J. Ficorilli

发表

A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity1

W. K. Wilson, K. Houck, K. Borchert, 2006, Journal of Lipid Research.

Novel Small Molecule Glucagon-like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and from Human Islets Running Title : Novel GLP-1 Receptor Small Molecule Agonist

F. Willard, K. Valasek, M. Michael, 2010 .

Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor.

C. Price, J. Keirns, D. Hauss, 1998, Journal of pharmaceutical sciences.

Intra-islet glucagon confers β-cell glucose competence for first-phase insulin secretion and favors GLP-1R stimulation by exogenous glucagon

O. Chepurny, G. Holz, C. Leech, 2021, The Journal of biological chemistry.

Farnesoid X Receptor Agonist Reduces Serum Asymmetric Dimethylarginine Levels through Hepatic Dimethylarginine Dimethylaminohydrolase-1 Gene Regulation*

S. Li, M. Michael, J. Ficorilli, 2006, Journal of Biological Chemistry.

Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5

F. Willard, T. Suter, M. Statnick, 2017, Endocrinology.

for Drug Discovery □ S

P. Sexton, A. Christopoulos, L. May, 2012 .

β-Cell Glucagon-Like Peptide-1 Receptor Contributes to Improved Glucose Tolerance After Vertical Sleeve Gastrectomy.

B. Cummings, M. Michael, K. Sloop, 2016, Endocrinology.

A Novel Humanized GLP-1 Receptor Model Enables Both Affinity Purification and Cre-LoxP Deletion of the Receptor

F. Dai, M. Wheeler, T. Coşkun, 2014, PloS one.

Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the TRPA1 channel

A. Efanov, J. Ficorilli, S. Syed, 2018 .

Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion.

K. Bokvist, L. Beavers, Thomas B. Farb, 2013, American journal of physiology. Endocrinology and metabolism.

Ectonucleotidase NTPDase 3 is abundant in pancreatic β cells and regulates 1 glucose induced insulin secretion

K. Bokvist, L. Beavers, Thomas B. Farb, 2013 .

MDL 101,002, a free radical spin trap, is efficacious in permanent and transient focal ischemia models.

H. Cheng, J. Ficorilli, M. P. Johnson, 1998, Life sciences.

679-P: The Novel GIP, GLP-1, and Glucagon Triple Receptor Agonist LY3437943 Exhibits Robust Efficacy in Preclinical Models of Obesity and Diabetes

F. Willard, Hongchang Qu, T. Coşkun, 2021, Diabetes.

Structure-based design of potent, amidine-derived inhibitors of factor Xa: evaluation of selectivity, anticoagulant activity, and antithrombotic activity.

J. A. Kyle, N. Chirgadze, S. Briggs, 2000, Journal of Medicinal Chemistry.

Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles*

F. Willard, A. D. Showalter, K. Sloop, 2016, The Journal of Biological Chemistry.

Inhibition of Deoxyhypusine Synthase Enhances Islet β Cell Function and Survival in the Setting of Endoplasmic Reticulum Stress and Type 2 Diabetes*

B. Maier, S. Tersey, R. Mirmira, 2010, The Journal of Biological Chemistry.

Chronic Collection of Mesenteric Lymph From Conscious, Tethered Rats.

D. Hauss, J. Ficorilli, S. Fogal, 1998, Contemporary topics in laboratory animal science.

Allosteric Modulation of Endogenous Metabolites as an Avenue for Drug Discovery

P. Sexton, A. Christopoulos, L. May, 2012, Molecular Pharmacology.

Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets

Francis S. Willard, F. Willard, M. Michael, 2010, Diabetes.

Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the transient receptor potential A1 (TRPA1) channel

A. Obukhov, A. Efanov, J. Ficorilli, 2018, The Journal of Biological Chemistry.

Hepatic peroxisomal fatty acid β-oxidation is regulated by liver X receptor α

Angela M. Siesky, S. Li, M. Michael, 2005 .

Hepatic peroxisomal fatty acid beta-oxidation is regulated by liver X receptor alpha.

Angela M. Siesky, S. Li, M. Michael, 2005, Endocrinology.

Regulation of carbohydrate metabolism by the farnesoid X receptor.

R. Savkur, K. Bramlett, T. Burris, 2005, Endocrinology.

Structural insights into probe-dependent positive allosterism of the GLP-1 receptor

M. Vieth, B. Chau, T. S. Kobilka, 2020, Nature Chemical Biology.

The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470).

C. Hamdouchi, C. Montrose‐Rafizadeh, R. Belin, 2016, Journal of medicinal chemistry.

Small Molecule Allosteric Modulation of the Glucagon-Like Peptide-1 Receptor Enhances the Insulinotropic Effect of Oxyntomodulin

P. Sexton, A. Christopoulos, F. Willard, 2012, Molecular Pharmacology.

Regulation of GPR119 receptor activity with endocannabinoid-like lipids.

K. Bokvist, M. Kuo, H. Bui, 2012, American journal of physiology. Endocrinology and metabolism.

Small Molecule Allosteric Modulation of the Glucagon-Like Peptide-1 Receptor Enhances the Insulinotropic Effect of Oxyntomodulin

P. Sexton, A. Christopoulos, F. Willard, 2012, Molecular Pharmacology.

Structure-based design of potent, amidine-derived inhibitors of factor Xa: evaluation of selectivity, anticoagulant activity, and antithrombotic activity.

J. A. Kyle, Michael Robert Wiley, N. Chirgadze, 2000, Journal of Medicinal Chemistry.

Allosteric modulation of endogenous metabolites as an avenue for drug discovery

P. Sexton, A. Christopoulos, L. May, 2012 .