P. Krosky

发表

Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core.

K. Fan, R. Gregg, Suresh B. Singh, 2016, Bioorganic & medicinal chemistry letters.

Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist.

K. Fan, R. Gregg, Zhijie Liu, 2016, Journal of medicinal chemistry.

Immunohistochemical Discrimination Between the ASPL-TFE3 Fusion Proteins of Alveolar Soft Part Sarcoma

R. Shoemaker, M. Raffeld, S. Kenney, 2008, Journal of pediatric hematology/oncology.

A Recombinant Human Cytomegalovirus with a Large Deletion in UL97 Has a Severe Replication Deficiency

D. Coen, G. Pari, N. Gao, 1999, Journal of Virology.

Phosphorylation of the RNA polymerase II carboxyl-terminal domain in human cytomegalovirus-infected cells and in vitro by the viral UL97 protein kinase.

D. Coen, M. Baek, P. Krosky, 2004, Virology.

Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase type 1.

Suresh B. Singh, P. Carroll, D. Claremon, 2011, Journal of medicinal chemistry.

The Human Cytomegalovirus UL44 Protein Is a Substrate for the UL97 Protein Kinase

D. Coen, M. Baek, R. Harvey, 2003, Journal of Virology.

The Human Cytomegalovirus UL 44 Protein Is a Substrate for the UL 97 Protein Kinase

D. Coen, M. Baek, R. Harvey, 2003 .

Relationship between Autophosphorylation and Phosphorylation of Exogenous Substrates by the Human Cytomegalovirus UL97 Protein Kinase

D. Coen, M. Baek, P. Krosky, 2002, Journal of Virology.

Pharmacological characterization of the selective 11β-hydroxysteroid dehydrogenase 1 inhibitor, BI 135585, a clinical candidate for the treatment of type 2 diabetes.

H. Nar, B. Hamilton, D. Lala, 2015, European journal of pharmacology.

Influence of sub-chronic selective 11β-hydroxysteroid dehydrogenase 1 inhibition on the hypothalamic-pituitary-adrenal axis in female cynomolgus monkeys.

B. Hamilton, D. Lala, D. Claremon, 2016, European journal of pharmacology.

Phosphorylation of β-d-Ribosylbenzimidazoles Is Not Required for Activity against Human Cytomegalovirus

R. Ptak, M. Nassiri, P. Krosky, 2002, Antimicrobial Agents and Chemotherapy.

Discovery of BI 135585, an in vivo efficacious oxazinanone-based 11β hydroxysteroid dehydrogenase type 1 inhibitor.

Suresh B. Singh, B. Hamilton, D. Lala, 2017, Bioorganic & medicinal chemistry.

Differences in DNA Packaging Genes and Sensitivity to Benzimidazole Ribonucleosides between Human Cytomegalovirus Strains AD169 and Towne

R. Ptak, P. Krosky, L. Townsend, 2000, Antiviral chemistry & chemotherapy.

The Human Cytomegalovirus UL97 Protein Kinase, an Antiviral Drug Target, Is Required at the Stage of Nuclear Egress

D. Coen, M. Baek, P. Krosky, 2003, Journal of Virology.

Resistance of Human Cytomegalovirus to Benzimidazole Ribonucleosides Maps to Two Open Reading Frames: UL89 and UL56

R. Ptak, P. Krosky, L. Townsend, 1998, Journal of Virology.

Specific Phosphorylation of Exogenous Protein and Peptide Substrates by the Human Cytomegalovirus UL97 Protein Kinase

D. Coen, M. Baek, P. Krosky, 2002, The Journal of Biological Chemistry.

A high-throughput fluorescence-anisotropy screen that identifies small molecule inhibitors of the DNA binding of B-ZIP transcription factors.

D. Scudiero, R. Shoemaker, C. Vinson, 2005, Analytical biochemistry.

Discovery and optimization of adamantyl carbamate inhibitors of 11β-HSD1.

R. Gregg, Suresh B. Singh, H. Nar, 2010, Bioorganic & medicinal chemistry letters.

Spirocyclic ureas: orally bioavailable 11 beta-HSD1 inhibitors identified by computer-aided drug design.

Suresh B. Singh, D. Claremon, C. Tice, 2010, Bioorganic & medicinal chemistry letters.