Daniel H. Scharf

发表

The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes

A. Brakhage, P. Hortschansky, H. Haas, 2009, Nucleic acids research.

Flavoenzyme-catalyzed formation of disulfide bonds in natural products.

M. Groll, A. Brakhage, T. Heinekamp, 2014, Angewandte Chemie.

Transannular disulfide formation in gliotoxin biosynthesis and its role in self-resistance of the human pathogen Aspergillus fumigatus.

A. Brakhage, T. Heinekamp, P. Hortschansky, 2010, Journal of the American Chemical Society.

Biosynthesis and function of gliotoxin in Aspergillus fumigatus

Axel A. Brakhage, A. Brakhage, T. Heinekamp, 2011, Applied Microbiology and Biotechnology.

N‐Heterocyclization in Gliotoxin Biosynthesis is Catalyzed by a Distinct Cytochrome P450 Monooxygenase

A. Brakhage, T. Heinekamp, Pranatchareeya Chankhamjon, 2020, Chembiochem : a European journal of chemical biology.

Star-shaped drug carriers for doxorubicin with POEGMA and POEtOxMA brush-like shells: a structural, physical, and biological comparison.

U. Schubert, F. Schacher, A. Brakhage, 2013, Biomacromolecules.

Redirection of acyl donor metabolic flux for lipopeptide A40926B0 biosynthesis

Xin-ai Chen, Yong-Quan Li, Qing-wei Zhao, 2022, Microbial biotechnology.

Gliotoxin--bane or boon?

A. Brakhage, P. Mukherjee, Daniel H. Scharf, 2016, Environmental microbiology.

Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway.

A. Brakhage, T. Heinekamp, Pranatchareeya Chankhamjon, 2012, Angewandte Chemie.

Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus Verticillium hemipterigenum

R. Guthke, J. Linde, A. Brakhage, 2015, Genome Announcements.

Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin

M. Groll, A. Brakhage, C. Hertweck, 2021, Angewandte Chemie.

A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis.

A. Brakhage, T. Heinekamp, P. Hortschansky, 2011, Journal of the American Chemical Society.

A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity

Bharat Rash, A. Brakhage, M. Strassburger, 2017, mBio.

Opposed effects of enzymatic gliotoxin N- and S-methylations.

A. Brakhage, T. Heinekamp, C. Hertweck, 2014, Journal of the American Chemical Society.

Identification of Immunogenic Antigens from Aspergillus fumigatus by Direct Multiparameter Characterization of Specific Conventional and Regulatory CD4+ T Cells

A. Scheffold, S. Dübel, Martin Vödisch, 2014, The Journal of Immunology.

Anion receptors based on halogen bonding with halo-1,2,3-triazoliums.

U. Schubert, H. Görls, C. Friebe, 2015, The Journal of organic chemistry.

Enzymatic Carbon-Sulfur Bond Formation in Natural Product Biosynthesis.

C. Hertweck, Kyle L. Dunbar, Daniel H. Scharf, 2017, Chemical reviews.

Aspects on evolution of fungal beta-lactam biosynthesis gene clusters and recruitment of trans-acting factors.

A. Brakhage, P. Hortschansky, Petra Sproete, 2009, Phytochemistry.

Human and Plant Fungal Pathogens: The Role of Secondary Metabolites

A. Brakhage, T. Heinekamp, Daniel H. Scharf, 2014, PLoS pathogens.

Identification of the novel penicillin biosynthesis gene aatB of Aspergillus nidulans and its putative evolutionary relationship to this fungal secondary metabolism gene cluster

A. Brakhage, P. Hortschansky, E. Shelest, 2008, Molecular microbiology.

Structural insights into ligand recognition and activation of the melanocortin-4 receptor

Tingjun Hou, Tianhua Zhou, Ming-Wei Wang, 2021, Cell Research.

DNA minor groove sensing and widening by the CCAAT-binding complex.

M. Groll, A. Brakhage, P. Hortschansky, 2012, Structure.

Engineering fungal secondary metabolism: a roadmap to novel compounds.

A. Brakhage, Daniel H. Scharf, 2013, Journal of biotechnology.

Epidithiodiketopiperazine biosynthesis: a four-enzyme cascade converts glutathione conjugates into transannular disulfide bridges.

A. Brakhage, T. Heinekamp, Pranatchareeya Chankhamjon, 2013, Angewandte Chemie.

Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ.

M. Groll, A. Brakhage, M. Glaser, 2017, ACS chemical biology.

Genetic Engineering Activates Biosynthesis of Aromatic Fumaric Acid Amides in the Human Pathogen Aspergillus fumigatus

A. Brakhage, T. Heinekamp, D. Hoffmeister, 2014, Applied and Environmental Microbiology.

Urease of Aspergillus fumigatus Is Required for Survival in Macrophages and Virulence

Yi Han, Daniel H. Scharf, Jarukitt Limwachiranon, 2023, Microbiology spectrum.

Reconstitution of Enzymatic Carbon-Sulfur Bond Formation Reveals Detoxification-Like Strategy in Fungal Toxin Biosynthesis.

A. Brakhage, T. Heinekamp, Pranatchareeya Chankhamjon, 2018, ACS chemical biology.

Degradation mechanism of AtrA mediated by ClpXP and its application in daptomycin production in Streptomyces roseosporus

Qingwei Zhao, Yongquan Li, Daniel H. Scharf, 2023, Protein science : a publication of the Protein Society.

Impact of PpSpi1, a glycosylphosphatidylinositol-anchored cell wall glycoprotein, on cell wall defects of N-glycosylation-engineered Pichia pastoris

W. Guan, Daniel H. Scharf, Xiaodan Wu, 2023, mBio.

Aspects on evolution of fungal beta-lactam biosynthesis gene clusters and recruitment of trans-acting factors.

A. Brakhage, P. Hortschansky, Petra Sproete, 2009, Phytochemistry.