R. Syhre

发表

Radiochemical synthesis and tissue distribution of Tc-99m-labeled 7alpha-substituted estradiol complexes.

M. Welch, J. Katzenellenbogen, H. Spies, 2000, Nuclear medicine and biology.

Novel tumortropic ester derivatives of 99mTc(V) mesodimercapto succinic acid with low affinity for bone tissue

H. Spies, B. Johannsen, R. Syhre, 2003, Nuclear medicine communications.

Synthesis, biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high affinity for the 5-HT(1A) receptor and the alpha1-adrenergic receptor.

P. Brust, C. Halldin, K. Varnäs, 2002, Nuclear medicine and biology.

Chemical and biological characterization of technetium(I) and Rhenium(I) tricarbonyl complexes with dithioether ligands serving as linkers for coupling the Tc(CO)(3) and Re(CO)(3) moieties to biologically active molecules.

H. Spies, B. Johannsen, P. Schubiger, 2000, Bioconjugate chemistry.

Synthesis and autoradiographic evaluation of a novel high-affinity Tc-99m ligand for the 5-HT2A receptor.

M. Scheunemann, P. Brust, H. Spies, 1999, Nuclear Medicine and Biology.

A novel technetium-99m radioligand for the 5-HT1A receptor derived from desmethyl-WAY-100635 (DWAY)

B. Johannsen, H. Pietzsch, R. Syhre, 2001, European Journal of Nuclear Medicine and Molecular Imaging.

No carrier added preparations of ‘3 + 1’ mixed-ligand 99mTc complexes

M. Scheunemann, H. Spies, B. Johannsen, 1998 .

Technetium(V) and rhenium(V) complexes for 5-HT2A serotonin receptor binding: structure-affinity considerations.

M. Scheunemann, P. Brust, H. Spies, 1996, Nuclear medicine and biology.

Dramatic effect of the tridentate ligand on the stability of 99mTC "3 + 1" oxo complexes bearing arylpiperazine derivatives.

J. Correia, R. Bergmann, H. Spies, 2005, Bioconjugate chemistry.

Stability versus reactivity of ”3+1” mixed-ligand technetium-99m complexes in vitro and in vivo

H. Spies, B. Johannsen, R. Syhre, 1998, European Journal of Nuclear Medicine.

Tc and Re chelates of 8alpha-amino-6-methyl-ergoline: synthesis and affinity to the dopamine D2 receptor.

P. Brust, H. Spies, M. Findeisen, 2002, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of technetium(III) mixed-ligand complexes with high affinity for the cerebral 5-HT(1A) receptor and the alpha1-adrenergic receptor.

C. Halldin, K. Varnäs, H. Hall, 2002, Nuclear medicine and biology.

Ligand-exchange reaction of labile "3 + 1"99mTc(V) complexes with SH group-containing proteins.

H. Spies, B. Johannsen, R. Syhre, 2001, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Reactivity of 99mTc(V) ''3+1''mixed-ligand complexes towards glutathione

M. Scheunemann, P. Brust, B. Johannsen, 2001 .

Structural modification of receptor-binding technetium-99m complexes in order to improve brain uptake

M. Scheunemann, P. Brust, H. Spies, 1997, European Journal of Nuclear Medicine.

Mixed-ligand technetium(III) complexes with tetradendate/monodendate NS(3)/isocyanide coordination: a new nonpolar technetium chelate system for the design of neutral and lipophilic complexes stable in vivo.

H. Spies, H. Pietzsch, R. Syhre, 2001, Bioconjugate chemistry.

Synthesis, characterization, and biological evaluation of technetium(III) complexes with tridentate/bidentate S,E,S/P,S coordination (E = O, N(CH(3)), S): a novel approach to robust technetium chelates suitable for linking the metal to biomolecules.

H. Spies, F. Tisato, H. Pietzsch, 2003, Bioconjugate chemistry.