A. Goos-Nilsson

发表

Quinoline-3-carboxamide containing sulfones as liver X receptor (LXR) agonists with binding selectivity for LXRbeta and low blood-brain penetration.

Anna Wilhelmsson, P. Nambi, M. Evans, 2010, Bioorganic & medicinal chemistry letters.

Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator.

M. Emery, A. Goos-Nilsson, N. Tu, 2004, Bioorganic & medicinal chemistry letters.

Hepatic Glucocorticoid Receptor Antagonism Is Sufficient to Reduce Elevated Hepatic Glucose Output and Improve Glucose Control in Animal Models of Type 2 Diabetes

L. Öhman, D. Edgerton, A. Cherrington, 2005, Journal of Pharmacology and Experimental Therapeutics.

Synthesis, activity, metabolic stability, and pharmacokinetics of glucocorticoid receptor modulator-statin hybrids.

M. Emery, S. Fung, Jiahong Wang, 2004, Bioorganic & medicinal chemistry letters.

Parallel strategies for the preparation and selection of liver-targeted glucocorticoid receptor antagonists.

G. L. Hamilton, B. J. Backes, S. Fung, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and activity of novel bile-acid conjugated glucocorticoid receptor antagonists.

S. Richards, S. Fung, Jiahong Wang, 2006, Bioorganic & medicinal chemistry letters.

Discovery of novel nonsteroidal glucocorticoid receptor modulators.

Jyoti R. Patel, M. Emery, A. Goos-Nilsson, 2004, Bioorganic & medicinal chemistry letters.

Further modification on phenyl acetic acid based quinolines as liver X receptor modulators.

Farooq Azam, Anna Wilhelmsson, James Jetter, 2007, Bioorganic & medicinal chemistry.

Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis.

Christopher Miller, Farooq Azam, Anna Wilhelmsson, 2006, Journal of medicinal chemistry.

Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRbeta.

P. Nambi, Baihua Hu, Raymound Unwalla, 2009, Bioorganic & medicinal chemistry.

Biarylether amide quinolines as liver X receptor agonists.

Anna Wilhelmsson, John Ullrich, P. Nambi, 2009, Bioorganic & medicinal chemistry.

3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists.

Robert Steffan, Anna Wilhelmsson, P. Nambi, 2010, Bioorganic & medicinal chemistry letters.

Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.

David C. Wood, K. Fennell, R. Kurumbail, 2018, Journal of medicinal chemistry.

An evaluation of a C-glucuronide as a liver targeting group: conjugate of a glucocorticoid antagonist.

M. Emery, Jiahong Wang, J. Link, 2003, Bioorganic & medicinal chemistry letters.

1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists.

Anna Wilhelmsson, P. Nambi, R. Bernotas, 2010, Bioorganic & medicinal chemistry letters.

Differential transcriptional regulation of the apoAI gene by retinoic acid receptor homo- and heterodimers in yeast.

P. Mak, H. Ahola, A. Goos-Nilsson, 1996, Nucleic acids research.

4-(3-Aryloxyaryl)quinoline sulfones are potent liver X receptor agonists.

Anna Wilhelmsson, P. Nambi, M. Evans, 2010, Bioorganic & medicinal chemistry letters.

Synthesis of 4-(3-biaryl)quinoline sulfones as potent liver X receptor agonists.

Anna Wilhelmsson, James Jetter, P. Nambi, 2010, Bioorganic & medicinal chemistry letters.

Carboxylic acid based quinolines as liver X receptor modulators that have LXRbeta receptor binding selectivity.

Lisa Nogle, Anna Wilhelmsson, James Jetter, 2008, Bioorganic & medicinal chemistry letters.

Antidiabetic activity of passive nonsteroidal glucocorticoid receptor modulators.

Jyoti R. Patel, T. Reisch, Z. Tian, 2005, Journal of medicinal chemistry.

Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes.

K. Koehler, L. Hagberg, C. Jakob, 2004, Journal of medicinal chemistry.

4-(3-aryloxyaryl)quinoline alcohols are liver X receptor agonists.

Anna Wilhelmsson, John Ullrich, P. Nambi, 2009, Bioorganic & medicinal chemistry.