V. Timofeev

发表

Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.

S. Stulov, Olga V. Mankevich, N. O. Dugin, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and molecular modeling of (4′R)- and (4′S)- 4′-substituted 2′-{[(E)-androst-5-en-17-ylidene]-methyl}oxazolines

A. Veselovsky, S. Stulov, Olga V. Mankevich, 2013, Steroids.

22,23-Epoxides of Sitosterol and Related 7-Oxygenated Δ5-Sterols

V. Timofeev, A. Misharin, Y. Tkachev, 2005, Russian Journal of Bioorganic Chemistry.

Analysis of mobility of protein side chains by spin label technique

V. Tsetlin, V. Timofeev, 1983, Biophysics of structure and mechanism.

Novel oxazolinyl derivatives of pregna-5,17(20)-diene as 17α-hydroxylase/17,20-lyase (CYP17A1) inhibitors

A. Veselovsky, A. Kuzikov, V. Shumyantseva, 2014, Steroids.

[17(20)E]- and [17(20)Z]-pregna-5,17(20)-dien-21-oylamides. Facile synthesis and primary evaluation for cancer cells proliferation.

M. Zavialova, S. Stulov, R. Novikov, 2010, Bioorganic & medicinal chemistry letters.

Synthesis of New Derivatives of Protoporphyrin IX and Chlorophyll a

G. V. Ponomarev, I. Konstantinov, V. Timofeev, 2005 .

Oxazolinyl derivatives of [17(20)E]-21-norpregnene differing in the structure of A and B rings. Facile synthesis and inhibition of CYP17A1 catalytic activity

A. Veselovsky, A. Kuzikov, V. Shumyantseva, 2016, Steroids.

Citrobacter freundii Methionine γ-Lyase: The Role of Serine 339 in the Catalysis of γ- and β-Elimination Reactions

T. Demidkina, V. Timofeev, Y. Tkachev, 2022, Acta naturae.

The role of active site tyrosine 58 in Citrobacter freundii methionine γ-lyase.

T. Demidkina, V. Timofeev, Y. Tkachev, 2015, Biochimica et biophysica acta.

Comparison of [17(20)E]-21-Norpregnene oxazolinyl and benzoxazolyl derivatives as inhibitors of CYP17A1 activity and prostate carcinoma cells growth

A. Kuzikov, V. Shumyantseva, G. Morozevich, 2018, Steroids.

Extracellular portions of HLA antigens are not compact globulae.

E. Pankratova, V. Timofeev, R. Nezlin, 1987, Molecular immunology.

EPR spin probe and spin label studies of some low molecular and polymer micelles

V. Timofeev, A. Wasserman, V. Kasaikin, 1998 .

The difference between ADP‐beryllium fluoride and ADP‐aluminium fluoride complexes of the spin‐labeled myosin subfragment 1

V. Timofeev, D. Levitsky, M. Ponomarev, 1995, FEBS letters.

New steroidal oxazolines, benzoxazoles and benzimidazoles related to abiraterone and galeterone

A. Veselovsky, V. Pokrovsky, G. Morozevich, 2020, Steroids.

Novel side chain modified Δ8(14)-15-ketosterols

G. Morozevich, V. Timofeev, A. Misharin, 2007, Steroids.

Δ5-7-Ketosterols with modified side chain: The synthesis and the effects on viability and cholesterol biosynthesis in Hep G2 cells

G. Morozevich, V. Timofeev, A. Misharin, 2006, Russian Journal of Bioorganic Chemistry.

New Δ8(14)-15-Ketosterols with an Oxygenated Side Chain

V. Timofeev, A. Misharin, Y. Tkachev, 2005, Russian Journal of Bioorganic Chemistry.

Uniform EPR Spectra Analysis of Spin-Labeled Macromolecules by Temperature and Viscosity Dependences

V. Timofeev, Y. Tkachev, 2012 .

Complexes of Donor–Acceptor Cyclopropanes with Tin, Titanium, and Gallium Chlorides — Mechanism Studies

Yu. V. Tomilov, R. Novikov, V. Timofeev, 2012 .

Chlorin e6-cholesterol conjugate and its copper complex. Simple synthesis and entrapping in phospholipid vesicles.

G. V. Ponomarev, V. Timofeev, A. Misharin, 2010, Bioorganic & medicinal chemistry letters.

Six-Membered Cyclic Nitroso Acetals: Synthesis and Studies of the Nitrogen Inversion Process of N-Silyloxy-3,6-dihydro-2H-1,2-oxazines

Y. Nelyubina, S. Ioffe, R. Novikov, 2016 .

Microwave-Assisted Synthesis of α-Amino Phosphonates Derived from Formylporphyrins of Natural Origin

I. Beletskaya, G. V. Ponomarev, I. Konstantinov, 2003 .

New dimerization and cascade oligomerization reactions of dimethyl 2-phenylcyclopropan-1,1-dicarboxylate catalyzed by Lewis acids

Yu. V. Tomilov, R. Novikov, V. Timofeev, 2011 .

Synthesis and Structures of Cyclopropanedicarboxylate Gallium Complexes

Yu. V. Tomilov, R. Novikov, V. Timofeev, 2015 .

[4 + 2] Annulation of Donor-Acceptor Cyclopropanes with Acetylenes Using 1,2-Zwitterionic Reactivity.

D. A. Denisov, Yu. V. Tomilov, R. Novikov, 2017, The Journal of organic chemistry.

Donor-Acceptor Cyclopropanes as 1,2-Dipoles in GaCl3-Mediated [4 + 2]-Annulation with Alkenes: Easy Access to the Tetralin Skeleton.

Yu. V. Tomilov, R. Novikov, V. Timofeev, 2015, The Journal of organic chemistry.

Stereoselective double lewis acid/organo-catalyzed dimerization of donor-acceptor cyclopropanes into substituted 2-oxabicyclo[3.3.0]octanes.

Yu. V. Tomilov, R. Novikov, V. Timofeev, 2012, The Journal of organic chemistry.

Iminoxyl Radical‐Based Strategy for Intermolecular CO Bond Formation: Cross‐Dehydrogenative Coupling of 1,3‐Dicarbonyl Compounds with Oximes

A. Terent’ev, R. Novikov, V. Timofeev, 2014 .

A new type of donor-acceptor cyclopropane reactivity: the generation of formal 1,2- and 1,4-dipoles.

Yu. V. Tomilov, R. Novikov, V. Timofeev, 2014, Angewandte Chemie.

Synthesis of secasterol and 24-episecasterol and their toxicity for MCF-7 cells

V. Timofeev, A. Misharin, Y. Tkachev, 2010, Russian Journal of Bioorganic Chemistry.

Toxicity of (22R,23R)-22,23-dihydroxystigmastane derivatives to cultured cancer cells

V. Timofeev, A. Misharin, A. R. Mehtiev, 2010, Steroids.

Oxidative C ? O Cross‐Coupling of 1,3‐Dicarbonyl Compounds and Their Heteroanalogues with N‐Substituted Hydroxamic Acids and N‐Hydroxyimides

A. Terent’ev, Z. Starikova, V. Timofeev, 2013 .

Kinetic and spectral parameters of interaction of Citrobacter freundii methionine γ-lyase with amino acids

T. Demidkina, V. Timofeev, Y. Tkachev, 2010, Biochemistry (Moscow).

Palmitates of Isomeric 15-Oxygenated Δ8(14)-Sterols

V. Timofeev, A. Misharin, D. Ignatov, 2004, Russian Journal of Bioorganic Chemistry.

Stereospecificity of isotopic exchange of C-α-protons of glycine catalyzed by three PLP-dependent lyases: the unusual case of tyrosine phenol-lyase

V. V. Komissarov, L. N. Zakomirdina, T. Demidkina, 2011, Amino Acids.

Conjugates of 17-substituted testosterone and epitestosterone with pyropheophorbide a differing in the length of linkers

G. V. Ponomarev, P. N. Solyev, M. Zavialova, 2018, Steroids.

Revealing of the Spin-Spin Interaction Due to Incorporating a Spin Label in the Carbohydrate Parts of Immuniglobulins M and G

V. Timofeev, V. Alyoshkin, V. A. Lapuk, 2002, Journal of biomolecular structure & dynamics.

Synthesis of Pyrazoleporphyrins and Pyrazolechlorins by Cyclization of Peripheral ββ-Diketone Groups of Porphyrins and Chlorins with Phenylhydrazines

G. V. Ponomarev, I. Konstantinov, V. Timofeev, 2003 .

Synthesis of 21-nitrogen substituted pregna-5,17(20)-dienes from pregnenolone

M. Zavialova, S. Stulov, R. Novikov, 2012, Steroids.

A new theoretical approach to simulation of EPR spectra of spin-labels in protein and membrane systems

V. Timofeev, Y. Tkachev, 2014 .

Studies on the mechanism of action of the histone kinase dependent on adenosine 3',5'-monophosphate. Investigation of protein-protein interaction by electron spin-resonance spectroscopy and stopped-flow methods.

A G Gabibov, I. Smirnov, A. Gabibov, 1983, European journal of biochemistry.

Is the Fab-Fragment from Monoclonal Rheumatoid IgM Flexible? A Spin Label Dynamics Study

V. Novikov, V. Timofeev, Y. Tkachev, 2005, Journal of biomolecular structure & dynamics.

(22R,23R)-3β-hydroxy-22,23-epoxy-5α-ergost-8(14)-en-15-one: Improved synthesis and toxicity to MCF-7 cells

V. Timofeev, A. Misharin, A. R. Mehtiev, 2008, Russian Journal of Bioorganic Chemistry.

Influence of Intermolecular Interactions on the DNA Conformation

G. Malenkov, V. Timofeev, A. V. Gagua, 1979 .

Temperature-induced changes in copper centers and protein conformation of two fungal laccases from Coriolus hirsutus and Coriolus zonatus.

W. Pfeil, O. Koroleva, E. Stepanova, 2001, Biochimica et biophysica acta.

Oxazoline derivatives of [17(20)E]-21-norpregnene – inhibitors of CYP17A1 activity and proliferation of prostate carcinoma cells

A. Kuzikov, V. Shumyantseva, G. Morozevich, 2018, Russian Chemical Bulletin.

Synthesis of nitrogen-containing derivatives of 17(20)-pregnenoic, 17β-hydroxypregnanoic, and 17α-hydroxypregnanoic acids as new potential antiandrogens

M. Zavialova, R. Novikov, V. Timofeev, 2018, Russian Chemical Bulletin.

Simulation of EPR spectra of the radical TEMPO in water-lipid systems in different microwave ranges

V. Timofeev, A. Misharin, Y. Tkachev, 2011, Biofizika.

Nucleotide-induced and actin-induced structural changes in SH1-SH2-modified myosin subfragment 1

V. Timofeev, D. Levitsky, V. Mikhailova, 2007, Journal of Muscle Research and Cell Motility.

Lipophilic derivatives of natural chlorins: synthesis, mixed micelles with phospholipids, and uptake by cultured cells.

G. V. Ponomarev, M. Zavialova, V. Popenko, 2013, Bioorganic & medicinal chemistry.

Conjugates of Pyropheophorbide a with Androgen Receptor Ligands

G. V. Ponomarev, O. Koifman, M. Zavialova, 2017 .

Facile Synthesis of 15 2 -Carboxamides of Methyl Pheophorbide a

G. V. Ponomarev, M. Zavialova, N. O. Dugin, 2012 .

Natural Chlorins Modified with Cholesterol Moiety. Synthesis, Characteristics, Copper Complexes, and Entrapping in Phospholipid Vesicles

G. V. Ponomarev, M. Zavialova, R. Novikov, 2010 .

Fluorescence polarization and spin-label study of human myeloma immunoglobulins A and M. Presence of segmental flexibility.

E. Dudich, I. Dudich, V. Timofeev, 1980, Molecular immunology.

A spin label study of interaction of magnesium and ribulose 1,5-bisphosphate with ribulosebisphosphate carboxylase from spinach

I. Dudich, V. Timofeev, E. Mullokandov, 1982 .

Some peculiarities of the dynamics of the immunoglobulin M structure.

V. Timofeev, T. M. Kiseleva, V. A. Lapuk, 1984, Journal of biomolecular structure & dynamics.

Slow conformational change in anti‐dansyl antibody as a consequence of hapten binding

V. Timofeev, F. Franek, R.S. Nezlin, 1979, FEBS letters.

Spin‐label study of segmental flexibility of anti‐hapten antibodies

V. Timofeev, A. Misharin, F. Franek, 1979, FEBS letters.

Rotational correlation times of IgG and its fragments spin‐labeled at carbohydrate or protein moieties Spatially fixed position of the Fc carbohydrate

I. Dudich, V. Timofeev, Y. Sykulev, 1978, FEBS letters.

Spin-labeling of immunoglobulin carbohydrates.

V. Timofeev, Y. Sykulev, R. Nezlin, 1978, Immunochemistry.

[Macromolecule rotative correlation time measurement by ESR for covalently bound spin label].

M. V. Vol’kenshtein, I. Dudich, V. Timofeev, 1977, Molekuliarnaia biologiia.

Comparative study of dynamic structure of pig and chicken aspartate aminotransferases by measuring the rotational correlation time

M. Volkenstein, I. Dudich, V. Timofeev, 2004, Biophysics of structure and mechanism.

About New Universal Approach to the EPR-Spectra Simulation of the Spin-Labeled Macromolecules

V. Timofeev, B. Samarianov, 1993 .

Structural features of Fab fragments of rheumatoid factor IgM-RF in solution

V. Volkov, A. Sokolova, E. Shtykova, 2008 .

Accessibility of tryptophan residues in immunoglobulin M as an index of its conformational changeability.

V. Timofeev, E. Kaverzneva, V. A. Lapuk, 1990, Journal of biomolecular structure & dynamics.

Selective spin-labelling of N-acetylneuraminic acid residue in oligosaccharide of IgM Fab-region

V. Timofeev, T. M. Kiseleva, V. A. Lapuk, 1988 .

Selective spin-labelling of an N-acetylneuraminic acid residue in the Fab-region oligosaccharide of immunoglobulin M.

V. Timofeev, V. A. Lapuk, A. I. Tchukhrova, 1988, Immunology Letters.

About new universal approach to the EPR-spectra simulation of the spin-labeled macromolecules

V. Timofeev, B. Samarianov, 1993 .

An investigation of the segmental flexibility of spin labelled synthetic macromolecules in solutions

I. Dudich, V. Timofeev, A. Wasserman, 1981 .

Simple Analysis of ESR Spectra of Spin-Labelled Macromolecules with Account of Fast Anisotropic Rotation of a Spin-Label and Slow Diffusion Rotation of a Macromolecule

M. Volkenstein, I. Dudich, V. Timofeev, 1979 .

Dynamic spin label study of the barstar-barnase complex

V. Novikov, V. Timofeev, Y. Tkachev, 2007, Biochemistry (Moscow).

Intramolecular mobility of spin labelled poly(vinylpyrrolidone) and poly(vinylcaprolactam) in solutions

V. Timofeev, A. Shapiro, A. Wasserman, 1983 .

Conformational changes of aspartate aminotransferases in the region of Cys-45 residue observed by means of spin label.

M. Volkenstein, V. Timofeev, A. Misharin, 1973, Biochimica et biophysica acta.

Phase transitions of poly(octyl isocyanate): Simulation of the e.p.r. spectra of a dry spin-labelled polymer

H. Tenhu, V. Timofeev, J. Rantala, 1998 .

A comparative study of immunoglobulin IgM and rheumatoid factor IgMRF in solution by small-angle X-ray scattering

V. Volkov, E. Shtykova, V. Timofeev, 2012 .

Dynamics of macromolecule spin-labelled side-chain groups by electron paramagnetic resonance spectra simulation

V. Timofeev, B. Samarianov, 1995 .

Release of low molecular weight proteins from the Fc fragment of rabbit immunoglobulin G induced by formation of insoluble complexes with antigen.

E. Dudich, I. Dudich, V. Timofeev, 1983, Molecular Immunology.

Molecular mobility of spin-labelled terephthaloyl chloride and 1,10-decanediol copolymer in solution

F. Sundholm, A. Buchachenko, V. Timofeev, 1984 .

Application of spin‐labeled vitamin B6 analogues for the study of aspartate aminotransferase

V. Timofeev, A. Misharin, O. Polyanovsky, 1974, FEBS Letters.

Mobility of the paramagnetic label bound by aspartate aminotransferase.

M. Volkenstein, V. Timofeev, G. Lichtenstein, 1970, Biochimica et Biophysica Acta.

Solutions and gels of spin-labelled poly(octyl isocyanate) in non-polar hydrocarbon solvents

H. Tenhu, T. Turunen, V. Timofeev, 1995 .

Spin Label Method Reveals Barnase-Barstar Interaction: A Temperature and Viscosity Dependence Approach

V. Novikov, S. Deyev, A. Makarov, 2008, Journal of Biomolecular Structure and Dynamics.

The Role of the Fast Motion of the Spin Label in the Interpretation of EPR Spectra for Spin-Labeled Macromolecules

V. Timofeev, D. O. Nikolsky, 2003, Journal of biomolecular structure & dynamics.

Spin-labeled vitamin B6 derivatives: synthesis and interaction with aspartate aminotransferase.

V. Timofeev, A. Misharin, O. Polyanovsky, 1979, Methods in enzymology.

Regulation of cholesterol biosynthesis and metabolism in Hep G2 cells by Δ8(14)-15-ketoergostane derivatives

V. Timofeev, A. Misharin, A. R. Mehtiev, 2010, Biomeditsinskaia khimiia.

Oxidative C—O Cross-Coupling of 1,3-Dicarbonyl Compounds and Their Heteroanalogues with N-Substituted Hydroxamic Acids and N-Hydroxyimides.

A. Terent’ev, Z. Starikova, V. Timofeev, 2014 .

A simple synthesis of 3β-acetoxy-20-oxomethylpregn-5-ene and 3β-acetoxy-20-hydroxymethylpregn-5-ene

V. Timofeev, A. Misharin, F. Drozdov, 2006, Russian Journal of Bioorganic Chemistry.

Hydrogen bond contribution to the isotropic hyperfine splitting constant of a nitroxide free radical

G. Malenkov, V. Timofeev, A. V. Gagua, 1978 .

Cytotoxic derivatives of (22R,23R)-dihydroxystigmastane

G. Morozevich, V. Timofeev, A. Misharin, 2007, Russian journal of bioorganic chemistry.

Uniform EPR Spectra Analysis of Spin-Labeled Macromolecules by Temperature and Viscosity Dependences

V. Timofeev, Y. Tkachev, 2012 .

[A comparative structural analysis of Fab-fragments of monoclonal rheumatoid and non-rheumatoid immunoglobulins M].

V. Novikov, V. Timofeev, V. A. Lapuk, 2005, Biofizika.

Correlation between hematologic and biochemical parameters inTestudo horsfieldi

V. Timofeev, L. A. Tiunov, V. Ivanova, 1981, Bulletin of Experimental Biology and Medicine.

Stereoselective double lewis acid/organo-catalyzed dimerization of donor-acceptor cyclopropanes into substituted 2-oxabicyclo[3.3.0]octanes.

Yu. V. Tomilov, R. Novikov, V. Timofeev, 2012, The Journal of organic chemistry.