I. Aye

发表

Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors.

P. Mark, B. Waddell, J. Keelan, 2011, Placenta.

Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity.

P. Mark, B. Waddell, J. Keelan, 2010, Biochimica et biophysica acta.

Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth

F. Rosario, T. Powell, T. Jansson, 2015, Proceedings of the National Academy of Sciences.

Transport of lipids by ABC proteins: interactions and implications for cellular toxicity, viability and function.

J. Keelan, I. Aye, Ambika T. Singh, 2009, Chemico-biological interactions.

Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.

P. Mark, B. Waddell, J. Keelan, 2012, Molecular human reproduction.

Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis.

S. Weintraub, T. Powell, T. Jansson, 2014, Molecular endocrinology.

Inflammation in maternal obesity and gestational diabetes mellitus.

T. Powell, I. Aye, P. Pantham, 2015, Placenta.

Short Running Title : Regulation of adiponectin secretion in pregnancy

F. Rosario, T. Powell, T. Jansson, 2021 .

Review: Adiponectin--the missing link between maternal adiposity, placental transport and fetal growth?

T. Powell, T. Jansson, I. Aye, 2013, Placenta.

Insulin increases adipose adiponectin in pregnancy by inhibiting ubiquitination and degradation: Impact of obesity.

F. Rosario, T. Powell, T. Jansson, 2021, The Journal of clinical endocrinology and metabolism.

The Role of Placental Inflammasomes in Linking the Adverse Effects of Maternal Obesity on Fetal Development

T. Powell, I. Aye, S. Lager, 2015 .

Placental sex-dependent spermine synthesis regulates trophoblast gene expression through acetyl-coA metabolism and histone acetylation

A. Murray, A. Koulman, I. Aye, 2022, Communications Biology.

Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts

T. Powell, T. Jansson, I. Aye, 2013, Molecular and Cellular Endocrinology.

TNF-α stimulates System A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling

T. Powell, T. Jansson, I. Aye, 2015, Physiological reports.

Ceramide biosynthesis and metabolism in trophoblast syncytialization

J. Keelan, A. Dharmarajan, I. Aye, 2012, Molecular and Cellular Endocrinology.

Impact of Metformin Treatment on Human Placental Energy Production and Oxidative Stress

D. Charnock-Jones, C. Aiken, S. Ozanne, 2022, Frontiers in Cell and Developmental Biology.

The human placenta exhibits a unique transcriptomic void

D. Charnock-Jones, A. Lawson, Luke M. R. Harvey, 2022, bioRxiv.

IFPA Meeting 2010 Workshops Report II: Placental pathology; trophoblast invasion; fetal sex; parasites and the placenta; decidua and embryonic or fetal loss; trophoblast differentiation and syncytialisation.

C. Sibley, Á. Borbély, A. Jawerbaum, 2011, Placenta.

Expression and functional characterisation of System L amino acid transporters in the human term placenta

Y. Kanai, T. Powell, T. Jansson, 2015, Reproductive Biology and Endocrinology.

Labor inhibits placental mechanistic target of rapamycin complex 1 signaling.

T. Jansson, I. Aye, F. Gaccioli, 2014, Placenta.

Placental polyamines regulate acetyl-coA and histone acetylation in a sex-specific manner

D. Charnock-Jones, Gordon C. S. Smith, A. Murray, 2021, bioRxiv.

Placental polyamine metabolism differs by fetal sex, fetal growth restriction, and preeclampsia

A. Wood, D. Charnock-Jones, U. Sovio, 2018, JCI insight.

Screening for fetal growth restriction using fetal biometry combined with maternal biomarkers.

D. Charnock-Jones, U. Sovio, Gordon C. S. Smith, 2017, American journal of obstetrics and gynecology.

Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization.

J. Keelan, A. Dharmarajan, I. Aye, 2012, Reproductive biomedicine online.

Maternal group 2 innate lymphoid cells contribute to fetal growth and protection from endotoxin-induced abortion in mice

A. McKenzie, F. Colucci, R. Hamilton, 2018, bioRxiv.

Expression, localisation and activity of ATP binding cassette (ABC) family of drug transporters in human amnion membranes.

J. Keelan, D. Evseenko, J. Paxton, 2007, Placenta.

The emerging role of mTORC1 signaling in placental nutrient-sensing.

D. Goberdhan, T. Jansson, I. Aye, 2012, Placenta.

Placental energy metabolism in health and disease - significance of development and implications for preeclampsia.

D. Charnock-Jones, C. Aiken, Gordon C. S. Smith, 2020, American journal of obstetrics and gynecology.

Increasing Maternal Body Mass Index Is Associated with Systemic Inflammation in the Mother and the Activation of Distinct Placental Inflammatory Pathways1

Thomas Jansson, T. Powell, T. Jansson, 2014, Biology of reproduction.

Placental ABC transporters, cellular toxicity and stress in pregnancy.

J. Keelan, I. Aye, 2013, Chemico-biological interactions.

Reply to Carbillon: Fetal/placental weight ratio and placental function

F. Rosario, T. Powell, T. Jansson, 2016, Proceedings of the National Academy of Sciences.

Folate sensing by placental mtor signaling: A novel mechanism linking maternal folate levels, placental function and fetal development

F. Rosario, T. Powell, T. Jansson, 2015 .

Retosiban Prevents Stretch-Induced Human Myometrial Contractility and Delays Labor in Cynomolgus Monkeys

D. Charnock-Jones, I. Aye, D. Stanislaus, 2017, The Journal of clinical endocrinology and metabolism.

Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.

P. Mark, B. Waddell, J. Keelan, 2012, Molecular human reproduction.