropathy

H. Makino, A. Kanatsuka, N. Hashimoto, 1984, Diabetologia.

Insulin-resistant diabetes associated with partial deletion of insulin-receptor gene

Y. Ebina, Y. Suzuki, M. Taira, 1990, The Lancet.

Tumor necrosis factor alpha signaling pathway and apoptosis in pancreatic β cells

J. Miyazaki, H. Makino, A. Kanatsuka, 1999 .

Molecular cloning of rat Pax4: identification of four isoforms in rat insulinoma cells.

A. Kanatsuka, Y. Saito, K. Sakurai, 1998, Biochemical and biophysical research communications.

Roles of degree of fat deposition and its localization on VEGF expression in adipocytes.

K. Yagui, H. Bujo, Kazuo Takahashi, 2005, American journal of physiology. Endocrinology and metabolism.

Bisphenol A affects glucose transport in mouse 3T3‐F442A adipocytes

K. Sakurai, T. Adachi, C. Mori, 2004, British journal of pharmacology.

Visceral Fat: Higher Responsiveness of Fat Mass and Gene Expression to Calorie Restriction than Subcutaneous Fat

M. Shibasaki, H. Bujo, Kazuo Takahashi, 2003, Experimental biology and medicine.

Elevated serum vascular endothelial growth factor is associated with visceral fat accumulation in human obese subjects

H. Bujo, Y. Saito, Kazuo Takahashi, 2003, Diabetologia.

Insulin resistance and increased pancreatic beta-cell proliferation in mice expressing a mutant insulin receptor (P1195L).

T. Shirasawa, Y. Saito, K. Sakurai, 2006, The Journal of endocrinology.

Insulin resistance and increased pa ncreatic b-cell proliferation in mice expressing a mutant insulin receptor ( P 1195 L )

T. Shirasawa, Y. Saito, K. Sakurai, 2006 .

Role of Src Homology 2–Containing Tyrosine Phosphatase 2 on Proliferation of Rat Smooth Muscle Cells

Yoshifumi Suzuki, S. Mori, N. Hashimoto, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Effects of weight loss in obese subjects with normal fasting plasma glucose or impaired glucose tolerance on insulin release and insulin resistance according to a minimal model analysis.

A. Kanatsuka, K. Yagui, H. Bujo, 2004, Metabolism: clinical and experimental.

Pathophysiologic phenotypes of Japanese subjects with varying degrees of glucose tolerance: using the combination of C-peptide secretion rate and minimal model analysis.

A. Kanatsuka, Y. Saito, K. Sakurai, 2001, Metabolism: clinical and experimental.

Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor

Y. Ebina, H. Makino, Y. Suzuki, 1989 .

Insulin resistance associated with decreased levels of insulin-receptor messenger ribonucleic acid: evidence of a de novo mutation in the maternal allele.

S. Taylor, H. Makino, Y. Suzuki, 1995, The Journal of clinical endocrinology and metabolism.

Abnormal messenger ribonucleic acid (mRNA) transcribed from a mutant insulin receptor gene in a patient with type A insulin resistance

H. Makino, Y. Suzuki, M. Taira, 1992, Diabetologia.

Subcutaneous Fat Modulates Insulin Sensitivity in Mice by Regulating TNF-α Expression in Visceral Fat

K. Yagui, H. Bujo, N. Hashimoto, 2006, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

The acute effects of glycemic control on axonal excitability in human diabetic nerves.

S. Kuwabara, Yoshifumi Suzuki, N. Hashimoto, 2002, Internal medicine.

Mechanisms Involved in the Depleting Effect of Cysteamine on Pancreatic Somatostatin

H. Makino, A. Kanatsuka, N. Hashimoto, 1987, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Modulation of Insulin Action by Fasting: A Study Using a Phosphodiesterase Activation System in Rat Fat Cells

H. Makino, A. Kanatsuka, N. Hashimoto, 1985, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Protein Tyrosine Phosphatase Regulation in Fibroblasts from Patients with an Insulin Receptor Gene Mutation

K. Yagui, F. Shimada, N. Hashimoto, 2008, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.