Stephen D. Lee

发表

Liver X receptors at the intersection of lipid metabolism and atherogenesis.

P. Tontonoz, Stephen D. Lee, 2015, Atherosclerosis.

Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery

Dion R. Brocks, D. Brocks, K. Wasan, 2008, Nature Reviews Drug Discovery.

Eosinophils in Fat: Pink Is the New Brown

P. Tontonoz, Stephen D. Lee, 2014, Cell.

Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

Luis C. Santos, Brandon J Thomas, Xia Yang, 2019, bioRxiv.

Long circulating lipid nanocapsules for drug detoxification.

J. Leroux, K. Wasan, A. Dhanikula, 2007, Biomaterials.

The Influence of Hyperlipoproteinemia on in Vitro Distribution of Amiodarone and Desethylamiodarone in Human and Rat Plasma

D. Brocks, K. Wasan, A. Shayeganpour, 2007, Pharmaceutical Research.

Brap regulates liver morphology and hepatocyte turnover via modulation of the Hippo pathway

P. Tontonoz, Xu Xiao, Stephen D. Lee, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Suitability of LLC-PK1 pig kidney cells for the study of drug action on renal cell cholesterol uptake: identification and characterization of low-density lipoprotein receptors.

K. Wasan, Stephen D. Lee, K. Sachs-Barrable, 2005, Journal of pharmacological and toxicological methods.

Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism

K. Wasan, Stephen D. Lee, Sheila J. Thornton, 2008, Lipids in Health and Disease.

Evaluation of the contribution of the ATP binding cassette transporter, P-glycoprotein, to in vivo cholesterol homeostasis.

K. Wasan, Stephen D. Lee, Sheila J. Thornton, 2013, Molecular pharmaceutics.

Transgenic Expression of Dominant-Active IDOL in Liver Causes Diet-Induced Hypercholesterolemia and Atherosclerosis in Mice

A. Lusis, P. Tontonoz, Cynthia Hong, 2014, Circulation research.

Assessing Lipid Lowering and Plasma Cholesteryl Ester Transfer Protein Activity of Simvastatin Following Administration to Rabbits Fed a High Fat/Cholesterol Diet

K. Wasan, Stephen D. Lee, O. Sivak, 2006, Drug development and industrial pharmacy.

Influence of Plasma Cholesterol and Triglyceride Concentrations and Eritoran (E5564) Micelle Size on its Plasma Pharmacokinetics and Ex Vivo Activity Following Single Intravenous Bolus Dose Into Healthy Female Rabbits

D. Rossignol, K. Wasan, Stephen D. Lee, 2007, Pharmaceutical Research.

sLRP1ng Up Glucose: LRP1 Regulates Hepatic Insulin Responses

P. Tontonoz, Stephen D. Lee, 2016, EBioMedicine.

Inhibition of Cholesterol Absorption: Targeting the Intestine

P. Gershkovich, K. Wasan, Stephen D. Lee, 2012, Pharmaceutical Research.

Enhancing drug absorption using lipids: a case study presenting the development and pharmacological evaluation of a novel lipid-based oral amphotericin B formulation for the treatment of systemic fungal infections.

E. Wasan, K. Wasan, Kristina Sachs-Barrable, 2008, Advanced drug delivery reviews.

RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs

D. Black, S. Young, S. Mandrup, 2017, The Journal of clinical investigation.

NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice

M. Pellegrini, D. Shih, A. Lusis, 2021, Scientific Reports.

Dose-Dependent Targeted Suppression of P-glycoprotein Expression and Function in Caco-2 Cells

K. Wasan, Stephen D. Lee, J. Osei-Twum, 2013, Molecular pharmaceutics.

Lipids in Health and Disease

K. Wasan, Stephen D. Lee, Sheila J. Thornton, 2008 .

Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells.

K. Wasan, Kristina Sachs-Barrable, Kishor M Wasan, 2007, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Evaluation of the in vivo role of p-glycoprotein in the maintenance of cholesterol homeostasis

Stephen D. Lee, 2012 .

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

E. Ikonen, S. Young, J. Schwabe, 2018, Cell.

Polymorphisms of microsomal epoxide hydrolase in French vinyl chloride workers.

P. Brandt-Rauf, M. Marion, Stephen D. Lee, 2005, International journal of occupational medicine and environmental health.

Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis

Julia J. Mack, M. Fishbein, A. Lusis, 2015, The Journal of experimental medicine.

IDOL regulates systemic energy balance through control of neuronal VLDLR expression

Richard G. Lee, Xia Yang, Pernilla Eliasson, 2019, Nature Metabolism.

Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake

Julia J. Mack, S. Young, J. Schwabe, 2023, bioRxiv.

Lipids in Health and Disease Effect of Dietary Fat on Hepatic Liver X Receptor Expression in P-glycoprotein Deficient Mice: Implications for Cholesterol Metabolism

K. Wasan, Stephen D. Lee, Sheila J. Thornton, 2022 .

Inhibition of Cholesterol Absorption: Targeting the Intestine

P. Gershkovich, K. Wasan, Stephen D. Lee, 2012, Pharmaceutical Research.