J. Won

发表

Tumorigenicity of mouse thymoma is suppressed by soluble type II transforming growth factor beta receptor therapy.

Y. Yun, S. Kim, Y. Hong, 1999, Cancer research.

Bispecific Antibodies: A Smart Arsenal for Cancer Immunotherapies

S. H. Lee, Yangsoon Lee, J. Won, 2021, Vaccines.

Rosmarinic Acid Induces Apoptosis of Activated T Cells from Rheumatoid Arthritis Patients via Mitochondrial Pathway

C. Suh, Sungjoo Kim, J. Won, 2006, Journal of Clinical Immunology.

B7-H3×4-1BB bispecific antibody augments antitumor immunity by enhancing terminally differentiated CD8+ tumor-infiltrating lymphocytes

Han Wook Park, Yangsoon Lee, J. Won, 2021, Science Advances.

Beneficial effects of rosmarinic acid on suppression of collagen induced arthritis.

S. Huh, Kyung-Hee Lee, J. Won, 2003, The Journal of rheumatology.

GC1118, a novel anti-EGFR antibody, has potent KRAS mutation-independent antitumor activity compared with cetuximab in gastric cancer

Y. Bang, J. E. Park, D. Oh, 2019, Gastric Cancer.

Design and characterization of non-phosphopeptide inhibitors for Src family SH2 domains.

See-Hyoung Park, J. Won, Keun-Hyeung Lee, 2002, Bioorganic & medicinal chemistry letters.

Through induction of juxtaposition and tyrosine kinase activity of Jak1, X-gene product of hepatitis B virus stimulates Ras and the transcriptional activation through AP-1, NF-kappaB, and SRE enhancers.

Y. Yun, Y. Lee, J. Won, 2001, Biochemical and biophysical research communications.

Rosmarinic acid inhibits Ca2+-dependent pathways of T-cell antigen receptor-mediated signaling by inhibiting the PLC-gamma 1 and Itk activity.

Miae Kang, J. Won, S. Yun, 2003, Blood.

Oral administration of 1, 4-aryl-2-mercaptoimidazole (KRM-III) inhibits T cell proliferation and reduces clinical severity in murine experimental autoimmune encephalomyelitis model

J. Won, Sejin Hwang, M. Hur, 2009 .

A First‐in‐Human Phase I Study of GC1118, a Novel Anti‐Epidermal Growth Factor Receptor Antibody, in Patients with Advanced Solid Tumors

S. Hahn, Y. Bang, J. W. Kim, 2019, The oncologist.

Aurintricarboxylic acid translocates across the plasma membrane, inhibits protein tyrosine phosphatase and prevents apoptosis in PC12 cells.

J. Kang, Hyeongjin Cho, J. Won, 2004, Molecules and cells.

Synergistic immunosuppressive effects of rosmarinic acid and rapamycin in vitro and in vivo1

C. Ahn, Miae Kang, J. Won, 2003, Transplantation.

Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade

E. Shin, Su‐Hyung Park, Wenqing Jiang, 2021, Journal for ImmunoTherapy of Cancer.

Oral Administration of 1,4-Aryl-2-mercaptoimidazole Inhibits T-Cell Proliferation and Reduces Clinical Severity in the Murine Experimental Autoimmune Encephalomyelitis Model

Sungjoo Kim, Yeup Yoon, E. Jung, 2009, Journal of Pharmacology and Experimental Therapeutics.

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab

K. Cibulskis, S. Gabriel, E. Lander, 2014, Molecular Cancer.

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab

K. Cibulskis, S. Gabriel, E. Lander, 2014, Molecular Cancer.

Rosmarinic Acid Induces p56lck-Dependent Apoptosis in Jurkat and Peripheral T Cells via Mitochondrial Pathway Independent from Fas/Fas Ligand Interaction 1

Y. Yun, J. Won, Yun-Gyoung Hur, 2004, The Journal of Immunology.

Rosmarinic Acid Induces p56lck-Dependent Apoptosis in Jurkat and Peripheral T Cells via Mitochondrial Pathway Independent from Fas/Fas Ligand Interaction 1

Y. Yun, J. Won, Yun-Gyoung Hur, 2004, The Journal of Immunology.

Induction of Angiogenesis by Expression of Soluble Type II Transforming Growth Factor-β Receptor in Mouse Hepatoma*

M. Nam, P. Ryu, J. Won, 2001, The Journal of Biological Chemistry.

T-Cell–Targeted Signaling Inhibitors

J. Won, G. Lee, 2008, International reviews of immunology.

Inhibition of NF-κB activation by merlin

Hongtae Kim, S. Rha, Young Hoon Kim, 2002 .

Inhibition of NF-jB activation by merlin q

Hongtae Kim, S. Rha, H. Rha, 2002 .

Rosmarinic acid inhibits TCR‐induced T cell activation and proliferation in an Lck‐dependent manner

Jonghwa Won, Changwon Park, See-Hyoung Park, 2003, European journal of immunology.

Development of Novel Small Chemical Inhibitors for Lck SH Domain with in vitro T-cell Inhibitory Activity

See-Hyoung Park, Hyeongjin Cho, Miae Kang, 2006 .

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab

K. Cibulskis, S. Gabriel, E. Lander, 2014, Molecular Cancer.

The structure-activity relationship of the series of non-peptide small antagonists for p56lck SH2 domain.

See-Hyoung Park, Hyeongjin Cho, Miae Kang, 2007, Bioorganic & medicinal chemistry.

Abstract 4246: ABL103, A novel T-cell engaging bispecific antibody, exhibits potent in vitro and vivo antitumor activity and low toxicity via B7-H4 dependent 4-1BB activation in tumor microenvironment

J. Won, Kyeongsu Park, Minji Ko, 2022, Cancer Research.

Inhibition of NF-kappaB activation by merlin.

Hongtae Kim, S. Rha, Young Hoon Kim, 2002, Biochemical and biophysical research communications.

GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands

D. Nam, Hyun-soo Cho, Y. Kim, 2015, Molecular Cancer Therapeutics.

Whole Transcriptome Analysis Identifies TNS4 as a Key Effector of Cetuximab and a Regulator of the Oncogenic Activity of KRAS Mutant Colorectal Cancer Cell Lines

Jeonghee Cho, Nayoung Kim, Wonkyun Kim, 2019, Cells.

Abstract LB-114: GC1118, a new anti-EGFR antibody overcome acquired resistance to cetuximab in colorectal cancer xenograft model

Sujeong Kim, Kyuhyun Lee, J. Won, 2016 .

Use of a Target‐Mediated Drug Disposition Model to Predict the Human Pharmacokinetics and Target Occupancy of GC1118, an Anti‐epidermal Growth Factor Receptor Antibody

Jongtae Lee, D. Yim, Kyuhyun Lee, 2017, Basic & clinical pharmacology & toxicology.

LAG-3xPD-L1 bispecific antibody potentiates antitumor responses of T cells through dendritic cell activation

S. Oh, H. Song, Yoon Park, 2022, Molecular therapy : the journal of the American Society of Gene Therapy.

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab

K. Cibulskis, S. Gabriel, E. Lander, 2014, Molecular Cancer.

From Fas/fas Ligand Interaction via Mitochondrial Pathway Independent Apoptosis in Jurkat and Peripheral T Cells -dependent Lck Rosmarinic Acid Induces P56

Y. Yun, J. Won, Yun-Gyoung Hur, 2013 .

Asymmetric anti-CLL-1×CD3 bispecific antibody, ABL602 2+1, with attenuated CD3 affinity endows potent antitumor activity but limited cytokine release

Dong-Yeop Shin, J. Won, Yong-gyu Son, 2023, Journal for immunotherapy of cancer.

A Novel Asymmetrical Anti-CLL-1×CD3 Bispecific Antibody, ABL602, Induces Potent CLL1-Specific Antitumor Activity with Minimized Sensitization of Pro-Inflammatory Cytokines

J. Won, Shinai Lee, Hye-Ryeon Park, 2021, Blood.