J. Ngeow

发表

C. Eng, J. Ngeow, 2019, Cold Spring Harbor perspectives in medicine.

Understanding the Psychological Impact of COVID-19 Pandemic on Patients With Cancer, Their Caregivers, and Health Care Workers in Singapore

K. Griva, Z. L. T. Ang, J. Tuan, 2020, JCO global oncology.

Clinical implementation of an oncology‐specific family health history risk assessment tool

G. Ginsburg, D. Matchar, R. Myers, 2021, Hereditary cancer in clinical practice.

Hereditary diffuse gastric cancer: What the clinician should know.

J. Ngeow, R. Tan, 2015, World journal of gastrointestinal oncology.

CDKN2A germline alterations and the relevance of genotype-phenotype associations in cancer predisposition

J. Ngeow, J. Chiang, J. Ngeow, 2021, Hereditary Cancer in Clinical Practice.

Germline hemizygous deletion of CDKN2A–CDKN2B locus in a patient presenting with Li–Fraumeni syndrome

S. Lincoln, Joseph T. S. Wee, B. Teh, 2016, npj Genomic Medicine.

Increased Prevalence of Eosinophilic Gastrointestinal Disorders in Pediatric PTEN Hamartoma Tumor Syndromes

Lisa J. Martin, Keith A. Marsolo, C. Eng, 2014, Journal of pediatric gastroenterology and nutrition.

65 YEARS OF THE DOUBLE HELIX: Genetics informs precision practice in the diagnosis and management of pheochromocytoma.

A. Tischler, W. Young, C. Eng, 2018, Endocrine-related cancer.

Germline Pathogenic Variants in Homologous Recombination and DNA Repair Genes in an Asian Cohort of Young-Onset Colorectal Cancer

I. Tan, P. Tan, John Carson Allen, 2018, JNCI cancer spectrum.

The management of BRCA1 and BRCA2 carriers in Singapore.

J. Chiang, J. Ngeow, 2020, Chinese clinical oncology.

Clinical relevance of screening checklists for detecting cancer predisposition syndromes in Asian childhood tumours

A. Loh, Shao-Tzu Li, Tarryn Shaw, 2018, npj Genomic Medicine.

Thyroid cancer genetics: how close are we to personalizing clinical management?

C. Eng, J. Ngeow, 2012, Personalized medicine.

Cost-effectiveness of olaparib maintenance therapy when used with and without restriction by BRCA1/2 mutation status for platinum-sensitive relapsed ovarian cancer

W. Chay, J. Ngeow, M. Aziz, 2021, Expert review of pharmacoeconomics & outcomes research.

Targeted therapies in the treatment of gastric cancer

S. Choo, I. Tan, J. Ngeow, 2011, Asia-Pacific journal of clinical oncology.

Detecting Germline PTEN Mutations Among At-Risk Patients With Cancer: An Age- and Sex-Specific Cost-Effectiveness Analysis.

Chang Liu, D. Matchar, C. Eng, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

An in-depth exploration of the post-test informational needs of BRCA1 and BRCA2 pathogenic variant carriers in Asia

B. Tan, Eliza Courtney, Tarryn Shaw, 2020, Hereditary cancer in clinical practice.

Understanding patients' views and willingness toward the use of telehealth in a cancer genetics service in Asia

Eliza Courtney, Tarryn Shaw, J. Chiang, 2021, Journal of genetic counseling.

PTEN mutations: help spot thyroid cancer before it occurs

C. Eng, J. Ngeow, 2012, Expert review of endocrinology & metabolism.

Inherited Thyroid Cancer

J. Ngeow, J. Lee, 2018 .

Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

Annette Lee, W. Chung, R. Nussbaum, 2018, Human mutation.

PTEN HAMARTOMA TUMOR SYNDROME

C. Eng, J. Ngeow, 2020, Cassidy and Allanson's Management of Genetic Syndromes.

Homologous recombination deficiency: cancer predispositions and treatment implications.

J. Ngeow, M. Toh, 2021, The oncologist.

Functional characterisation guides classification of novel BAP1 germline variants

B. Teh, H. Heng, J. Ngeow, 2020, npj Genomic Medicine.

Cost Effectiveness of Universal Hepatitis B Virus Screening in Patients Beginning Chemotherapy for Sarcomas or GI Stromal Tumors

D. Matchar, Ke Zhou, J. Ngeow, 2016, Journal of global oncology.

Molecular connections between circadian rhythm and genome maintenance pathways.

J. Ngeow, S. Chong, A. M. Kolinjivadi, 2020, Endocrine-related cancer.

Evil lurks in the heart of man: cardiac paraganglioma presenting as recurrent dyspnoea and chronic cough

P. Rajiah, C. Eng, J. Ngeow, 2011, BMJ Case Reports.

Second hematologic malignancies after ABVD: Two case reports and a retrospective study of 183 Hodgkin lymphoma patients

I. Tan, S. Lim, J. Ngeow, 2010, Acta oncologica.

Recurring mouth ulcer and skin rash in a man with abnormal chest radiograph.

A. Takano, J. Ngeow, S. Low, 2010, Chest.

PTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome.

C. Eng, M. Saji, M. Ringel, 2012, The Journal of clinical endocrinology and metabolism.

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

J. Thiery, B. Goh, S. Choo, 2019, Nature Communications.

Impact of Appointment Waiting Time on Attendance Rates at a Clinical Cancer Genetics Service

Eliza Courtney, Tarryn Shaw, J. Ngeow, 2018, Journal of Genetic Counseling.

Capecitabine-induced oromandibular dystonia: A case report and literature review

S. Choo, S. Quek, B. Chowbay, 2008, Acta oncologica.

Lifetime Cancer Risks in Individuals with Germline PTEN Mutations

C. Eng, M. Tan, L. Rybicki, 2012, Clinical Cancer Research.

A delayed diagnosis of Pallister-Hall syndrome in an adult male following the incidental detection of a hypothalamic hamartoma

Eliza Courtney, J. Ngeow, Diana Ishak, 2018, Human Genome Variation.

Health services utilisation and barriers for settlers from the Horn of Africa

S. Skull, B. Biggs, J. Ngeow, 2007, Australian and New Zealand journal of public health.

Automatic DNA replication tract measurement to assess replication and repair dynamics at the single-molecule level

Ong Kok Haur, Weimiao Yu, Laurent Gole, 2022, Bioinform..

Undiagnosed and potentially lethal parasite infections among immigrants and refugees in Australia.

H. Kelly, S. Skull, B. Biggs, 2006, Journal of travel medicine.

Incomplete Immunity and Missed Vaccination Opportunities in East African Immigrants Settling in Australia

S. Skull, B. Biggs, G. Hogg, 2008, Journal of Immigrant and Minority Health.

Comparative analysis of extra‐nodal NK/T‐cell lymphoma and peripheral T‐cell lymphoma: significant differences in clinical characteristics and prognosis

M. Tan, S. Hee, M. Ang, 2007, European journal of haematology.

Nuclear expression of MATK is a novel marker of type II enteropathy-associated T-cell lymphoma

K. Dykema, K. Furge, B. Teh, 2011, Leukemia.

Omics-Based Biomarker Discovery for Barrett’s Esophagus: All Bark and No Bite?

J. Ngeow, 2013 .

Familial non-medullary thyroid cancer: unraveling the genetic maze.

Samantha Peiling Yang, J. Ngeow, 2016, Endocrine-related cancer.

Germline mutation contribution to chromosomal instability.

J. Ngeow, Sock Hoai Chan, S. H. Chan, 2017, Endocrine-related cancer.

Evaluation of the methods to identify patients who may benefit from PARP inhibitor use.

D. Lim, J. Ngeow, 2016, Endocrine-related cancer.

Functional analysis of clinical BARD1 germline variants

Eliza Courtney, J. Lim, J. Ngeow, 2019, Cold Spring Harbor molecular case studies.

IL13RA2 is differentially regulated in Papillary Thyroid Carcinoma versus Follicular Thyroid Carcinoma.

C. Eng, C. Sturgis, Jiancheng Hu, 2019, The Journal of clinical endocrinology and metabolism.

RASAL1 in thyroid cancer: wisdom from an old foe.

C. Eng, J. Ngeow, 2013, Journal of the National Cancer Institute.

Telomere biology disorders

T. Nguyen, J. Ngeow, Michelle Li Wei Kam, 2021, npj Genomic Medicine.

Hereditary Syndromes Manifesting as Endometrial Carcinoma: How Can Pathological Features Aid Risk Assessment?

J. Ngeow, Adele Wong, 2015, BioMed research international.

Second malignant neoplasms in patients with Cowden syndrome with underlying germline PTEN mutations.

J. Barnholtz-Sloan, C. Eng, J. Mester, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Germline Heterozygous Variants in SEC23B Are Associated with Cowden Syndrome and Enriched in Apparently Sporadic Thyroid Cancer.

C. Eng, R. Keri, F. Niazi, 2015, American journal of human genetics.

65 YEARS OF THE DOUBLE HELIX: The advancements of gene editing and potential application to hereditary cancer.

Taosheng Huang, Zi-Ying Tan, J. Ngeow, 2018, Endocrine-related cancer.

Germline and somatic SDHx alterations in apparently sporadic differentiated thyroid cancer

R. Nagy, R. Kloos, T. LaFramboise, 2015, Endocrine-related cancer.

Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant

J. Chiang, J. Ngeow, Daniel Tan Shao Weng, 2022, Cold Spring Harbor molecular case studies.

PTEN-opathies: from biological insights to evidence-based precision medicine.

C. Eng, Lamis Yehia, J. Ngeow, 2019, The Journal of clinical investigation.

Studying Kidney Diseases Using Organoid Models

J. Ngeow, Meng Liu, Yun Xia, 2022, Frontiers in Cell and Developmental Biology.

Clinical relevance of screening checklists for detecting cancer predisposition syndromes in Asian childhood tumours

A. Loh, Tarryn Shaw, W. K. Lim, 2018, npj Genomic Medicine.

Evaluation of the relative effectiveness of the 2017 updated Manchester scoring system for predicting BRCA1/2 mutations in a Southeast Asian country

J. Allen, D. G. Evans, Eliza Courtney, 2017, Journal of Medical Genetics.

Emerging functions of Fanconi Anemia genes in replication fork protection pathways.

Wayne M Crismani, J. Ngeow, A. M. Kolinjivadi, 2020, Human molecular genetics.

Incidence and clinical characteristics of thyroid cancer in prospective series of individuals with Cowden and Cowden-like syndrome characterized by germline PTEN, SDH, or KLLN alterations.

C. Eng, L. Rybicki, J. Mester, 2011, The Journal of clinical endocrinology and metabolism.

Into the eye of the storm: breast cancer's somatic mutation landscape points to DNA damage and repair.

C. Eng, J. Ngeow, Emily Nizialek, 2013, Translational cancer research.

Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes.

C. Eng, T. Romigh, J. Mester, 2012, The Journal of clinical endocrinology and metabolism.

Preventive medicine of von Hippel-Lindau disease-associated pancreatic neuroendocrine tumors.

H. Amthauer, E. Jonasch, W. Young, 2018, Endocrine-related cancer.

Investigation into the origins of an ancient BRCA1 founder mutation identified among Chinese families in Singapore

M. Loh, Eliza Courtney, Tarryn Shaw, 2020, International journal of cancer.

TERT and BRAF in thyroid cancer: teaming up for trouble.

C. Eng, J. Ngeow, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Management of individuals with germline variants in PALB2: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)

W. Foulkes, R. Schmutzler, T. Pal, 2021, Genetics in Medicine.

Evaluating empowerment in genetic counseling using patient‐reported outcomes

Eliza Courtney, Yanni Chen, Jeanette Yuen, 2019, Clinical genetics.

Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas

K. Soo, B. Teh, P. Tan, 2017, Scientific Reports.

Spectrum of Germline Mutations Within Fanconi Anemia-Associated Genes Across Populations of Varying Ancestry.

W. K. Lim, J. Ngeow, Y. Ni, 2021, JNCI cancer spectrum.

Role of Polymorphisms in Cancer Susceptibility

I. Tan, P. Tan, J. Ngeow, 2010 .

Clinical Implications for Germline PTEN Spectrum Disorders.

C. Eng, Kaitlin Sesock, J. Ngeow, 2017, Endocrinology and metabolism clinics of North America.

Sarcomas Associated With Genetic Cancer Predisposition Syndromes: A Review.

J. Ngeow, M. Farid, 2016, The oncologist.

Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome.

C. Loddenkemper, S. Ehl, J. Maul, 2012, Gastroenterology.

Research Highlights: Highlights from the latest articles in personalized medicine.

C. Eng, J. Ngeow, 2013, Personalized medicine.

Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells

U. Sack, S. Ehl, Michael Loran Dustin, 2017, The Journal of allergy and clinical immunology.

Mutation spectrum of POLE and POLD1 mutations in South East Asian women presenting with grade 3 endometrioid endometrial carcinomas.

W. Hong, E. Loh, J. Tham, 2016, Gynecologic oncology.

Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta‐analysis

A. Talhouk, S. Leung, D. Huntsman, 2021, Cancer.

Prognostic factors in patients with diffuse large B cell lymphoma: Before and after the introduction of rituximab

M. Tan, S. Hee, M. Ang, 2008, Leukemia & lymphoma.

Reply to G. Le Flahec et al.

C. Eng, J. Ngeow, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

An International Collaborative Standardizing a Comprehensive Patient-Centered Outcomes Measurement Set for Colorectal Cancer

J. Borrás, R. Tollenaar, E. Van Cutsem, 2017, JAMA oncology.

Experience and Perceptions of a Family Health History Risk Assessment Tool among Multi-Ethnic Asian Breast Cancer Patients

G. Ginsburg, D. Matchar, Sungwon Yoon, 2021, Journal of personalized medicine.

The influence of Malay cultural beliefs on breast cancer screening and genetic testing: A focus group study

Eliza Courtney, Tarryn Shaw, D. Lie, 2018, Psycho-oncology.

Prognostic impact of bleomycin-induced pneumonitis on the outcome of Hodgkin’s lymphoma

I. Tan, R. Kanesvaran, S. Lim, 2010, Annals of Hematology.

Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps.

L. Aaltonen, J. Willis, J. Church, 2013, Gastroenterology.

Exome Sequencing Reveals Germline SMAD9 Mutation That Reduces Phosphatase and Tensin Homolog Expression and Is Associated With Hamartomatous Polyposis and Gastrointestinal Ganglioneuromas.

L. Tucker-Kellogg, C. Eng, Haiwei Song, 2015, Gastroenterology.

PTEN Hamartoma Tumour Syndrome:Gastrointestinal Manifestations ofTwo Cases Diagnosed in Singapore

J. Ngeow, Lee Hy, Cheah Py, 2015 .

Mismatch Repair Deficiency in Colorectal Cancers: Is Somatic Genomic Testing the Grab-Bag for All Answers?

C. Eng, J. Ngeow, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Rectal Cancer: Age Matters in the Affairs of Stage.

C. Eng, J. Ngeow, 2016, Journal of the National Cancer Institute.

Rectal Cancer: Age Matters in the Affairs of Stage.

C. Eng, J. Ngeow, 2015, Journal of the National Cancer Institute.

Population-based universal screening for Lynch syndrome: ready, set... How?

C. Eng, J. Ngeow, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Germline breast cancer susceptibility genes, tumor characteristics, and survival

Jingmei Li, D. Easton, A. Dunning, 2021, Genome Medicine.

High SUV uptake on FDG-PET/CT predicts for an aggressive B-cell lymphoma in a prospective study of primary FDG-PET/CT staging in lymphoma.

S. Hee, L. Lim, J. Ngeow, 2009, Annals of oncology : official journal of the European Society for Medical Oncology.

The Singapore Liver Cancer Recurrence (SLICER) Score for Relapse Prediction in Patients with Surgically Resected Hepatocellular Carcinoma

P. Chow, S. Choo, P. Cheow, 2015, PloS one.

Using Quality Improvement Methods and Time-Driven Activity-Based Costing to Improve Value-Based Cancer Care Delivery at a Cancer Genetics Clinic.

Khee Chee Soo, Thomas W Feeley, K. Soo, 2016, Journal of oncology practice.

Oh GxE! The Complexity of Body Mass Index and Colon Cancer Risk.

C. Eng, J. Ngeow, 2020, Journal of the National Cancer Institute.

OP-JNCI200061 5..6

C. Eng, J. Ngeow, 2020 .

CDKN2A germline alterations and the relevance of genotype-phenotype associations in cancer predisposition

J. Chiang, J. Ngeow, Sock Hoai Chan, 2021, Hereditary cancer in clinical practice.

Correction: The Singapore Liver Cancer Recurrence (SLICER) Score for Relapse Prediction in Patients with Surgically Resected Hepatocellular Carcinoma

P. Chow, S. Choo, P. Cheow, 2015, PloS one.

HABP2 in Familial Nonmedullary Thyroid Cancer: Will the Real Mutation Please Stand Up?

C. Eng, J. Ngeow, 2016 .

A multimodality approach to reversible paraneoplastic encephalitis associated with ovarian teratomas

M. Tan, J. Dalmau, K. Chuah, 2009, Acta oncologica.

Multiple neoplasia in a patient with Gitelman syndrome harboring germline monoallelic MUTYH mutation.

Arnoud Boot, M. Chew, J. Chan, 2020, npj Genomic Medicine.

Germline PTEN, SDHB‐D, and KLLN alterations in endometrial cancer patients with Cowden and Cowden‐like syndromes: An international, multicenter, prospective study

C. Eng, J. Mester, C. Michener, 2015, Cancer.

Germline alterations in RASAL1 in Cowden syndrome patients presenting with follicular thyroid cancer and in individuals with apparently sporadic epithelial thyroid cancer.

C. Eng, G. Bebek, J. Ngeow, 2014, The Journal of clinical endocrinology and metabolism.

Germline PTEN Mutation Analysis for PTEN Hamartoma Tumor Syndrome.

C. Eng, J. Ngeow, 2016, Methods in molecular biology.

Docetaxel is effective in heavily pretreated patients with disseminated nasopharyngeal carcinoma.

E. Tan, J. Ngeow, M. Ang, 2011, Annals of oncology : official journal of the European Society for Medical Oncology.

Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas

K. Soo, B. Teh, P. Tan, 2017, Scientific Reports.

BluepRINT for moderate-to-low penetrance cancer susceptibility genes needed: breast cancer and beyond.

C. Eng, J. Ngeow, 2014, Cancer discovery.

HABP2 in Familial Non-medullary Thyroid Cancer: Will the Real Mutation Please Stand Up?