C. Einarsson

发表

Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.

L. Bertilsson, L. Bretillon, U. Diczfalusy, 2001, The Journal of biological chemistry.

Effects of combined treatment with pravastatin and ursodeoxycholic acid on hepatic cholesterol metabolism

S. Sahlin, B. Nyberg, M. Rudling, 2002, European journal of clinical investigation.

Increased NPC1L1 and ACAT2 expression in the jejunal mucosa from Chinese gallstone patients.

M. Eriksson, Zhao-yan Jiang, P. Parini, 2009, Biochemical and biophysical research communications.

Critical role of cholic acid for development of hypercholesterolemia and gallstones in diabetic mice.

M. Rudling, I. Björkhem, C. Einarsson, 2006, Biochemical and biophysical research communications.

Bile acids and lipoprotein metabolism: effects of cholestyramine and chenodeoxycholic acid on human hepatic mRNA expression.

S. Sahlin, B. Angelin, P. Parini, 2007, Biochemical and biophysical research communications.

The Peroxisome Proliferator-activated Receptor α (PPARα) Regulates Bile Acid Biosynthesis*

M. Hunt, S. Alexson, C. Einarsson, 2000, The Journal of Biological Chemistry.

Increased expression of LXRα, ABCG5, ABCG8, and SR-BI in the liver from normolipidemic, nonobese Chinese gallstone patients Published, JLR Papers in Press, November 15, 2007.

Hai Hu, Matt Davis, L. Rudel, 2008, Journal of Lipid Research.

Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity

M. Trauner, T. Stojaković, A. Thorell, 2015, Journal of hepatology.

Characterization of enzymes involved in formation of ethyl esters of long-chain fatty acids in humans.

I. Björkhem, S. Alexson, C. Einarsson, 2001, Journal of lipid research.

Gallbladder bile composition in patients with Crohn 's disease.

C. Einarsson, J. Åkerlund, A. Lapidus, 2006, World journal of gastroenterology.

Feedback regulation of bile acid synthesis in human liver: importance of HNF-4alpha for regulation of CYP7A1.

S. Sahlin, I. Björkhem, E. Ellis, 2005, Biochemical and biophysical research communications.

Cholesterol Synthesis Inhibition Elicits an Integrated Molecular Response in Human Livers Including Decreased ACAT2

S. Ōmura, M. Eriksson, S. Sahlin, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Regulation of hepatic low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and cholesterol 7alpha-hydroxylase mRNAs in human liver.

S. Sahlin, B. Angelin, M. Rudling, 2002, The Journal of clinical endocrinology and metabolism.

GH is a regulator of IGF2 promoter-specific transcription in human liver.

T. Ekström, M. Tally, H. Olivecrona, 2002, The Journal of endocrinology.

Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor.

G. Nowak, I. Björkhem, E. Ellis, 2003, Hepatology.

Feedback regulation of bile acid synthesis in primary human hepatocytes: Evidence that CDCA is the strongest inhibitor

G. Nowak, I. Björkhem, E. Ellis, 2003, Hepatology.

Thyroid hormone suppresses hepatic sterol 12alpha-hydroxylase (CYP8B1) activity and messenger ribonucleic acid in rat liver: failure to define known thyroid hormone response elements in the gene.

I. Björkhem, C. Einarsson, G. Eggertsen, 1999, Biochimica et biophysica acta.

Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis

J. Gustafsson, I. Talianidis, E. Treuter, 2007, Proceedings of the National Academy of Sciences.

Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12alpha-hydroxylase gene (CYP8B1).

J. Chiang, I. Björkhem, C. Einarsson, 2004, Biochemical and biophysical research communications.

Ethanol stimulates bile acid formation in primary human hepatocytes.

S. Strom, E. Ellis, G. Nowak, 2007, Biochemical and biophysical research communications.

Bile acid synthesis is increased in Chilean Hispanics with gallstones and in gallstone high-risk Mapuche Indians.

J. Miquel, F. Nervi, M. Rudling, 2004, Gastroenterology.

Differential hepatocellular zonation pattern of cholesterol 7α-hydroxylase (Cyp7a1) and sterol 12α-hydroxylase (Cyp8b1) in the mouse

I. Björkhem, B. Rozell, M. Olin, 2007, Histochemistry and Cell Biology.

Human sterol 12α-hydroxylase (CYP8B1) is mainly expressed in hepatocytes in a homogenous pattern

B. Rozell, E. Reihnér, C. Einarsson, 2005, Histochemistry and Cell Biology.

Differences in the Regulation of the Classical and the Alternative Pathway for Bile Acid Synthesis in Human Liver

B. Angelin, M. Rudling, I. Björkhem, 2002, The Journal of Biological Chemistry.

High level of deoxycholic acid in human bile does not promote cholesterol gallstone formation.

S. Sahlin, C. Einarsson, U. Gustafsson, 2003, World journal of gastroenterology.

Biliary lipid composition in patients with cholesterol and pigment gallstones and gallstone‐free subjects: deoxycholic acid does not contribute to formation of cholesterol gallstones

S. Sahlin, C. Einarsson, U. Gustafsson, 2000, European journal of clinical investigation.

Effects of colectomy on bile composition, cholesterol saturation and cholesterol crystal formation in humans

C. Einarsson, J. Åkerlund, 2000, International Journal of Colorectal Disease.

Deoxycholic acid treatment in patients with cholesterol gallstones: failure to detect a suppression of cholesterol 7α‐hydroxylase activity

B. Nyberg, B. Angelin, M. Rudling, 1999, Journal of internal medicine.

Effects of treatment with deoxycholic acid and chenodeoxycholic acid on the hepatic synthesis of cholesterol and bile acids in healthy subjects

C. Einarsson, C. Hillebrant, M. Axelson, 2001, Hepatology.

Bile acid formation in primary human hepatocytes.

E. Ellis, B. Ericzon, C. Einarsson, 2000, World journal of gastroenterology.

Bile acid synthesis in primary cultures of rat and human hepatocytes

M. Rudling, A. Mode, I. Björkhem, 1998, Hepatology.

Changes in gallbladder bile composition and crystal detection time in morbidly obese subjects after bariatric surgery

S. Sahlin, A. Groen, C. Einarsson, 2005, Hepatology.

The genetic background of gallstone formation: an update.

M. Rudling, H. Marschall, C. Einarsson, 2010, Biochemical and Biophysical Research Communications - BBRC.

Polymorphism in the coding part of the sterol 12α‐hydroxylase gene does not explain the marked differences in the ratio of cholic acid and chenodeoxycholic acid in human bile

I. Björkhem, E. Reihnér, C. Einarsson, 2005, Scandinavian journal of clinical and laboratory investigation.

From Brain to Bile

L. Ellegård, I. Björkhem, U. Diczfalusy, 2001, The Journal of Biological Chemistry.

Successful treatment of severe unconjugated hyperbilirubinemia via induction of UGT1A1 by rifampicin.

C. Strassburg, F. Lammert, M. Trauner, 2006, Journal of hepatology.

Analysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorption.

P. Dawson, H. Marschall, M. Montagnani, 2006, World journal of gastroenterology.

ACAT2 and human hepatic cholesterol metabolism: identification of important gender-related differences in normolipidemic, non-obese Chinese patients.

M. Eriksson, L. Rudel, Zhao-yan Jiang, 2009, Atherosclerosis.

From Brain to Bile EVIDENCE THAT CONJUGATION AND (cid:1) -HYDROXYLATION ARE IMPORTANT FOR ELIMINATION OF 24S-HYDROXYCHOLESTEROL (CEREBROSTEROL) IN HUMANS*

L. Ellegård, I. Björkhem, U. Diczfalusy, 2001 .

6 Genetic and environmental influences for gallstone disease-related diagnoses: A Swedish twin study of 43,141 twin pairs

F. Lammert, P. Lichtenstein, A. Grjibovski, 2004 .

Common polymorphisms in the CYP7A1 gene do not contribute to variation in rates of bile acid synthesis and plasma LDL cholesterol concentration.

F. V. van’t Hooft, M. Ingelman-Sundberg, B. Angelin, 2005, Atherosclerosis.

Genetic and environmental influences on symptomatic gallstone disease: A Swedish study of 43,141 twin pairs

F. Lammert, P. Lichtenstein, A. Grjibovski, 2005, Hepatology.

Bile acid synthesis in cultured human hepatocytes: support for an alternative biosynthetic pathway to cholic acid

I. Björkhem, E. Ellis, B. Ericzon, 2000, Hepatology.

Bile Composition in Patients with Ileal Resection Due to Crohn's Disease

C. Einarsson, A. Lapidus, Curt Einarsson, 1998, Inflammatory bowel diseases.

Ecological aspects of antimicrobial treatment ofHelicobacter pylori infections

C. Nord, C. Einarsson, 1997, Infection.

Isoursodeoxycholic acid: metabolism and therapeutic effects in primary biliary cirrhosis.

S. Matern, H. Marschall, G. Alvélius, 2001, Journal of lipid research.

Microsomal long-chain acyl-CoA thioesterase (carboxylesterase ES-4) is regulated by thyroxine.

I. Björkhem, S. Alexson, C. Einarsson, 1999, Biochimica et biophysica acta.

The micro-flora of the small bowel in health and disease.

H. Törnblom, G. Lindberg, C. Nord, 2003, Anaerobe.

Gallstone disease

H. Marschall, C. Einarsson, 2007, Journal of internal medicine.

ACAT2 Is Localized to Hepatocytes and Is the Major Cholesterol-Esterifying Enzyme in Human Liver

Mats Eriksson, Hiroshi Tomoda, Satoshi Omura, 2004, Circulation.

DNA ploidy and S-phase fraction in carcinoma of the gallbladder related to histopathology, number of gallstones and survival

S. Sahlin, V. Gadaleanu, B. Tribukait, 2014 .

Ursodeoxycholic acid treatment in IBD-patients with colorectal dysplasia and/or DNA-aneuploidy: a prospective, double-blind, randomized controlled pilot study.

R. Löfberg, A. Ost, B. Tribukait, 2004, Anticancer research.

Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.

S. Sahlin, M. Trauner, H. Marschall, 2005, Gastroenterology.

Body mass index, alcohol, tobacco and symptomatic gallstone disease: a Swedish twin study

P. Lichtenstein, C. Tuvblad, C. Einarsson, 2007, Journal of internal medicine.

DNA Ploidy and S-Phase Fraction in Carcinoma of the Gallbladder Related to Histopathology, Number of Gallstones and Survival 1

S. Sahlin, V. Gadaleanu, B. Tribukait, 2001, Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology.

Formation of fatty acid ethyl esters in rat liver microsomes. Evidence for a key role for acyl-CoA: ethanol O-acyltransferase.

I. Björkhem, S. Alexson, C. Einarsson, 1999, European journal of biochemistry.

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

H. Melhus, P. Artursson, H. Törnblom, 2001, The Journal of pharmacology and experimental therapeutics.

Studies on the mechanism of accumulation of cholesterol in the gallbladder mucosa. Evidence that sterol 27-hydroxylase is not a pathogenetic factor.

S. Sahlin, I. Björkhem, S. Bringman, 2004, Journal of hepatology.

Bouveret's syndrome followed by gallstone entrapment in the stomach: an uncommon cause of upper gastrointestinal bleeding and gastric retention.

C. Einarsson, E. Kullman, K. Borch, 2000, The European journal of surgery = Acta chirurgica.

Ursodeoxycholic acid increased bile flow and affects bile composition in the early postoperative phase following liver transplantation

B. Ericzon, G. Nowak, G. Söderdahl, 1998, Transplant international : official journal of the European Society for Organ Transplantation.

The level of 7-dehydrocholesterol in plasma reflects the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the human liver.

B. Angelin, E. Reihnér, C. Einarsson, 1998, Biochimica et biophysica acta.

define the group of patients who would benefit from combination of ursodeoxycholic acid and rifampicin.

S. Sahlin, M. Tobi, J. Dingell, 2006 .

The peroxisome proliferator-activated receptor alpha (PPARalpha) regulates bile acid biosynthesis.

M. Hunt, S. Alexson, C. Einarsson, 2000, The Journal of biological chemistry.

Gallstone disease in Swedish twins: risk is associated with ABCG8 D19H genotype

P. Lichtenstein, P. Magnusson, M. Krawczyk, 2010, Journal of internal medicine.

Antiepileptic Drugs Increase Plasma Levels of 4β-Hydroxycholesterolin Humans

L. Bertilsson, L. Bretillon, U. Diczfalusy, 2001, The Journal of Biological Chemistry.

303 Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients

S. Sahlin, M. Trauner, H. Marschall, 2004 .

Hypocholesterolemic effects of fatty acid bile acid conjugates (FABACs) in mice.

P. Parini, A. Leikin-Frenkel, F. Konikoff, 2008, Archives of biochemistry and biophysics.

Gallstone disease

H. Marschall, C. Einarsson, 2007, Journal of internal medicine.

Studies on LXR- and FXR-mediated effects on cholesterol homeostasis in normal and cholic acid-depleted mice Published, JLR Papers in Press, November 1, 2005.

P. Parini, I. Björkhem, C. Einarsson, 2006, Journal of Lipid Research.

Increased expression of LXR a , ABCG 5 , ABCG 8 , and SR-BI in the liver from normolipidemic , nonobese Chinese gallstone patients

Hai Hu, Matt Davis, L. Rudel, 2008 .

Gallstone disease in Swedish twins is associated with the Gilbert variant of UGT1A1

F. Lammert, M. Krawczyk, H. Marschall, 2013, Liver international : official journal of the International Association for the Study of the Liver.

Differential hepatocellular zonation pattern of cholesterol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) in the mouse.

I. Björkhem, B. Rozell, M. Olin, 2007, Histochemistry and cell biology.