D. Lark

发表

Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload.

K. Fisher-Wellman, Chien‐Te Lin, Laura A. A. Gilliam, 2013, Free radical biology & medicine.

High-fat load: mechanism(s) of insulin resistance in skeletal muscle.

P. Neufer, K. Fisher-Wellman, D. Lark, 2012, International journal of obesity supplements.

Targeted Metabolomics Connects Thioredoxin-interacting Protein (TXNIP) to Mitochondrial Fuel Selection and Regulation of Specific Oxidoreductase Enzymes in Skeletal Muscle*

P. Neufer, O. Ilkayeva, D. Muoio, 2014, The Journal of Biological Chemistry.

NOVEL MECHANISMS GOVERNING SKELETAL MUSCLE MITOCHONDRIAL BIOENERGETICS : OXPHOS EFFICIENCY AND cAMP/PKA SIGNALING

D. Lark, 2014 .

Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice

A. Pozzi, D. Wasserman, L. Kang, 2016, Diabetes.

Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers.

P. Neufer, Terence E. Ryan, E. Anderson, 2016, American journal of physiology. Cell physiology.

Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuit.

P. Neufer, Terence E. Ryan, D. Muoio, 2015, The Biochemical journal.

Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle.

P. Neufer, P. Brophy, T. Gavin, 2011, The Biochemical journal.

Enhanced Mitochondrial Superoxide Scavenging Does Not Improve Muscle Insulin Action in the High Fat-Fed Mouse

P. Neufer, D. Wasserman, L. Kang, 2015, PloS one.

Reduced Nonexercise Activity Attenuates Negative Energy Balance in Mice Engaged in Voluntary Exercise

J. Lighton, D. Wasserman, L. Lantier, 2018, Diabetes.

Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle

P. Neufer, G. Heigenhauser, L. Spriet, 2012, The Journal of physiology.

Skeletal muscle tissue secretes more extracellular vesicles than white adipose tissue and myofibers are a major source ex vivo but not in vivo

Nicole A. Kruh-Garcia, D. Lark, A. Estrada, 2020, bioRxiv.

Do fish oil omega-3 fatty acids enhance antioxidant capacity and mitochondrial fatty acid oxidation in human atrial myocardium via PPARγ activation?

S. Shaikh, E. Anderson, J. Williams, 2014, Antioxidants & redox signaling.

The rise and fall of circulating miRNAs in response to exercise

D. Lark, 2022, Acta physiologica.

Expression of Exosome Biogenesis Genes is Pervasively Altered by Aging in the Mouse and in the Human Brain During Alzheimer's Disease

D. Lark, T. Larocca, T. LaRocca, 2021, medRxiv.

Extracellular vesicle secretion is tissue-dependent ex vivo and skeletal muscle myofiber extracellular vesicles reach the circulation in vivo.

N. Balestrieri, E. Spangenburg, Nicole A. Kruh-Garcia, 2021, American journal of physiology. Cell physiology.

Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study

E. Gamazon, O. Boutaud, Q. Wells, 2018, eLife.

A single dose of metformin improves whole body insulin sensitivity and alters cellular redox state in skeletal muscle of Zucker fa/fa rats

D. Lark, 2010 .

Mitochondrial Dynamics and Oxidative Stress Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction

P. Neufer, Terence E. Ryan, Chien‐Te Lin, 2016 .

Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy

R. Cone, J. Moslehi, J. Fessel, 2017, eLife.

Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner.

A. Pozzi, D. Wasserman, K. Boyd, 2019, American journal of physiology. Endocrinology and metabolism.

The reverse transcriptase inhibitor 3TC protects against age‐related cognitive dysfunction

C. Link, Shelby C. Osburn, Devin Wahl, 2023, Aging cell.

Protein Kinase A Governs Oxidative Phosphorylation Kinetics and Oxidant Emitting Potential at Complex I

P. Neufer, Terence E. Ryan, Chien‐Te Lin, 2015, Front. Physiol..

Expression of Exosome Biogenesis Genes is Differentially Altered by Aging in the Mouse and in the Human Brain During Alzheimer's Disease.

D. Lark, T. LaRocca, 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.

Meta-fibrosis links positive energy balance and mitochondrial metabolism to insulin resistance

D. Wasserman, D. Lark, 2017, F1000Research.

Parkin sarcopenia in its tracks by improving mitochondrial health

D. Lark, A. Estrada, Z. Valenti, 2019, The Journal of physiology.

Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload.

Chien‐Te Lin, Laura A. A. Gilliam, Brook L. Cathey, 2013, Free radical biology & medicine.

Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction.

Chien‐Te Lin, Maria.J. Torres, Laura A. A. Gilliam, 2016, American journal of physiology. Endocrinology and metabolism.

Accelerated aging of the brain transcriptome by the common chemotherapeutic doxorubicin

S. Melov, D. Seals, J. Campisi, 2021, Experimental Gerontology.

Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle

P. Neufer, L. Spriet, G. Heigenhauser, 2012, The Journal of physiology.

Circulating Tetraspanins: From Markers to Mechanisms Driving Systemic Exercise Adaptation

D. Lark, Darby S Easterday, 2023, Function.