Xin Lu

发表

STING, a promising target for small molecular immune modulator: A review.

Wenyuan Liu, F. Feng, Yijun Liu, 2020, European journal of medicinal chemistry.

The Development of Pharmacophore Modeling: Generation and Recent Applications in Drug Discovery.

Xin Lu, Hongyu Yang, Wei Qu, 2018, Current pharmaceutical design.

Expansion of the scaffold diversity for the development of highly selective butyrylcholinesterase (BChE) inhibitors: Discovery of new hits through the pharmacophore model generation, virtual screening and molecular dynamics simulation.

Q. Guo, Wenyuan Liu, F. Feng, 2019, Bioorganic chemistry.

Synthesis and inhibitory evaluation of cyclohexen-2-yl- and cyclohexyl-substituted phenols and quinones to endothelial cell and cancer cells.

Xin Liu, Xin Lu, Guo-Chun Zhou, 2010, European journal of medicinal chemistry.

Synthesis of tricyclic quinazolinone-iminosugars as potential glycosidase inhibitors via a Mitsunobu reaction.

Xiao-liu Li, Xin Lu, Hua Chen, 2019, Carbohydrate research.

N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease.

W. Li, Wenyuan Liu, F. Feng, 2022, Journal of medicinal chemistry.

Botryoisocoumarin A, a new COX-2 inhibitor from the mangrove Kandelia candel endophytic fungus Botryosphaeria sp. KcF6

Yonghong Liu, Zheng-chao Tu, Junfeng Wang, 2015, The Journal of Antibiotics.

Cytotoxic and antiviral nitrobenzoyl sesquiterpenoids from the marine-derived fungus Aspergillus ochraceus Jcma1F17

Bin Yang, Yonghong Liu, Zheng-chao Tu, 2014 .

Design, synthesis, and biological evaluation of aromatic tertiary amine derivatives as selective butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease.

Wenyuan Liu, F. Feng, Yijun Liu, 2022, European journal of medicinal chemistry.

Synthesis of Deuterated Benzopyran Derivatives as Selective COX-2 Inhibitors with Improved Pharmacokinetic Properties.

Yanmei Zhang, J. Talley, Zheng-chao Tu, 2014, ACS medicinal chemistry letters.

Highly potent dipeptidyl peptidase IV inhibitors derived from Alogliptin through pharmacophore hybridization and lead optimization.

Hongjian Xu, Zheng-chao Tu, Wenhui Hu, 2013, European journal of medicinal chemistry.

Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy.

Xin Lu, Qi Li, Feng Feng, 2017, Journal of medicinal chemistry.

Eight new polyketide metabolites from the fungus Pestalotiopsis vaccinii endogenous with the mangrove plant Kandelia candel (L.) Druce

Xiaoyi Wei, Bin Yang, Yonghong Liu, 2014 .

Design, synthesis and discovery of 5-hydroxyaurone derivatives as growth inhibitors against HUVEC and some cancer cell lines.

Xin Lu, Guo-Chun Zhou, Y. Liu, 2010, European journal of medicinal chemistry.

Novel BuChE-IDO1 inhibitors from sertaconazole: Virtual screening, chemical optimization and molecular modeling studies.

Yijun Liu, Xin Lu, Haopeng Sun, 2020, Bioorganic & medicinal chemistry letters.

Discovery of a Selective 6-Hydroxy-1, 4-Diazepan-2-one Containing Butyrylcholinesterase Inhibitor by Virtual Screening and MM-GBSA Rescoring

Xin Lu, Haopeng Sun, K. H. Hong, 2020, Dose-response : a publication of International Hormesis Society.

Discovery of Selective Butyrylcholinesterase (BChE) Inhibitors through a Combination of Computational Studies and Biological Evaluations

Q. Xia, Xin Lu, Li Xu, 2019, Molecules.

Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry.

F. Feng, Yijun Liu, Xin Lu, 2020, European journal of medicinal chemistry.

Synthesis of tricyclic benzimidazole-iminosugars as potential glycosidase inhibitors via a Mitsunobu reaction.

Xiao-liu Li, Xin Lu, H. Lui, 2019, Carbohydrate research.

Cladosporone A, a new dimeric tetralone from fungus Cladosporium sp. KcFL6’ derived of mangrove plant Kandelia candel

Yonghong Liu, Xianwen Yang, Zheng-chao Tu, 2014, The Journal of Antibiotics.

Synthesis and activity of miconazole derivatives as dual BChE/IDO1 inhibitors for the treatment of Alzheimer's disease.

Wenyuan Liu, F. Feng, Yijun Liu, 2021, Future medicinal chemistry.

Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer's disease.

F. Feng, Yaoyao Bian, Xin Lu, 2018, Bioorganic & medicinal chemistry.

New Compounds from Euphorbia helioscopia and Absolute Configuration Determination by Computational Methods

Xin Lu, Guo-Chun Zhou, Hua-Jie Zhu, 2010 .

A new naphthalene glycoside from the sponge-derived fungus Arthrinium sp. ZSDS1-F3

Bin Yang, Yonghong Liu, Zheng-chao Tu, 2014, Natural product research.

Sesquiterpenoids and xanthones derivatives produced by sponge-derived fungus Stachybotry sp. HH1 ZSDS1F1-2

Yonghong Liu, Zheng-chao Tu, Shengrong Liao, 2014, The Journal of Antibiotics.

Discovery of potent dipeptidyl peptidase IV inhibitors through pharmacophore hybridization and hit-to-lead optimization.

Hongjian Xu, Zheng-chao Tu, Wenhui Hu, 2013, Bioorganic & medicinal chemistry.

Regulation of beta‐amyloid for the treatment of Alzheimer's disease: Research progress of therapeutic strategies and bioactive compounds

F. Feng, Lei Wang, Yijun Liu, 2023, Medicinal research reviews.

Design, synthesis, in vitro and in vivo evaluation of tacrine–cinnamic acid hybrids as multi-target acetyl- and butyrylcholinesterase inhibitors against Alzheimer's disease

Yuqiong Pei, R. Tan, Yaoyao Bian, 2017 .

Discovery, molecular dynamic simulation and biological evaluation of structurally diverse cholinesterase inhibitors with new scaffold through shape-based pharmacophore virtual screening.

Wenyuan Liu, F. Feng, Xin Lu, 2019, Bioorganic chemistry.

Gamma secretase inhibitors: a patent review (2013 - 2015)

Kai Gu, Xin Lu, Haopeng Sun, 2017, Expert opinion on therapeutic patents.

Synthesis, discovery and preliminary SAR study of benzofuran derivatives as angiogenesis inhibitors.

Hao Cheng, Yuan Chen, Xin Lu, 2009, Bioorganic & medicinal chemistry letters.

Novel pyrrolopyrimidine analogues as potent dipeptidyl peptidase IV inhibitors based on pharmacokinetic property-driven optimization.

Hongjian Xu, Zheng-chao Tu, Wenhui Hu, 2012, European journal of medicinal chemistry.

Evaluation of aminohydantoins as a novel class of antimalarial agents.

D. Griggs, D. Goldberg, Xiaoyun Lu, 2014, ACS medicinal chemistry letters.

Axinelline A, a new COX-2 inhibitor from Streptomyces axinellae SCSIO02208

Yonghong Liu, Zheng-chao Tu, Xiu-ping Lin, 2014, Natural product research.

Discovery of tryptophan‐tetrahydroisoquinoline derivatives as multifunctional agents for treatment of Alzheimer's disease

Yijun Liu, Xin Lu, Nan Qin, 2022, Chinese journal of chemistry.

A Practical and High‐Affinity Fluorescent Probe for Butyrylcholinesterase: A Good Strategy for Binding Affinity Characterization

Lei Wang, Yueqing Li, Xin Lu, 2022, Chinese journal of chemistry.