D. Wiggins

发表

Inhibition of cholesterol absorption associated with a PPAR alpha-dependent increase in ABC binding cassette transporter A1 in mice.

G. Gibbons, S. Humphreys, B. Knight, 2003, Journal of lipid research.

Studies on the mechanism of the antifungal action of benzoate.

A. Sols, H. Krebs, M. Stubbs, 1983, The Biochemical journal.

The enzymology of hepatic very-low-density lipoprotein assembly.

G. Gibbons, D. Wiggins, 1995, Biochemical Society transactions.

Origin of hepatic very-low-density lipoprotein triacylglycerol: the contribution of cellular phospholipid.

G. Gibbons, D. Wiggins, Geoffrey F. Gibbons, 1996, The Biochemical journal.

PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery

P. Rorsman, L. McCulloch, A. Clark, 2016, Cell reports.

Comparative effects of tumour necrosis factor-alpha (cachectin), interleukin-1-beta and tumour growth on amino acid metabolism in the rat in vivo. Absorption and tissue uptake of alpha-amino[1-14C]isobutyrate.

F. López‐Soriano, J. M. Argiles, D. Williamson, 1989, The Biochemical journal.

Chronic exogenous hyperinsulinaemia does not modify the acute inhibitory effect of insulin on the secretion of very-low-density lipoprotein triacylglycerol and apolipoprotein B in primary cultures of rat hepatocytes.

G. Gibbons, D. Wiggins, C. Bourgeois, 1996, The Biochemical journal.

The roles of insulin and fatty acids in the regulation of hepatic very-low-density lipoprotein assembly.

R. Pease, G. Gibbons, D. Wiggins, 2002, Journal of the Royal Society of Medicine.

The matrix water space of mitochondriain situ in isolated hepatocytes

P. Lund, D. Wiggins, 1987, Bioscience reports.

Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice Published, JLR Papers in Press, August 1, 2003. DOI 10.1194/jlr.M300042-JLR200

G. Gibbons, S. Humphreys, B. Knight, 2003, Journal of Lipid Research.

Peroxisome Proliferator-activated Receptor α Deficiency Abolishes the Response of Lipogenic Gene Expression to Re-feeding

G. Gibbons, B. Knight, D. Patel, 2008, Journal of Biological Chemistry.

Characterization of lipoprotein composition in rats fed different dietary lipids and of the effects of lipoproteins upon lymphocyte proliferation

P. Calder, E. Newsholme, P. Yaqoob, 1996 .

Manipulation of cholesterol and cholesteryl ester synthesis has multiple effects on the metabolism of apolipoprotein B and the secretion of very-low-density lipoprotein by primary hepatocyte cultures.

G. Gibbons, D. Wiggins, A. Brown, 1999, Biochimica et biophysica acta.

Phosphorylation of adenosine monophosphate in the mitochondrial matrix.

H. Krebs, D. Wiggins, 1978, The Biochemical journal.

Metabolic characteristics of a human hepatoma cell line stably transfected with hormone-sensitive lipase.

R. Pease, J. Tree, G. Gibbons, 1999, The Biochemical journal.

Specialized hepatocyte-like cells regulate Drosophila lipid metabolism

B. Fielding, A. Gould, D. Wiggins, 2007, Nature.

Adaptation of urate synthesis in chicken liver.

H. Krebs, P. Lund, D. Wiggins, 1982, Comparative biochemistry and physiology. B, Comparative biochemistry.

Maintenance of energy-linked functions in rat liver mitochondria.

P. Lund, D. Wiggins, 1990, Biochimica et biophysica acta.

Chelating agents and rat liver mitochondria.

P. Lund, D. Wiggins, 1989, Biochimica et biophysica acta.

The effect of temperature of glutamine containing TPN mixtures

G. Hardy, D. Wiggins, G. Grimble, 1992 .

A dominant negative human peroxisome proliferator-activated receptor (PPAR){alpha} is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms.

V K K Chatterjee, S. O’Rahilly, A. Meirhaeghe, 2005, Endocrinology.

The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas.

G. Gibbons, D. Wiggins, D Wiggins, 1992, The Biochemical journal.

Selective recruitment of ApoB-48 for the assembly of VLDL in rat triacylglycerol-enriched hepatocytes.

G. Gibbons, D. Wiggins, P. Coussons, 1996, Arteriosclerosis, thrombosis, and vascular biology.

The effect of cysteine oxidation on isolated hepatocytes.

H. Krebs, J. Viña, G. Sáez, 1983, The Biochemical journal.

A role for PPARalpha in the control of SREBP activity and lipid synthesis in the liver.

G. Gibbons, D. Hauton, B. Knight, 2005, The Biochemical journal.

Synthesis and function of hepatic very-low-density lipoprotein.

G. Gibbons, D. Wiggins, A. Brown, 2004, Biochemical Society transactions.

Intracellular triacylglycerol lipase: its role in the assembly of hepatic very-low-density lipoprotein (VLDL).

G. Gibbons, D. Wiggins, 1995, Advances in enzyme regulation.

Preservation of hepatocyte suspensions at 4 degrees C.

P. Lund, D. Wiggins, 1988, Transplantation.

Co-ordination of hepatic and adipose tissue lipid metabolism after oral glucose.

J. Bülow, K. Frayn, L. Simonsen, 1999, Journal of lipid research.

Disturbances in the normal regulation of SREBP-sensitive genes in PPARα-deficient mice

G. Gibbons, S. Humphreys, B. Knight, 2001 .

The functional efficiency of lipogenic and cholesterogenic gene expression in normal mice and in mice lacking the peroxisomal proliferator-activated receptor-alpha (PPAR-alpha).

G. Gibbons, B. Knight, D. Wiggins, 2002, Advances in enzyme regulation.

Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice.

G. Gibbons, S. Humphreys, B. Knight, 2001, Journal of lipid research.

VLDL output by hepatocytes from obese Zucker rats is resistant to the inhibitory effect of insulin.

G. Gibbons, R. Hems, D. Wiggins, 1995, The American journal of physiology.

Decreased sensitivity to the inhibitory effect of insulin on the secretion of very-low-density lipoprotein in cultured hepatocytes from fructose-fed rats.

G. Gibbons, R. Hems, D. Wiggins, 1995, Metabolism: clinical and experimental.

Complications in the use of albumin: contamination with copper and calcium.

B. Buckley, P. Lund, D. Wiggins, 1988, Contributions to Nephrology.

Is N-acetylglutamate a short-term regulator of urea synthesis?

P. Lund, D. Wiggins, 1984, The Biochemical journal.

Amino acid profiles during development of the fetal rat.

P. Lund, D. Wiggins, J. Hislop, 1987, Biology of the neonate.

Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis

C. Lelliott, S. O’Rahilly, M. Jimenez-Linan, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of carbamoyl-phosphate synthase (ammonia) by Tris and Hepes. Effect on Ka for N-acetylglutamate.

P. Lund, D. Wiggins, 1987, The Biochemical journal.

The ornithine requirement of urea synthesis. Formation of ornithine from glutamine in hepatocytes.

P. Lund, D. Wiggins, 1986, The Biochemical journal.

Inhibition of Hepatocyte Lipogenesis by Nitric Oxide Donor: Could Nitric Oxide Regulate Lipid Synthesis?

G. Gibbons, R. Hems, W. Roediger, 2004, IUBMB life.

The intracellular triacylglycerol/fatty acid cycle: a comparison of its activity in hepatocytes which secrete exclusively apolipoprotein (apo) B100 very-low-density lipoprotein (VLDL) and in those which secrete predominantly apoB48 VLDL.

A. Salter, G. Gibbons, D. Wiggins, 1998, The Biochemical journal.

Glucose phosphorylation is essential for the turnover of neutral lipid and the second stage assembly of triacylglycerol-rich ApoB-containing lipoproteins in primary hepatocyte cultures.

G. Gibbons, D. Wiggins, A. Brown, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Hepatocyte Cultures Stage Assembly of Triacylglycerol-Rich ApoB-Containing Lipoproteins in Primary Glucose Phosphorylation Is Essential for the Turnover of Neutral Lipid and the Second Print

G. Gibbons, D. Wiggins, 1999 .

Peroxisome proliferator-activated receptor alpha deficiency abolishes the response of lipogenic gene expression to re-feeding: restoration of the normal response by activation of liver X receptor alpha.

G. Gibbons, B. Knight, D. Patel, 2008, The Journal of biological chemistry.

Scintillation counting and vinyl gloves

P. Lund, D. Wiggins, 1983 .