T. Umstead

发表

Increased surfactant protein-A levels in patients with newly diagnosed idiopathic pulmonary fibrosis.

M. Mejía, M. Selman, A. Pardo, 2004, Chest.

Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis

Zhenwu Lin, A. Estrada, M. Selman, 2003, Human Genetics.

SP-A1 and SP-A2 variants differentially enhance association of Pseudomonas aeruginosa with rat alveolar macrophages.

J. Floros, Weixiong Huang, D. Phelps, 2005, American journal of physiology. Lung cellular and molecular physiology.

SP-A 1 and SPA 2 variants differentially enhance association of Pseudomonas aeruginosa with rat alveolar macrophages

J. Floros, Weixiong Huang, D. Phelps, 2004 .

The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome

W. Freeman, J. Floros, R. Haque, 2009, Proteome Science.

Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants.

Guirong Wang, Xiaoxuan Guo, J. Floros, 2008, American journal of physiology. Lung cellular and molecular physiology.

SH3GLB2/endophilin B2 regulates lung homeostasis and recovery from severe influenza A virus infection

T. Abraham, S. Diangelo, T. Cooper, 2017, Scientific Reports.

Age-related changes in the expression and oxidation of bronchoalveolar lavage proteins in the rat.

W. Freeman, V. Chinchilli, D. Phelps, 2009, American journal of physiology. Lung cellular and molecular physiology.

Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.

J. Floros, D. Phelps, T. Umstead, 2014, Journal of proteomics.

In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement

C. Yengo, J. Floros, D. Phelps, 2011, Proteome Science.

Down-regulation of 14-3-3 isoforms and annexin A5 proteins in lung adenocarcinoma induced by the tobacco-specific nitrosamine NNK in the A/J mouse revealed by proteomic analysis.

Arunangshu Das, K. El-Bayoumy, C. Aliaga, 2009, Journal of Proteome Research.

Dual-Platform Proteomics Study of Plasma Biomarkers in Pediatric Patients Undergoing Cardiopulmonary Bypass

K. Vrana, W. Freeman, A. Ündar, 2010, Pediatric Research.

Cyclic Changes in the Level of the Innate Immune Molecule, Surfactant Protein‐A, and Cytokines in Vaginal Fluid

G. E. Sousa, K. Ahn, J. Weisz, 2012, American journal of reproductive immunology.

Higher serum PD‐L1 level predicts increased overall survival with lapatinib versus trastuzumab in the CCTG MA.31 phase 3 trial

Bingshu E. Chen, S. Aparicio, K. Gelmon, 2020, Cancer.

Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome

J. Floros, N. Thorenoor, D. Phelps, 2019, Front. Immunol..

Effect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant response.

J. López-Barneo, A. Pascual, J. Pérez-Gil, 2014, Journal of proteomics.

An Electrochemical Biosensor for Rapid Detection of Pediatric Bloodstream Infections

P. Wong, N. Thomas, Ming Wang, 2017, SLAS technology.

Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice.

Guirong Wang, J. Floros, D. Phelps, 2012, Microbial pathogenesis.

Histopathologic evaluation of lung and extrapulmonary tissues show sex differences in Klebsiella pneumoniae - infected mice under different exposure conditions.

T. Cooper, Guirong Wang, J. Floros, 2011, International Journal of Physiology, Pathophysiology and Pharmacology.

Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure

Guirong Wang, J. Floros, D. Phelps, 2019, Front. Immunol..

Surfactant Protein A2 (SP-A2) Variants Expressed in CHO Cells Stimulate Phagocytosis of Pseudomonas aeruginosa More than Do SP-A1 Variants

Guirong Wang, J. Floros, N. Thomas, 2007, Infection and Immunity.

Characterization of a human surfactant protein A1 (SP-A1) gene-specific antibody; SP-A1 content variation among individuals of varying age and pulmonary health.

Guirong Wang, J. Floros, M. Kavuru, 2007, American journal of physiology. Lung cellular and molecular physiology.

Human SPA protein variants derived from one or both genes stimulate TNF-a production in the THP-1 cell line

Guirong Wang, J. Floros, D. Phelps, 2000 .

Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line.

Guirong Wang, J. Floros, G. Wang, 2000, American journal of physiology. Lung cellular and molecular physiology.

Effect of low doses of lipopolysaccharide prior to ozone exposure on bronchoalveolar lavage: Differences between wild type and surfactant protein A-deficient mice.

K. Ahn, J. Floros, R. Haque, 2009, Pneumon.

Hyperoxia-induced alterations in the pulmonary proteome of juvenile rats

D. Phelps, T. Umstead, J. Shenberger, 2013, Experimental lung research.

Effect of ozone exposure and infection on bronchoalveolar lavage: sex differences in response patterns.

Guirong Wang, J. Floros, R. Haque, 2014, Toxicology letters.

SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation

N. Christensen, S. Diangelo, P. Silveyra, 2015, PloS one.

Extracellular matrix-inspired inhalable aerogels for rapid clearance of pulmonary tuberculosis.

Scott H. Medina, T. Umstead, E. Halstead, 2021, Biomaterials.

Housing conditions modulate the severity of Mycoplasma pulmonis infection in mice deficient in class A scavenger receptor.

K. Dybvig, T. Cooper, J. L. Booth, 2014, Comparative medicine.

Survival of Surfactant Protein-A1 and SP-A2 Transgenic Mice After Klebsiella pneumoniae Infection, Exhibits Sex-, Gene-, and Variant Specific Differences; Treatment With Surfactant Protein Improves Survival

J. Floros, N. Thorenoor, D. Phelps, 2018, Front. Immunol..

Modulatory effects of ozone on THP-1 cells in response to SP-A stimulation.

B. Janic, J. Floros, D. Phelps, 2005, American journal of physiology. Lung cellular and molecular physiology.

The effect of ozone exposure on the ability of human surfactant protein a variants to stimulate cytokine production.

Guirong Wang, J. Floros, D. Phelps, 2001, Environmental health perspectives.

Effects of surfactant protein A and surfactant lipids on lymphocyte proliferation in vitro.

S. Kremlev, D. Phelps, T. Umstead, 1994, The American journal of physiology.

An in vitro cell model system for the study of the effects of ozone and other gaseous agents on phagocytic cells.

B. Janic, J. Floros, D. Phelps, 2003, Journal of immunological methods.

Surfactant protein A regulates cytokine production in the monocytic cell line THP-1.

S. Kremlev, D. Phelps, T. Umstead, 1997, The American journal of physiology.

Secretion of surfactant protein A from rat type II pneumocytes.

D. Phelps, T. Umstead, S. Rooney, 1993, The American journal of physiology.

Differences in the Alveolar Macrophage Proteome in Transgenic Mice Expressing Human SP-A1 and SP-A2

Guirong Wang, J. Floros, D. Phelps, 2013 .

Differences in the alveolar macrophage proteome in transgenic mice expressing human SP-A1 and SP-A2.

Guirong Wang, P. Silveyra, J. Floros, 2013, Journal of proteomics and genomics research.

All trans-retinoic acid modulates hyperoxia-induced suppression of NF-kB-dependent Wnt signaling in alveolar A549 epithelial cells

P. Silveyra, N. Tsotakos, T. Umstead, 2022, PloS one.

Disruption of the surfactant protein A receptor SP-R210L (CD245α/MYO18Aα) alters respiratory function and iron sequestration in alveolar macrophages of aged mice

Amy C. Arnold, S. Diangelo, T. Cooper, 2021, bioRxiv.

Differences in the BAL proteome after Klebsiella pneumoniae infection in wild type and SP-A-/- mice

W. Freeman, J. Floros, Mehboob Ali, 2010, Proteome Science.

Researchin the BAL proteome after Klebsiella pneumoniae infection in wild type and SP-A-/- mice

W. Freeman, J. Floros, Mehboob Ali, 2010 .

Lower Respiratory Tract Delivery, Airway Clearance, and Preclinical Efficacy of Inhaled GM-CSF in a Post-influenza Pneumococcal Pneumonia Model.

Ming Wang, T. Umstead, Z. Chroneos, 2020, American journal of physiology. Lung cellular and molecular physiology.

Surfactant protein A activates NF-kappa B in the THP-1 monocytic cell line.

M. Koptides, J. Floros, D. Phelps, 1997, The American journal of physiology.

Penn State Hershey--center for pediatric cardiovascular research.

Kyung Sun, Kerem Pekkan, Ronald Wilson, 2009, Artificial organs.

Pediatric cardiopulmonary bypass circuits: a review of studies conducted at the Penn State Pediatric Cardiac Research Laboratories.

A. Undar, K. Vrana, W. Freeman, 2009, The journal of extra-corporeal technology.

Surfactant protein A, an innate immune factor, is expressed in the vaginal mucosa and is present in vaginal lavage fluid

Zhenwu Lin, J. Weisz, J. Floros, 2004, Immunology.

Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116.

Todd M Umstead, Lino Tessarollo, Kunio Nagashima, 2013, Cell reports.

SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved

J. Floros, N. Thorenoor, D. Phelps, 2017, Biology of Sex Differences.

A Pilot Proteomic Study of Vestibular Fluid From Patients With Vulvodynia

J. Weisz, J. Floros, Debra A. Shearer, 2022, Journal of lower genital tract disease.

Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A

J. Floros, D. Phelps, T. Umstead, 2012, Proteome Science.

Altered chemokine response in an animal model of multiple organ dysfunction syndrome induced by zymosan.

N. Thomas, D. Phelps, T. Umstead, 2005, Journal of pediatric surgery.

Surfactant protein A alters endosomal trafficking of influenza A virus in macrophages

J. Yewdell, Yan Chen, Hannah M. Atkins, 2023, Frontiers in Immunology.

GM-CSF overexpression after influenza a virus infection prevents mortality and moderates M1-like airway monocyte/macrophage polarization

Y. Kawasawa, P. Silveyra, T. Umstead, 2018, Respiratory Research.

Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages.

Chunhua Song, Yoshinori Takahashi, E. Yau, 2021, Immunobiology.

SH3GLB2/endophilin B2 regulates lung homeostasis and recovery from severe influenza A virus infection

T. Abraham, S. Diangelo, T. Cooper, 2017, Scientific Reports.

Factors affecting SP-A-mediated phagocytosis in human monocytic cell lines.

J. Floros, Jianqiang Ding, D. Phelps, 2004, Respiratory medicine.

Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences

J. Floros, N. Thorenoor, D. Phelps, 2018, Respiratory Research.

Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice.

Xiaoxuan Guo, J. Floros, S. Hawgood, 2007, Toxicology and applied pharmacology.

Knockdown of Drosha in human alveolar type II cells alters expression of SP-A in culture: A pilot study

S. Diangelo, P. Silveyra, J. Floros, 2014, Experimental lung research.

Cytokine Panels and Pediatric Acute Respiratory Distress Syndrome: A Translational Investigation*

S. Hicks, N. Thomas, Ming Wang, 2020, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

Structural and Functional Determinants of Rodent and Human Surfactant Protein A: A Synthesis of Binding and Computational Data

P. Silveyra, J. Floros, N. Thomas, 2019, Front. Immunol..

Impact of Ozone, Sex, and Gonadal Hormones on Bronchoalveolar Lavage Characteristics and Survival in SP-A KO Mice Infected with Klebsiella pneumoniae

Guirong Wang, J. Floros, D. Phelps, 2020, Microorganisms.

Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages

Chunhua Song, Yoshinori Takahashi, E. Yau, 2021, bioRxiv.

Surfactant protein-A levels increase during Pneumocystis carinii pneumonia in the rat.

R. Rose, J. Fishman, D. Phelps, 1996, The European respiratory journal.

Sex differences in the impact of ozone on survival and alveolar macrophage function of mice after Klebsiella pneumoniae infection

V. Chinchilli, J. Floros, D. Phelps, 2008, Respiratory research.

Surfactant p protein-A llevels iincrease d during Pneumocystis c carinii pneumonia iin tthe rrat

R. Rose, J. Fishman, D. Phelps, 1996 .

Inhibition of ozone-induced SP-A oxidation by plant polyphenols

D. Kouretas, S. Haroutounian, D. Stagos, 2007, Free radical research.

SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved

J. Floros, N. Thorenoor, D. Phelps, 2017, Biology of Sex Differences.

Surfactant protein A increases matrix metalloproteinase-9 production by THP-1 cells.

D. Phelps, T. Umstead, L. G. Vázquez de Lara, 2003, American journal of physiology. Lung cellular and molecular physiology.

The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome

W. Freeman, J. Floros, R. Haque, 2009, Proteome Science.

Proteomic profiling of human plasma by iTRAQ reveals down-regulation of ITI-HC3 and VDBP by cigarette smoking.

Jason Liao, Todd M Umstead, Anne Stanley, 2011, Journal of proteome research.

The toll of ozone

J. Floros, D. Phelps, T. Umstead, 2011 .

Knockdown of Drosha in human alveolar type II cells alters expression of SP-A in culture: A pilot study

S. Diangelo, P. Silveyra, J. Floros, 2014, Experimental lung research.

Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice.

Guirong Wang, J. Floros, D. Phelps, 2012, Microbial pathogenesis.

In Vitro Exposure of Proteins to Ozone

Guirong Wang, J. Floros, D. Phelps, 2002, Toxicology mechanisms and methods.

Age-related changes in the expression and oxidation of bronchoalveolar lavage proteins in the rat.

W. Freeman, V. Chinchilli, D. Phelps, 2009, American journal of physiology. Lung cellular and molecular physiology.

SP-R210 isoforms of Myosin18A modulate endosomal sorting and recognition of influenza A virus infection in macrophages.

T. Umstead, Z. Chroneos, Linlin Yang, 2023, Microbes and infection.