Baihua Hu

发表

Quinoline-3-carboxamide containing sulfones as liver X receptor (LXR) agonists with binding selectivity for LXRbeta and low blood-brain penetration.

Anna Wilhelmsson, P. Nambi, M. Evans, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors.

K. Fan, R. Chopra, J. Ellingboe, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 2-carboxylic acid indoles as inhibitors of plasminogen activator inhibitor-1.

J. Bauer, L. Di, Baihua Hu, 2005, Bioorganic & medicinal chemistry letters.

Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.

J. D. Clark, M. Hegen, J. McKew, 2008, Journal of medicinal chemistry.

Synthesis of Conformationally-Constrained Glutamate Analogues of the Antitumor Agents DDATHF, LY254155, and LY231514

Baihua Hu, J. Jun, P. Zhou, 1997 .

Synthesis of Some Conformationally-constrained Glutamate Mimics of N-{5-[2-amino-3,4-dihydro-4-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine-6-yl)ethyl]thien-2-ylcarbonyl-L-glutamic Acid (LY254155)

Baihua Hu, E. Taylor, 1997 .

Further modification on phenyl acetic acid based quinolines as liver X receptor modulators.

Farooq Azam, Anna Wilhelmsson, James Jetter, 2007, Bioorganic & medicinal chemistry.

Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis.

Christopher Miller, Farooq Azam, Anna Wilhelmsson, 2006, Journal of medicinal chemistry.

Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRbeta.

P. Nambi, Baihua Hu, Raymound Unwalla, 2009, Bioorganic & medicinal chemistry.

Synthesis of heterocycle substituted 1-aryl-4-piperidones

M. Malamas, J. Ellingboe, Baihua Hu, 2002 .

Novel synthesis of a conformationally-constrained analog of DDATHF

Edward C. Taylor, Baihua Hu, Ping Zhou, 1997 .

Synthesis of Heterocycle-Substituted 1-Aryl-4-piperidones.

M. Malamas, J. Ellingboe, Baihua Hu, 2003 .

Highly stereoselective [3 + 2] annulations by cyclopropanation of vinyl ethers with rhodium(II)-stabilized vinylcarbenoids followed by a formally forbidden 1,3-sigmatropic rearrangement

H. Davies, Baihua Hu, 1992 .

Comments on an Attempted Synthesis of 1-Aminocyclopropane-1,2-Dicarboxylic Acid

Baihua Hu, E. Taylor, 1996 .

Ring expansion of tert-butyl 1-vinylcyclopropane-1-carboxylates to .alpha.-ethylidenebutyrolactones

H. Davies, Baihua Hu, 1992 .

Divergent reaction pathways between rhodium(II)-stabilized vinylcarbenoids and benzenes

H. Davies, Baihua Hu, H. D. Smith, 1992 .

Synthesis and structure-activity relationship of alpha-sulfonylhydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis.

John Ellingboe, J. Skotnicki, J. Ellingboe, 2003, Journal of medicinal chemistry.

New Oxadiazolidinedione Derivatives as Potent and Selective Human β3 Agonists.

M. Malamas, R. Mulvey, J. Ellingboe, 2001 .

Synthesis of Conformationally‐Constrained Glutamate Analogues of the Antitumor Agents DDATHF, LY254155, and LY231514.

Baihua Hu, J. Jun, P. Zhou, 1997 .

Synthesis of Some Conformationally‐Constrained Glutamate Mimics of N‐( 5‐(2‐(2‐Amino‐3,4‐dihydro‐4‐oxo‐5,6,7,8‐tetrahydropyrido(2,3‐d) pyrimidin‐6‐yl)ethyl)thien‐2‐ylcarbonyl)‐L‐glutamic Acid (LY254155).

Baihua Hu, E. Taylor, 1997 .

Orally Bioavailable β3-Adrenergic Receptor Agonists as Potential Therapeutic Agents for Obesityand Type-II Diabetes

Baihua Hu, Lee L Jennings, 2003 .

Identification of phenylsulfone-substituted quinoxaline (WYE-672) as a tissue selective liver X-receptor (LXR) agonist.

Anna Wilhelmsson, M. Evans, Baihua Hu, 2010, Journal of medicinal chemistry.

Structure-Based Approach To Identify 5-[4-Hydroxyphenyl]pyrrole-2-carbonitrile Derivatives as Potent and Tissue Selective Androgen Receptor Modulators.

K. Parris, D. Powell, S. Nagpal, 2017, Journal of medicinal chemistry.

Highly Stereoselective (3 + 2)Annulations by Cyclopropanation of Vinyl Ethers with Rhodium(II)-Stabilized Vinylcarbenoids Followed by a Formally Forbidden 1,3-Sigmatropic Rearrangement.

H. Davies, Baihua Hu, 1992 .

Orally bioavailable beta 3-adrenergic receptor agonists as potential therapeutic agents for obesity and type-II diabetes.

Baihua Hu, Lee L Jennings, 2003, Progress in medicinal chemistry.

Novel (4-piperidin-1-yl)-phenyl sulfonamides as potent and selective human beta(3) agonists.

M. Malamas, R. Mulvey, A. Oliphant, 2001, Bioorganic & medicinal chemistry.

Carboxylic acid based quinolines as liver X receptor modulators that have LXRbeta receptor binding selectivity.

Lisa Nogle, Anna Wilhelmsson, James Jetter, 2008, Bioorganic & medicinal chemistry letters.

Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors.

M. Malamas, K. Fan, A. Robichaud, 2010, Bioorganic & medicinal chemistry letters.